Zamroni Afif
Department Of Neurology School Of Medicine Brawijaya University

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Profil Probabilitas Stroke Iskemik Di Kota Malang Dan Batu: Aplikasi Skor Risiko Stroke Framingham Harahap, Herpan Syafii; Arisetijono, Eko; Afif, Zamroni
Jurnal Kedokteran Vol 5 No 3 (2016)
Publisher : Faculty of Medicine Universitas Mataram

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Abstract

Pendahuluan: Stroke saat ini merupakan salah satu penyebab kematian dan kecacatan utama di dunia, dimana 85% kasus merupakan stroke iskemik. Dengan mengetahui faktor-faktor risiko stroke iskemik, dapat dilakukan prediksi risiko untuk mengalami stroke iskemik dengan menggunakan skor risiko stroke Framingham. Tujuan: Untuk mengetahui profil probabilitas stroke iskemik di Kota Malang dan Batu menurut skor risiko stroke Framingham. Metode: Penelitian deskriptif cross-sectional ini menggunakan teknik consecutive random sampling untuk pengambilan sampel penelitian. Dilakukan pengukuran persentase dan stratifikasi skor risiko stroke Framingham terhadap 109 orang menurut jenis kelamin (n=109). Dalam penelitian ini juga dilakukan pengukuran parameter indeks massa tubuh (IMT), lingkar perut, rasio lingkar panggul-perut, dan kadar kolesterol total dan asam urat serum untuk dikorelasikan dengan persentase skor risiko stroke Framingham. Hasil: Sebanyak 72 orang (66,06%) memiliki risiko stroke iskemik yang rendah, 20 orang (18,34%) memiliki risiko sedang, dan 17 orang (15,60%) memiliki risiko tinggi. Hasil uji korelasi menunjukkan persentase risiko stroke memiliki korelasi negatif dengan IMT (p=0,030;r=-0,208) dan korelasi positif dengan kadar asam urat serum (p=0,018;r=0,244). Tidak didapatkan korelasi antara persentase skor risiko stroke Framingham dengan lingkar perut (p=0,120), rasio lingkar perut-panggul (p=0,070), dan kadar kolesterol total serum (p=0,208). Kesimpulan: Sepertiga sampel penelitian yang memiliki risiko stroke iskemik sedang-berat berdasarkan skor risiko stroke Framingham.
DANDY-WALKER VARIANT (DWV) IN 70 YEARS OLD WOMAN WITH DISEQUILIBRIUM AND CENTRAL VERTIGO : A CASE REPORT Ria Damayanti; Muhammad Welly Dafif; Shahdevi Nandar Kurniawan; Badrul Munir; Zamroni Afif
Journal of Pain, Headache and Vertigo Vol. 1 No. 1 (2020): March
Publisher : Journal of Pain, Headache and Vertigo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (298.776 KB) | DOI: 10.21776/ub.jphv.2020.001.01.2

Abstract

Dandy Walker Syndrome (DWS) and its Variants (DWV) is a congenital disorder that has prevalence of 1 in 25,000 to 30,000 births with the highest incidence occurs at age <1 year. However, patients may be diagnosed with DWS/DWV for the first time in adolescence and even old age. We reported the 70-year-old woman with a chief complaint of central type vertigo accompanied by disequilbrium. From history taking we obtained disequilibrium with gradual onset started in nine months and become settled since the last 6 months before she came to the neurology clinic. The patient also complained vertigo that have emerged since the last 3 month. A history of head trauma, stroke, dementia was denied. Physical examinaton show central nystagmus while other cranial nerve within normal range. Motor, sensory and autonomic status within normal range. Romberg test, tandem walking, disdiadokokinesia, and dismetria examination shows abnormal respons. MMSE results for patients within normal range (score:26). Head MRI shows Dandy Walker Variant in the accompanied by cerebral atrophy and degeneration serebelli Fazekas grade I. Patients receive symptomatic therapy betahistine mesylate 3x6 mg if necessary. Surgery management is not indicated because there is no sign of hydrocephalus or signs of increased intracranial pressure.
RADIOFREQUENCY AS PAIN INTERVENTIONAL THERAPY IN NEUROLOGY Badrul Munir; Widodo Mardi Santoso; Zamroni Afif; Shahdevi Nandar Kurniawan
Journal of Pain, Headache and Vertigo Vol. 1 No. 2 (2020): September
Publisher : Journal of Pain, Headache and Vertigo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (234.177 KB) | DOI: 10.21776/ub.jphv.2020.001.02.3

Abstract

Radiofrequency (RF) intervention uses high frequency alternating current (AC) to inhibit and alter nociceptive pathway in various locations. Radiofrequency is divided into Continuous RF (CRF) and Pulsed RF (PRF). Continuous RF is a process in which the RF current is used to produce thermal lesions on the target nerve that will result in resistance to the afferent nociceptive pathway. PRF is a process whereby short bursts of RF are discharged toward a neural target that will produce a signal for lowering pain. PRF is a therapy of neural tissue with small neurodestructive possibility and is an alternative technique for continuing RF. RF therapy is a minimally invasive procedure that has been used for about three decades to treat various chronic pain syndromes such as trigeminal neuralgia, post herpes neuralgia, lower back pain (LBP), and complex regional pain syndromes or sympathetic reflex dystrophy. The mechanism action of the PRF involves cellular structure damage, neuronal activation, altered gene expression, a global continuation of evoked synaptic  activity in pain fibers through centrals and changes in synaptic strength and long-term potentiation.  PRF with its various characteristics has a better outcome than conventional RF.
DIABETIC NEUROPATHIC PAIN Reza Rachmantoko; Zamroni Afif; Dessika Rahmawati; Rodhiyan Rakhmatiar; Shahdevi Nandar Kurniawan
Journal of Pain, Headache and Vertigo Vol. 2 No. 1 (2021): March
Publisher : Journal of Pain, Headache and Vertigo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (485.154 KB) | DOI: 10.21776/ub.jphv.2021.002.01.3

Abstract

Diabetic Neuropathy is the most common complication from diabetes, which experienced in almost 90% diabetes patient. Evenly pain is one of the most common symptoms of diabetic neuropathic, but the pathophysiology mechanism of pain is not clearly known. The hyptosesis of toxicity of hyperglycemia on development of pain complication has been widely accepted globally, but there is other proposed hypothesis. Basic concept in management of painful diabetic neuropathic is exclusion of the other cause of painful peripheral neuropathy, improving glycemic control for prophylaxis therapy and medication use for alleviating pain. The first choice drug of therapy for alleviating pain are anticonvulsant, like pregabalin and gabapentin, and antidepressant, mainly that work on inhibiting serotonine and noradrenaline reuptake. In conclusion, the better understanding of painful diabetic neuropathic underlying mechanism can help to find a better management that improving the guideline quality in optimalizing pain control.
MENIERE’S DISEASE Helena Era Millennie; Badrul Munir; Zamroni Afif; Ria Damayanti; Shahdevi Nandar Kurniawan
Journal of Pain, Headache and Vertigo Vol. 2 No. 1 (2021): March
Publisher : Journal of Pain, Headache and Vertigo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (492.36 KB) | DOI: 10.21776/ub.jphv.2021.002.01.5

Abstract

Meniere’s disease is a disorder of the inner ear resulting in symptoms of episodic vertigo, tinnitus, hearing loss and aural pressure. Although the exact etiology is uncertain, it is associated with raised pressure in the endolymph of the inner ear (endolymphatic hydrops). The diagnosis of Meniere's disease is based on the clinical setting of the patient. This disease usually presents with unilateral ear symptoms but can be also bilateral. Meniere's disease attacks are usually random and episodic (approximately  6-11 per year), with periods of remission that can last from months to years. Investigations are audiometry, electronystagmogram, vestibular evoked myogenic potentials (VEMPs) and imaging.The management consist pharmacological and non pharmacological. Meniere's disease is initially progressive but fluctuates unexpectedly. It is difficult to distinguish natural resolutions from treatment effects.
DANDY-WALKER VARIANT (DWV) IN 70 YEARS OLD WOMAN WITH DISEQUILIBRIUM AND CENTRAL VERTIGO : A CASE REPORT Ria Damayanti; Muhammad Welly Dafif; Shahdevi Nandar Kurniawan; Badrul Munir; Zamroni Afif
Journal of Pain, Headache and Vertigo Vol. 1 No. 1 (2020): March
Publisher : Journal of Pain, Headache and Vertigo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jphv.2020.001.01.2

Abstract

Dandy Walker Syndrome (DWS) and its Variants (DWV) is a congenital disorder that has prevalence of 1 in 25,000 to 30,000 births with the highest incidence occurs at age <1 year. However, patients may be diagnosed with DWS/DWV for the first time in adolescence and even old age. We reported the 70-year-old woman with a chief complaint of central type vertigo accompanied by disequilbrium. From history taking we obtained disequilibrium with gradual onset started in nine months and become settled since the last 6 months before she came to the neurology clinic. The patient also complained vertigo that have emerged since the last 3 month. A history of head trauma, stroke, dementia was denied. Physical examinaton show central nystagmus while other cranial nerve within normal range. Motor, sensory and autonomic status within normal range. Romberg test, tandem walking, disdiadokokinesia, and dismetria examination shows abnormal respons. MMSE results for patients within normal range (score:26). Head MRI shows Dandy Walker Variant in the accompanied by cerebral atrophy and degeneration serebelli Fazekas grade I. Patients receive symptomatic therapy betahistine mesylate 3x6 mg if necessary. Surgery management is not indicated because there is no sign of hydrocephalus or signs of increased intracranial pressure.
RADIOFREQUENCY AS PAIN INTERVENTIONAL THERAPY IN NEUROLOGY Badrul Munir; Widodo Mardi Santoso; Zamroni Afif; Shahdevi Nandar Kurniawan
Journal of Pain, Headache and Vertigo Vol. 1 No. 2 (2020): September
Publisher : Journal of Pain, Headache and Vertigo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jphv.2020.001.02.3

Abstract

Radiofrequency (RF) intervention uses high frequency alternating current (AC) to inhibit and alter nociceptive pathway in various locations. Radiofrequency is divided into Continuous RF (CRF) and Pulsed RF (PRF). Continuous RF is a process in which the RF current is used to produce thermal lesions on the target nerve that will result in resistance to the afferent nociceptive pathway. PRF is a process whereby short bursts of RF are discharged toward a neural target that will produce a signal for lowering pain. PRF is a therapy of neural tissue with small neurodestructive possibility and is an alternative technique for continuing RF. RF therapy is a minimally invasive procedure that has been used for about three decades to treat various chronic pain syndromes such as trigeminal neuralgia, post herpes neuralgia, lower back pain (LBP), and complex regional pain syndromes or sympathetic reflex dystrophy. The mechanism action of the PRF involves cellular structure damage, neuronal activation, altered gene expression, a global continuation of evoked synaptic  activity in pain fibers through centrals and changes in synaptic strength and long-term potentiation.  PRF with its various characteristics has a better outcome than conventional RF.
DIABETIC NEUROPATHIC PAIN Reza Rachmantoko; Zamroni Afif; Dessika Rahmawati; Rodhiyan Rakhmatiar; Shahdevi Nandar Kurniawan
Journal of Pain, Headache and Vertigo Vol. 2 No. 1 (2021): March
Publisher : Journal of Pain, Headache and Vertigo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jphv.2021.002.01.3

Abstract

Diabetic Neuropathy is the most common complication from diabetes, which experienced in almost 90% diabetes patient. Evenly pain is one of the most common symptoms of diabetic neuropathic, but the pathophysiology mechanism of pain is not clearly known. The hyptosesis of toxicity of hyperglycemia on development of pain complication has been widely accepted globally, but there is other proposed hypothesis. Basic concept in management of painful diabetic neuropathic is exclusion of the other cause of painful peripheral neuropathy, improving glycemic control for prophylaxis therapy and medication use for alleviating pain. The first choice drug of therapy for alleviating pain are anticonvulsant, like pregabalin and gabapentin, and antidepressant, mainly that work on inhibiting serotonine and noradrenaline reuptake. In conclusion, the better understanding of painful diabetic neuropathic underlying mechanism can help to find a better management that improving the guideline quality in optimalizing pain control.
MENIERE’S DISEASE Helena Era Millennie; Badrul Munir; Zamroni Afif; Ria Damayanti; Shahdevi Nandar Kurniawan
Journal of Pain, Headache and Vertigo Vol. 2 No. 1 (2021): March
Publisher : Journal of Pain, Headache and Vertigo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jphv.2021.002.01.5

Abstract

Meniere’s disease is a disorder of the inner ear resulting in symptoms of episodic vertigo, tinnitus, hearing loss and aural pressure. Although the exact etiology is uncertain, it is associated with raised pressure in the endolymph of the inner ear (endolymphatic hydrops). The diagnosis of Meniere's disease is based on the clinical setting of the patient. This disease usually presents with unilateral ear symptoms but can be also bilateral. Meniere's disease attacks are usually random and episodic (approximately  6-11 per year), with periods of remission that can last from months to years. Investigations are audiometry, electronystagmogram, vestibular evoked myogenic potentials (VEMPs) and imaging.The management consist pharmacological and non pharmacological. Meniere's disease is initially progressive but fluctuates unexpectedly. It is difficult to distinguish natural resolutions from treatment effects.
RELATIONSHIP BETWEEN DURATION OF UNTREATED PSYCHOSIS AND COGNITIVE FUNCTIONS USING MODIFIED SCORS (SCHIZOPHRENIA COGNITION RATING SCALE) IN SCHIZOPHRENIA PATIENTS IN SAIFUL ANWAR GENERAL HOSPITAL Dearisa Surya Yudhantara; Laksmi Muliawati; Zamroni Afif
Journal of Psychiatry Psychology and Behavioral Research Vol. 2 No. 1 (2021)
Publisher : Departemen Psikiatri Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (217.449 KB) | DOI: 10.21776/ub.jppbr.2021.002.01.2

Abstract

Mental health is a significant health problem in the world, including Indonesia. Lack of understanding and concern for the community, limitations and unequal distribution of mental health service provider also contribute to obstacles to increase public understanding and concern for mental health. This problem will give an impact on the difficulty of patients in accessing care and treatment. The emergence of the phenomenon of Duration of Untreated Psychosis (DUP) or untreated psychosis in society contributes to the worsening of the disease course of schizophrenic patients. One of the main clinical manifestations seen in schizophrenic patients is a decline in cognitive function. SCoRS is present as an easy and effective instrument in quantitatively measuring cognitive function. In the study used a modified SCoRS instrument that was more adapted to Indonesian’s culture. This study was conducted to determine the relationship between the duration of untreated psychosis and cognitive function using modified SCoRS, especially in schizophrenic patients at Saiful Anwar General Hospital. The research method used observational analytic with a cross-sectional approach. Selection of research subjects based on inclusion and exclusion criteria. Then do the appropriate history taking and psychiatric examination. Correlation analysis using Spearman to determine the relationship of variable duration of psychosis without therapy and cognitive function assessed using SCoRS modification (p <0.05). The results prove that there is a significant relationship between the variable duration of therapy without therapy and cognitive function variables assessed using SCoRS modification with a weak correlation level (correlation coefficient 0.340).