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All Journal BIOTROPIA - The Southeast Asian Journal of Tropical Biology Jurnal Sains dan Teknologi Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) JPSCR : Journal of Pharmaceutical Science and Clinical Research Jurnal Karinov Jurnal Ilmiah Medicamento Jurnal Kefarmasian Indonesia Journal Pharmaceutical Science and Application (JPSA)
Ni Made Dwi Mara Widyani Nayaka
Departemen Farmasi Bahan Alam, Fakultas Farmasi, Universitas Mahasaraswati Denpasar, Jl. Kamboja No.11A Denpasar, Indonesia, 80233.
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences Veterinary Other

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A REVIEW OF ANTIBACTERIAL POTENTIAL OF BANANGBANANG PLANT (Xylocarpus granatum J.Koenig) EXTRACT Galuh Bela Pertiwi; I Gusti Agung Ayu Kusuma Wardani; Ni Made Dwi Mara Widyani Nayaka
Journal Pharmaceutical Science and Application Vol. 5 No. 1 (2023): Journal Pharmaceutical Science and Application (JPSA)
Publisher : Pharmacy Department, Math and Sciences Faculty, Udayana Univerity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JPSA.2023.v05.i01.p03

Abstract

Background: Xylocarpus granatum has been used traditionally by coastal communities to treat various diseases. It is known that this plant contains secondary metabolites with various pharmacological activities, including as an antibacterial. Objective: This review article aims to provide information regarding the potential antibacterial activity of banangbanang plants and to summarize the content of compounds that have antibacterial properties and their mechanism of action. Methods: The preparation of this article is through literature studies from various international journals and national journals obtained online by taking into account predetermined inclusion and exclusion criteria. Then it was selected and studied further to obtain data related to the antibacterial activity of banangbanang plants and the content of secondary metabolites that have potential as antibacterials. Result: The banang-banang plant, especially the leaves, roots, fruit, seeds, fruit flesh, fruit peels, stems and bark with its secondary metabolites can inhibit several bacterial species such as Staphylococcus epidermidis, Pseudomonas aeruginosa, Escherichia coli, Vibrio alginolyticus, Staphylococcus aureus, Shigella boydii , Proteus spp., Streptococcus pyogenes, Ralstonia solanacaerum, Propionibacterium acnes, Agrobacterium tumefaciens, Aspergillus paraciticus, Bacillus subtilis, Candida albicans, Pseudomonas fluorescence, Micrococcus luteus, Saccharomyces ceresiviae, Salmonella typhi, Vibrio alginoliticus and Aeromonas hydrophilla. The secondary metabolites of this plant that have potential as antibacterial are tannins, saponins, steroids, phenols, triterpenoids, flavonoids, alkaloids, terpenoids and glycosides which have their respective mechanisms of action as antibacterial agents. Conclusion: Secondary metabolites contained in each part of the Xylocarpus granatum plant are thought to have a role in its antibacterial activity. Keywords: Antibacterial; Mechanism of action; Secondary metabolite; Xylocarpus granatum J.Koenig.
Co-Authors Agustini, Ni Putu Dewi Debby Juliadi Desak Ketut Ernawati Dwi Arymbhi Sanjaya Erna Cahyaningsih Galuh Bela Pertiwi Galuh Bela Pertiwi I Gusti Agung Ayu Kartika Indriani, Felia Riska Mahardika, I Made Agus Maria Malida Vernandes Sasadara Megawati, Fitria Ni Ketut Sinarsih Ni Luh Kade Arman Anita Dewi Ni Luh Kade Arman Anita Dewi Ni Luh Putu Swari Ni Made Dharma Shantini Suena Ni Nyoman Wahyu Udayani Ni Putu Gek Dyah Citra Vitaloka Ni Putu Udayana Antari puguh santoso, puguh Putra Hilmi Prayitno Putra, I Made Agus Sunadi Putu Era Sandhi Kusuma Yuda Sasadara, Maria Malida Vernandes Sukmayanti, Ni Kadek Suradnyana, I Gede Made Swari, Ni Luh Putu Wardani, I Gusti Agung Ayu Kusuma Wardani, I Gusti Ayu Agung Kusuma Widnyani, Dewa Ayu Sri Bintang