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All Journal Biology, Medicine, & Natural Product Chemistry Jurnal Ilmu Kefarmasian Indonesia Jurnal Pengabdian Masyarakat Nusantara Pengabdian Kampus: Jurnal Informasi Kegiatan Pengabdian Pada Masyarakat TRANSPUBLIKA INTERNATIONAL RESEARCH IN EXACT SCIENCES (TIRES) Health Research Journal of Indonesia Media Kesehatan Politeknik Kesehatan Makassar Barigas: Jurnal Riset Mahasiswa
Angeline Novia Toemon, Angeline Novia
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Economics, Econometrics & Finance Environmental Science Health Professions Immunology & microbiology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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The Effects Of Kelakai Leaf Infusion Kalakai (Stenochlaena palustris (Burm.F) Bedd) On The Levels of AST and ALT Enzymes in Wistar White Rats Induced with CCl4 Salsabila, Ivah; Carmelita, Austin Bertilova; Shinta, Herlina Eka; Toemon, Angeline Novia; Praja, Rian Ka
Barigas: Jurnal Riset Mahasiswa Vol. 3 No. 2 (2025): Barigas: Jurnal Riset Mahasiswa
Publisher : Fakultas Kedokteran Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/barigas.v3i2.12011

Abstract

The liver plays a crucial role in the body, including protein synthesis, bile secretion, metabolism, and xenobiotic excretion, making it susceptible to damage from exposure to toxic substances. Carbon tetrachloride (CCl4) is a free radical known to cause liver injury. Abundant in Kalimantan, kelakai contains flavonoids, alkaloids, steroids, and tannins, suggesting its metabolites may have hepatoprotective potential. This study aimed to assess the antioxidant content of kelakai leaf infusion for potential protection CCl4-induced liver damage. Kelakai leaves (Stenochlaena palustris (Burm.F) Bedd). were infused at a 20% concentration, then divided into three different doses: P1 (300 mg/kgBW), P2 (400 mg/kgBW) and P3 (5—mg/kgBW). The 14-day study evaluated whether kelakai leaf infusion could prevent the elevation of AST dan ALT enzyme ativities. The results indicated increased levels of AST dab AKT enzymes in each treatment group. Though the statistical analisis showed non-significant differences.
Health education for preventing flour albus with personal hygiene practices of reproductive organs of female students in MAN Palangka Raya WIDIARTI, ASTRI; Arifin, Syamsul; Lestarisa, Trilianty; Putra S, Ravenalla Abdurrahman Al Hakim Sampurna; Mutiasari, Dian; Widodo, Tri; Veronica, Anna Marthea; Toemon, Angeline Novia; Inarae, Gabriella
Jurnal Pengabdian Kampus Vol 10 No 2 (2023): Jurnal Pengabdian Kampus
Publisher : LPPM Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52850/jpmupr.v10i2.11388

Abstract

Flour albus is a lot happening to female teenagers, which caused by lack of knowledge about the behavior of personal hygiene reproductive organs that are very influential in the occurrence of flour albus. Women who have less knowledge about the hygiene of reproductive organs will have an impact on the health of their reproductive organs because knowledge is a determining factor in maintaining the hygiene of reproductive organs, especially in the genitals. Health promotion with topics regarding personal hygiene reproductives organs and flour albus in MAN Palangka Raya city has long not have been done, therefore, health education on flour albus prevention needs to be given. The goal of giving students a health education is to improve knowledge and information related to the prevention of flour albus with the application of personal hygiene organs in the school students of MAN Palangka Raya City. A health education activity carried out in the high school of man city roadblocks.The activities carried out are the educational delivery of flour albus as well as the prevention of personal hygiene.After that, a Q&A session performed between the students and the activity team and followed by a Q&A session as well as a quiz gift. Students who participate in this activity experience improved knowledge of flour albus prevention with the application of personal hygiene practices of reproductive organs, as shown by an average increase in post test results, this is from the pre-test with an average of 5.92 to 7.12 when the post-test performed. Similar activities need to be carried out regularly to students of the MAN Palangka Raya City, that they can apply proper personal hygiene of reproductive organs in preventing flour albus.
Hubungan Rinitis Alergi Dengan Kejadian Sinusitis Di Rsud Dr Doris Sylvanus Toemon, Angeline Novia; Hasan, Muhamad Umar Muhtar; Jabal, Arif Rahman; Teresa, Astrid; Praja, Rian Ka
Media Kesehatan Politeknik Kesehatan Makassar Vol 19 No 1 (2024): Media Kesehatan
Publisher : Direktorat Politeknik Kesehatan Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/medkes.v19i1.402

Abstract

Sinusitis is an inflammation of the paranasal sinus mucosa and is one of the world's health problems and is often found in medical practice. The National Health Interview survey in 2012, found that 12% of the total sample of 34,525 adults experienced sinusitis. Allergic rhinitis is one of the factors causing sinusitis due to bacterial infection of the sinus tract due to blockage of the sinus ostium and mucus that cannot be drained due to allergic reactions. This study aims to analyze the relationship between allergic rhinitis and the incidence of sinusitis in patients at RSUD dr Doris Sylvanus Palangka Raya. This research is an analytical observational study with a cross section study design conducted at RSUD dr Doris Sylvanus Palangka Raya. The subjects in this study were patients with a history of allergic rhinitis and sinusitis for the period 2021-2023 who met the inclusion and exclusion criteria. There were 271 research samples where the statistical test showed a p value = 0.000 and OR = 0.092. Allergic rhinitis has an association with sinusitis and allergic rhinitis has a chance of developing sinusitis.
Hubungan Tingkat Pengetahuan dan Dukungan Caregiver Terhadap Kepatuhan Rehabilitasi Pasien Stroke di RSUD Palangka Raya Sihotang, Merlin Romayana; Surbakti, Ranintha Br; Saritani, Ayunda Tamara Barito; Toemon, Angeline Novia; Astoeti, Dileli Dharma
Health Research Journal of Indonesia Vol 4 No 1 (2025): Health Research Journal of Indonesia
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/hrji.v4i1.868

Abstract

Pendahuluan: Stroke merupakan penyakit penyebab utama kematian dan kecacatan di dunia, termasuk di Indonesia. Pasien stroke sering mengalami gangguan fungsi tubuh sehingga membutuhkan rehabilitasi medik jangka panjang. Keberhasilan rehabilitasi sangat bergantung pada kepatuhan pasien dalam menjalani terapi, namun terkadang tingkat kepatuhan dalam menjalani terapi masih rendah. Peran caregiver dalam memberi dukungan maupun pengetahuan tentang perawatan stroke sangat penting untuk meningkatkan kepatuhan pasien terhadap program rehabilitasi medik.  Tujuan: Tujuan penelitian ini adalah untuk mengetahui hubungan antara tingkat pengetahuan dan dukungan caregiver terhadap kepatuhan rehabilitasi medik pasien stroke. Metode: Penelitian ini bersifat observasional analitik dengan pendekatan Cross Sectional. Jumlah sampel penelitian sebanyak 33 responden caregiver pasien stroke yang pernah melakukan rehabilitasi di RSUD Palangka Raya. Instrumen penelitian menggunakan kuesioner tingkat pengetahuan, dukungan caregiver, dan kepatuhan rehabilitasi medik.  Analisis data dilakukan dengan uji korelasi Somers’D. Hasil: Hasil uji korelasi Somers’D untuk korelasi antara tingkat pengetahuan dengan kepatuhan rehabilitasi medik menunjukkan nilai p = 0,423 (p>0,05). Sedangkan, untuk hubungan dukungan caregiver dengan kepatuhan rehabilitasi medik menunjukkan nilai p = 0,040 (p<0,05). Simpulan: Dari hasil analisis data ini, disimpulkan bahwa tidak terdapat hubungan yang signifikan antara tingkat pengetahuan caregiver dengan kepatuhan rehabilitasi medik pasien stroke. Namun, terdapat hubungan yang signifikan antara dukungan caregiver dengan kepatuhan rehabilitasi medik pasien stroke.
Evaluation of the combination patch of betel leaf extract (Piper sp.) - ultrasonic assisted extraction as a transdermal delivery system on fibroblast cell formation and collagen density Valencia, Regina; Trinovita, Elsa; Shinta, Herlina Eka; Toemon, Angeline Novia; Ysrafil, Ysrafil
JURNAL ILMU KEFARMASIAN INDONESIA Vol. 23 No. 1 (2025): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v23i2.1687

Abstract

The combination of red betel (Piper crocatum) and green betel (Piper betle L.) leaves is believed to act synergistically in enhancing wound healing. Transdermal patches offer advantages over conventional topical forms due to their sustained drug release, ease of application, and prolonged therapeutic effect. This study evaluated the histopathological effects of a combination patch containing betel leaf extracts for incision wound treatment in Wistar rats. The studies used an true experimental post-test-only control group design, five groups were tested: a blank patch (K−), a povidone-iodine patch (K+), and combination extract patches at concentrations of 7.5% (K1), 15% (K2), and 30% (K3), applied over 14 days with six animals per group. Patch characteristics were assessed through organoleptic tests, thickness, weight uniformity, folding endurance, and pH, while wound healing was evaluated through histological analysis of fibroblast cell counts and collagen density. Statistical analysis was conducted using the Kruskal-Wallis test followed by Mann-Whitney post-hoc tests. The 30% combination patch (K3) showed the most significant healing effect, with fibroblast counts exceeding 50 cells and dense collagen formation scoring +3. These results indicate that a transdermal patch combining Piper crocatum and Piper betle L. extracts effectively promotes wound healing by enhancing fibroblast proliferation and collagen synthesis.
Co-Authors Ahmad, Farah Fauziah Radhiyatulqalbi Arif Rahman Jabal Astoeti, Dileli Dharma Auliyah, Mayasin Tania Austin Bertilova Carmelita, Austin Bertilova Balyas , Abi Bakring Balyas, Abi Bakring Br Surbakti, Ranintha Dian Mutiasari, Dian Dileli Dharma Astoeti Elsa Trinovita Hanasia, Hanasia Hasan, Muhamad Umar Muhtar Herlina Eka Shinta Inarae, Gabriella Kesuma, I Putu Gede Candra Kurniawan, Mutiara Lestarisa, Trilianty Natalia Sri Martani Panueh, Jovanka Mangium Wijayanti Parhusip, Luther Putra S, Ravenalla Abdurrahman Al Hakim Sampurna Ranintha br Surbakti Rian Ka Praja Salsabila, Ivah Salsabilah, Alfisa Fitri Saritani, Ayunda Tamara Barito Sihotang, Merlin Romayana Sitompul, Sanggap Indra Steffany Angelina Monica Syamsul Arifin Teresa, Astrid Tjahjono, Herry Tori, Marthin Tri Widodo Turnip, Oktaviani Naulita Valencia, Regina Veronica, Anna Marthea Widiarti, Astri Ysrafil, Ysrafil