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St. Maryam, St.
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Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Mathematics Mechanical Engineering Medicine & Pharmacology Physics Social Sciences Other

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Journal : Journal Microbiology Science

 1 
Antibacterial Activity in Ethanol Extract of Kersen Flowers (Muntingia calabura L.) Against Bacteria Causing Gastrointestinal Tract Infections Using the Agar Diffusion Method Maryam, St.; Fitriana, Fitriana; Annisa, Nurfiqah
Journal Microbiology Science Vol 4, No 2 (2024)
Publisher : Fakultas Farmasi, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jms.v4i2.1157

Abstract

The increasing prevalence of antibiotic resistance necessitates the exploration of alternative treatments such as medicinal plants. This study evaluates the antibacterial potential of Kersen flowers (Muntingia calabura L.) against pathogens causing gastrointestinal infections. Aimed at determining the antibacterial effectiveness of ethanol extracts from Kersen flowers, the research tests the activity against Escherichia coli, Salmonella typhi, Vibrio cholerae, and Shigella dysenteriae. Employing the agar diffusion method, various concentrations of the extract (0.05% to 10%) were analyzed. Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) were also assessed to identify the lowest effective concentrations. The ethanol extract demonstrated significant antibacterial activity; notably, the largest inhibition zone measured 30.74 mm at a concentration of 10%. Effective MICs were as low as 0.1% for all tested bacteria, while MBCs ranged from 0.1% to 0.4%. These results suggest that ethanol extracts of Kersen flowers exhibit potent antibacterial properties against major gastrointestinal pathogens, supporting further exploration of these extracts as a natural antibacterial treatment and offering a potential alternative to conventional antibiotics.
Antibacterial Activity of Ethanol Extract of Cocoa Leaves (Theobroma cacao L.) Against Gastrointestinal Infection Bacteria Tract Infection by Agar Diffusion Method Sya’baniyah Herman, Nur Fajriah; Fitriana, Fitriana; Maryam, St.
Journal Microbiology Science Vol 5, No 1 (2025)
Publisher : Fakultas Farmasi, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jms.v5i1.1218

Abstract

The cocoa plant (Theobroma cacao L.) leaves contain secondary metabolites, including flavonoids, saponins, and tannins, known for their potential antibacterial properties. This study aims to evaluate the antibacterial activity of the ethanol extract of cocoa leaves (Theobroma cacao L.) against bacteria that cause gastrointestinal infections using the agar diffusion method. The study assessed the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of the extract. The results showed that the ethanol extract exhibited significant antibacterial activity, particularly at concentrations of 2.5%, 5%, and 10%, with the highest inhibition zone observed at 10% concentration. The extract was most effective against Escherichia coli, Salmonella typhi, Shigella dysenteriae, and Vibrio cholerae, with inhibition zones of 15.34 mm, 15.60 mm, 13.81 mm, and 16.43 mm, respectively. These findings suggest that cocoa leaf extract has the potential to be developed as an antibacterial agent against gastrointestinal pathogens.
Co-Authors A. Muflihunna, A. Agustiani, Eka Agustin, Verren Regina Akung Daeng Alodya, Baiq Putri amelia yolanda, amelia Aminah Aminah Annisa, Nurfiqah arifin, nurrizky afiah Arini, Gusti Ayu Asri, Fitriani Asriani Suhaenah Azzahra, Resqinah B, Moh Baktiar Desi, Nilma Sri EMI SALMAH Fajar, Suwandy Fitriana Fitriana Fuady, Helmi Hidayanti, Nurul Hidayat, M. Ali Akbar Indriyani , Maulida Irwan Irwan Irwan, M Irwan Iwan Harsono Khoirul Umam Lambang Basri Said M. Firmansyah M. Irwan M. Irwan, M. Irwan Masdiana Tahir Mayanah, Dewi Muhammad Awaludin Muhammad Firmansyah, Muhammad Mustika, Nurfadila Muzakkir Baits, Muzakkir Nur Awwalunnisa, Nur Ohorela, Indah Kartika p, irmawan jamal Parobi, Rizki Prima Astuti Handayani Putra, Iwan RAHMAN, ANDI AMALIA RAMADHANI Rahmawati, Rahmawati Rais Razak, Rais Ramdani, Ridho Rekhan. T, Muh Rafli Rusniyanti, Rusniyanti Rustam, Julis Tina Sahri Sahri Salahuddin, Muthia Amaliah Salim, Medina Sasliani, Sasliani Satarudin Siti Helmyati Syam, Nurizzah Aulia Sya’baniyah Herman, Nur Fajriah Wahidin Wahidin Wahyudi, M. Ilham Wiwik Handayani