Article Per Year (5 Year)
p-Index From 2020 - 2025
0.444
P-Index
This Author published in this journals
All Journal Jurnal Buana Farma Jurnal Farmasi Klinik dan Sains
GHALIB SYUKRILLAH SYAHPUTRA, GHALIB SYUKRILLAH
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
UJI ANTIBAKTERI EKSTRAK BATANG GAHARU (Aquilaria malaccensis) BERBASIS KOLIN KLORIDA:ASAM SITRAT TERHADAP Bacillus cereus dan Shigella dysenteriae Hasan, Nahrul; Marlina, Sri; Amelia, Ayu; Syahputra, Ghalib Syukrillah; Sari, Diani Mega
Jurnal Buana Farma Vol. 5 No. 2 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i2.1396

Abstract

Infections caused by Bacillus cereus and Shigella dysenteriae are serious health problems as they can lead to gastrointestinal disorders and contribute to the emergence of antibiotic resistance. One potential strategy to overcome this challenge is the discovery of new antibacterial agents derived from natural sources, such as agarwood (Aquilaria malaccensis). This study aimed to evaluate the antibacterial activity of gaharu stem extract using a Natural Deep Eutectic Solvent (NADES) composed of choline chloride and citric acid through the Ultrasound Assisted Extraction (UAE) method. The antibacterial assay was performed using the disc diffusion method with various NADES ratios (1:1, 2:1, 1:2, 1:3, 1:4, and 4:1 g/g), with chloramphenicol as the positive control and 10% DMSO as the negative control. The results indicated that the NADES extract with a 1:4 g/g ratio produced the largest inhibition zones against Bacillus cereus and Shigella dysenteriae. Moreover, the Minimum Inhibitory Concentration (MIC) test showed that the 1:4 NADES extract effectively inhibited bacterial growth at a concentration of 30%. These findings suggest that gaharu stem extract prepared with NADES is a promising, eco-friendly, and potent antibacterial agent.
KENDALA RETENSI TERAPI ANTIRETROVIRAL (ARV) PADA PASIEN HIV/AIDS DI RSUD DR MOEWARDI (RSDM) SURAKARTA JAWA TENGAH Febriyanti, Eka; Sari, Diani Mega; Syahputra, Ghalib Syukrillah; Hasan, Nahrul; Amelia, Ayu; Meilanda, Rastria
Jurnal Farmasi Klinik dan Sains Vol 4, No 1 (2024): Jurnal Farmasi Klinik dan Sains
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Muhammadiyah Gombong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26753/jfks.v4i1.1365

Abstract

Terapi Antiretroviral (ARV) bertujuan untuk mengurangi risiko penularan HIV/AIDS, menghambat perburukan infeksi oportunistik, meningkatkan kualitas hidup Orang DenganHIV/AIDS (ODHA) dengan menurunkan jumlah viral load dan meningkatkan jumlah CD4. Kunci keberhasilan terapi ARV adalah mempertahankan retensi. Lost To Follow Up (LTFU) dan kegagalan pengobatan menjadi kendala bagi ODHA dalam mencapai keberhasilan pengobatan ARV. Penelitian ini bertujuan untuk mengetahui prediktor hambatan mendapatkan retensi pengobatan ARV. Penelitian ini menggunakan rancangan case control dengan jumlah sampel 100 responden. Analisis data dilakukan dengan menggunakan metode chi-square. Hasil analisis bivariat, prediktor buruknya retensi berdasarkan persepsi pasien terhadap hambatan menjalani terapi ARV adalah kendala biaya transportasi (p=0.002; COR=8.34), kendala jarak perjalanan ke RSDM (p=0.002; COR=5.06), hambatan kesibukan lainnya (p=<0.001; COR=6,64), memiliki Pengawas Menelan Obat (p=0.003; COR=6.64), mengungkapkan status ODHA kepada orang lain (p=0.004; COR= 12.25), dan stigma (p=<0.001; COR= 12,3). Berdasarkan hasil uji multivariat persepsi pasien terhadap hambatan dalam menjalankan terapi ARV yang paling berdampak pada buruknya retensi terapi adalah mengungkapkan status ODHA kepada orang lain (AOR=13.1; p=0.042).
Co-Authors Amelia, Ayu Hasan, Nahrul Meilanda, Rastria Nurwijayanti Sari, Diani Mega Sri Marlina, Sri