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Aktivitas Antibakteri Ekstrak Metanol Daun Matenasi (Garcinia Sp.) Terhadap Staphylococcus Aureus dan Eschericia Coli Diani Mega Sari; Suci Fitriani Sammuli; Tesa Br. Napitupulu; Sri Warni
SEHATMAS: Jurnal Ilmiah Kesehatan Masyarakat Vol. 2 No. 1 (2023): Januari 2023
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/sehatmas.v2i1.1181

Abstract

Medicinal plants are very popular among the people of Indonesia as traditional medicinal ingredients. Traditional medicine is a means of supporting public health for generations, long before formal health services and modern medicines touched the layers of society. One of the medicinal plants which is efficacious as a medicine for diarrhea is matenasi leaf (Garcinia sp). Diarrhea is an infectious disease that often occurs in Indonesia due to Escherichia coli bacteria. This study aims to determine the antibacterial activity of methanol extract using the paper disc diffusion method which is dripped with 10 µl of the test solution using a micro pipette. The concentrations of the methanol extract used were 50%, 75%, and 100% compared to the positive control, namely 30 µl chloramphenicol solution. Matenasi leaves using methanol extract have strong antibacterial activity at a concentration of 100%. For Staphylococcus aureus bacteria with a concentration of 100% with a diameter of 22.67 mm (very strong category), Escherichia coli bacteria with a concentration of 100% with a diameter of 18.25 mm (strong category). The methanol extract of matenasi leaves has the potential as an antibacterial against Stapylococcus aureus and Escherichia coli bacteria.
Pengabdian Masyarakat Melalui Sosialisasi Prosedur Karantina Mandiri Di Puskesmas Tiban Baru Dan Masyarakat Sekitar Perumahan Mahasiswa Atau Mahasiswi Kota Batam Delladari Mayefis; Arie Vonikartika; Diani Mega Sari; Rury Trisa Utami
ARDHI : Jurnal Pengabdian Dalam Negri Vol. 1 No. 1 (2023): ARDHI : Jurnal Pengabdian Dalam Negri
Publisher : Asosiasi Riset Pendidikan Agama dan Filsafat Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/ardhi.v1i1.216

Abstract

Firstly, COVID-19 was reported in Indonesia on March 2, 2020, in several cases. The latest data on April 23 2020, there were 15,331 confirmed cases with 120 deaths. COVID-19 cases in Batam City have started to increase in the last week. As of April 30, there have been five positive cases of COVID-19, and one person died. Tiban Baru is one of the area in the Batam City. Many people still do not understand self-isolation, especially when they have a history of contact with positive cases, have just returned or traveled outside the city, and have symptoms similar to COVID-19. Furthermore, they are still in contact with other family members. This will certainly expand the expansion of case transmission in households. This activities partner up with a village headman of Tiban Baru. The solution to the problem is education to the public about self-isolation for people in the assesment in handling COVID-19. Educations provided through the media of leaflets and masks donations to people affected by COVID-19. The purpose of this activity is to increase public knowledge about self-isolation efforts if they have symptoms similar to COVID-19 or contact with COVID-19 cases and improve hygiene in the community as an effort to prevent transmission of COVID-19
Analisis Kandungan Asam Retinoat Pada Krim Anti Jerawat Di Toko Kosmetik X Pasar Jodoh Diani Mega Sari; Eka Febriyanti; Ghalib Syukrillah Syahputra; Annisa Laili Oktaviyani
SEHATMAS: Jurnal Ilmiah Kesehatan Masyarakat Vol. 3 No. 1 (2024): Januari 2024
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/sehatmas.v3i1.3002

Abstract

Growth from adolescence to adulthood is a transition that causes many hormonal changes, both physical, psychological and social. This change will cause health problems, one of which is on the face, namely Acne vulgaris (AV). Retinoic acid is one of the chemicals that is prohibited for use because it can cause dry skin, burning, teratogenicity (fetal defects)0and skin cancer. The aim of this research was to find out whether the acne cream in the cosmetic shop x Pasar Jodoh contained retinoic acid, and to determine the levels of retinoic acid in the samples. There were 10 acne cream samples studied. The qualitative test of retinoic acid uses the thin layer chromatography (TLC) method observed under UV 254 light. And the quantitative test uses the UV-Vis Spectrophotometry method. Spectrophotometric determination of retinoic acid levels at a wavelength of 340 nm. The results0obtained by the thin layer chromatography (TLC) method were that sample B was positive for retinoic acid and the results from the UV-Vis spectrophotometry0method were 0.0005%.
Formulation And Physical Properties Evaluation Of Beach Morning Glory (Ipomoea Pescaprae) Leaves Ointment Meddo Lorenza Garnida; Delladari Mayefis; Habibie Deswilyaz; Mega Sari, Diani; Arie Vonikartika
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 8 No. 1 (2023)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v8i1.30572

Abstract

Background: Sea kangkung is one of the plants used as traditional medicine which is widely used as a topical medicine, one of which is to treat jellyfish stings and ulcers. This study aims to determine how to formulate ointment preparations from sea kangkung extract and to test the physical properties of sea kangkung preparations. Methods: Sea kangkung leaves were extracted using the maceration method using methanol as a solvent and then made preparations in the form of an ointment using concentration variations, namely (F1) - , (F2) 1 % , (F3), 3 % (F4), 5 % (F5) 10 %. Furthermore, the physical stability test of the ointment was carried out, namely the Cycling Test including organoleptic test, homogeneity test, pH test and spreadability. Results: The results obtained that sea kangkung extract ointment has a fairly good stability based on the stability test of the third formula, which is the most stable preparation.
Gummy Mandjah (Honey, Tamarind, Red Ginger) on Emesis in Pregnant Women Huzaima, Huzaima; Sari, Diani Mega; Razak , Rifka Atika
Biomedical Journal of Indonesia Vol. 11 No. 1 (2025): Vol 11, No 1, 2025
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v11i1.221

Abstract

Introduction. One of the discomforts that mothers frequently experience during the start of pregnancy is emesis gravidarum, which is characterized by nausea and vomiting. The welfare of the mother and child will be impacted if emesis episodes are not handled right away. Herbal remedies like red ginger, tamarind, and honey can help people stay healthy. The purpose of this study is to examine how “Gummy Mandjah” can help pregnant women experience less nausea. Methods. This study used a pre-experimental research design, one group pretest posttest. Giving gummy made from honey, tamarind, and red ginger to 20 pregnant women who met the inclusion criteria, sampling technique using simple random sampling, Gummy was given for 14 days with a dose of 2 times a day and then assessed using the PUQE score. Results. The results obtained showed that there was a decrease in the frequency of emesis after consuming gummy with an average difference of 0.60. Data analysis used a paired sample t-test and showed that there was an effect of giving gummy on reducing emesis with a p-value of 0.001 < 0.05. Conclusion. Honey, tamarind, and ginger can be an option to overcome nausea and vomiting in pregnant women. These ingredients are easy to obtain, practical to process, and have minimal side effects. With gummy innovations or other forms, it can make it easier for pregnant women to consume them and reduce the dominant smell and taste of each ingredient that can trigger mothers not to want to consume them.
Penyuluhan Medication Safety Amelia, Ayu; Yunaspi, Rakhmi Febrina; Sammulia, Suci Fitriani; Rachmayanti, Aprilya Sri; Meilanda, Rastria; Febriyanti, Eka; Sari, Diani Mega; Suhaera, Suhaera; Syukrillah, Ghalib; Rushd, Ibnu
Jurnal Pengabdian Masyarakat Bangsa Vol. 2 No. 12 (2025): Februari
Publisher : Amirul Bangun Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59837/jpmba.v2i12.2067

Abstract

Kesalahan medikasi merupakan salah satu penyebab utama insiden keselamatan pasien di fasilitas kesehatan dan dapat berdampak serius, seperti komplikasi kesehatan hingga kematian. Penyuluhan mengenai medication safety dilakukan di RS Harapan Bunda, Kota Batam, untuk meningkatkan pemahaman tenaga medis terhadap penggunaan obat yang aman dan efektif. Kegiatan ini mencakup pemaparan materi, diskusi kelompok, demonstrasi praktik, serta kuis interaktif untuk mengukur pemahaman peserta. Hasil evaluasi menunjukkan peningkatan pengetahuan tenaga medis mengenai penyebab, risiko, dan strategi pencegahan medication errors, seperti penerapan prosedur double-checking dan pemanfaatan teknologi dalam peresepan obat. Edukasi berbasis bukti yang interaktif terbukti efektif dalam meningkatkan kesadaran serta penerapan prinsip medication safety dalam praktik klinis.
UJI ANTIBAKTERI EKSTRAK BATANG GAHARU (Aquilaria malaccensis) BERBASIS KOLIN KLORIDA:ASAM SITRAT TERHADAP Bacillus cereus dan Shigella dysenteriae Hasan, Nahrul; Marlina, Sri; Amelia, Ayu; Syahputra, Ghalib Syukrillah; Sari, Diani Mega
Jurnal Buana Farma Vol. 5 No. 2 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i2.1396

Abstract

Infections caused by Bacillus cereus and Shigella dysenteriae are serious health problems as they can lead to gastrointestinal disorders and contribute to the emergence of antibiotic resistance. One potential strategy to overcome this challenge is the discovery of new antibacterial agents derived from natural sources, such as agarwood (Aquilaria malaccensis). This study aimed to evaluate the antibacterial activity of gaharu stem extract using a Natural Deep Eutectic Solvent (NADES) composed of choline chloride and citric acid through the Ultrasound Assisted Extraction (UAE) method. The antibacterial assay was performed using the disc diffusion method with various NADES ratios (1:1, 2:1, 1:2, 1:3, 1:4, and 4:1 g/g), with chloramphenicol as the positive control and 10% DMSO as the negative control. The results indicated that the NADES extract with a 1:4 g/g ratio produced the largest inhibition zones against Bacillus cereus and Shigella dysenteriae. Moreover, the Minimum Inhibitory Concentration (MIC) test showed that the 1:4 NADES extract effectively inhibited bacterial growth at a concentration of 30%. These findings suggest that gaharu stem extract prepared with NADES is a promising, eco-friendly, and potent antibacterial agent.
KENDALA RETENSI TERAPI ANTIRETROVIRAL (ARV) PADA PASIEN HIV/AIDS DI RSUD DR MOEWARDI (RSDM) SURAKARTA JAWA TENGAH Febriyanti, Eka; Sari, Diani Mega; Syahputra, Ghalib Syukrillah; Hasan, Nahrul; Amelia, Ayu; Meilanda, Rastria
Jurnal Farmasi Klinik dan Sains Vol 4, No 1 (2024): Jurnal Farmasi Klinik dan Sains
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Muhammadiyah Gombong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26753/jfks.v4i1.1365

Abstract

Terapi Antiretroviral (ARV) bertujuan untuk mengurangi risiko penularan HIV/AIDS, menghambat perburukan infeksi oportunistik, meningkatkan kualitas hidup Orang DenganHIV/AIDS (ODHA) dengan menurunkan jumlah viral load dan meningkatkan jumlah CD4. Kunci keberhasilan terapi ARV adalah mempertahankan retensi. Lost To Follow Up (LTFU) dan kegagalan pengobatan menjadi kendala bagi ODHA dalam mencapai keberhasilan pengobatan ARV. Penelitian ini bertujuan untuk mengetahui prediktor hambatan mendapatkan retensi pengobatan ARV. Penelitian ini menggunakan rancangan case control dengan jumlah sampel 100 responden. Analisis data dilakukan dengan menggunakan metode chi-square. Hasil analisis bivariat, prediktor buruknya retensi berdasarkan persepsi pasien terhadap hambatan menjalani terapi ARV adalah kendala biaya transportasi (p=0.002; COR=8.34), kendala jarak perjalanan ke RSDM (p=0.002; COR=5.06), hambatan kesibukan lainnya (p=<0.001; COR=6,64), memiliki Pengawas Menelan Obat (p=0.003; COR=6.64), mengungkapkan status ODHA kepada orang lain (p=0.004; COR= 12.25), dan stigma (p=<0.001; COR= 12,3). Berdasarkan hasil uji multivariat persepsi pasien terhadap hambatan dalam menjalankan terapi ARV yang paling berdampak pada buruknya retensi terapi adalah mengungkapkan status ODHA kepada orang lain (AOR=13.1; p=0.042).
EDUKASI PENCEGAHAN PENULARAN COVID-19 MELALUI PENYULUHAN, PEMBAGIAN MASKER, VITAMIN, DAN HAND SANITIZER DI PERUMAHAN TAMAN SARI HIJAU KOTA BATAM Mayefis, Delladari; Utam, Rury Trisa; Sari, Diani Mega; Ghiffari, Habibie Deswilyas; Budiasih, Sri
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 5 No. 1 (2024): Volume 5 No 1 Tahun 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v5i1.24588

Abstract

Pencegahan penularan covid-19 sudah banyak jenis himbauan patuh terhadap protocol kesehatan seperti rajin mencuci tangan menggunakan sabun, meenggunakan masker saat keluar rumah serta menerapkan physical distancing melalui media cetak maupun media social akan tetapi banyak sekali masyarakat yang belum memahami dan mempraktekannya sehingga masyarakat belum patuh dalam pencegahan covid-19. Hal ini lah yang mendorong dan memotivasi tim untuk melalukan edukasi melalui penyuluhan kepada masyarakat dengan tujuan untuk megedukasi tentang langkah- langkah pencegahan dan penularan covid-19, penggunaan masker dan cara mencuci tangan yang benar. Metode yang digunakan adalah, membuat hand sanitizer, menyiapkan 1 paket masker, vitamin dan hand sanitizer, edukasi pencegahan penularan covid di Masjid Ar-Rahmah perumahan Taman Sari Hijau. Hasil Pengabdian ini adalah masyarakat yang hadir di edukasi ini berjumlah 37 orang yang di laksanakan di masjid Ar-Rahmah perumahan Taman Sari Hijau. Masyarakat sangat antusias dengan edukasi ini. Dengan antusias tersebut meningkatkan pengetahuan dan kepatuhan, dan juga sangat senang karena pemberian 1 paktet masker, vitamin dan hand sanitizer.
FORMULASI DAN UJI EVALUASI PASTA GIGI CANGKANG TELUR BEBEK YANG MENGANDUNG KALSIUM KARBONAT DENGAN VARIASI KONSENTRASI XANTHAN GUM Ghiffari, Habibie Deswilyaz; Fitrya, Dessy; Sari, Diani Mega; Rushd, Ibnu
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 11 No. 2 (2025): Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v11i2.963

Abstract

Duck egg shells are an organic waste that is rich in calcium carbonate (CaCO?) and has the potential to be used as a natural abrasive in toothpaste preparations. This research aims to formulate toothpaste using duck eggshell powder as a source of calcium carbonate and evaluate the effect of varying concentrations of xanthan gum as a thickening agent on the physical quality of the resulting toothpaste. This research is experimental. Formulations are made with varying concentrations of xanthan gum, namely 0.5%, 1%, 1.5% and 2%. Evaluation of the preparation includes organoleptic tests, homogeneity, pH, viscosity, cycling test, stress test, long-term stability, and foam tests which are analyzed descriptively. The research results showed that all formulas produced toothpaste that met organoleptic, homogeneity and pH requirements (4.5–10.5). Increasing the concentration of xanthan gum affects viscosity. The formula with a xanthan gum concentration of 2% had the highest viscosity, while the formula with a concentration of 0.5% showed a lower viscosity. The foam test showed that the four formulas were able to produce foam with sufficient volume. In conclusion, formula 2 is a good, stable formula, and has the potential to be developed as a duck egg shell toothpaste preparation.