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All Journal VALENSI Pharmaciana: Jurnal Kefarmasian Jurnal Penelitian Pendidikan IPA (JPPIPA) Celebes Abdimas: Jurnal Pengabdian Kepada Masyarakat Jurnal farmasi UIN Alauddin Makassar Borneo Journal Of Pharmascientech Jurnal Pengabdian kepada Masyarakat Nusantara Jurnal Mandala Pengabdian Masyarakat Jurnal Pengabdian Masyarakat Indonesia Jurnal DiMas (Jurnal Pengabdian Kepada Masyarakat) Jurnal Farmasi Sains dan Praktis Duta Abdimas: Jurnal Pengabdian Masyarakat Journal of Pharmaceutical and Sciences. Acta Holistica Pharmaciana Jurnal Medika: Medika Jurnal Insan Pengabdian Indonesia Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Viani Anggi
College Of Pharmaceutical Sciences Pelita Mas Of Central Of Sulawesi,
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Penyuluhan Stunting : Upaya Meminimalisir Tingginya Angka Stunting di Desa Sawidago: Penyuluhan Stunting : Upaya Meminimalisir Tingginya Angka Stunting di Desa Sawidago Puspita Dewi, Niluh; mariyani, mariyani; Alaydrus, Syafika; Anggi, Viani; Magfirah, Magfirah; Kurnia Utami, Indah
Jurnal Dimas Vol 5 No 2 (2023): Jurnal Pengabdian Kepada Masyarakat
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/dimas.v5i2.69

Abstract

Indonesia has quite a serious nutritional problem which is characterized by many cases of malnutrition. Malnutrition is an impact of nutritional status. Stunting is a condition of malnutrition that is related to past nutritional deficiencies, so it is a chronic nutritional problem. Many factors can cause stunting in toddlers, such as toddler characteristics and socio-economic factors. Community outreach activities are carried out with the aim of providing education to the public regarding the risk factors for stunting and its prevention. This counseling was carried out in order to increase the knowledge of the residents of Sawidago Village, especially mothers, because the mother is the person who is always with the child from pregnancy to 24 months of age. So that the baby's development will continue to be assisted by the mother. Counseling is provided using an interactive lecture method through posters and distribution of leaflets as well as social service. The effectiveness of the extension was tested by administering a partner satisfaction questionnaire with the activities carried out. The results of activity observations showed that Partners were satisfied with the outreach activities carried out.
Effectiveness Test of Mangrove Leaf (Rhizophora Apiculata) on Decreasing Blood Glucose Levels and Pancreas Histopatology Streptozotocin Induced Male White Rats Tandi, Joni; Fahri, Mohammad; Fatma, Nurul; Anggi, Viani; Patala, Recky; Handayani, Tien Wahyu
Jurnal Penelitian Pendidikan IPA Vol 9 No 6 (2023): June
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i6.3789

Abstract

Hyperglycemia, a symptom of diabetes mellitus, can lead to oxidative stress, which is indicated by elevated malondialdehyde levels. Mangrove (Rhizophora apiculata) contains secondary metabolites of alkaloids, flavonoids, saponins and tanins, this can lessen how much oxidative stress there is in DM. This study intends to demonstrate the efficacy of mangrove extracts in lowering blood glucose levels and detecting pancreatic damage. The study used 30 male Wistar rats which were divided into 6 groups (group I: normal control, group II: negative and group III: positive control given glibenclamide 0.45 mg) and the test group (trial group). group IV: level 25 mg/kg BW, group V: level 50 mg/kg BW and VI: level 75 mg/kg BW) The DM model was made by streptozotocin induction. Pancreatic damage seen at 700 magnification saw pancreatic β cells as well as the islets of Langerhans' endocrine cells. The results of research on ethanol from mangrove leaves at levels of 75 mg/kg BW are substances that are effective at lowering blood sugar levels, which on average were 105 mg/dL with a hazard value of 1.2. When compared with glibenclamide mangrove extract is not equivalent to glibenclamide but has lowered glucose levels.
Anticancer Activity of Rosella Flowers (Hibiscus Sabdariffa l.) In HepG2 cells Anggi, Viani; Patala, Recky; Arfiah, Arfiah; Dewi, Niluh Puspita
Jurnal Penelitian Pendidikan IPA Vol 9 No SpecialIssue (2023): UNRAM journals and research based on science education, science applic
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9iSpecialIssue.6350

Abstract

The natural ingredients of rosella flowers have the potential as natural anti-cancer and chemopreventive agents, contain secondary metabolite compounds with cancer therapeutic mechanisms with inhibiting and killing cancer cells and their development through inhibition of apoptosis (cell death program) and in vitro inhibited cell flow. The study aims to identification of secondary metabolite compounds and also determine the cytotoxic activity of ethanol extract from the rosemary plant against HepG2 cancer cells. This study used by identification of secondary metabolite compounds of ethanol extract from the rosemary plant (Hibiscus sabdariffa L.) and the cytotoxicity test used with MTT assay on HepG2 liver cancer cells with a test concentration series of 12,5; 25; 50; 100; 200; 250; 500 and 1000 µg/ml. : The results showed the secondary metabolite compounds of rosella flowers have flavonoids, alkaloids, saponins and tannins and data of 50% cell growth inhibition activity, which was showed that rosella flower had IC50 values 629,919 μg/mL. The ethanol extract of rosella flowers have activity on HepG2 cells growth inhibition had considered moderately active anticancer activity
Safety Profile of Abelmoschus Manihot (L.) Medik Ethanol Leaf Extract: Acute Toxicity Study in Animal Models Pantua, Magfira B.; Anggi, Viani; Utami, Indah Kurnia; Rakanita, Yasinta
Jurnal Penelitian Pendidikan IPA Vol 10 No 9 (2024): September
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i9.9172

Abstract

Abelmoschus Manihot (L.) Medik, commonly known as Abelmoschus manihot, is a traditional medicinal plant from Palu, Central Sulawesi, Indonesia, widely utilized for its potential health benefits. This research aims to evaluate the acute toxicity of ethanol extract from Abelmoschus manihot leaves, focusing on determining the lethal dose (LD50) in rats. The study involved extracts being administered at a range of doses of 500 mg/kg, 1000 mg/ kg, and 2000 mg/Kg of body weight (BB) in a rat population. Rats were observed for 24 hours to look for signs of toxicity and death. The LD50 value, which determines the dose required to cause death in 50% of the test population, is calculated based on the results. This research provides insights into the safety profile of ethanol extract from Abelmoschus manihot leaves and contributes to understanding its potential risks when used in traditional medicine. No significant deaths were observed at lower doses, but higher doses resulted in observable toxic effects, indicating the need for careful dosing in therapeutic applications. The results show that although Abelmoschus Manihot did not exhibit acute toxic effects on rats at doses of 500 mg/kg, 1000 mg/kg, and 2000 mg/kg body weight. No significant deaths or severe toxic symptoms were observed during the 24-hour observation period up to the 14-day observation, and there were no differences in the body weight of the rats during the 14-day observation
Co-Authors Aisyah Marzuki, Sitti Alaydrus, Syafika Anastasya P, Michele Arfiah, Arfiah Astria, Nani Dewi Sufiani Fahri, Mohammad Fatma, Nurul Handayani, Tien Wahyu Islamiati, Utami Isna Paula Joni Tandi Joni Tandi, Joni Kurnia Utami, Indah L, Wahyudin H LUKMAN, LUKMAN M, Yulan Magfirah, Magfirah Magfiroh Magfiroh Mariyani, Mariyani Muh. Afif Wahyudi Eyato Nadila Nadila Nadila, Nadila Nani Astria Niluh Puspita Dewi Niluh Puspita Dewi Niluh Puspita Dewi, Niluh Puspita Novina, Patricia Nur Ikhwan Nur Sakina Nurul Insani, Nabila Pantua, Magfira B. Puspita Dewi, Niluh Rafni, Rafni Rahmawati D Rakanita, Yasinta Recky Patala Sara, Priskila El Sufiani, Dewi Syafika Alaydrus Tien Wahyu Handayani Tudaan, Leligrafela Utami, Indah Kurnia Veronika Veronika Veronika Veronika Vidya Christin Wahyu Handayani, Tien Yasinta Rakanita Yenni Putri Lestari