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UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL AKAR BAJAKAH TAMPALA (Spatholobus Littoralis Hassk) MENGGUNAKAN METODE PEREDAMAN RADIKAL BEBAS DPPH Sari, Wina Astri; Tahir, Masdiana; Baits, Muzakkir
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 3 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i3.271

Abstract

Bajakah tampala (Spatholobus littoralis Hassk.) is a plant that lives on vines in tropical areas. This plant comes from Sebuku Village, North Kalimantan. The Bajakah Tampala plant contains saponins, flavonoids and tannins. The roots of the Bajakah Tampala plant are thought to have strong antioxidant activity which is able to reduce the activity of free radicals. The aim of this research is to analyze the antioxidant activity of Bajakah Tampala roots using the DPPH reduction method using a UV Vis spectrophotometer which is based on calculating the IC50 value. The results of this study indicate that the ethanol extract of Bajakah Tampala roots has antioxidant activity against DPPH free radicals with an IC50 value of 9.206 µg/mL. which is included in the group of very strong antioxidants.
Perbandingan Kadar Perbandingan Kadar Fenolik Ekstrak Daun Karet Kebo (Ficus elastica) Hasil Ekstraksi Bertingkat Menggunakan Metode Spektrofotometri UV-Vis mondo, zhafira anggraini; Suhaenah, Asriani; Tahir, Masdiana
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 3 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i3.278

Abstract

ZHAFIRA ANGGRAINI MONDO. Comparison of Phenolic Content of Rubber Kebo (Ficus elastica) Leaf Extract Results from Multilevel Extraction Using the UV-Vis Spectrophotometry Method (Supervised by Asriani Suhaenah and Masdiana Tahir). The kebo rubber plant (Ficus elastica) is used by Indonesian people as traditional medicine, namely medicine to lower blood pressure, lower cholesterol, stroke, and reduce joint pain. Kebo rubber leaves (Ficus elastica) contain secondary metabolites such as saponins, polyphenols, flavonoids and tannins. This research aims to determine the comparison of phenolic compound levels of kebo rubber leaf extract (Ficus elastica) resulting from multilevel extraction using the UV-vis spectrophotometric method. The extraction process uses 3 different types of solvents, namely n-hexane (nonpolar), ethyl acetate (semipolar) and ethanol (polar) using a sonicator. Determination of phenolic content using the UV-Vis spectrophotometric method, with a maximum wavelength of 772 nm and using gallic acid as a comparison. The results showed that the levels were influenced by the solvent used in comparing the phenolic compound levels of kebo rubber leaf extract (Ficus elastica) with the multilevel extraction method, namely n-hexane extract 3,774 mgGAE/g, ethyl acetate extract 12,696 mgGAE/g, ethanol extract 74,396 mgGAE/g g.
Comparasion Of Levels Perbandingan Kadar Flavonoid Ekstrak Daun Karet Kebo (Ficus elastica)Hasil Ekstraksi Bertingkat Menggunaka evatiara, nur; Suhaenah, Asriani; Tahir, Masdiana
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 3 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i3.282

Abstract

NUR EVATIARA. Comparison of flavonoid levels of rubber plant leaf extract (Ficus elastica) resulting from multilevel extraction using the UV-Vis spectrophotometric method. (Supervised by Asriani Suhaenah and Masdiana Tahir). Rubber plant (Ficus elastica) is a plant in the Moraceae family whose leaves have been empirically stated to contain secondary metabolite compounds such as saponins, polyphenols, flavonoids and tannins which have been used as medicine for coughing up blood, improving urine flow, relieving pain and improving blood circulation. The aim of this research was to determine the comparison of levels of flavonoid compounds in rubber plant leaf extract (Ficus elastica) resulting from multilevel extraction using the UV-Vis spectrophotometric method. The multistage extraction process uses 3 different types of solvents, namely n-hexane (nonpolar), ethyl acetate (semipolar), and ethanol (polar) using a sonicator. Determination of flavonoid levels using the UV-Vis spectrophotometric method, with a maximum wavelength of 432 nm and quarcetin as a comparison. The research results were influenced by the solvent used in comparing the levels of flavonoid compounds, namely rubber plant leaf extract (Ficus elastica) with a multilevel extraction method, namely N-hexane extract 7.161 mgQE/g, Ethyl acetate extract 7.663 mgQE/g, 96% Ethanol extract 10.592 mgQE/g g.
Sulfonamide Residue in the Broiler Chicken Circulating in Makassar Fawwaz, Muammar; Razak, Rais; Tahir, Masdiana; Permatasari, Andi; Amula, Andi Tenri; Seniwati, Seniwati
Pharmaceutical Reports Vol 1, No 2 (2022): (October) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (443.376 KB) | DOI: 10.33096/pharmrep.v1i2.169

Abstract

The use of sulfonamide related to drug residual in the product of broiler chicken, like meat and egg. This research aimed to determine the sulfonamides (sulfamerazine, sulfanilamide, and sulfadiazine) on the broiler chicken meat, breast, and egg from the three different slaughterhouses circulating in the City of Makassar. The sample was extracted by acetonitrile and acetone then concentrated. The extract and sulfonamides then analyzed by HPLC method using C18 reverse phased column, UV-Visible detector in the wavelength of 270 nm. The result of study shows that the chromatogram of sample breast and egg has similar retention time with sulfonamides as a standard reference. The breast sample contains sulfamerazine residues, sample B and C contains 0.014 and 0.005 % (w/w), respectively. The egg sample A and D contains sulfadiazine 0.045 and 0.108 % (w/w), respectively. Sample B contains sulfanilamide 0.053 % (w/w). Sample A and B is egg yolk, while sample D is egg whites. Based on the results obtained, this is not suitable for the rules set by JECFA of 0.1 mg/kg (10-5 % w/w) as well as the standard of SNI. It can be concluded that generally broiler chicken breast and egg circulating in the City of Makassar was contaminated by sulfonamide with high concentration.
Determination of Total Phenolic Levels of Ethyl Acetate Fraction of Clove Leaves (Syzygium aromaticum (L) Merr) Arniati, Arniati; Pratama, Mamat; Baits, Muzakkir; Tahir, Masdiana
Pharmaceutical Reports Vol 1, No 2 (2022): (October) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (193.887 KB) | DOI: 10.33096/pharmrep.v1i2.167

Abstract

Clove is a spice plant used in the kretek cigarette industry, food, beverage, and medicine. Clove leaves contain chemical compounds, namely saponins, flavonoids, tannins, and essential oils. The exploration of clove leaves has not been maximally carried out. Therefore, this study aims to determine the total phenolic content in the ethyl acetate fraction of clove leaves by using gallic acid as a comparison. Clove leaves were powdered and then macerated by ethanol. The ethanol extract was dissolved in distilled water and it was fractionated with ethyl acetate on a separating funnel. The method used in this assay is the UV-Vis spectrophotometry technique. The qualitative analysis was performed by adding the FeCl3 reagent. The results showed that the ethyl acetate fraction of clove leaves contained a total phenolic compound of 65.52 mg gallic acid equivalent per gram of extract (GAE/g). Thus, the ethyl acetate fraction of clove leaves is feasible to be developed as a source of phenolic compound.
PENYULUHAN PERILAKU HIDUP BERSIH DAN SEHAT (PHBS) DI SD INPRES BORISALLO KECAMATAN PARANGLOE KABUPATEN GOWA Tahir, Masdiana; Suhaenah, Asriani; Aminah, Aminah
Jurnal BALIRESO Vol 4, No 2 (2019)
Publisher : Lembaga Pengabdian kepada Masyarakat Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/balireso.v4i2.121

Abstract

The village of Borisallo is a Development Partner Village of UMI in Gowa Regency. One of theeducational facilities is SD Inpres Borisallo where a school is a place of learning that can be athreat of disease transmission if it is not managed properly. Problems with children's healthbehavior are usually related to personal and environmental hygiene. By that, the planting of valuesof health behavior in elementary schools is an absolute necessity and an effort to realize "Healthyand Independent Community" as contained in the health profile of Gowa Regency. As for studentsin SD Inpres Borisallo as many as 102 children with 9 teaching staff. Ideally, the health ofelementary school children is monitored by UKS, but due to various limitations, the role of theUKS SD Inpres Borisallo has not been implemented optimally and there is no special handwashing place for students. The target to be achieved is to increase students' knowledge,awareness, willingness and ability to live clean and healthy lives, and be expected to play an activerole in realizing optimal health degrees, instilling clean and healthy behavioral values (PHBS),improving the practice of handwashing with soap true and became a habit in the daily lives of SDInpres Borisallo students. The approach taken to achieve the target is to provide clean and healthylife behavior counseling (PHBS) and socialization of how to wash hands with soap properly andcorrectly, procure posters on how to wash hands and procure water tap pipe installationinfrastructure for hand washing needs in SD Inpres Borisallo students.
PKM PRODUKSI TEH HERBAL DARI KOMBINASI DAUN DAN BUNGA KERSEN (Muntingia calabura L.) PADA IBU PKK DI DESA PADDINGIN KAB. TAKALAR Masdiana Tahir; Asriani Suhaenah; Nurlina; Safruddin
JURNAL PENGABDIAN MASYARAKAT YAMASI Vol. 4 No. 2 (2025): Jurnal Pengabdian Masyarakat Yamasi
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/v47e7g03

Abstract

Tanaman kersen banyak tumbuh di daerah desa Paddingin Kec. Sanrobone, Kab.Takalar yang terlihat disepanjang jalan desa sebagai tanaman pelindung. Daun dan bunga kersen telah terbukti mengandung banyak senyawa kimia yang dapat memberikan aktivitas farmakologis seperti antidiabetes, antikolesterol, antibakteri, dan antioksidan, Berdasarkan hasil survei diketahui bahwa penyakit diabetes, kolesterol, asam urat dan tekanan darah merupakan penyakit yang masuk dalam 10 besar terbanyak yang diderita oleh masyarakat di desa Paddingin. Sehingga masyarakat perlu diedukasi cara penanganan dan pencegahannya dengan pemanfaatan tanaman kersen sebagai alternatif pengobatan tanpa menggunakan obat kimia yang memiliki efek samping. Tujuan PKM ini adalah untuk memberikan pengetahuan dan keterampilan IPTEK pembuatan teh herbal dari kombinasi daun dan bunga kersen pada mitra ibu PKK desa Paddingin. Pelaksanaan kegiatan PKM ini diawali dengan tahap pre test kemudian penyuluhan tentang manfaat kersen dan sediaan teh herbal. Selanjutnya dilakukanĀ  pelatihan cara membuat produk teh herbal dalam kantong teh celup dan dikemas dalam pouch yang diberi label agar bernilai komersial, yang dipraktekkan langsung oleh peserta. Tahap berikutnya adalah uji hedonik untuk mengukur tingkat kesukaan pada produk teh herbal yang telah dibuat dan diperoleh hasil 95% peserta memilih suka dan 5% memilih sangat suka dan 0% yang memilih agak suka dan tidak suka. Tahap terakhir evaluasi dengan melakukan post test dan tanya jawab. Hasil evaluasi menjukkan adanya peningkatan pengetahuan sebesar 75% dan keterampilan sebesar 100% dalam mengolah tanaman kersen dengan memanfaatkan daun peserta dan bunganya menjadi produk teh herbal yang bermanfaat bagi kesehatan. Dengan dilakukannya kegiatan PKM ini diharapkan ibu-ibu PKK desa Paddingin dapat membuat produk teh herbal dari kersen secara mandiri dirumah untuk kebutuhan pengobatan sendiri serta keluarga dan dapat memberi peluang wirausaha untuk membantu perekonomian keluarga.