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All Journal Jurnal Ilmu Pertanian Indonesia Jurnal Riset Kesehatan Biology, Medicine, & Natural Product Chemistry Majalah Obat Tradisional Jurnal Surya Medika Jurnal Ilmu Kedokteran dan Kesehatan PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Ilmu Kefarmasian Indonesia Journal of Experimental and Clinical Pharmacy (JECP) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Pengabdian Ilung (Inovasi Lahan Basah Unggul) JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Pharmaceutical Sciences and Research (PSR) Jurnal Farmasi Indonesia Barigas: Jurnal Riset Mahasiswa
Elsa Trinovita
Department Of Pharmacotherapy, Faculty Of Medicine, University Of Palangka Raya, Palangka Raya, Central Kalimantan
Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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Korelasi Usia Metabolik terhadap Indeks Massa Tubuh Ni Nyoman Sri Yuliani; Elsa Trinovita
Jurnal Surya Medika (JSM) Vol 5 No 2 (2020): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (441.214 KB) | DOI: 10.33084/jsm.v5i2.1289

Abstract

Excessive fat accumulation in the body causes an increase in Body Mass Index (BMI). Increased BMI and comorbidities affect the metabolic rate. Metabolic age was influenced by the individual metabolic rate. The purpose of this study was to determine the description of metabolic age to BMI increasement. This cross-sectional study used a purposive sampling method to obtain 82 male and female subjects. Subjects were measured for BMI and metabolic age. Collected data was analyzed univariately and bivariate correlatively. The result showed a significant correlation between metabolic age and BMI (p = 0,001) with r = 0,812. The conclusion of this study is the increase in BMI, the higher the metabolic age.
Studi Literatur: Obesitas sebagai Faktor Resiko terhadap Kejadian Urolitiasis secara Klinis Hasnawati Hasnawati; Elsa Trinovita; Yudi Y Ambeng
Jurnal Surya Medika (JSM) Vol 7 No 1 (2021): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v7i1.2300

Abstract

The incidence of urolithiasis tends to relapse, causing increased mortality and medical costs. In 2015, there were 22.1 million cases of urolithiasis which caused death in about 16,000 people. Obesity is a risk factor that can increase the incidence of urolithiasis. However, there are differences in the results of studies regarding the relationship between obesity and urolithiasis. This literature review aims to analyze the factors that influence the relationship between obesity and urolithiasis. This literature review study uses a systematic review design. The data source used in this literature review is secondary data in scientific journals that have met the inclusion and exclusion criteria. Based on data synthesis from the fifteen journals studied, twelve journals stated a relationship between obesity and the incidence of urolithiasis. In contrast, the other three stated that there was no relationship between obesity and the incidence of urolithiasis. Obesity is associated with a spectrum of metabolic disorders that lead to increased excretion of urinary lithogenic factors. In addition, obesity can increase urolithiasis in types of calcium oxalate and uric acid stones.
Literatur Review: Hubungan Model Hewan Coba (Faktor Jenis Kelamin dan Hormon) pada Sensitivitas Induksi Streptozotocin sebagai Agen Diabetogenik Egi Claudia Pratiwi; Elsa Trinovita; Agnes Immanuela Toemon
Jurnal Surya Medika (JSM) Vol 7 No 2 (2022): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v7i2.2646

Abstract

Diabetes mellitus (DM) is a metabolic disease that global concern and characterized by hyperglycemia. Tests for antidiabetic agents, either discovering new drugs or antidiabetic components, have been developed using experimental animals induced with the diabetogenic agent streptozotocin. The side effects of streptozotocin were reported lower than alloxan. The sensitivity of streptozotocin induction can be relied on by several factors such as sex and hormones—the difference in results in several studies regarding the relationship between streptozotocin induction sensitivity with gender. The research method is a literature review using a systematic approach. Articles are collected through search engines like NCBI, Google Scholar, and ResearchGate by entering keywords. Based on the results of data synthesis on the relationship between streptozotocin induction sensitivity and the sex of the experimental animal, it was found that fifteen articles were related and three articles were not. Sex has a relationship with streptozotocin induction's sensitivity through the hormones estrogen, progesterone, and testosterone.
ANTHROPOMETRIC MEASUREMENT OF METABOLIC AGE USING NECK CIRCUMFERENCE Ni Nyoman Sri Yuliani; Elsa Trinovita
Jurnal Riset Kesehatan Vol 9, No 1 (2020): MAY 2020
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2683.038 KB) | DOI: 10.31983/jrk.v9i1.5400

Abstract

Excessive fat accumulation in the obese body causes chronic low-grade inflammation. The continuous occurrence will affect health, which may lead to damage to cell metabolism related to metabolic age. Therefore, anthropometric application by measuring neck circumference (NC) and body mass index (BMI) was performed. The aim of this study was to determine NC cut-off which can be used to identify the increase of metabolic age in an individual. This study is a diagnostic study using cross sectional design using subjects who met the criteria needed for this study (n = 82). BMI and NC anthropometric measurements were performed in this study. Metabolic age was measured using Bioelectrical Impedance Analyzer (BIA). Data were analyzed using 2 x 2 diagnostic table and Receiver Operating Characteristic (ROC) curve to obtain Area Under Curve (AUC). The results showed that the highest BMI was obese (65.8%) with the most common age of 30-57 years old. The result of ROC-AUC NC on metabolic age showed that AUC value of NC measurement was 0.77, cut-off ≥ 33 cm, sensitivity 71.2%, and specificity 69.6%. This study concludes that the cut-off value of NC in predicting the increase of metabolic age had good sensitivity and specificity.
Effect of Swiftlet’s (Collocalia Fuciphago) Nest Extract on the Malondialdehyde (MDA) and Superoxyde Dismutase (SOD) Activity on Hyperglycemic Rattus Norvegicius Francisca Diana Alexandra; Agnes Frethernety; Elsa Trinovita; Triawanti Triawanti
Majalah Obat Tradisional Vol 25, No 3 (2020)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.53673

Abstract

Hyperglycemia that occurs in diabetic Mellitus leads to glycation reactions in protein molecules and oxidative stress resulting in damage to cells and organs. Swiftlet’s nest believed society could lower blood glucose. The objective of the study was to evaluate the effect of Swiftlet’s nest (Collocalia fuciphago) extract on glucose level, Malondialdehyde (MDA) levels, and Superoxide Dismutase (SOD) activity in blood serum. The study used Posttest-Only with Control Group Design, consisting of 1 control group (given aqua dest) and 3 treatment groups (dose 1; 10 and 100 mg/kg BW). Each group consisted of 6 Rattus norvegicius. Before being treated, Streptozotocin-induced rat at a dose of 68 mg/kg BW intraperitoneal. On the 7th day after induction, rats had elevated glucose ± 102 - 108 mg/dL. Then the rats were given water extract Swiftlet’s nest for 28 days orally. All data were analyzed by the Kruskal-Wallis test, followed by the Mann-Whitney test, with a 95% confidence level. The results of blood glucose levels in each group (K, P1, P2 and P3) were 111.0 vs 88.5 vs 86 vs 83 mg / dL (p = 0.035), MDA levels experienced an increase in the treatment group compared to controls namely 193.50 vs 193.83 vs. 198.50 nmol / mL, p = 0.001. While the SOD enzyme activity has increased, namely 0.0050 vs. 0.0075 vs. 0.0263%. In conclusion, Swiftlet’s nest water extract can reduce blood glucose levels and increase MDA levels and SOD enzyme activity in blood serum. 
Evaluation of Gastroprotective Activity of Cemot Leaves (Passiflora foetida L.) Extracted by Ultrasonic Assisted Extraction (UAE) Against Ethanol-Induced Gastric Lesions in Rats Elsa Trinovita; Fatmaria Fatmaria
Majalah Obat Tradisional Vol 25, No 2 (2020)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.53691

Abstract

Peptic ulcers are one of the global health problems in the world. However, most of these drugs have unwanted side effects and drug interactions that this research focuses on the use of plant products as an anti gastric ulcer. The phytochemical of Passiflora foetida L. leaves or better known by the name of the Central Borneo with 'Cemot' such as flavonoids, alkaloids, and tannin has potential as a gastroprotective. This study used the method of extraction of non-conventional, namely the UAE, because it has advantages compared with other conventional methods. This study aims to investigate the gastroprotective activities of ethanol extract of Passiflora foetida leaves-UAE. Cemot extract was obtained by UAE method using a concentration of ethanol (70%), the ratio of sample/liquid (10g/mL) for 3 minutes. Three groups of rats treated with a respective dose of the extract (50, 100 and 200 mg/kg BW), one group of rats treated with omeprazole 36 mg/kg BW for seven days before peptic ulcer induction using ethanol. The activity gastroprotective with measurement of lesion of gastric ulcer index and the percentage of inhibition ulcer. Group of rats treated with 200 mg/kg BW extract showed a decreased the ulcer index and ulcer inhibition than the other extract dosage groups, respectively 2.83 and 35.34%. Conclusion: Based on the results of this study concluded that the cemot extract has potential as a gastroprotective.
Pemberdayaan Gerakan Masyarakat 4G (Go Green, Go Health, Go Clean dan Go Smart) di UPTD Puskesmas Tangkiling Elsa Trinovita; Dewi Klarita Furtuna; Silvani Permatasari; Astri Widiarti; Galih Indra Permana
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol 7 No Special-1 (2022): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v7iSpecial-1.2312

Abstract

Indonesia is one of the countries set as a corona disaster emergency with the increasing Covid-19 case. One of the factors that caused an increase in Covid-19 cases was the lack of public awareness in implementing 5-M prevention behavior using masks, hand washing using soap and running water, keeping distance, staying away from the crowd, and limiting mobilization and interaction) in his daily life can be a risk transmission in society. Therefore, an approach was carried out in increasing public awareness of the new normal adaptation in the face of the Covid-19 pandemic condition by promoting the "4G Movement" (Go Green, Go Health, Go Clean and Go Smart) at the UPTD Puskesmas Tangkililing carried out by the Faculty Team Medicine of Palangka Raya University. This activity aims to increase public awareness and understanding of the importance of good health behavior by applying a strict health protocol in the condition of the Covid-19 pandemic as a step in supporting government programs and maintaining personal, family, and community health in anticipation of the spread of Covid-19. It implements this activity in the form of a lecture/socialization, demonstration, free pocket book distribution, and educational video playback in animation. This activity runs smoothly and occurs interactive dialogue with respondents in the UPTD Puskemas environment. The 4G movement is one of the programs that contribute positively and can be applied by the community in increasing compliance in implementing a health protocol.
Antibacterial activity of extract sangkareho leaves (Callicarpa longifolia LAM.) on Salmonella typhi and Staphylococcus epidermidis Silvani Permatasari; Ervi Audina Munthe; Muntir Guru Singa; Elsa Trinovita; Ratna Widayati; Natalia Sri Martani; Anna Marthea Veronica
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 13, No 1, (2022)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol13.Iss1.art7

Abstract

Background: The most commonly found disease-causing microorganisms are the Salmonella typhi and Staphylococcus epidermidis bacteria. S.typhi is a gram-negative bacterium that causes typhoid fever, and S.epidermidis is a gram-positive bacterium that attacks mucous membranes and human skin. Sangkareho (Callicarpa longifolia Lam.) is one of the indigenous herbal plants of Central Kalimantan, which is empirically used as a wound medicine, diarrhea, diabetic, anti-inflammatory, and can be an antibacterial agent.Objective: This study used six groups are concentrations of 10%, 25%, 50%, and 100%, Chloramphenicol as a positive control, and dimethyl sulfoxide (DMSO) as a negative control. Methods: The method used for this test is the well diffusion method. In Nutrient Agar (NA) media, holes were made to insert 40 μl of each extract concentration, positive and negative control with four repetitions, then incubated for 18-24 hours at 37ºC. Data analysis using the One Way Anova test.Results: The research findings showed that ethanol extract of sangkareho leaves with all concentrations had an inhibitory effect against both bacteria tested.Conclusion: The ethanol extract of sangkareho leaves at the concentration of 10% was found to be the optimum and at the concentration of 100% was the maximum effectiveness for inhibiting S. typhi and S. epidermidis.
Edukasi Penggunaan Supplemen Kesehatan dan Potensi Beberapa Jenis Tanaman sebagai Imunomodulator di Kelurahan Palangka Elsa Trinovita; Fatmaria Fatmaria
Jurnal Pengabdian ILUNG (Inovasi Lahan Basah Unggul) Vol 2, No 2 (2022)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ilung.v2i2.6188

Abstract

Abstrak Mengkonsumsi suplemen kesehatan dan obat berbahan herbal secara berlebihan dapat menimbulkan efek yang tidak diharapkan bagi tubuh. Temulawak, kunyit, jahe dan lain-lain dapat mempunyai aktivitas farmakologik sebagai sehingga dapat digunakan oleh masyarakat sebagai tindakan preventif. Oleh karena itu, diperlukan peranan tenaga kesehatan dalam memberikan edukasi kesehatan ke masyarakat. Pelaksanaan kegiatan di Kelurahan Palangka, Kota Palangka Raya dalam bentuk penyuluhan, pembagian buku saku, evaluasi dalam bentuk pre-test/pos-test dan umpan balik. Pelaksanaan kegiatan ini berjalan dengan lancar dengan adanya interaksi komunikasi yang efektif antara narasumber dan peserta kegiatan. Kegiatan ini memberikan manfaat positif bagi masyarakat dalam meningkatkan pengetahuan dan pemahaman terkait informasi ilmiah yang disampaikan oleh narasumber.  Kata kunci: Covid-19; Imunomodulator; Suplemen; Tanaman 
Studi Literatur: Pengaruh Konsumsi Junk Food terhadap Obesitas: Literature Review: Effect of Junk Food Consumption on Obesity Lelia Pebriani; Agnes Frethernety; Elsa Trinovita
Jurnal Surya Medika (JSM) Vol. 8 No. 2 (2022): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v8i2.3103

Abstract

Data based on the World Health Organization (WHO) in 2018 shows that 650 million people in the world suffer from obesity. Indonesia is a country that ranks 4th in Southeast Asia with 14.3% of obesity cases. One of the factors that causes the increase in obesity is the consumption of junk food. However, there are differences in research results regarding the effect of junk food consumption on obesity in terms of the frequency of junk food consumption. The purpose of this literature review is to determine the effect of the frequency of consumption of junk food on obesity when studied scientifically. This literature review research uses a systematic review approach. Sources of research data using secondary data include scientific journals that meet the inclusion and exclusion criteria. Based on the synthesis of data from 15 journals studied, there are 13 journals which state that consumption of junk food has an effect on obesity, and 2 journals which state that it does not have an effect of consumption of junk food on obesity. Most obese patients have leptin resistance, which will make leptin levels high so that it does not cause a decrease in appetite.
Co-Authors Agnes Frethernety Agnes Frethernety Agnes Frethernety Alexandra, Francisca Diana Amelia, Rosa Angeline Novia Toemon Angeline Novia Toemon, Angeline Novia Anna Marthea Veronica Arif Rahman Jabal Astri Widiarti Augustina, Indria Clarissa Ester Diana Putri Dewi Klarita Furtuna Dian Mutiasari, Dian Egi Claudia Pratiwi Elma, Pransiska Ervi Audina Munthe Fadhiyatulqalbi Ahmad, Farah Fauziyah Fatmaria Fatmaria Fatmaria Fatmaria Fatmaria Fatmaria Fatmaria Fatmaria, Fatmaria Fiska, Friskilla Andia Francisca Diana Alexandra Francisca Diana Alexandra Frethernety, Agnes Furtuna, Dewi Klarita Galih Indra Permana Hanasia, Hanasia Handayani, Septi Hasnawati Hasnawati Immanuela Toemon, Agnes Indria Augustina Jesika, Debora Lelia Pebriani Mikko Uriamapas Ludjen Muhammad Noer Perdana Sakti Widodo Muntir Guru Singa Natalia Sri Martani Ni Nyoman Sri Yuliani Ni Nyoman Sri Yuliani Nugrahini, Sintha Patricia, Tisha Permatasari, Silvani Pratama, Daniel Ari Ranintha br Surbakti Ranti, Dalia Ratna Widayati Ratna Widayati Renaldy, Renaldy Rian Ka Praja Saputra, Aldi Aditya Savitri, Dilasari Silvani Permatasari Tasya, Tasya Toemon, Agnes Immanuela Triawanti Triawanti Trilianty Lestarisa Turnip, Oktaviani Naulita Valencia, Regina Widayati, Ratna Widiarti, Astri Ysrafil, Ysrafil Yudi Y Ambeng Zhofiroh, Nabilatul