The primary aim of this study is to ascertain the learning preferences of junior high school students and evaluate their interest in mathematics following instruction utilizing e-comic media grounded in realistic mathematics education within a framework of differentiated learning. Employing a mixed methods approach with an exploratory sequential design, the study targets junior high school students in the West Bandung region, with a cohort of 30 eighth-grade students selected as the sample. Questionnaires serve as the primary instruments to discern students' learning styles. Qualitative analysis involves scrutinizing these styles vis-à-vis their learning requisites. The ensuing analysis informs the customization of instructional media tailored to students' preferences, subsequently validated by experts. The study culminates in administering interest assessment questionnaires post-instruction. Findings and data analysis reveal three predominant learning tendencies among students: visual (37%), auditory (20%), and kinesthetic dominated (43%). The developed instructional media, validated and tested for efficacy, effectively caters to these learning styles. Application of this media demonstrates heightened interest in learning mathematics compared to traditional instructional methods.