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All Journal SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Martabe : Jurnal Pengabdian Kepada Masyarakat Jurnal Insan Farmasi Indonesia Journal of Fundamental and Applied Pharmaceutical Science Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Pengabdian Mandiri Jurnal Farmasi Sains dan Praktis Jurnal Vokasi Kesehatan Jurnal Pengabdian Masyarakat Bhinneka Borneo Journal of Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian Density Journal
Joko Priyanto Wibowo
Universitas Muhammadiyah Banjarmasin
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Control & Systems Engineering Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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Antibacterial and Antibiofilm Activity of the Extract and Fractions of Kelakai (Stenochlaena palustris (Burm.F) Bedd) against Methicillin-resistant Staphylococcus aureus Joko Priyanto Wibowo; Restu Dara Wewengkang; Medina Nurrahmah; Nurul Fajeriyati; Irfan Zamzani; Afif Pranaya Jati
Borneo Journal of Pharmacy Vol. 8 No. 4 (2025): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v8i4.8991

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) is a major concern in healthcare due to its resistance to antibiotics and ability to form biofilms. This study investigated the antibacterial and antibiofilm activity of the extract and fractions of kelakai (Stenochlaena palustris) leaves against MRSA. Phytochemical screening revealed the presence of alkaloids, flavonoids, steroids, tannins, and triterpenoids in S. palustris leaves. The ethanolic extract of S. palustris leaves exhibited dose-dependent antibacterial activity against MRSA at concentrations up to 500 ppm. Among the fractions, the n-hexane fraction exhibited antibacterial activity at 500 and 1000 ppm, while the methanolic fraction showed inhibition only at 1000 ppm. The ethyl acetate fraction did not show any inhibition. All fractions and extract demonstrated antibiofilm activity, with the n-hexane fraction exhibiting the strongest activity (91.33 ± 1.52%) at 125 ppm. The crude extract of S. palustris leaves showed the weakest antibiofilm activity (32.66 ± 8.14%). These findings suggest that S. palustris leaves contain compounds with antibacterial and antibiofilm properties against MRSA, with the n-hexane fraction being the most promising. Further studies are needed to isolate and characterize the active compounds responsible for these activities.
Edukasi pencegahan diare dan pembuatan hand sanitizer di panti asuhan Ar-Risalah Banjarmasin Ahmad Sazali; Evania Elianti Supar; Yuniarti Erisha Fauzi; Yolanda Yolanda; Risa Ahdyani; Joko Priyanto Wibowo; Irfan Zamzani
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 9, No 1 (2025): January
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v%vi%i.27134

Abstract

AbstrakBakteri menjadi satu penyebab terjadinya infeksi. Organ saluran pencernaan merupakan bagian yang sering terinfeksi. Escherichia coli beberapa diantaranya berada pada saluran pencernaan, namun yang bersifat patogen dapat menyebabkan diare. Tujuan kegiatan pengabdian masyarakat untuk meningkatkan pengetahuan terhadap pencegahan diare dan peningkatan ketrampilan pembuatan hand sanitizer bagi mitra di panti asuhan yayasan Ar-Risalah Banjarmasin. Metode yang diberikan berupa pendidikan kesehatan dengan rangkaian pemaparan materi mengenai bahaya dan pencegahan diare serta pelatihan pembuatan sedian gel hand sanitizer. Kegiatan ini diikuti orang warga panti asuhan Ar-Risalah sebanyak 15 orang pada 23 Maret 2024. Hasil kegiatan berupa tingkatan pengetahuan tentang bahaya dan pencegahan diare terdiri atas berpengetahuan yang baik sebanyak 6 orang (41%) dan berpengetahuan cukup sebanyak 6 orang (39%) serta berpengetahuan kurang sebanyak 3 orang (20%) pada peserta pengabdian masyarakat dan ketrampilan pembuatan sediaan hand sanitizer peserta mulai trampil. Produk sediaan gel hand sanitizer dapat dimanfaatkan dalam mencegah kasus diare dan mampu meningkatkan hidup sehat. Kata kunci: diare; hand sanitizer; panti asuhan Abstract Bacteria are one cause of infection. The organs of the digestive tract are the parts that are often infected. Some of Escherichia coli are located in the digestive tract, but those that are pathogenic can cause diarrhea. The purpose of community service activities is to increase knowledge about diarrhea prevention and improve hand sanitizer making skills for partners at the Ar-Risalah Banjarmasin foundation orphanage. The method provided was in the form of health education with a series of material presentations on the dangers and prevention of diarrhea as well as training in making hand sanitizer gel preparations. This activity was attended by 15 residents of the Ar-Risalah orphanage on March 23, 2024. The results of the activity in the form of a level of knowledge about the dangers and prevention of diarrhea consisted of 6 people (41%) who had good knowledge and 6 people (39%) who had sufficient knowledge and 3 people (20%) who had less knowledge in community service participants and the skills in making hand sanitizer preparations for participants began to be skilled. Hand sanitizer gel preparations can be used to prevent diarrhea cases and be able to improve healthy living. Keywords: diarrhea; hand sanitizer; orphanage
Transfer Teknologi Kesehatan Aplikasi Layanan Pengobatan Gratis MPKU Kapuas Daipadli Daipadli; Lukman Harun; Subhan Panji Cipta; Viony Tri Banowati; Siti Rahmaniah; Najwi Hasani; Nor Latifah; Joko Priyanto Wibowo
Jurnal Pengabdian Masyarakat Bhinneka Vol. 5 No. 1 (2026): September
Publisher : Bhinneka Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58266/jpmb.v5i1.1665

Abstract

Majelis Pembinaan Kesehatan Umum (MPKU) Muhammadiyah Kapuas menghadapi hambatan operasional layanan kesehatan di daerah terpencil akibat pengelolaan data manual, seperti tingginya waktu tunggu antrean, risiko kesalahan data, dan inefisiensi manajemen logistik obat. Pengabdian masyarakat ini bertujuan meningkatkan efektivitas, efisiensi, dan akuntabilitas operasional program pengobatan gratis melalui modernisasi sistem pelayanan berbasis Sistem Informasi Manajemen (SIM) MPKU. Kegiatan ini menggunakan pendekatan Participatory Action Research (PAR) melalui tahap persiapan, pelatihan (capacity building), dan evaluasi. Sasaran program meliputi 15 staf medis dan administratif serta 70 pasien penerima manfaat. Pengumpulan data dilakukan melalui observasi waktu, kuesioner System Usability Scale (SUS), kuesioner kepuasan, dan analisis dokumen logistik. Analisis data memanfaatkan statistik komparatif (Paired Sample t-Test), uji proporsi, dan analisis deskriptif.
STUDI PERKUATAN TANAH DASAR DENGAN CERUCUK GALAM PADA RUAS JALAN BANJARMASIN – BATAS KALTENG Irwandy Muzaidi; Wiwik Agustinaningsih; Joko Priyanto Wibowo
Density (Development Engineering of University) Journal Vol. 6 No. 1 (2023)
Publisher : Universitas Muhammadiyah Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35747/deuj.v6i1.843

Abstract

Transportasi jalan raya sangat berperan dalam perkembangan suatu daerah. Apalagi kondisi sekarang ini transportasi jalan raya sangat dibutuhkan sebagai penghubung dari suatau daerah kedaerah lainnya. Tanah memegang peranan yang sangat penting, yaitu sebagai pondasi pendukung untuk berbagai proyek konstruksi, serta sebagai pondasi pendukung untuk pembangunan gedung, jalan (subgrade). Tujuan yang diharapkan dari penelitian ini adalah mengetahui daya dukung tanah akibat adanya penggunaan cerucuk galam serta menghitung penurunannya yang terjadi. Penelitian ini bersifat eksperimental-laboratoris. Penelitian dilakukan dalam skala laboratorium dengan membuat benda uji sehingga didapatkan sifat fisi dan mekanis tanah. Dari hasil dan pembahasan yang telah dilakukan didapat kesimpulan bahwa daya dukung tanah dengan adanya perkuatan cerucuk galam dari sebelumnya 0,3504 t/m2 menjadi 6,95 t/m2. penurunan segera (immediate settlement) yang terjadi pada timbunan sebesar = ±3,2 cm.
Unlocking Antibiofilm Compounds of Tigarun (Crataeva magna (Lour.) DC.): A Metabolomic Insight via FTIR Spectroscopy Wibowo, Joko Priyanto; Lestari, Dwintha; Nor, Islan; Hasani, Najwi; Wewengkang, Restu Dara; Nurrahmah, Medina
Journal of Fundamental and Applied Pharmaceutical Science Vol. 7 No. 1 (2026): August
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/jfaps.v7i1.28123

Abstract

Antimicrobial resistance remains a major challenge in the treatment of bacterial infections worldwide, particularly because certain pathogenic bacteria can form biofilms that enhance antibiotic resistance. Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most clinically significant antibiotic-resistant bacteria, with biofilm formation contributing to persistent infections and reduced therapeutic efficacy. Therefore, the exploration of medicinal plants as alternative sources of antibiofilm agents has become increasingly important. This study aimed to evaluate the antibiofilm activity of three parts of Tigarun (Crataeva magna (Lour.) DC.), a native medicinal plant from Borneo, against MRSA and to investigate the potential metabolites associated with its activity through metabolomic analysis. Leaf, bark, and flower extracts of C. magna were obtained using ultrasound-assisted extraction. Antibiofilm activity against MRSA ATCC 33591 was evaluated using a spectrophotometric microplate assay. Metabolomic profiling was conducted using Fourier-transform infrared (FTIR) spectroscopy combined with multivariate statistical analysis to identify metabolite groups that may be responsible for the antibiofilm activity. The results demonstrated that the leaf and flower extracts exhibited strong antibiofilm activity against MRSA biofilms, with IC₅₀ values of 52.88 ± 5.77 µg/mL and 49.30 ± 5.23 µg/mL, respectively. In contrast, the bark extract showed weaker activity, with an IC₅₀ value exceeding 100 µg/mL. FTIR-based metabolomic analysis and multivariate modeling indicated that phenolic and flavonoid metabolites were strongly associated with antibiofilm activity. These findings suggest that C. magna, particularly its leaf and flower extracts, has promising antibiofilm potential against MRSA and may serve as a valuable natural resource for developing alternative antimicrobial agents targeting biofilm-associated bacterial infections.
Co-Authors Adinda Wulandari Afif Pranaya Jati Ahmad Sazali Akhmad Fadillah Mursyid Andi Suhendi Daipadli Daipadli Didik Setiawan Dwi Lestari Evania Elianti Supar Hadi, Ismanurrahman Hakim, Khoirul Usmanul Heni Lutfiyati, Heni Hidajah Rachmawati Indah Nurcahyani Irfan Zamzani Irfan Zamzani Irwandy Muzaidi Islan Nor Lestari, Dwintha Lukman Harun Medina Nurrahmah Mira Mira Mirajunnisa Najwi Hasani Noor Aida Noor Khalilati, Noor Nor Latifah Nor, Islan Nurrahmah, Medina Nurul Fajeriyati Paramitha, Dewi Setya Qadhy Kamil Al-Banjarie Restu Dara Wewengkang Ria Utami, Primanitha Risa Ahdyani Siti Rahmaniah Stevani Angelica Subhan Panji Cipta Vidya Azelia Sherlinda Viony Tri Banowati Wahid, Abdul Rahman Wewengkang, Restu Dara Wiwik Agustinaningsih Yolanda Yolanda Yuniarti Erisha Fauzi Zamzani, Irfan