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All Journal bionature Majalah Obat Tradisional Sari Pediatri Majalah Kedokteran Andalas Mattawang: Jurnal Pengabdian Masyarakat Narra J Berita Kedokteran Masyarakat Bionature
Yusuf Yenni
Universitas Hasanuddin
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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Penggunaan Bakteri Bacillus spp untuk Pengendalian Jentik Nyamuk Anopheles spp (Application of Bacillus spp as Microbial Larvicides to Control Anopheles Larvae) Yenni Yusuf
Bionature Vol. 10 No. 2 (2009): Oktober 2009
Publisher : Jurusan Biologi Universitas Negeri Makassar

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Abstract

Based on the high incidence and fatality of malaria, a comprehensive management to control the disease, including Anopheles larval control to remove the transmission path, is urgently required. Chemical insecticides used for this purpose is claimed to be less environmentally safe and potentially increase the mosquito resistance. Thus, there is a need to use alternative insecticide. Some studies found that Bacillus sphaericus dan Bacillus thuringiensis israeli could effectively kill Anopheles larvae and has a low potency to increase resistency. Besides that, it is environmentally safe and does not affect non-target organisms. Therefore, the use of Bacillus spp as larvicides could be undertaken in malaria control programme especially in endemic areas.
Evaluasi Rasio Netrofil Limfosit (RNL) untuk diagnosis COVID-19 pada Pasien di RS Tadjuddin Chalid, Makassar, Indonesia Yenni Yusuf; Sitti Nurisyah; Ammar Abdurrahman Hasyim; Khaeriah Amru; Atifatul Qalbi Kadir; Azizah Nurul Mutia; Muhammad Naufal Zuhair; Kartika Paramita
Bionature Vol. 22 No. 2 (2021): Oktober 2021
Publisher : Jurusan Biologi Universitas Negeri Makassar

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The neutrophil lymphocyte ratio (NLR) is one of the variables related to the severity of COVID-19 disease. Therefore, we evaluated the value of NLR in COVID-19 patients and its relation to the symptoms and severity of COVID-19 at Tadjuddin Chalid Hospital, Makassar. We recruited patients visiting Tadjuddin Chalid Hospital Makassar who were willing to take part in the study in April to August 2021. Demographic, clinical and laboratory data were recorded through interviews and medical records. The severity of the disease is classified according to the guidelines from the association of Indonesian pulmonary doctors, Indonesian internal medicine doctors, Indonesian pediatricians, anesthesiologists and intensive care doctors, and the Indonesian cardiologist association. NLR data was obtained by calculating the ratio between neutrophil levels and lymphocyte levels in the blood. A total of 130 patients took part in the study, between 19-72 years old. There were 77 subjects (59.2%) with mild symptoms, 28 (21.6%) with moderate symptoms, and 25 (19.2%) with severe symptoms. There were 89 subjects with NLR <3.5 (68.5%) and 41 (10.8%) with NLR > 3.5. NLR values in patients with severe and moderate disease were significantly different from NLR in patients with mild disease (p =0.0002 dan p<0.0001, respectively). However, no significant difference was found in NLR between patients who neither have cough nor fever with those who had one or both of those symptoms. The presence of clinical or radiological symptoms of pneumonia accompanied by an NLR > 3.5 can be used as an indicator for a suspected moderate or severe COVID-19 diagnosis.
Tinjauan Molekuler dan Epidemiologi Mutasi pada Virus SARS-CoV-2 Hartono; Yenni Yusuf
Bionature Vol. 22 No. 1 (2021): April 2021
Publisher : Jurusan Biologi Universitas Negeri Makassar

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Virus SARS-CoV-2 yang merupakan penyebab pandemi COVID-19 sejakakhir tahun 2019 telah mengalami banyak mutasi yang memunculkan beberapavariants of concern (VOC) dengan penularan, virulensi, dan kemampuanmenghindari sistem imun yang lebih tinggi daripada varian awal (wild-type). Hinggakini terdapat empat varian yang termasuk dalam VOC virus tersebut yaitu varianalfa, beta, gamma, dan delta. Peningkatan transmisi dan virulensi pada VOC tersebutdikaitkan dengan perubahan mutasi pada protein spike yang merupakan strukturdari virus yang berperan dalam pengikatan dengan sel host. Pada artikel ini kamimelakukan literature review mengenai VOC dari virus SARS-CoV-2 terkait mutasiyang terjadi dan dampaknya pada proses pengikatan virus. Untuk mendapatkanpemahaman terkait dampak dari mutasi di berbagai varian tersebut, kami jugamereview struktur dari protein spike dan proses entry virus ke dalam sel host.
Co-Authors . Yuliastuti, . Abdullah, Arwini Avissa Aidah Juliaty, Aidah Amiruddin, Dianawaty Ammar Abdurrahman Hasyim Amru, Khaeriah Asih, Puji BS. Asri, Rangga Meidianto Atifatul Qalbi Kadir Azizah Nurul Mutia Banjar, Muhammad Fadhil Bukhari, Agussalim Din Syafruddin Djaharuddin, Irawaty Elim, Diany Fachry Abda El Rahman Fadhilah, Nur Azizah Go, Rivaldo Halik, Handayani Hartono Hartono Hartono Hartono Hartono Hasyim, Ammar A. Hasyim, Ammar Abdurrahman IRFAN IDRIS Itani, Kei Iyori, Mitsuhiro Junaedi, Ari Andini Kadir, Atifatul Qalbi Kaharuddin, Kania Meliani Kartika Paramita Maulani, Destya Mubin, Risna Halim Muhammad Naufal Zuhair Mutia, Azizah Nurul Nakamura, Kurumi Nurisyah, Sitti Parenden, Martrisna Dara Karnia Putri, Sri Hardiyanti Salekede, Setia Budi Saputra, Mesakh Diki Sitti Nurisyah Sitti Wahyuni Sumastuti Regina, Sumastuti Veithzal Rivai Zainal Yoshida, Shigeto Zainal, Kartika H. Zuhair, Muhammad Naufal