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Determinasi Kejadian Perilaku Seksual Pranikah dalam Aktivitas Pacaran Remaja di Kalimantan Tengah Shesanthi Citrariana; Risqika Yuliatantri Paramawidhita; Halida Suryadini; Muhammad Dawam; Awumistiko Awumistiko
Jurnal Surya Medika (JSM) Vol 7 No 1 (2021): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v7i1.2232

Abstract

Based on the 2017 IDHS survey, most adolescent women (80%) and men (84%) reported dating. The 15-17 years is the age group when adolescents start dating. Teenage dating activities lead to sexual behavior, such as holding hands, hugging, kissing lips, touching sensitive parts, and having sex. This study aims to determine the influence of the background characteristics of adolescents (age, area of residence, level of education) and social patterns (having friends having premarital sex, having the urge because of friends, influencing friends to have premarital sex, considering virginity important) on the incidence of premarital sex in Central Kalimantan 2017. Secondary data were obtained from the 2017 IDHS survey. Data analysis was performed by univariate, bivariate (Spearman rho test), and multivariate (logistic regression test). The results showed that 88% of respondents had sexual behavior orientation, and 12% did not. The correlation analysis explains a significant relationship between premarital sexual behavior and the area of residence. Respondents who live in cities are 3.47 times more likely to commit premarital sexual behavior (α<0,05 = 0,021; OR = 3.47). In addition, there is sufficient evidence to suggest a relationship between premarital sexual behavior and education level, respondents who attend high school and above are 2.71 times more likely to have premarital sexual behavior (α<0,10 = 0,066; OR = 2.71). Meanwhile, other variables from background characteristics and social patterns have no significant relationship/do not influence premarital sexual behavior. So it can be concluded that the background characteristics in the area of residence (Sig Wald <0.0) have a significant partial effect on adolescents' incidence of premarital sexual behavior in Central Kalimantan.
Formulasi dan evaluasi SNEDDS (Self Nanoemulsifying Drug Delivery System) ekstrak daun pepaya (Carica papaya L.) sebagai analgesik Bambang Hernawan Nugroho; Shesanthi Citrariana; Ita Nurma Sari; Reny Nadya Oktari; M Munawwarah
Jurnal Ilmiah Farmasi Vol. 13 No. 2 (2017): Jurnal Ilmiah Farmasi
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.vol13.iss2.art5

Abstract

Intisari Latar belakang: SNEDDS dipilih karena dapat meningkatkan absorbsi obat yang memiliki kelarutan rendah didalam air seperti zat aktif yang berasal dari ekstrak tanaman.Tujuan: Penelitian ini bertujuan untuk membuat suatu inovasi sediaan obat dengan memanfaatkan sistem penghantaran obat baru yang berupa Self Nanoemulsifiying Drug Delivery System (SNEDDS)menggunakan zat aktif ekstrak daun papaya (Carica Papaya L.) yang berkhasiat sebagai analgesik.Metode: SNEDDS ekstrak daun pepaya Carica Papaya L.) dibuat dengan metode high energy. ekstraksi dilakukan dengan metode maserasi daun yang telah dikeringkan menggunakan etanol 96% kemudian ekstrak diuapkan dengan rotary evaporator hingga menjadi ekstrak pekat dan ditambahkan kedalam formulasi. Sediaan SNEDDS dibuat 4 formula dengan fase minyak isopropil miristat, surfaktan PEG 400, dan kosurfaktan tween 80 menggunakan teknik high energy. Evaluasi terhadap sediaan berupa ukuran partikel, persen transmitan, dan freeze thawing. Formulasi SNEDDS yang memiliki kesesuaian parameter evaluasi akan dilakukan pengujian terhadap aktivitas analgesiknya secara in vivo menggunakan mencit galur balb-c yang diinduksi asam asetat 1% kemudian hasil uji dibandingkan dengan aktivitas analgesik asam mefenamatHasil: Hasil uji memperlihatkan bahwa semua formula memiliki ukuran partikel <200nm dan persen transmitan >90%. Hasil uji aktivitas analgesik SNEDDS secara in-vivo menunjukan bahwa persen inhibisi nyeri rata-rata SNEDDS ekstrak daun pepaya adalah 94,55%.Kesimpulan: Formula SNEDDS ekstrak daun pepaya dari F4 memenuhi parameter stabilitas yang baik dengan ukuran partikel yang paling kecil yaitu 77,1 nm. Persen inhibisi nyeri dari SNEDDS ekstrak daun papaya pada mencit galur balb-c yang diinduksi asam asetat adalah 94,55%.Kata kunci : SNEDDS, Carica Papaya L., analgesik
Validasi Metode Analisis Matriks Patch Domperidon Maleat dengan Perbedaan Polimer Menggunakan Spektorfotometri UV-Vis Shesanthi Citrariana; Oktavia Indrati; Puspa Dwi Pratiwi; Ita Nurma Sari; Ari Wibowo
Pharmacon: Jurnal Farmasi Indonesia Vol 18, No 2 (2021)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v18i2.14576

Abstract

Uv-Vis spectrophotometry is an analytical method that can be used to determine the levels of domperidon maleate contained in transdermal patches with different polymers. The analysis method needs to be validated to prove that it can provide measurement results that match its designation. The purpose of this study is to prove that uv-vis spectrophotometry methods can provide the specificity, linearity, thoroughness, and precision that meet the requirements. In this study, linearity was known by calculating the r value on the curve of the relationship between levels and absorbance. Precision is obtained based on rsd value. Accuracy is calculated based on the return value. Selectiveity is known by means of identity confirmation that calculates the absorbance ratio at different wavelengths. The results showed that the method meets the requirements with a value of r=0.999; RSD precision results at a level of 10 ppm obtained RSD 0.236%. The accuracy values of 80%, 100%, and 120% in the matrix of transdermal domperidon maleate patches with PVA and PVP polymers respectively recovery was 99.50%, 101.15%, and 99.13%.. In the matrix of transdermal patches domperidon maleate with polymers HPMC and Na-CMC respectively recovery was 100.91%, 100.31%, and 100.67%. In the matrix of transdermal domperidon patches with HPMC and EC polymers respectively recovery was 98.00%, 98.00%, and 99.00%. The identity confirmation results on the transdermal domperidon patch matrix with PVA and PVP polymers, HPMC and Na-CMC, as well as HPMC and EC respectively have ratio value close to the standard solution with an average value of 0.800; 0,806; and 0.808. It can be concluded that the method of analyzing the levels of domperidone maleate in matrix of transdermal patches has qualified for good validity.
Studi Perbandingan Disolusi In-Vitro Pada Formula Tablet Levofloksasin Immediate-Release Menggunakan Variasi Kadar Disintegran Sodium Starch Glycolate Shesanthi Citrariana; Endang Lukitaningsih; Akhmad Kharis Nugroho
Majalah Farmaseutik Vol 16, No 1 (2020)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (430.539 KB) | DOI: 10.22146/farmaseutik.v16i1.48941

Abstract

Levofloksasin merupakan antibiotik yang digunakan dalam terapi Community Acquired Pneumonia (CAP) dengan prevalensi cukup tinggi di Indonesia. Sodium starch glycolate (SSG) merupakan eksipien yang berfungsi sebagai disintegran. SSG direkomendasikan dalam formula tablet dengan konsentrasi 1-4% karena konsentrasi yang lebih tinggi dapat mengurangi kemampuan disintegrasinya. Kinetika pelepasan obat memiliki nilai yang sangat penting dalam pengembangan dan kontrol kualitas obat. Perubahan kualitatif dan kuantitatif eksipien dalam formula dapat mengubah kinetika pelepasan dan kinerja in-vivo. Peneliltian ini bertujuan untuk melakukan studi perbandingan kinetika pelepasan obat pada tablet levofloksasin yang diformulasikan menggunakan berbagai konsentrasi SSG. Hasil penelitian ini memperlihatkan bahwa konsentrasi SSG 1,33-5,33% dalam formula tidak memberikan perbedaan model kinetika pelepasan obat. Hal ini terlihat dari nilai f1 (3,12-8,50) dan f2 (56,16-77,43) yang berada pada rentang kriteria. Tablet levofloksasin Immediate-release (IR) yang diformulasikan, mengikuti pemodelan First-Order kinetik dengan kriteria nilai R2_adj tertinggi, MSE dan AIC terkecil, serta MSC terbesar dibandingkan dengan model kinetika lainnya. Pemodelan menggunakan Korsmeyer-Peppas memperlihatkan bahwa mekanisme transport dari tablet levofloksasin mengikuti persamaan Fickian semu (n<0,5) sehingga menggambarkan pelepasan obat dari matriks non-swellable.
EDUKASI “PENOL” (PENYEMARAK ESSENTIAL OIL) DAN PELATIHAN PRODUK SEDIAAN GUNA KESEHATAN BAGI KOMUNITAS MILENIAL DI KOTA PALANGKARAYA: Education "Penol" (Enlivening Essential Oil) and Training on Dosage Products for Health for the Millennial Community in Palangkaraya City Risqika Paramawidhita; Halida Suryadini; Shesanthi Citrariana
J-Dinamika : Jurnal Pengabdian Masyarakat Vol 7 No 3 (2022): Desember
Publisher : Politeknik Negeri Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25047/j-dinamika.v7i3.3300

Abstract

Essential Oil memiliki multimanfaat yang baik untuk digunakan dalam sediaan aromaterapi. Seiring perkembangan zaman dengan teknologi semakin canggih sehingga mendukung maraknya pemakaian produk-produk yang dikenal dengan “Back To Nature” salah satunya dengan mengangkat pamor dari essential oil terutama produk untuk kesehatan, dikarenakan dengan menggunakan minyak jenis ini akan memberi rasa relaksasi pada tubuh. Kaum millenial merupakan generasi maju sebagai contoh permodelan di masyarakat dan menjadi mitra yang akan mendukung untuk menyemarakkan penggunaan essential oil. Hal ini merupakan faktor penting dilakukan kegiatan pengabdian masyarakat tentang pelatihan pembuatan sediaan aromaterapi berbahan essential oil  kepada sekelompok komunitas milenial di kota Palangka Raya. Kegiatan ini diawali dengan pemberian edukasi dan menambah ketertarikan tentang essential oil, pelatihan pembuatan sediaan aromaterapi, serta di akhiri dengan evaluasi kegiatan pengabdian masyarakat dilakukan dengan pemberian pre dan post test dalam bentuk kuisioner. Hasil kegiatan yang didapatkan ialah adanya peningkatan pengetahuan, ketertarikan dan ketrampilan membuat sediaan aromaterapi bagi pihak mitra serta dapat menjadi inspirasi untuk dapat menyemarakkan potensi dari essential oil dalam mewujudkan komunitas milenial yang kreatif dan inovatif.
Gambaran Penjualan Obat Swamedikasi di Apotek Karomah Palangka Raya saat Pandemi Covid-19 Tahun 2021 Shesanthi Citrariana; Risqika Yuliatantri Paramawidhita
Sinteza Vol. 3 No. 1 (2023): February
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/sinteza.v3i1.7843

Abstract

Swamedikasi diartikan sebagai pemilihan dan pemanfaatan obat-obatan untuk mengobati gejala atau penyakit yang dikenali sendiri. Provinsi Kalimantan Tengah memiliki prevalensi swamedikasi yang tinggi yaitu 89,46%. Peningkatan minat masyarakat terhadap swamedikasi meningkat karena pandemi COVID-19. Penelitian ini bertujuan untuk melihat gambaran penjualan obat swamedikasi di Apotek Karomah saat pandemi COVID- 19 berlangsung. Pengumpulan data penjualan dilakukan dengan melihat pada SIM (Sistem Informasi Management) berbasis computer pada Juli – Agustus 2021. Hasil penelitian menunjukan bahwa tiga besar penjualan berdasarkan jenis obat di Apotek Karomah berupa Batuk&Flu sebanyak 1956 item (24,48%), Jamu&Minuman sebanyak 1482 item (18,55%), dan Alkes sebanyak 993 item (12,43%). Penjualan sepuluh besar (Top 10) berdasarkan item/ merk obat ditempati oleh komix batuk sebanyak 1236 item, madu TJ sebanyak 718 item, dan masker sebanyak 554 item. Total omzet penjualan pada Bulan Juli adalah Rp 49.068.000,- dan terlihat menurun pada Bulan Agustus Rp 43.944.000,-. Dari hasil penelitian ini dapat disimpulkan bahwa pandemi COVID-19 memberikan dampak penjualan obat swamedikasi di Apotek Karomah Kota Palangka Raya terutama obat-obat yang berkaitan dengan penurunan gejala COVID-19 dan peningkatan imunitas tubuh. 
Bahan Tambahan dalam Sediaan Tablet: Review Puspa Dwi Pratiwi; Shesanthi Citrariana; Baiq Maylinda Gemantari
Sinteza Vol. 3 No. 2 (2023): August
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/sinteza.v3i2.17472

Abstract

Tablets are solid pharmaceutical dosage form without or with suitable excipients by press or compression manufacturing process. The excipient chosen can influence the product performance (physical properties and stability) and bioavailability. All excipients must be optimally selected to get the optimal formula of tablet dosage form. This article review aims to overview of excipient in tablet dosage form and their role in formulating tablet dosage form. this review article was written based on literature studies from electronic databases such as PubMed, ScienceDirect, and Google Scholar which contain related information using keyword in Indonesian or English use article published in 2013-2023. excipients in tablet dosage form are fillers or diluents, disintegrants, lubricants, preservatives, flavors, sweeteners, coloring, and coating agents. These excipients added to tablet dosage form to facilitating the process of manufacture tablet dosage form, increasing stability and effectiveness of active pharmaceutical ingredients in tablet. The conclusion of this review, there are many classification of tablet excipients which is different function to get compendial requirements of tablet dosage form.
Edukasi Cara Sikat Gigi Pada Ibu Siswa TK Perwanida Kotawaringin Barat Kalimantan Tengah Shesanthi Citrariana; Tri Megawati
Faedah : Jurnal Hasil Kegiatan Pengabdian Masyarakat Indonesia Vol. 1 No. 2 (2023): Mei : Jurnal Hasil Kegiatan Pengabdian Masyarakat Indonesia
Publisher : FKIP, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59024/faedah.v1i2.301

Abstract

Dental health is part of overall health. Mother's level of knowledge has an important role in maintaining dental health in her child. Preschoolers are children aged between 4-6 years which is called the "golden age". So that in the preschool period mothers should have taught children how to brush their teeth properly. This service aims to provide education and increase mother's knowledge about brushing teeth to students of Perwanida Kindergarten, West Kotawaringin Regency, Central Kalimantan. This service is carried out by providing education to 50 mothers through speeches using visual aids about proper tooth brushing procedures. Measuring the level of knowledge was carried out using pretest and posttest questionnaires. Mother's knowledge level data were analyzed using MS.Excel and then translated into Good, Adequate, and Poor knowledge level categories. The results of this activity showed that there was an increase in mother's knowledge in the Good category from 53% to 74% and a decrease in mother's knowledge in the Enough category from 45% to 26% and in the Less category 2% to 0%. Based on the results of the education, it can be concluded that Education on the Use of Toothbrushes for Mothers of Perwanida Kindergarten students in West Kotawaringin, Central Kalimantan is said to be successful with an increase in the Good knowledge category. It is recommended that health workers can improve health promotion on how to brush their teeth properly in order to reduce the incidence of dental disease in children.
Pelatihan Pembuatan Biopeptisida untuk Peningkatan Ekonomi dan Sosial Warga Desa Efriyana Oksal; Zimon Pereiz; Shesanthi Citrariana; Chuchita Chuchita
Bubungan Tinggi: Jurnal Pengabdian Masyarakat Vol 6, No 1 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/btjpm.v6i1.10150

Abstract

Masyarakat pada umumnya menggunakan peptisida untuk memberantas hama ataupun penyakit tanaman tersebut. Jumlah pestisida yang digunakan dalam jumlah yang banyak, lama kelamaan akan memiliki dampak negatif bagi kesehatan dan juga merusak lingkungan. Sehingga perlu dilakukan program pelatihan pembuatan biopeptisida ini, bagi warga di Desa Habaring Hurung, Kota Palangka Raya menjadi partisipan, karena sebagian besar warga berprofesi sebagai petani. Warga Desa Habaring Hurung, Kota Palangka Raya pada umumnya menggunakan peptisida kimia dalam praktek pemeliharaan tanaman dari serangan hama. Untuk mendukung warga desa Habaring Hurung dalam meningkatkan perekonomian dibuatlah pelatihan biopeptisida dari gulma babadotan. Program pengabdian Masyarakat ini bertujuan dapat membantu warga mengatasi gangguan dan serangan hama tumbuhan dengan biopeptisida alami yang lebih murah dan aman bagi kesehatan sehingga dapat meningkatkan hasil produksi dan menekan biaya pemeliharaan pertanian, sehingga meningkatkan segi ekonomi dan sosial warga desa Habaring Hurung, Kota Palangka Raya  yang dilaksanakan pada hari senin, 4 September 2023. Kegiatan ini dilaksanakan dengan metode praktik langsung pembuatan biopestisida dengan bahan utama gulma babadotan dan FGD (Focus Group Discussion). Hasil dari pelatihan ini, warga Habaring Hurung, mengetahui dampak negative dari peptisda kimia, biopeptisida sebagai alternatif dalam pembasmi hama dan warga dapat menginovasikan pembuatan biopeptisida dengan tanaman yang mengandung senyawa aktif terhadap hama. Melalui pelatihan ini warga di Kelurahan Habaring Hurung dapat mengganti biopestisida kimia berbahaya selama ini sering dipakai dengan menggunakan biopeptisida nabati yang tentunya aman bagi Kesehatan para petani dan juga ramah lingkungan.Agricultural products are one aspect that improves the economy for people in Indonesia. However, some pests reduce the quality of agricultural products, thereby reducing selling prices. People generally use pesticides to eradicate pests or plant diseases. Excessive and long-term use of pesticides has a negative impact on health and can damage the environment. In this training program for making biopesticides, Habaring Hurung Village, Palangka Raya residents became participants because most residents work as farmers. Residents of Habaring Hurung Village, Palangka Raya, generally use chemical pesticides to protect plants from pest attacks. To support the residents of Habaring Hurung village in improving the economy, training was conducted on biopesticides from babadotan weed. This community service program aims to help residents overcome plant pest disorders and attacks with natural biopesticides that are cheaper and safer for health so that they can increase production yields and reduce agricultural maintenance costs, thereby improving the economic and social aspects of the residents of Habaring Hurung village, Palangka Raya. This activity was carried out by making a biopesticide with the main ingredient babadotan weed and FGD (Focus Group Discussion). As a result of this training, Habaring Hurung residents know the negative impacts of chemical pesticides and biopesticides as an alternative for eradicating pests, and residents can innovate the manufacture of biopesticides with plants that contain active compounds against pests.
FORMULASI DAN UJI EFEKTIVITAS SEDIAAN GEL EKSTRAK DAUN BAJAKAH KALALAWIT (Uncaria gambir Roxb.) TERHADAP PROSES PENYEMBUHAN LUKA BAKAR PADA MENCIT PUTIH Ayuchecaria, Noverda; Yohanes Edy Gunawan; Efriyana Oksal; Shesanthi Citrariana
Jurnal Insan Farmasi Indonesia Vol 6 No 2 (2023): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i2.1635

Abstract

Burns are tissue loss caused by contact with heat sources. Burns will not only cause skin damage, but also affect the entire body system. Bajakah kalalawit contains polyphenolic compounds. This research aims to design a gel preparation formulation that is effective in the healing process of burn wounds in white mice. The preparation was also tested for its physicochemical characteristics including organoleptic test, homogeneity test, pH test, spreadability and stickiness test and irritation test. The results showed that all formulas were homogeneous and no organoleptic changes occurred after 14 days. The pH range of Bajakah gel is 6.16 – 7.46 which meets the skin's pH requirements. The diameter range of spreading power is between 5-7 cm. The adhesion power of formulas 2 and 3 meets the requirements (<4 seconds). The four formulas did not show irritation in the irritation test. The conclusion of this research is that Bajakah kalalawite extract gel with the composition of Formulas 2 and 3 meets the requirements for physical quality characteristic tests including organoleptic, homogeneity, pH, spreadability, adhesive power and irritation test. The diameter of the burn wound showed that there was a significant difference in treatment compared to the negative control group (p<5%).