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All Journal Jurnal Gizi NUTRIRE DIAITA Indonesian Journal of Human Nutrition Amerta Nutrition Pontianak Nutrition Journal (PNJ) Jurnal Gizi Kerja dan Produktivitas Caring : Jurnal Pengabdian Masyarakat ASMAT: Jurnal Pengabmas Pontianak Nutrition Journal (PNJ) Prosiding Seminar Nasional Unimus
Eva Putri Arfiani
Department Of Nutrition, Faculty Of Health Sciences, Universitas Brawijaya
Agriculture, Biological Sciences & Forestry Humanities Dentistry Education Engineering Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Other

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Journal : NUTRIRE DIAITA

 1 
PENGARUH PEMBERIAN TEPUNG BUAH KESEMEK (Diospyros kaki var. Junggo) SECARA ORAL TERHADAP PEMBENTUKAN FOAM CELLS DI LAPISAN INTIMA AORTA TIKUS PUTIH (Rattus novergicus strain wistar) YANG DIBERI DIET ATEROGENIK Arfiani, Eva Putri; Julia, Arliek Rio; Kusumastuty, Inggita
Jurnal Nutrire Diaita (Ilmu Gizi) Vol 9, No 01 (2017): NUTRIRE DIAITA
Publisher : Lembaga Penerbitan Unversitas Esa Unggul

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47007/nut.v9i01.1721

Abstract

Coronary Heart Disease (CVD) is the manifestation of atherosclerosis which is formed of foam cells formation. Beside of medicine, the alternative way to prevent CVD is by high soluble fiber food consumption such as persimmon fruit (Diospyros kaki var. Junggo). The aim of this experiment was to understand the effect of persimmon fruit toward the foam cells formation in the intima aorta layer of rat (Rattus novergicus strain wistar) with atherogenic diet. The experiment was conducted by using experimental laboratoric in vivo with True Experimental Design (Post Test-Only Control Group Design) about 12 weeks, using 5 male rats/group + 1 male rat for spare in each group, the age about 56120 days, and the weight about 100-200 g. The experimental rats were divided into 5 groups, i.e P0 (30.6 g normal diet), P1 (22.9 g atherogenic diet), P2 (22.4 g atherogenic diet + 1.2 g persimmon flour), P3 (21,9 g atherogenic diet + 2.4 g persimmon flour), and P4 (21.4 g atherogenic diet + 3,6 g persimmon flour). Calculation of foam cells was carried out using light microscop with 400x magnification in the area of intima aorta layer of rat. The experiment proved that persimmon flour intervention orally could reduce foam cells formation in the intima aorta layer of white rat with atherogenic diet.  Keywords: atherogenic diet, persimmon, soluble fiber, foam cells
Co-Authors Adelya Desi Kurniawati Afifah Yasyfa Dhiyanti Anisa Handayani Anita Puspa Widiyana Arliek Rio Julia, Arliek Rio Bachtiar Rifai Pratita Ihsan Diah Royani Meisani Dina Elok Wulandari Dina Elok Wulandari Dini, Cleonara Yanuar Eka Widyanti, Laras Ristati Iin Diah Karina Inggita Kusumastuty Iva Tsalissavrina Jaya Mahar Maligan Laksmi Karunia Tanuwijaya Laksmi Karunia Tanuwijaya Lola Ayu Istifiani Luthfi Ahmad Muchlashi Luthfiya, Rania Ishma Neneng Fina Mafazah Purnama, Sarah Desty Sembiring, Lydia Gresari Sulistya, Rakhma Indah Susetyowati Tiara Dian Novitasari Tiara Dian Novitasari Titis Sari Kusuma VALENTINA YURINA Yati Soenarto Yosfi Rahmi Yudi Arimba Wani Yudi Arimba Wani Yudi Arimba Wani, Yudi Arimba