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All Journal CHEMPUBLISH JOURNAL Jurnal Surya Medika JMM (Jurnal Masyarakat Mandiri) Bubungan Tinggi: Jurnal Pengabdian Masyarakat Community Empowerment Jurnal Farmasi dan Sains Indonesia (JFSI) Journal of Experimental and Clinical Pharmacy (JECP) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Sinteza Borneo Journal of Pharmacy Journal of Pharmascience
Muhammad Priyadi
Universitas Palangka Raya
Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Uji Potensi Daya Hambat Ekstrak Metanol Biji Jintan Hitam (Nigella Sativa L.) Terhadap Bakteri Streptococcus Guntur Satrio Pratomo; Nurul Chusna; Muhammad Priyadi
Jurnal Surya Medika (JSM) Vol 6 No 1 (2020): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v6i1.1615

Abstract

One of the plants that are often used as medicinal plants is Black Seed, Black Seed is a medicinal plant known in Indonesia by the name of black cumin. Black cumin seeds and essential oils (Nigella sativa L.) have been widely used in traditional medicine. Many studies have proven the effects of Nigella sativa extract. In various studies, black cumin seed oil shows efficacy as an anti-cancer, anti-free radical and immunomodulator, analgesic, antimicrobial, anti-inflammatory, a spasmolytic, bronchodilator, hepatoprotective, and anti-hypertensive Advanced chemical analysis found that Black Seed contains carotene that is converted into vitamin A by heart. The purpose of this study was to determine the potential inhibition of methanol extract of black cumin seeds (Nigella Sativa L.) against Streptococcus. This research uses a quantitative approach with an experimental method. This research was conducted in the Pharmacognition and Microbiology Laboratory of the Faculty of Health Sciences, Muhammadiyah University, Palangkaraya. The sample used was a sample of plant material, namely Black Cumin Seed (Nigella sativa L) which had been dried and pollinated and then extracted and then tested against bacteria. The results of testing the antibacterial activity showed that from low concentration to high concentration the diameter of the resulting inhibition showed that the activity could inhibit the bacteria streptococcus mutants. The highest inhibition at a concentration of 6% is 0.83 mm and the lowest concentration at a concentration of 3% against Streptococcus mutants.
PELATIHAN PEMBUATAN SABUN ANTISEPTIK CAIR BERBAHAN DASAR TANAMAN RAMBUSA KALIMANTAN TENGAH Evi Mulyani; Nurul Chusna; Muhammad Priyadi
JMM (Jurnal Masyarakat Mandiri) Vol 6, No 1 (2022): Februari
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (316.882 KB) | DOI: 10.31764/jmm.v6i1.6575

Abstract

Abstrak: Pandemi COVID-19 telah mengubah kebiasan kehidupan di masyarakat termasuk menjaga kebersihan tangan melalui cuci tangan termasuk di lingkungan sekolah. Keterbatasan dalam mendapatkan akses pendidikan dan pelatihan selama pandemi ini melanda menjadikan siswa sekolah memerlukan kegiatan di luar sekolah untuk meningkatkan keterampilan sebagai bekal tambahan. Pengabdian ini bertujuan untuk meningkatkan pengetahuan siswa SMA dalam pembuatan sabun antiseptik cair dengan bahan dasar tanaman rambusa Kalimantan Tengah. Pengabdian dilakukan kepada siswa/i SMA Muhammadiyah 1 Palangka Raya dengan melakukan pelatihan pembuatan sabun antiseptik cair secara daring dan luring terhadap 24 peserta. Evaluasi kegatan dilakukan melalui asessmen awal dan akhir berupa pemberian instrumen kuisioner kepada peserta pelatihan. Hasil menunjukkan telah terjadi peningkatan pengetahuan siswa/i SMA Muhammadiyah 1 Palangka Raya sebesar 30,4%.Abstract: The COVID-19 pandemic has changed the habits of life in the community, including maintaining hand hygiene through hand washing, including in the school environment. Limitations in getting access to education and training during this pandemic have made school students need activities outside of school to improve skills as additional provisions. This service aims to increase the knowledge of high school students in making liquid aniseptic soap with plant-based ingredients typical of Central Kalimantan. The service was carried out to students of SMA Muhammadiyah 1 Palangka Raya by conducting online and offline training on making liquid antiseptic soap for approximately 24 participants. Activity evaluation is carried out through initial and final assessments in the form of giving a questionnaire instrument to the training participants. The results show that there has been an increase in knowledge of students at SMA Muhammadiyah 1 Palangka Raya by 30.4%.
EDUKASI TENTANG VIRUS CORONA DAN PEMBUATAN JAMU EMPON – EMPON UNTUK PENANGANAN VIRUS CORONA DI JUNJUNG BUIH III KOTA PALANGKARAYA Nurul Chusna; Evi Mulyani; Muhammad Priyadi; Ade Irawati; Drenikha Sikhe R; Rismadani Safitri
JMM (Jurnal Masyarakat Mandiri) Vol 5, No 1 (2021): Februari
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (837.28 KB) | DOI: 10.31764/jmm.v5i1.3543

Abstract

Abstrak: Seluruh dunia saat ini tengah dihebohkan dengan Corona Virus Disease (COVID-19) yang tak pernah disangka akan menyebabkan pandemi global dengan jumlah total kasus yang sangat banyak dan terus menyebar ke seluruh dunia termasuk hingga mencapai Kota Palangka Raya, Indonesia. Penyebaran informasi yang keliru saat pandemi dapat membuat masyarakat bingung, resah dan takut sehingga diperlukan upaya edukasi maupun sosialisasi agar masyarakat menjadi paham dan tenang. Pengabdian ini bertujuan untuk melakukan edukasi tentang penanganan virus corona/COVID-19, pembuatan jamu empon-empon agar dapat mengurangi dan mencegah terjadinya risiko penyebaran corona di Junjung Buih III Kota Palangka Raya dengan melibatkan mitra ketua RW dan perkumpulan ibu-ibu. Kegiatan ini dilakukan melalui 3 tahapan yaitu persiapan (observasi), pelaksanaan kegiatan (edukasi dan sosialisasi) dan evaluasi. Hasil dari kegiatan ini adalah kegiatan ini diikuti oleh 32 warga Junjung Buih III yang mampu meningkatkan pemahaman dan kesadaran warga dalam pencegahan virus corona yang terlihat pada penggunaan masker, hand sanitizer, mencuci tangan maupun mengkonsumsi jamu empon-empon yang dibuat langsung di rumah. Abstract:  The whole world is currently in shock with the Coronavirus Disease (COVID-19) which was never expected to cause a global pandemic with a very large number of cases and continues to spread throughout the world including reaching Palangka Raya City, Indonesia. The dissemination of misinformation during a pandemic can make people confused, anxious, and afraid so that educational and socialization efforts are needed so that people understand and are calm. This activity aims to provide education about the handling of the coronavirus/COVID-19, making herbal medicine jamu empon-empon in order to reduce and prevent the risk of spreading corona in Junjung Buih III, Palangka Raya City by involving RW chief partners and women's associations. This activity is carried out in 3 stages, namely preparation (observation), implementation of activities (education and socialization), and evaluation. The result of this activity was that this activity was attended by 32 residents of Junjung Buih III who were able to increase people's understanding and awareness of the prevention of the coronavirus which can be seen in the use of masks, hand sanitizers, washing hands, and also  consuming jamu empon-empon made directly at home (home made).
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETIL ASETAT DAUN RAMBUSA DAN DAUN KARAMUNTING TERHADAP Streptococcus mutans Muhammad Priyadi; Nurul Chusna; Guntur Satrio Pratomo
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 2 (2022): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v7i2.875

Abstract

Empirically, many natural ingredients have been used in preventive care for the treatment of dental and oral disorders. Chronic conditions on the teeth with the appearance of plaque and tooth decay are referred to as dental caries which are characterized by toothache and also digestive disorders. Streptococcus mutans is known as the bacteria that most often causes dental caries. Karamunting and rambusa plants have enough potential as antibacterials because there have been many studies that have shown their potential as antibacterial activities. The purpose of this study was to determine the antibacterial activity of ethyl acetate extract of karamunting leaves and rambusa leaves against Streptococcus mutans. Antibacterial activity test using well diffusion method by measuring the diameter of the inhibition zone. The results showed that the ethyl acetate extract of karamunting leaves 1%, 5%, 10%, 15%, 20% had inhibition zone diameters of 4.6 mm, 4.1 mm, 0 mm, 0 mm, 0 mm, respectively while rambusa leaves 1%, 5%, 10%, 15%, 20% had inhibition zone diameters of 4.4 mm, 8.7mm, 9.4 mm, 5.3mm and 8.8mm respectively. The ethyl acetate extract of karamunting and rambusa leaves is known to have weak antibacterial activity in the resistant category.
Phytochemical and Cytotoxic Test of Durio kutejensis Root Bark on MCF-7 Cells Muhammad Priyadi; Haryoto Haryoto; Amaliyah Dina Anggraeni; Heng Yen Khong
Borneo Journal of Pharmacy Vol. 4 No. 1 (2021): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v4i1.1443

Abstract

Durio kutejensis has known potential as herbal medicine in Kalimantan. Many things can be explored from D. kutejensis related pharmacological activity in every part of the plant included root bark. This study investigated the phytochemical content with a qualitative test and tested cytotoxic activities of D. kutejensis root bark on MCF-7 cell lines. Cytotoxic activity tested on MCF-7 cells with MTT assay method. The result showed that D. kutejensis root bark contains flavonoid, tannin, terpenoid, phenol, and saponin. IC50 value for ethanol extracts of root bark, n-hexane fractions, ethyl acetate fractions, and doxorubicin on MCF-7 cells were 761.29; 280.5; 207.08; and 0.25 μg/mL, respectively. In conclusion, D. kutejensis root bark has some secondary metabolites but no cytotoxic activity on MCF-7 cells. Further research is needed to explore the anticancer activity of secondary metabolites on some other cancer cells and other pharmacological activities.
Phytochemical Profile and Antioxidant Activity of Bajakah Kalalawit Leaf Extract Priyadi, Muhammad; Gunawan, Yohanes Edy; Saputra, Rizki Rachmad; Decenly, Decenly; Citrariana, Shesanthi
Journal of Experimental and Clinical Pharmacy (JECP) Vol 5, No 1 (2025): February 2025
Publisher : Poltekkes Kemenkes Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jecp.v5i1.1321

Abstract

Natural products have long been recognized for their significant role in supporting human health, with natural ingredients playing an essential part in disease treatment and wellness across generations. The bajakah species, particularly bajakah kalalawit (Uncaria gambir Roxb.), has gained attention in recent research due to its potential bioactive compounds. Especially, its antioxidant properties from any part of plant has potential to explore. This study aims to determine the various secondary metabolite compounds possessed by bajakah kalalawit leaves and test their antioxidants. Bajakah kalalawit leaves were extracted using reflux with aqueous solvents, checked for phytochemical profiles using GC-MS, and conducted antioxidant tests using the DPPH method. Based on the phytochemical test, there are 22 predicted compounds in the extract and the antioxidant test results showed an IC50 value of 14.44 ppm. In conclusion, bajakah kalalawit leaf aqueous extract has antioxidant activity and is supported by bioactive compounds.
Empowering Talian Kereng Village farmer groups through independent organic fertilizer production based on local resources for sustainable agriculture Rosalina, Reny; Hermayantiningsih, Dwi; Priyadi, Muhammad; Decenly, Decenly; Putri, Alayya Adistia; Sametri, Ni Wayan Septia
Community Empowerment Vol 10 No 2 (2025)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/ce.12340

Abstract

Talian Kereng Village, located in Katingan Hilir District, Central Kalimantan, faces challenges regarding the availability of fertilizers for upland rice farmers on peatlands, with a heavy reliance on government-subsidized chemical fertilizers. To address this issue, a community empowerment program was implemented to promote independent organic fertilizer production using local resources. The program involved education and training for the Maju Bersama farmer group on the production of decomposers, liquid organic fertilizer (eco enzyme), and compost from household waste and harvest residues. The results showed a significant increase in knowledge, where initially, 53.9% of participants had limited understanding of decomposer and eco enzyme production, but after the training, 95.3% of participants fully comprehended the material. Furthermore, all participants became skilled in producing organic fertilizers. This program is expected to enhance farmers' self-sufficiency in meeting fertilizer needs, reduce dependence on chemical fertilizers, and support agricultural sustainability in Talian Kereng Village.
Aktivitas Psikostimulan Tanaman Bajakah (Spatholobus suberectus) : Studi In Silico Terhadap Protein 4M48-Dopamine Transporter Priyadi, Muhammad; Saputra, Rizki Rachmad; Gunawan, Yohanes Edy; Citrariana, Shesanthi; Decenly, Decenly; Febrianto, Yahya
Jurnal Farmasi & Sains Indonesia Vol 6 No 2 (2023)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol6no2p149-154

Abstract

Bajakah plants (Spatholobus suberectus) have been widely used by Dayak tribes in Kalimantan with various properties that are believed and have also been studied for various tests of phytochemical compound content and pharmacological tests. Secondary metabolite compounds from bajakah (Spatholobus suberectus) have potential as psychostimulant compounds. The purpose of this study was to investigate the psychostimulant activity of bajakah plants (Spatholobus suberectus) through analysis of the interaction between bajakah secondary metabolite compounds and the 4M48-Dopamine Transporter receptor (PDB: 4M48), which is one of the dopamine transporter proteins. Ligand and receptor interactions were analyzed using molecular docking method with Autodock Vina 4 application with nortriptyline compound as native ligand and 15 secondary metabolite compounds for testing. The results of docking analysis showed that the standard ligand nortriptyline compound has an affinity value of -10.2 kcal/mol. There are 3 compounds from bajakah that have affinity values close to the standard compounds plathymenin, butein and eriodictyol with affinity values of -9.7 kcal/mol, -9.4 kcal/mol and -9.2 kcal/mol respectively. Based on the analysis conducted, it can be concluded that bajakah plants (Spatholobus suberectus) have the potential to be developed as psychostimulant therapy.
Anticaries Potential of Temu Kunci-Serai Ethyl Acetate Extract Combination: In Vitro and Molecular Studies Approach Priyadi, Muhammad; Saputra, Rizki Rachmad
Chempublish Journal Vol. 7 No. 1 (2023): Chempublish Journal
Publisher : Department of Chemistry, Faculty of Science and Technology Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/chp.v7i1.26098

Abstract

Dental caries is one of the problems in dental disorders suffered by many people. There have been many ways of handling such as using temu kunci and lemongrass plants. This study aims to determine the antibacterial activity of caries in vitro and predict the mechanism of action of the bacteria that cause caries Streptococcus mutans.  Temu kunci and lemongrass were extracted using ethyl acetate solvent. antibacterial tests against Streptococcus mutans were carried out using diffusion tests with a combination treatment of temu kunci: serai extracts 5% b/v: 5% b/v, 5% b/v: 10% b/v, and 10% b/v: 5% b/v. The positive control used amoxicillin and DMSO as a negative control. Potency as an anticaries drug of drived compound from Temu Kunci and Serai were evaluated by molecular docking using glucosyltransferase (3AIC). The results showed that the combination of temu kunci and serai with concentration 10% b/v: 5% b/v has potential as anticaries against Streptococcus mutans. Molecular studies depicted that Panduratin A, Isopanduratin, and 1,3-O-di-p-coumaroylglycerol have great activity toward 3AIC, respectively. Especially for Panduratin A and Isopanduratin, those compound depicted great and similar binding affinity (-8.4 kcal mol-1) that lower than Acarbose as native ligand  (-8.3 kcal mol-1). Furthermore, those compound binding similarity ilustrated activity mechanism similarly with native ligand toward receptor. Additionally, the profiling drug-target interaction suggested Temu Kunci’s derived compounds have great potential as anticaries treatment.   
TRANSFER TEKNOLOGI BIOPESTISIDA SEBAGAI UPAYA PENINGKATAN PRODUKTIVITAS PETANI PADA KELOMPOK TANI DI PALANGKA RAYA Muhammad Priyadi; Rian Ka Praja; Rts Sherly Dwi Jayanti; Decenly Decenly; Jonathan Kaharati; Mohammad Bimo Prakosa; Betrand Fernando
JMM (Jurnal Masyarakat Mandiri) Vol 9, No 6 (2025): Desember
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jmm.v9i6.34861

Abstract

Abstrak: Masalah yang sering dihadapi petani adalah gangguan hama dan mahalnya harga pestisida kimiawi. Pengabdian ini bertujuan untuk meningkatkan pengetahuan dan keterampilan kelompok petani dalam membuat hingga menggunakan biopestisida nabati yang ramah lingkungan dan lebih ekonomis. Metode pengabdian terdiri dari penyuluhan, pelatihan, dan praktik langsung bagi 20 anggota kelompok tani. Evaluasi kegiatan dilakukan dengan menggunakan instrumen pre-test dan post-test sebagai pengukur tingkat pemahaman peserta. Dilihat dari skor pre-test yang berkisar 40-80% menjadi 100% pada post-test, kegiatan ini berhasil memberikan solusi bagi petani dalam pengendalian hama dengan pembuatan biopestisida alami dan bertransisi menuju sistem pertanian yang lebih organik, efisien, dan berkelanjutan.Abstract: The problems often faced by farmers are pest infestations and the high cost of chemical pesticides. This community service program aimed to improve farmers' knowledge and skills in producing and using plant-based biopesticides as an eco-friendly and economical alternative. The method involved counseling, training, and hands-on practice for 20 members of the farmer group. The program was evaluated using pre- and post-tests method to measure the increase in participants' understanding. Judging by the pre-test scores, which ranged from 40-80% and increased to 100% in the post-test, this activity successfully provided a solution for farmers in pest control through the production of natural biopesticides, enabling them to transition to a more organic, efficient, and sustainable agricultural system.
Co-Authors Ade Irawati Adistia P, Allaya Ahmad Irawan, Ahmad Amaliyah Dina Anggraeni Andra Ari P., Eko Marwanto Heru Mulyantoro Dwi Hermayantiningsih Anisa Rahma Fauziah Anograh R, Defilia Ayuchecaria, Noverda Betrand Fernando Citrariana, Shesanthi Decenly Decenly Decenly Decenly Decenly Decenly Decenly, Decenly Defilia Anogra Riani Drenikha Sikhe R Elphasa H, Shavira Esterlita, Anggraeni Putri Evi Mulyani Fauziah, Anisa Rahma Franz June Navirius Galeno, Nathanael Neda Gunawan, Yohanes E Gunawan, Yohanes Edy Guntur Satrio Pratomo Haryoto Haryoto Heng Yen Khong Isnawati Isnawati Jonathan Kaharati June N, Franz Mohammad Bimo Prakosa Nurul Chusna Nurul Chusna Opi Indriani Putri, Alayya Adistia Rahmman, Sudarman Reny Rosalina, Reny Rian Ka Praja Rismadani Safitri Rizki Rachmad Saputra Roselia, Jessica Alexandra Rts Sherly Dwi Jayanti Sametri, Ni Wayan Septia Shesanthi Citrariana Thathit Suprayogi Thathit Suprayogi Yahya Febrianto Yahya Febrianto Yohanes Edy Gunawan