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OVERVIEW PRESCRIBING WITH DUPLICATED NSAID THERAPY WITHOUT GASTRIC PROTECTIVE AGENTS AT A HOSPITAL IN INDONESIA Nurmesa, Adi; Rachman, Abu; Jannah, Wardatul
Jurnal Ilmiah Farmako Bahari Vol 15, No 2 (2024): Jurnal Ilmiah Farmako Bahari
Publisher : Faculty of Mathematic and Natural Science, Garut University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52434/jifb.v15i2.3179

Pain is a defence mechanism for the body that arises when the tissues in the body are being damaged. Pain therapy can be used in the form of NSAIDs. In prescribing NSAIDs, there is a risk of drug-related problems in the form of treatment duplication without gastroprotective. This study aims to determine the description of the type of duplication of NSAIDs without gastroprotective and explain pharmacist intervention efforts in reducing drug-related problems in prescribing NSAIDs. This retrospective observational study is conducted on all incoming prescriptions at the pharmacy satellite in March-June 2022 at one of the hospitals in Indonesia. The results of this study found 53 cases of duplication of NSAID therapy without gastroprotective from a total of 3,200 prescriptions, with the most duplication of NSAID therapy between Ibuprofen 400 mg and Mefenamic Acid 500 mg 24 cases. Pharmacist intervention in the form of clinical prescription screening is beneficial to avoid the risk of drug-related problems in prescribing NSAIDs.

RISK FACTORS FOR DUPLICATION OF NSAIDs WITHOUT GASTROPROTECTIVE IN ONE OF THE HOSPITALS IN INDONESIA Nurmesa, Adi; Jannah, Wardatul; Rachman, Abu; Wahyudi
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 3 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i3.1271

The use of dual NSAIDs without gastroprotective is one of the drug related problems that often occurs in hospitals, the purpose of giving dual NSAIDs is to increase the effectiveness of pain relief in reducing pain in patients. However, the use of dual NSAIDs without gastroprotective increases the risk of side effects on the gastrointestinal tract, kidneys, and cardiovascular system. This study aimed to examine the risk factors for duplication of NSAID therapy without gastroprotective in the outpatient pharmacy unit at a type C hospital in Banyuasin district. This analytical study used a cross-sectional research design to determine the influence of risk factors on the incidence of duplication of NSAIDs therapy without gastroprotective in the outpatient polyclinic. Data were analyzed using Pearson Chi Square analysis. The results of the bivariate analysis showed that older age, polypharmacy, and multipathology were factors associated with the incidence of NSAID duplication in outpatients with p values (OR) of 0.047 (1.101), 0.025 (2.63), 0.025 (2.63), and 0.025 (2.63), respectively. Keywords: Therapeutic duplications, Ibuprofen, Diclofenac, Gastroprotective agent

OVERVIEW PRESCRIBING WITH DUPLICATED NSAID THERAPY WITHOUT GASTRIC PROTECTIVE AGENTS AT A HOSPITAL IN INDONESIA Nurmesa, Adi; Rachman, Abu; Jannah, Wardatul
Jurnal Ilmiah Farmako Bahari Vol 15 No 2 (2024): Jurnal Ilmiah Farmako Bahari
Publisher : Faculty of Mathematic and Natural Science, Garut University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52434/jifb.v15i2.3179

Pain is a defence mechanism for the body that arises when the tissues in the body are being damaged. Pain therapy can be used in the form of NSAIDs. In prescribing NSAIDs, there is a risk of drug-related problems in the form of treatment duplication without gastroprotective. This study aims to determine the description of the type of duplication of NSAIDs without gastroprotective and explain pharmacist intervention efforts in reducing drug-related problems in prescribing NSAIDs. This retrospective observational study is conducted on all incoming prescriptions at the pharmacy satellite in March-June 2022 at one of the hospitals in Indonesia. The results of this study found 53 cases of duplication of NSAID therapy without gastroprotective from a total of 3,200 prescriptions, with the most duplication of NSAID therapy between Ibuprofen 400 mg and Mefenamic Acid 500 mg 24 cases. Pharmacist intervention in the form of clinical prescription screening is beneficial to avoid the risk of drug-related problems in prescribing NSAIDs.

Tingkat Pengetahuan dan Rasionalitas Swamedikasi Pasien Penyakit Gastritis di Apotek Kota Palembang Niza, Hairun; Rahayu, Kintan Putri; Soyata, Amelia; Afriliza, Dini; Rachman, Abu
Jurnal Ilmiah Farmako Bahari Vol 16 No 2 (2025): Jurnal Ilmiah Farmako Bahari
Publisher : Faculty of Mathematic and Natural Science, Garut University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52434/jifb.v16i2.41936

Masyarakat banyak melakukan swamedikasi dalam menangani keluhan atau gejala penyakit ringan. Dalam melakukan swamedikasi, penggunaan obatnya harus memenuhi kriteria rasional. Kurangnya pengetahuan tentang swamedikasi mengakibatkan terjadinya medication error. Gastritis merupakan salah satu dari penyakit yang dapat diobati secara swamedikasi. Penelitian ini bertujuan untuk mengetahui tingkat pengetahuan responden dan rasionalitas dalam penggunaan obat. Metode yang digunakan pada penelitian observasional deskriptif dengan metode survei cross sectional. Data diambil melalui pengisian kuesioner oleh responden yang melakukan swamedikasi Gastritis di 3 apotek Kota Palembang, yang masuk dalam kriteria inklusi. Jenis kuesioner yang digunakan adalah Guttman. Data diolah menggunakan uji chi-square. Hasil penelitian menyatakan tingkat pengetahuan pasien pada swamedikasi Gastritis berkategori Baik sebanyak 52,3% dan yang berkategori kurang baik sebanyak 47,7%. Mayoritas pasien sebanyak 59% melakukan swamedikasi secara tidak rasional dan 41% secara rasional. Hasil pengujian chi-square antara tingkat pengetahuan dan rasionalitas mendapat p value (,000) yang artinya terdapat hubungan. Tingkat pengetahuan terhadap sosiodemografi memiliki hubungan pada kategori jenis kelamin, pendidikan dan pekerjaan dengan p value <0,05. Namun tidak memiliki hubungan terhadap kategori usia karena p value >0,05. Berdasarkan hasil penelitian dapat disimpulkan tingkat pengetahuan pasien tergolong baik 52,3% dan rasionalitas penggunaan obat tergolong tidak tepat 59%.

Cognitive Function in Type 2 Diabetes Mellitus Patients Taking Metformin and Metformin-Sulfonylurea Rachman, Abu; Sauriasari, Rani; Syafhan, Nadia Farhanah; Prawiroharjo, Pukovisa; Risni, Hindun Wilda
Kesmas Vol. 17, No. 4
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

The most prescribed antidiabetic drugs in Indonesian primary health care are metformin or a combination of metformin and sulfonylurea. Studies on metformin have shown various impacts on cognitive decline in patients with type 2 diabetes mellitus, whereas sulfonylurea has been shown to reduce this impact. This study aimed to compare the impacts of metformin and metformin-sulfonylurea on cognitive function and determine what factors affected it. This cross-sectional study was conducted at Pasar Minggu Primary Health Care involving 142 type 2 diabetes mellitus patients taking metformin or metformin-sulfonylurea for > 6 months and aged > 36 years. Cognitive function was assessed using the validated Montreal Cognitive Assessment Indonesian version. The effects of metformin and metformin-sulfonylurea on cognitive decline showed no significant difference, even after controlling for covariates (aOR = 1.096; 95% CI = 0.523–2.297; p-value = 0.808). Multivariate analysis showed age (OR = 4.131; 95% CI = 1.271–13.428; p-value = 0.018) and education (OR = 2.746; 95% CI = 1.196–6.305; p-value = 0.017) affected cognitive function. Since a lower education and older age are likely to cause cognitive decline, health professionals are encouraged to work with public health experts to address these risk factors for cognitive function.

COST OF ILLNESS ANALYSIS OF EPILEPSY OUTPATIENTS USING VALPROIC ACID, PHENYTOIN AND CARBAMAZEPINE THERAPY IN HOSPITAL IN INDONESIA Nurmesa, Adi; Putra, Dimas Setyadi; Rachman, Abu; Wahyudi, Wahyudi
Usadha Journal of Pharmacy Vol. 3 No. 3 (2024): Agustus
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/ujp.v3i3.380

Epilepsy is a condition of the onset of attacks in the form of abnormal, irregular brain nerve cell movements, occurring repeatedly and causing temporary motor, sensory or mental function disorders. The treatment of epilepsy has costs that must be known, including direct medical costs, indirect medical costs, and indirect costs; this study aims to determine the cost of illness of epilepsy in one hospital in banyuasin regency with retrospective costing in outpatients. The research method used in this study is a cross-sectional study using patient medical record data and cost data taken from BPJS claims data and hospital rate patterns. This study uses the BPJS perspective and societal perspective, the cost data taken from the BPJS perspective is the result of BPJS claims according to the INACBGs. Package tariff and for the socital perspective the data taken is doctor consultation data, administrative costs, laboratory costs, drug costs and transportation costs and lost productivity costs carried out by interview method for 12 months. The results of this study indicate that the cost of epilepsy outpatients from a societal perspective is Rp.3,141,414 and for BPJS perspective is Rp.2,338,567.

PENYULUHAN SWAMEDIKASI OBAT BATUK PADA IBU-IBU RT.18 KELURAHAN TALANG JAMBE Niza, Hairun; Afriliza, Dini; Rachman, Abu
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 6 No. 1 (2025): Volume 6 No. 1 Tahun 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v6i1.39734

Swamedikasi merupakan suatu upaya pengobatan sendiri. Swamedikasi biasanya dilakukan untuk mengatasi keluhan dan penyakit ringan yang dialami banyak orang, seperti demam, nyeri, pusing, batuk, influenza, tukak lambung, cacingan, diare, penyakit kulit, dan lain-lain. Batuk merupakan salah satu penyakit ringan termasuk infeksi saluran pernapasan akut yang pengobatannya sebagian besar dilakukan sendiri (swamedikasi). Pengabdian kepada masyarakat ini bertujuan untuk memberikan edukasi kepada masyarakat tentang swamedikasi batuk dan pemilihan obat batuk kering serta batuk berdahak. Sehingga masyarakat dapat terhindar dari bahaya efek samping obat atau efek toksik obat, sehingga apabila penggunaan obat yang tepat telah dilakukan oleh masyarakat, maka peningkatan kesehatan masyarakat itu sendiri dapat terwujud. Metode kegiatan yang dilakukan adalah sosialisasi dan pembinaan sikap serta kesadaran masyarakat melalui penyebaran leaflet tentang “Swamedikasi Obat Batuk” kemudian melaksanakan pembinaan dalam bentuk ceramah, dan diskusi. Di akhir sesi penyuluhan dilakukan sesi tanya jawab dan diskusi tentang materi yang dijelaskan. Hasil penyuluhan menunjukkan bahwa pengetahuan masyarakat tentang pengobatan sendiri khususnya tentang obat batuk masih terbatas. Kemudian dilanjutkan dengan sesi tanya jawab di akhir sesi, hasil penyuluhan menunjukkan adanya peningkatan pengetahuan masyarakat tentang pengobatan sendiri obat batuk, jenis-jenis batuk, dan pemilihan pengobatan untuk batuk kering dan batuk berdahak.

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