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Analisis Risiko Kadar Enzim SGOT dan SGPT pada Penderita Diabetes Mellitus Tipe 2 Mochamad Rizal Maulana; Sutji Kuswarini
Jaringan Laboratorium Medis Vol 4, No 1 (2022): May 2022
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v4i1.8489

Diabetes mellitus is a group of metabolic diseases that occur due to abnormalities in insulin secretion and/or insulin action. In type 2 diabetes mellitus there is a decrease in glucose absorption by the body due to insulin resistance. Energy metabolism from glucose is processed through the synthesis of fatty acids in the liver (cytosol). The process that occurs continuously causes the accumulation of lipids in the liver or "fatty liver" so it is necessary to check the levels of transaminase enzymes which include SGOT and SGPT. The purpose of this study was to analyze the levels of SGOT and SGPT enzymes in patients with type 2 diabetes mellitus using the analytical observational method. The results of the examination of SGOT and SGPT levels from 30 patients who were taken randomly at Dr. Soetomo Surabaya will be analyzed with bar graphs and diagrams. Of 30 random samples, 20 samples (66.67%) had SGOT levels above the normal value, and 12 samples (40%) had SGPT with results above normal values. This study concludes that there is an increase in the levels of SGOT and SGPT enzymes in patients with type 2 diabetes mellitus.

Hubungan Antara Kadar Asam Urat dengan Kepatuhan Minum Obat pada Pasien Tuberculosis Paru Qurrotu A'yuni Auliya; Mochamad Rizal Maulana; Djoko Priyatno
Jaringan Laboratorium Medis Vol 5, No 2 (2023): November 2023
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v5i2.9545

Tuberculosis lungs is disease infectious disease caused by bacteria Mycobacterium tuberculosis. TB disease still become threat health Indonesian society which leads to illness , disability and death tall so that need exists countermeasures. Research objectives know connection between rate sour tendon with obedience drink medication in pulmonary TB patients. Study This is study retrospective analytic observational with approach cross sectional, with use analysis Research Chi square test statistics conducted at the Ambarawa Community Health Center (BALKESMAS) in October 2022. Population all moderate pulmonary TB patients undergo treatment at BALKESMAS Ambarawa. Research sample This of the total population namely 30 patients. Results from 30 respondents there is rate sour veins in patients Tuberculosis lungs there is enhancement rate sour tendon namely 11 respondents that is man with average levels sour urate 7.08 mg/dL (6 respondents ), female with average level 6.41 mg/dL (5 respondents ). Based on forever drink drug obtained that amount patient with treatment 3 months 57%, 2-3 months 30%, and 1 month 13%. Based on characteristics that kind sex men 53% and kind sex women 47%. Based on characteristics age category teenagers 23%, adults 50% elderly 27%. Based on obedience drink anti-tuberculosis drugs by 28 respondents or 93.34% of total number of respondents . Whereas For respondents who did not obedient drink drug namely 2 respondents or 6.06%. Chi square test results on compliance status drink medicine, type gender, age No showing connection significant (P0.05) against rate sour veins in patients Tuberculosis lungs. Research conclusions This No There is connection rate sour tendon with obedience drink medication in pulmonary TB patients, This caused by TB Treatment consists of over 2 stages that is intensive and advanced, function system immunity body relate with age, history of medication, obesity, consumption purines , and alcohol.

Profil SGOT, SGPT, dan Kreatinin Pada Pasien MDR TB di RS KRMT Wongsonegoro Semarang Surati, Surati; Khairunnisa, Afifah; Setyaji, Yoki; Maulana, Mochamad Rizal
Jaringan Laboratorium Medis Vol 6, No 1 (2024): May 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v6i1.10951

Tuberculosis (TB) is an infectious disease caused by infection with the bacterium Mycobacterium tuberculosis. Tuberculosis apabila is not treated immediately or the treatment is not complete can result in complications leading to death. Multidrugs resistant tuberculosis (MDR-TB) is one of the complications where the germ Mycobacterium tuberculosis can no longer bekilled with several Anti-Tuberculosis Drugs (OAT). The prevalence of MDR-TB cases in Semarang City has increased from 35 cases in 2017 to 79 cases in 2018. MDR-TB therapy takes a longer time, which is about 18-24 months. Prolonged exposure to drugs can affect body functions, especially the kidneys and liver organs which play a role in the process of removing toxins and metabolic waste. This study aims to determine the health profile of the kidney and liver organs of MDR TB sufferers through the SGOT SGPT and Creatinine parameters and describe them based on age and age range. This research is adescriptive quantitative research with a cross-sectional approach. Sampling using total samples of 18 patients. The results showed that 33% (n= 6) of patients had increased levels of SGOT and SGPT, while examination of creatinine levels showed that 33% of patients had kidney problems. Men have upnormal SGOT and SGPT levels of 40% ( n=4) compared to women, which is 25% (n=2), while upnormal creatinine levels in men are 40% (n=4) while in women it is 50% (n = 8). Patients over the age of 46 years have the most levels of SGOT SGPT and upnormal creatinine, which is 61% (n=4). The results showed that age and gender had an effect on increasing SGOT SGPT and Creatinine levels in MDR-TB patients.

Analisis Risiko Kadar Enzim SGOT dan SGPT pada Penderita Diabetes Mellitus Tipe 2 Maulana, Mochamad Rizal; Kuswarini, Sutji
Jaringan Laboratorium Medis Vol. 4 No. 1 (2022): May 2022
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v4i1.8489

Diabetes mellitus is a group of metabolic diseases that occur due to abnormalities in insulin secretion and/or insulin action. In type 2 diabetes mellitus there is a decrease in glucose absorption by the body due to insulin resistance. Energy metabolism from glucose is processed through the synthesis of fatty acids in the liver (cytosol). The process that occurs continuously causes the accumulation of lipids in the liver or "fatty liver" so it is necessary to check the levels of transaminase enzymes which include SGOT and SGPT. The purpose of this study was to analyze the levels of SGOT and SGPT enzymes in patients with type 2 diabetes mellitus using the analytical observational method. The results of the examination of SGOT and SGPT levels from 30 patients who were taken randomly at Dr. Soetomo Surabaya will be analyzed with bar graphs and diagrams. Of 30 random samples, 20 samples (66.67%) had SGOT levels above the normal value, and 12 samples (40%) had SGPT with results above normal values. This study concludes that there is an increase in the levels of SGOT and SGPT enzymes in patients with type 2 diabetes mellitus.

Hubungan Antara Kadar Asam Urat dengan Kepatuhan Minum Obat pada Pasien Tuberculosis Paru Auliya, Qurrotu A'yuni; Maulana, Mochamad Rizal; Priyatno, Djoko
Jaringan Laboratorium Medis Vol. 5 No. 2 (2023): November 2023
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v5i2.9545

Tuberculosis lungs is disease infectious disease caused by bacteria Mycobacterium tuberculosis. TB disease still become threat health Indonesian society which leads to illness , disability and death tall so that need exists countermeasures. Research objectives know connection between rate sour tendon with obedience drink medication in pulmonary TB patients. Study This is study retrospective analytic observational with approach cross sectional, with use analysis Research Chi square test statistics conducted at the Ambarawa Community Health Center (BALKESMAS) in October 2022. Population all moderate pulmonary TB patients undergo treatment at BALKESMAS Ambarawa. Research sample This of the total population namely 30 patients. Results from 30 respondents there is rate sour veins in patients Tuberculosis lungs there is enhancement rate sour tendon namely 11 respondents that is man with average levels sour urate 7.08 mg/dL (6 respondents ), female with average level 6.41 mg/dL (5 respondents ). Based on forever drink drug obtained that amount patient with treatment >3 months 57%, 2-3 months 30%, and 1 month 13%. Based on characteristics that kind sex men 53% and kind sex women 47%. Based on characteristics age category teenagers 23%, adults 50% elderly 27%. Based on obedience drink anti-tuberculosis drugs by 28 respondents or 93.34% of total number of respondents . Whereas For respondents who did not obedient drink drug namely 2 respondents or 6.06%. Chi square test results on compliance status drink medicine, type gender, age No showing connection significant (P<0.05) against rate sour veins in patients Tuberculosis lungs. Research conclusions This No There is connection rate sour tendon with obedience drink medication in pulmonary TB patients, This caused by TB Treatment consists of over 2 stages that is intensive and advanced, function system immunity body relate with age, history of medication, obesity, consumption purines , and alcohol.

Profil SGOT, SGPT, dan Kreatinin Pada Pasien MDR TB di RS KRMT Wongsonegoro Semarang Surati, Surati; Khairunnisa, Afifah; Setyaji, Yoki; Maulana, Mochamad Rizal
Jaringan Laboratorium Medis Vol. 6 No. 1 (2024): May 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v6i1.10951

Tuberculosis (TB) is an infectious disease caused by infection with the bacterium Mycobacterium tuberculosis. Tuberculosis apabila is not treated immediately or the treatment is not complete can result in complications leading to death. Multidrugs resistant tuberculosis (MDR-TB) is one of the complications where the germ Mycobacterium tuberculosis can no longer bekilled with several Anti-Tuberculosis Drugs (OAT). The prevalence of MDR-TB cases in Semarang City has increased from 35 cases in 2017 to 79 cases in 2018. MDR-TB therapy takes a longer time, which is about 18-24 months. Prolonged exposure to drugs can affect body functions, especially the kidneys and liver organs which play a role in the process of removing toxins and metabolic waste. This study aims to determine the health profile of the kidney and liver organs of MDR TB sufferers through the SGOT SGPT and Creatinine parameters and describe them based on age and age range. This research is adescriptive quantitative research with a cross-sectional approach. Sampling using total samples of 18 patients. The results showed that 33% (n= 6) of patients had increased levels of SGOT and SGPT, while examination of creatinine levels showed that 33% of patients had kidney problems. Men have upnormal SGOT and SGPT levels of 40% ( n=4) compared to women, which is 25% (n=2), while upnormal creatinine levels in men are 40% (n=4) while in women it is 50% (n = 8). Patients over the age of 46 years have the most levels of SGOT SGPT and upnormal creatinine, which is 61% (n=4). The results showed that age and gender had an effect on increasing SGOT SGPT and Creatinine levels in MDR-TB patients.

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