Article Per Year (5 Year)
p-Index From 2021 - 2026
0.408
P-Index
This Author published in this journals
All Journal JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA JURNAL KESEHATAN: JURNAL ILMIAH MULTI SCIENCES
Hairun Niza
Unknown Affiliation
Chemistry Education Health Professions Medicine & Pharmacology Nursing Public Health Other

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Identification of Drug Related Problems (DRPs) in Rheumatoid Arthritis Patients at Palembang City Hospital Hairun Niza; Sarah Hanifah Az-Zahra Anwar; Sintya Merinda
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 11 No. 1 (2024): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v11i12024.112-119

Abstract

Background: Rheumatoid arthritis is a chronic systemic inflammatory arthritis disease that affects mainly synovial joints. The incident of RA can lead to the emergence of complications or comorbidities, which then allows patients to receive a variety of therapies that can trigger the incidence of DRPs during the treatment. The prevalence of RA in Indonesia itself in 2018 has reached 7.30%, with the highest percentage occurring in the elderly age group and more prevalent in women. Objective: This study aimed to determine the incidence of DRPs in RA patients in Palembang city hospitals based on the category of DRPs identified as related to drug selection and dose selection problems, as the relationship between demographic factors and the incidence of DRPs. Methods: This research is non-experimental study conducted with a retrospective cross-sectional survey. Data collection was carried out by looking at patient medical record data at X and Y Hospital in Palembang from January 2021 to March 2023. Results: The results showed that the most frequent drps in the drug selection category were drug interactions (72.03%), while in the dose selection category were insufficient dosage regimens (60.74%). The results of bivariate analysis between the incidence of DRPs and gender (p=0.809), age (p=0.879), the number of drugs used (p=0.001), and comorbidities (p=0.089). Conclusion: There is no relationship between demographic factors and comorbidities with the incidence of DRPs, and there is a relationship between the number of drugs and the incidence of DRPs.
UJI EFEKTIVITAS PEMBERIAN EKSTRAK ETANOL DAUN RAMBUTAN (Nephelium lapaccum L.) TERHADAP PENURUNAN KADAR ASAM URAT MENCIT PUTIH JANTAN Hairun Niza; Rina SE Sitindaon; Dwi Intan Permata Sari
Jurnal Kesehatan : Jurnal Ilmiah Multi Sciences Vol 14 No 1 (2024): JURNAL KESEHATAN : JURNAL ILMIAH MULTI SCIENCES
Publisher : STIK SITI KHADIJAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52395/jkjims.v14i1.411

Abstract

Tanaman tradisional yang berkhasiat sebagai obat yang mempunyai sifat antihiperurisemia yaitu daun rambutan yang diketahui memiliki manfaat untuk pengobatan hiperkolestrol dan dapat menurunkan kadar asam urat didalam darah dengan menghambat xantin oksidase. Tujuan Penelitian adalah untuk mengetahui efek dari pemberian ekstrak daun rambutan untuk menurunkan kadar asam urat dan untuk menentukan dosis ekstrak yang paling efektif dalam menurunkan kadar asam urat. Metode Penelitian ini merupakan uji eksperimental (percobaan) untuk menguji efektivitas antihiperurisemia ekstrak etanol daun rambutan pada 25 ekor mencit (Galur Swiss Webster) jantan yang diobati dengan kalium oksonat dengan dosis 250 mg yang diinduksi asam urat selama 7 hari berturut-turut. Hasil dan Pembahasan Pada uji efek terapeutik untuk memantau penurunan kadar asam urat, hewan percobaan dibagi menjadi lima kelompok yaitu kelompok kontrol negatif (Na CMC 0,5%) , kontrol positif (allopurinol 100 mg) serta kelompok yang diberikan ekstrak dengan dosis pada setiap kelompok yaitu 20, 28, 36 mg/kgBB. Pantau penurunan kadar asam urat pada hari ke 7 dan 14. Hasil analisis menunjukkan bahwa data menggunakan uji levene test, shapiro wilk, Two-way anova dan post hoc test bahwa dosis ekstrak daun rambutan yang paling efekif menurunkan kadar asam urat mencit putih jantan adalah 36 mg/kgBB. Kesimpulan adalah dosis ekstrak daun rambutan yang memiliki efek menurunkan kadar asam urat pada mencit putih jantan paling efektif yaitu konsentrasi 36 mg/kg BB.
Co-Authors Dwi Intan Permata Sari RINA SE SITINDAON Sarah Hanifah Az-Zahra Anwar Sintya Merinda