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Effects of Passiflora edulis Juice on Blood Pressure Among Patients with Hypertension: A Randomized Double-Blind Placebo-Controlled Trial Zahroh, Roihatul; Rahmawati, Ita; Gustomi, Mono Pratiko
Jurnal Pendidikan Keperawatan Indonesia Vol 12, No 1 (2026): Volume 12, Nomor 1, Juni 2026
Publisher : Universitas Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17509/jpki.v12i1.96756

Abstract

Introduction: Hypertension remains a major global public health challenge and a leading risk factor for cardiovascular morbidity and mortality. In addition to pharmacological therapy, dietary and natural product-based interventions have gained increasing attention as complementary strategies for blood pressure control. Passiflora edulis (passion fruit) contains bioactive compounds with potential antihypertensive properties; however, clinical evidence supporting its effectiveness remains limited. Objective: This study aimed to examine the effect of Passiflora edulis juice consumption on systolic and diastolic blood pressure among patients with hypertension. Methods: A randomized, double-blind, placebo-controlled trial was conducted among hypertensive patients attending an outpatient clinic in Indonesia. Participants were randomly assigned to receive either Passiflora edulis juice or a placebo beverage daily for a predefined intervention period. Systolic and diastolic blood pressure were measured at baseline and follow-up using standardized procedures. Data were analyzed using linear mixed-effects models to assess changes in blood pressure over time between groups, adjusting for relevant baseline covariates. All analyses followed the intention-to-treat principle. Results: Participants in the Passiflora edulis juice group demonstrated a significant reduction in both systolic and diastolic blood pressure compared with the placebo group over the intervention period. The group × time interaction effect was statistically significant (p 0.05), indicating greater blood pressure reduction among participants who consumed Passiflora edulis juice. No serious adverse events related to the intervention were reported. Conclusion: Daily consumption of Passiflora edulis juice was effective in reducing systolic and diastolic blood pressure among hypertensive patients. These findings suggest that Passiflora edulis juice may serve as a safe and beneficial complementary dietary intervention for hypertension management. Further large-scale and long-term studies are recommended to confirm these findings and explore underlying mechanisms.
A mixed-methods study of pregnancy-centered antenatal care strategies for stunting prevention in Jepara Regency Rahmawati, Ita; Zahro, Roihatul; Rosita, Devi
JNKI (Jurnal Ners dan Kebidanan Indonesia) (Indonesian Journal of Nursing and Midwifery) Vol. 14 No. 3 (2026)
Publisher : Alma Ata University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21927/jnki.2026.14(3).426-439

Abstract

Background: Stunting remains a major public health challenge rooted in the prenatal period. Although antenatal care (ANC) coverage in Indonesia is high, gaps in ANC quality, nutrition counseling, and risk-responsive care limit its effectiveness for stunting prevention.Objectives: This study examined pregnancy-centered ANC strategies for stunting prevention in Jepara Regency using a mixed-methods approach integrating quantitative and qualitative findings.Methods: An explanatory sequential mixed-methods design was applied. The quantitative phase involved a cross-sectional survey of 212 pregnant women receiving routine ANC. ANC quality was assessed using the Content-Qualified Antenatal Care (ANCq) indicator, dietary diversity using the Minimum Dietary Diversity for Women (MDD-W), and stunting prevention knowledge and practices through structured questionnaires. Multivariable generalized linear models identified predictors of stunting prevention practices. The qualitative phase included in-depth interviews with 24 purposively selected pregnant women. Reflexive thematic analysis and narrative integration were conducted.Results: The mean ANCq score was 7.1 ± 1.8, indicating moderate ANC adequacy, while only 46.2% of participants achieved minimum dietary diversity (MDD-W ≥5). Higher ANCq scores (β = 2.84; p < 0.001), adequate dietary diversity (β = 5.96; p < 0.001), maternal education, and partner support were significantly associated with stronger stunting prevention practices. Qualitative findings revealed limited understanding of stunting prevention despite regular ANC attendance, a knowledge–practice gap caused by economic and pregnancy-related barriers, and the important role of family and health-system support.Conclusions: Pregnancy-centered stunting prevention is strongly influenced by ANC quality, dietary diversity, education, and partner support. Strengthening risk-responsive ANC and practical nutrition counseling may improve early stunting prevention outcomes.