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All Journal Majalah Kedokteran Sari Pediatri Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Cermin Dunia Kedokteran
Sudung O Pardede, Sudung O
Departemen Ilmu Kesehatan Anak FKUI RS Dr. Cipto Mangunkusumo, Jakarta
Biochemistry, Genetics & Molecular Biology Education Health Professions Medicine & Pharmacology Public Health

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Faktor Risiko Epilepsi Intraktabel pada Anak dengan Epilepsi Umum Mangunatmadja, Irawan; Mulyani, Dina Indah; Pardede, Sudung O; Tridjadja, Bambang; Wulandari, Harjanti F
Majalah Kedokteran Indonesia Vol 69 No 2 (2019): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.69.2-2019-72

Abstract

Introduction: Several datas studied of intractable epilepsy risk factors areavailable in childhood epilepsy. The objectve of this reasearch to investigatethe role of early or evolution several factors on childhood with generalizedepilepsy as risk factors of intractable epilepsy. Methods: Retrospective cohort study was conducted at neurology out patient pediatric and private outpatient clinic Cipto Mangunkusumo Hospital between January 2010 to December 2013. The inclusion criteria was childhood gener-alized epilepsy with age 1 month up to 18 years old which has been treated with anti epileptic drugs for at least 6 months. Risk factors were analyzed with bivariate and multivariate analysis. Results: Prevalence of intractable generalized epilepsy is 21% of 102 subject. Bivariate analysis showed that age onset of seizure, initial seizure frequency, non-responder of early treatment, unfavorable gross motor development evo-lution and unfavorable epilepti form EEG evolution were significantly associated with intractable epilepsy. Based on multivariate analysis only non-responder of early treatment (p less than 0.001) and age onset less than 1 year old (p less than 0.001). Conclusions. Non-responder early treatment and age onset of seizure less than 1year old are strongly associated with intractable in childhood generalized epilepsy.
Co-Authors Alvina Christine Annisa R.Yulman Antonius Pudjiadi Ari Prayitno Ariani Dewi Widodo Arwin AP Akib Bambang Supriyatno Bambang Tridjadja, Bambang Bambang Tridjaja AAP, Bambang Tridjaja Bernadetha Nadeak Bernadetta Nadeak Bonny Tjongjono Cahyani Gita Ambarsari Cindy D. Christie Darmawan B. Setyanto Dewi K. Suryani Dewi Kartika Suryani Diana Adriani Banunaek Dina Indah Mulyani, Dina Indah Dina Muktiarti, Dina Edwin Kinesya Eka L. Hidayati Eka Laksmi Hidayati, Eka Laksmi Elizabeth S. Susanti Elsye Souvriyanti Evita B. Ifran Hardiono Pusponegoro Hartono Gunardi Hendri Tanu Jaya, Hendri Tanu Henny Adriani Puspitasari Henny Adriani Puspitasari Ihat Sugianti Irawan Mangunatmadja Jose RL Batubara Jumaini Andriana Jumaini Andriana Ludi D. Rahmartani Mulya R Karyanti Mulya Rahma Karyanti, Mulya Rahma Mulyadi M. Djer Niken Wahyu Puspaningtyas Nitish Basant Adnani Partini P. Trihono Partini P. Trihono Partini P. Trihono Partini Pudjiastuti Trihono Putri Maharani Ratih Puspita Ratih Puspita Reza Fahlevi Rhyno Febriyanto Rini Sekartini Rismala Dewi Rosalina D Roeslani Selli Muljanto Swanty Chunnaedy Swanty Chunnaedy Taralan Tambunan Taralan Tambunan Taralan Tambunan Tjhin Wiguna Wardhana, Aditya William J. Iskandar Wulandari, Harjanti F Wulandari, Harjanti F Yoga Devaera Zakiudin Munasir