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All Journal ACTA VETERINARIA INDONESIANA Jurnal Agroqua: Media Informasi Agronomi dan Budidaya Perairan ARSHI Veterinary Letters Agroteknika Jurnal Politik Pemerintahan Dharma Praja Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal Ilmiah Biologi UMA (JIBIOMA) Proceeding International Seminar of Islamic Studies Jurnal Pusat Inovasi Masyarakat Jurnal Insan Jurnal Kedokteran Hewan Jurnal Dehasen Mengabdi Current Biomedicine
Anisa Rahma, Anisa
Jurusan Teknologi Hasil Pertanian, Fakultas Teknologi Pertanian, Universitas Jember
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Journal : Current Biomedicine

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Penyembuhan luka sayatan menggunakan krim ekstrak teripang laut dan kunyit Alpayet, Rahmat; Mustika, Aulia Andi; Rahma, Anisa; Andriyanto; Sutardi, Lina Noviyanti
Current Biomedicine Vol. 1 No. 2 (2023): July
Publisher : School of Veterinary Medicine and Biomedical Sciences, IPB University, Bogor, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/currbiomed.1.2.54-61

Abstract

Background: Skin is the outermost layer that covers and protects the body and is vulnerable to trauma, such as wounds. Turmeric and sea cucumbers are known to have properties in wound healing. Objective: This study aims to determine the effectiveness of a mixture of sea cucumber and turmeric extracts in the form of a cream to heal incision wounds in rats. Methods: Twenty-five male white rats, Sprague Dawley strain, and body weights of 250–300 g were anesthetized, and their skins were slashed. The rats were divided into five groups, namely negative control (wounds without treatment), positive controls (wounds treated with Bioplacenton® topically), and three treatment groups (wounds treated with sea cucumber and turmeric extract cream with concentrations of 0.5%, 1%, and 2% topically). Wound healing parameters were observed daily, namely accelerated wound closure and inflammation reduction. Data were analysed descriptively and tested using the non-parametric Kruskal-Wallis’s test. Results: The results showed that the wounds closed completely in all treated groups. Healing time in the group receiving treatment (positive control and concentration treatment of 0.5%, 1%, and 2% were 8.3 ± 1.5 days, 10.3 ± 0.6 days, 9.3 ± 0 .6 days, and 8.3 ± 1.5 days, respectively) faster than the healing time of the group that did not receive treatment (negative control was 12.6 ± 0.6 days). Conclusion: This study showed that sea cucumber and turmeric extract cream has the potential and is effective for wound healing and can be used as an alternative for wound treatment.
Efektivitas infusa buah jambu bol (Syzygium malaccense) sebagai antidiare pada mencit (Mus musculus) Santosa, Alfian; Purnawarman, Trioso; Mustika, Aulia Andi; Rahma, Anisa; Sutardi, Lina Noviyanti
Current Biomedicine Vol. 2 No. 1 (2024): January
Publisher : School of Veterinary Medicine and Biomedical Sciences, IPB University, Bogor, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/currbiomed.2.1.21-28

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Background: Malay rose apple (Syzygium malaccense) fruit has been used for a long time as a traditional medicine for diarrhea by the community. Malay rose apple fruit contains active compounds such as flavonoids, tannins, and terpenoids and could be used as an antidiarrheal drug. Objective: This study aims to test the effectiveness of the infusion of Malay rose apple fruit as an antidiarrheal agent in mice (Mus musculus). Methods: This research uses the method of intestinal protection and intestinal transit. The experimental animals in this study were 25 mice, which were divided into 5 groups, consisting of negative control (1% Tween 80), positive control group (loperamide HCl), and treatment groups using infusion of Malay rose apple fruit at concentrations of 50%, 75%, and 100%. The parameters assessed in the intestinal protection method are the frequency of defecation and the consistency of the stool, while the intestinal transit method is the ratio of marker passages. Results: The results showed that the antidiarrheal effect occurred at all concentrations. The best concentration as an antidiarrhea is shown by infusion with a concentration of 50%. The 50% concentration group had the smallest average on defecation frequency, stool consistency, and marker passage ratio compared to the values of the other treatment groups and was significantly different (P<0.05) compared to the value in the negative control. Conclusion: It can be concluded that the antidiarrheal effect of the infusion of Malay rose apple fruit occurs at all concentrations, with the best effect at a concentration of 50%.
Efficacy of tamarind leaf infusion (Tamarindus indica L.) as an antidiarrheal agent in mice Nababan, Ratna Kristiani; Sutardi, Lina Noviyanti; Rahma, Anisa; Mustika, Aulia Andi
Current Biomedicine Vol. 3 No. 2 (2025): July
Publisher : School of Veterinary Medicine and Biomedical Sciences, IPB University, Bogor, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/currbiomed.3.2.53

Abstract

Asam jawa merupakan tanaman herbal yang memiliki khasiat untuk mengobati berbagai penyakit, namun belum ada penelitian ilmiah mengenai aktivitas infusa daun asam jawa sebagai antidiare. Penelitian ini bertujuan untuk menentukan konsentrasi infusa daun asam jawa yang efektif dalam memberikan efek antidiare pada mencit. Penelitian ini juga bertujuan untuk menganalisis kandungan senyawa metabolit sekunder. Penelitian ini menggunakan 30 ekor mencit yang dibagi menjadi 5 kelompok yang terdiri dari kontrol negatif (Tween 80 [1%]), kontrol positif (Loperamid HCl), dan tiga kelompok yang diberi perlakuan infusa daun asam jawa dengan konsentrasi bertingkat (25%, 50 %, dan 100%). Parameter yang digunakan dalam metode proteksi usus adalah frekuensi buang air besar, konsistensi feses, waktu awal terjadinya diare, durasi, dan waktu penyembuhan diare. Hasil yang diperoleh menunjukkan ekstrak infusa daun asam jawa sebagai antidiare memiliki kemampuan menurunkan frekuensi defekasi, meningkatkan konsistensi feses, mencegah terjadinya diare, dan memperlama waktu penyembuhan diare. Hasil uji fitokimia dari infusa daun asam jawa mengandung flavonoid, steroid, dan terpenoid. Semua kelompok ekstrak infusa daun asam jawa memberikan hasil yang efektif sebagai antidiare.
Co-Authors A.S. Satyaningtijas Abi, Yudi Irawan Agung Priyono, Srihadi Agustin, Revalinda Alpayet, Rahmat Amaq Fadholly Andriyanto Anggraeni, Henny Endah Arimah, Sinta Aulia Andi Mustika Aulia, Nazuwa Bayu Febram Prasetyo Calista, Pradnya Dennis, Brandon Dwi Budiono Endah Rita Sulistya Dewi Fintri Indriyani George Edward, Nicolaas Hanadhita, Desrayni Heryudianto Vibowo Khairunnisa, Salis Lina Noviyanti Sutardi Lussana Rossita Dewi Madyastuti, Rini Maharani, Aulia Cinta Maheshwari2, Hera Maria Ulfah Melyani Sari Sitepu, Melyani Sari Muharomah, Nurul Ismah Nababan, Ratna Kristiani Nugraha, Ivan Taufiq Prawira, Andhika Yudha Putra Noerrizky, Ivandy Arifin Rahaman, Abdul Rahayu, Enny Rahmat, Kukuh Amru Dhiya Rasyid, Baharun Ridho, Ahmad Yusuf Romauli, Eztheriyhana Judika Salsabillah, Asyfa Thalita Santosa, Alfian Satriani, Slamet Savitri Novelina Setiyawan, Hazfi Sri Mulatsih Sri Rustianti Rustianti, Sri Rustianti Srihadi Agungpriyono Supratikno, Supratikno Tekad Urip Pambudi Sujarnoko Tommi Alfian Armawan Sandi Trioso Purnawarman Waliudin, Muhammad Sulthan Yulyanti, Oni Zonathan, Hendri