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Determinasi Kejadian Perilaku Seksual Pranikah dalam Aktivitas Pacaran Remaja di Kalimantan Tengah Shesanthi Citrariana; Risqika Yuliatantri Paramawidhita; Halida Suryadini; Muhammad Dawam; Awumistiko Awumistiko
Jurnal Surya Medika (JSM) Vol 7 No 1 (2021): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v7i1.2232

Abstract

Based on the 2017 IDHS survey, most adolescent women (80%) and men (84%) reported dating. The 15-17 years is the age group when adolescents start dating. Teenage dating activities lead to sexual behavior, such as holding hands, hugging, kissing lips, touching sensitive parts, and having sex. This study aims to determine the influence of the background characteristics of adolescents (age, area of residence, level of education) and social patterns (having friends having premarital sex, having the urge because of friends, influencing friends to have premarital sex, considering virginity important) on the incidence of premarital sex in Central Kalimantan 2017. Secondary data were obtained from the 2017 IDHS survey. Data analysis was performed by univariate, bivariate (Spearman rho test), and multivariate (logistic regression test). The results showed that 88% of respondents had sexual behavior orientation, and 12% did not. The correlation analysis explains a significant relationship between premarital sexual behavior and the area of residence. Respondents who live in cities are 3.47 times more likely to commit premarital sexual behavior (α<0,05 = 0,021; OR = 3.47). In addition, there is sufficient evidence to suggest a relationship between premarital sexual behavior and education level, respondents who attend high school and above are 2.71 times more likely to have premarital sexual behavior (α<0,10 = 0,066; OR = 2.71). Meanwhile, other variables from background characteristics and social patterns have no significant relationship/do not influence premarital sexual behavior. So it can be concluded that the background characteristics in the area of residence (Sig Wald <0.0) have a significant partial effect on adolescents' incidence of premarital sexual behavior in Central Kalimantan.
Formulasi dan evaluasi SNEDDS (Self Nanoemulsifying Drug Delivery System) ekstrak daun pepaya (Carica papaya L.) sebagai analgesik Bambang Hernawan Nugroho; Shesanthi Citrariana; Ita Nurma Sari; Reny Nadya Oktari; M Munawwarah
Jurnal Ilmiah Farmasi Vol. 13 No. 2 (2017): Jurnal Ilmiah Farmasi
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.vol13.iss2.art5

Abstract

Intisari Latar belakang: SNEDDS dipilih karena dapat meningkatkan absorbsi obat yang memiliki kelarutan rendah didalam air seperti zat aktif yang berasal dari ekstrak tanaman.Tujuan: Penelitian ini bertujuan untuk membuat suatu inovasi sediaan obat dengan memanfaatkan sistem penghantaran obat baru yang berupa Self Nanoemulsifiying Drug Delivery System (SNEDDS)menggunakan zat aktif ekstrak daun papaya (Carica Papaya L.) yang berkhasiat sebagai analgesik.Metode: SNEDDS ekstrak daun pepaya Carica Papaya L.) dibuat dengan metode high energy. ekstraksi dilakukan dengan metode maserasi daun yang telah dikeringkan menggunakan etanol 96% kemudian ekstrak diuapkan dengan rotary evaporator hingga menjadi ekstrak pekat dan ditambahkan kedalam formulasi. Sediaan SNEDDS dibuat 4 formula dengan fase minyak isopropil miristat, surfaktan PEG 400, dan kosurfaktan tween 80 menggunakan teknik high energy. Evaluasi terhadap sediaan berupa ukuran partikel, persen transmitan, dan freeze thawing. Formulasi SNEDDS yang memiliki kesesuaian parameter evaluasi akan dilakukan pengujian terhadap aktivitas analgesiknya secara in vivo menggunakan mencit galur balb-c yang diinduksi asam asetat 1% kemudian hasil uji dibandingkan dengan aktivitas analgesik asam mefenamatHasil: Hasil uji memperlihatkan bahwa semua formula memiliki ukuran partikel <200nm dan persen transmitan >90%. Hasil uji aktivitas analgesik SNEDDS secara in-vivo menunjukan bahwa persen inhibisi nyeri rata-rata SNEDDS ekstrak daun pepaya adalah 94,55%.Kesimpulan: Formula SNEDDS ekstrak daun pepaya dari F4 memenuhi parameter stabilitas yang baik dengan ukuran partikel yang paling kecil yaitu 77,1 nm. Persen inhibisi nyeri dari SNEDDS ekstrak daun papaya pada mencit galur balb-c yang diinduksi asam asetat adalah 94,55%.Kata kunci : SNEDDS, Carica Papaya L., analgesik
Validasi Metode Analisis Matriks Patch Domperidon Maleat dengan Perbedaan Polimer Menggunakan Spektorfotometri UV-Vis Shesanthi Citrariana; Oktavia Indrati; Puspa Dwi Pratiwi; Ita Nurma Sari; Ari Wibowo
Pharmacon: Jurnal Farmasi Indonesia Vol 18, No 2 (2021)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v18i2.14576

Abstract

Uv-Vis spectrophotometry is an analytical method that can be used to determine the levels of domperidon maleate contained in transdermal patches with different polymers. The analysis method needs to be validated to prove that it can provide measurement results that match its designation. The purpose of this study is to prove that uv-vis spectrophotometry methods can provide the specificity, linearity, thoroughness, and precision that meet the requirements. In this study, linearity was known by calculating the r value on the curve of the relationship between levels and absorbance. Precision is obtained based on rsd value. Accuracy is calculated based on the return value. Selectiveity is known by means of identity confirmation that calculates the absorbance ratio at different wavelengths. The results showed that the method meets the requirements with a value of r=0.999; RSD precision results at a level of 10 ppm obtained RSD 0.236%. The accuracy values of 80%, 100%, and 120% in the matrix of transdermal domperidon maleate patches with PVA and PVP polymers respectively recovery was 99.50%, 101.15%, and 99.13%.. In the matrix of transdermal patches domperidon maleate with polymers HPMC and Na-CMC respectively recovery was 100.91%, 100.31%, and 100.67%. In the matrix of transdermal domperidon patches with HPMC and EC polymers respectively recovery was 98.00%, 98.00%, and 99.00%. The identity confirmation results on the transdermal domperidon patch matrix with PVA and PVP polymers, HPMC and Na-CMC, as well as HPMC and EC respectively have ratio value close to the standard solution with an average value of 0.800; 0,806; and 0.808. It can be concluded that the method of analyzing the levels of domperidone maleate in matrix of transdermal patches has qualified for good validity.
Studi Perbandingan Disolusi In-Vitro Pada Formula Tablet Levofloksasin Immediate-Release Menggunakan Variasi Kadar Disintegran Sodium Starch Glycolate Shesanthi Citrariana; Endang Lukitaningsih; Akhmad Kharis Nugroho
Majalah Farmaseutik Vol 16, No 1 (2020)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (430.539 KB) | DOI: 10.22146/farmaseutik.v16i1.48941

Abstract

Levofloksasin merupakan antibiotik yang digunakan dalam terapi Community Acquired Pneumonia (CAP) dengan prevalensi cukup tinggi di Indonesia. Sodium starch glycolate (SSG) merupakan eksipien yang berfungsi sebagai disintegran. SSG direkomendasikan dalam formula tablet dengan konsentrasi 1-4% karena konsentrasi yang lebih tinggi dapat mengurangi kemampuan disintegrasinya. Kinetika pelepasan obat memiliki nilai yang sangat penting dalam pengembangan dan kontrol kualitas obat. Perubahan kualitatif dan kuantitatif eksipien dalam formula dapat mengubah kinetika pelepasan dan kinerja in-vivo. Peneliltian ini bertujuan untuk melakukan studi perbandingan kinetika pelepasan obat pada tablet levofloksasin yang diformulasikan menggunakan berbagai konsentrasi SSG. Hasil penelitian ini memperlihatkan bahwa konsentrasi SSG 1,33-5,33% dalam formula tidak memberikan perbedaan model kinetika pelepasan obat. Hal ini terlihat dari nilai f1 (3,12-8,50) dan f2 (56,16-77,43) yang berada pada rentang kriteria. Tablet levofloksasin Immediate-release (IR) yang diformulasikan, mengikuti pemodelan First-Order kinetik dengan kriteria nilai R2_adj tertinggi, MSE dan AIC terkecil, serta MSC terbesar dibandingkan dengan model kinetika lainnya. Pemodelan menggunakan Korsmeyer-Peppas memperlihatkan bahwa mekanisme transport dari tablet levofloksasin mengikuti persamaan Fickian semu (n<0,5) sehingga menggambarkan pelepasan obat dari matriks non-swellable.
EDUKASI “PENOL” (PENYEMARAK ESSENTIAL OIL) DAN PELATIHAN PRODUK SEDIAAN GUNA KESEHATAN BAGI KOMUNITAS MILENIAL DI KOTA PALANGKARAYA: Education "Penol" (Enlivening Essential Oil) and Training on Dosage Products for Health for the Millennial Community in Palangkaraya City Risqika Paramawidhita; Halida Suryadini; Shesanthi Citrariana
J-Dinamika : Jurnal Pengabdian Masyarakat Vol 7 No 3 (2022): Desember
Publisher : Politeknik Negeri Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25047/j-dinamika.v7i3.3300

Abstract

Essential Oil memiliki multimanfaat yang baik untuk digunakan dalam sediaan aromaterapi. Seiring perkembangan zaman dengan teknologi semakin canggih sehingga mendukung maraknya pemakaian produk-produk yang dikenal dengan “Back To Nature” salah satunya dengan mengangkat pamor dari essential oil terutama produk untuk kesehatan, dikarenakan dengan menggunakan minyak jenis ini akan memberi rasa relaksasi pada tubuh. Kaum millenial merupakan generasi maju sebagai contoh permodelan di masyarakat dan menjadi mitra yang akan mendukung untuk menyemarakkan penggunaan essential oil. Hal ini merupakan faktor penting dilakukan kegiatan pengabdian masyarakat tentang pelatihan pembuatan sediaan aromaterapi berbahan essential oil  kepada sekelompok komunitas milenial di kota Palangka Raya. Kegiatan ini diawali dengan pemberian edukasi dan menambah ketertarikan tentang essential oil, pelatihan pembuatan sediaan aromaterapi, serta di akhiri dengan evaluasi kegiatan pengabdian masyarakat dilakukan dengan pemberian pre dan post test dalam bentuk kuisioner. Hasil kegiatan yang didapatkan ialah adanya peningkatan pengetahuan, ketertarikan dan ketrampilan membuat sediaan aromaterapi bagi pihak mitra serta dapat menjadi inspirasi untuk dapat menyemarakkan potensi dari essential oil dalam mewujudkan komunitas milenial yang kreatif dan inovatif.
Edukasi Cara Sikat Gigi Pada Ibu Siswa TK Perwanida Kotawaringin Barat Kalimantan Tengah Shesanthi Citrariana; Tri Megawati
Faedah : Jurnal Hasil Kegiatan Pengabdian Masyarakat Indonesia Vol. 1 No. 2 (2023): Mei : Jurnal Hasil Kegiatan Pengabdian Masyarakat Indonesia
Publisher : FKIP, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59024/faedah.v1i2.301

Abstract

Dental health is part of overall health. Mother's level of knowledge has an important role in maintaining dental health in her child. Preschoolers are children aged between 4-6 years which is called the "golden age". So that in the preschool period mothers should have taught children how to brush their teeth properly. This service aims to provide education and increase mother's knowledge about brushing teeth to students of Perwanida Kindergarten, West Kotawaringin Regency, Central Kalimantan. This service is carried out by providing education to 50 mothers through speeches using visual aids about proper tooth brushing procedures. Measuring the level of knowledge was carried out using pretest and posttest questionnaires. Mother's knowledge level data were analyzed using MS.Excel and then translated into Good, Adequate, and Poor knowledge level categories. The results of this activity showed that there was an increase in mother's knowledge in the Good category from 53% to 74% and a decrease in mother's knowledge in the Enough category from 45% to 26% and in the Less category 2% to 0%. Based on the results of the education, it can be concluded that Education on the Use of Toothbrushes for Mothers of Perwanida Kindergarten students in West Kotawaringin, Central Kalimantan is said to be successful with an increase in the Good knowledge category. It is recommended that health workers can improve health promotion on how to brush their teeth properly in order to reduce the incidence of dental disease in children.
Pelatihan Pembuatan Biopeptisida untuk Peningkatan Ekonomi dan Sosial Warga Desa Efriyana Oksal; Zimon Pereiz; Shesanthi Citrariana; Chuchita Chuchita
Bubungan Tinggi: Jurnal Pengabdian Masyarakat Vol 6, No 1 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/btjpm.v6i1.10150

Abstract

Masyarakat pada umumnya menggunakan peptisida untuk memberantas hama ataupun penyakit tanaman tersebut. Jumlah pestisida yang digunakan dalam jumlah yang banyak, lama kelamaan akan memiliki dampak negatif bagi kesehatan dan juga merusak lingkungan. Sehingga perlu dilakukan program pelatihan pembuatan biopeptisida ini, bagi warga di Desa Habaring Hurung, Kota Palangka Raya menjadi partisipan, karena sebagian besar warga berprofesi sebagai petani. Warga Desa Habaring Hurung, Kota Palangka Raya pada umumnya menggunakan peptisida kimia dalam praktek pemeliharaan tanaman dari serangan hama. Untuk mendukung warga desa Habaring Hurung dalam meningkatkan perekonomian dibuatlah pelatihan biopeptisida dari gulma babadotan. Program pengabdian Masyarakat ini bertujuan dapat membantu warga mengatasi gangguan dan serangan hama tumbuhan dengan biopeptisida alami yang lebih murah dan aman bagi kesehatan sehingga dapat meningkatkan hasil produksi dan menekan biaya pemeliharaan pertanian, sehingga meningkatkan segi ekonomi dan sosial warga desa Habaring Hurung, Kota Palangka Raya  yang dilaksanakan pada hari senin, 4 September 2023. Kegiatan ini dilaksanakan dengan metode praktik langsung pembuatan biopestisida dengan bahan utama gulma babadotan dan FGD (Focus Group Discussion). Hasil dari pelatihan ini, warga Habaring Hurung, mengetahui dampak negative dari peptisda kimia, biopeptisida sebagai alternatif dalam pembasmi hama dan warga dapat menginovasikan pembuatan biopeptisida dengan tanaman yang mengandung senyawa aktif terhadap hama. Melalui pelatihan ini warga di Kelurahan Habaring Hurung dapat mengganti biopestisida kimia berbahaya selama ini sering dipakai dengan menggunakan biopeptisida nabati yang tentunya aman bagi Kesehatan para petani dan juga ramah lingkungan.Agricultural products are one aspect that improves the economy for people in Indonesia. However, some pests reduce the quality of agricultural products, thereby reducing selling prices. People generally use pesticides to eradicate pests or plant diseases. Excessive and long-term use of pesticides has a negative impact on health and can damage the environment. In this training program for making biopesticides, Habaring Hurung Village, Palangka Raya residents became participants because most residents work as farmers. Residents of Habaring Hurung Village, Palangka Raya, generally use chemical pesticides to protect plants from pest attacks. To support the residents of Habaring Hurung village in improving the economy, training was conducted on biopesticides from babadotan weed. This community service program aims to help residents overcome plant pest disorders and attacks with natural biopesticides that are cheaper and safer for health so that they can increase production yields and reduce agricultural maintenance costs, thereby improving the economic and social aspects of the residents of Habaring Hurung village, Palangka Raya. This activity was carried out by making a biopesticide with the main ingredient babadotan weed and FGD (Focus Group Discussion). As a result of this training, Habaring Hurung residents know the negative impacts of chemical pesticides and biopesticides as an alternative for eradicating pests, and residents can innovate the manufacture of biopesticides with plants that contain active compounds against pests.
FORMULASI DAN UJI EFEKTIVITAS SEDIAAN GEL EKSTRAK DAUN BAJAKAH KALALAWIT (Uncaria gambir Roxb.) TERHADAP PROSES PENYEMBUHAN LUKA BAKAR PADA MENCIT PUTIH Ayuchecaria, Noverda; Yohanes Edy Gunawan; Efriyana Oksal; Shesanthi Citrariana
Jurnal Insan Farmasi Indonesia Vol 6 No 2 (2023): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i2.1635

Abstract

Burns are tissue loss caused by contact with heat sources. Burns will not only cause skin damage, but also affect the entire body system. Bajakah kalalawit contains polyphenolic compounds. This research aims to design a gel preparation formulation that is effective in the healing process of burn wounds in white mice. The preparation was also tested for its physicochemical characteristics including organoleptic test, homogeneity test, pH test, spreadability and stickiness test and irritation test. The results showed that all formulas were homogeneous and no organoleptic changes occurred after 14 days. The pH range of Bajakah gel is 6.16 – 7.46 which meets the skin's pH requirements. The diameter range of spreading power is between 5-7 cm. The adhesion power of formulas 2 and 3 meets the requirements (<4 seconds). The four formulas did not show irritation in the irritation test. The conclusion of this research is that Bajakah kalalawite extract gel with the composition of Formulas 2 and 3 meets the requirements for physical quality characteristic tests including organoleptic, homogeneity, pH, spreadability, adhesive power and irritation test. The diameter of the burn wound showed that there was a significant difference in treatment compared to the negative control group (p<5%).
ANALISIS KADAR ALKOHOL PADA OBAT BATUK SIRUP ANAK: VALIDASI METODE HALAL PRODUK Shesanthi Citrariana; Puspa Dwi Pratiwi; Yahya Febrianto
Jurnal Farmasi Medica/Pharmacy Medical Journal (PMJ) Vol. 7 No. 1 (2024): Volume 7, No 1, Tahun 2024
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pmj.v7i1.52860

Abstract

The global halal market, including halal food and beverage products, is expected to continue to grow widely. Halal food and drinks according to Islamic law have the criteria of being free from alcoholic, intoxicating and dangerous drinks as well as food additives containing derivatives of these drinks. There are many medicinal preparations circulating on the market that contain alcohol, one of which is cough medicine. This study aims to validate the method and measure alcohol levels in children's cough medicine taken randomly on the market. The method used is GC (Gas Chromatography) with validation determination in the form of linearity tests, system suitability tests, accuracy, LOD and LOQ calculations. The results of this study show that the linearity is R = 0.998. In the system suitability test, the chromatographic N value was >1000, HETP <0.3, and R >1.5. The accuracy obtained is in the range 81.13% - 123.57%. The LOD value is 0.1106% and LOQ is 0.3352%. As well as alcohol residue found in cough medicine samples of 0.075%. From these results it can be concluded that the GC (Gas Chromatography) method used has good validity and the residual alcohol content in children's cough medicine preparations meets the BPOM and MUI halal requirements. Keywords: Gas Cromatography, validation, halal, medicine
Pendampingan Izin CPKB Industri Kosmetik Golongan B UMKM CV Bawi Bakena di Kota Palangka Raya Shesanthi Citrariana; Guntur Satrio Pratomo; Ardi Akbar Tanjung
Faedah : Jurnal Hasil Kegiatan Pengabdian Masyarakat Indonesia Vol. 2 No. 2 (2024): Jurnal Hasil Kegiatan Pengabdian Masyarakat Indonesia
Publisher : FKIP, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59024/faedah.v2i2.836

Abstract

CV Bawi Bakena UMKM is the only herbal cosmetics producer in Palangka Raya City, but has not yet met the legal requirements for the class B cosmetics industry. The aim of this service activity is to provide effective assistance in obtaining a CPKB certificate so that CV Bawi Bakena cosmetics producing UMKM can obtain legality. product. in supporting the micro economy in the city of Palangka Raya. The mentoring model used is the PRA (Participatory Rural Appraisal) approach, where service providers and the community are directly involved in optimizing all existing potential. This service activity uses two stages, namely: the process of repairing building floors and workshops to obtain a class B industrial CPKB permit. The results of the service carried out show progress in fulfilling the submission requirements documents such as the issuance of plan approval from BPOM RI and completeness of production documents for the CPKB permit such as raw material documents, product packaging documents and industrial waste management. Palangka Raya, as a city that has plant biodiversity, has the opportunity to make herbal cosmetics a regional superior product.
Co-Authors Adi, Mika Akhmad Kharis Nugroho Alfanaar, Rokiy Ardi Akbar Tanjung Ari Wibowo Arsana, Mu afa Arsana, Mu’afa Purwa Arsana, Mu’afa Purwa Awalul Fatiqin Awumistiko Awumistiko Ayu, Regina Wahyudyah Sonata Ayuchecaria, Noverda Baiq Maylinda Gemantari Bambang Hernawan Nugroho Chuchita Dea Betriksia Decenly Decenly Decenly, Decenly Defilia Anogra Riani Defilia Anograh Riani Desindria, Galang Rizdho Efriyana Oksal Efriyana Oksal Emma Ayudia Noriadita Endang Lukitaningsih Erni Dwi Puji Setyowati, Erni Dwi Puji Fatiqin, Awalul Fauziah, Anisa Rahma Gerung, Jenny Blessia Gintoro, Atilla Dian Dewanti Gunawan, Yohanes E Gunawan, Yohanes Edy Guntur Satrio Pratomo Halida Suryadini Haq, Muhammad Hasanul Ita Nurma Sari Ita Nurma Sari Jipasca, Elon Kalalinggi, Septaria Yolan Krissilvio, Eka Jonathan M Munawwarah Ma'rifah, Siti Mariasa, Joice Cleriska Melliani Melliani Muhammad Dawam Muhammad Priyadi Mu’afa Purwa Arsana Mu’afa Purwa Arsana Ngazizah, Febri Nur Nur Hidayat Oktavia Indrati, Oktavia Parametta, Vidya Puspa Dwi Pratiwi Puspa Dwi Pratiwi Rahman, Ansori Rahman, Sudarman Reny Nadya Oktari Riani, Defilia Rika Arfiana Safitri Risqika Yulia Tantri Paramawidhita Rizki Rachmad Saputra Rokiy Alfanaar Shodri, Muhammad Rifqi Simajuntak, Ruth Riama Siti Sunariyati Solikha, Sisi Sulistia, Tiya Thathit Suprayogi Tri Megawati Wahyu Nugroho Wilda, Robiatul Witari Yahya Febrianto Yahya Febrianto Yehezkiel Steven Kurniawan Yohanes Edy Gunawan Yosaeunike, Vitatani Yulita, Elia Zimon Pereiz