Arief S. Kartasasmita
Department Of Ophthalmology, Faculty Of Medicine, Padjadjaran University Cicendo National Eye Center, Bandung, West Java

Published : 32 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 32 Documents
Search

Ocular Manifestations of Aplastic Anemia: Rare Case of Anemic Retinopathy Juanarta, Pieter; Ihsan, Grimaldi; Iskandar, Erwin; Kartasasmita, Arief; Virgana, Rova; Indra, Made
International Journal of Retina Vol 8 No 1 (2025): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2025.vol008.iss001.280

Abstract

Incidence of aplastic anemia was 1-2 cases per million population per years, and showed higher rate in Asia and 10-25 years old. Anemic retinopathy can occur in 28% of patient with severe anemia, especially if accompanied by thrombocytopenia. Most cases were asymptomatic, however decrease visual acuity were also commonly found caused by haemorrhage and Macular edema. A 65 years old female patient came with blurry vision ten days prior admission accompanied with loss of consciousness, recurrent bleeding from nose, gum, and bluish discoloration in her extremities four years ago. Visual acuity was 1/60 on the right eye and 0.4 log on the left eye. Funduscopic examination showed vitreous haemorrhage, dot blot, hard exudate, and tortuosity of vein. Laboratory Examination showed anemia and thrombocytopenia, and peripheral blood morphology showed normochromic anisopoikilocytosis caused by chronic disease. She was scheduled to underwent anti VEGF and showed improvement in her visual acuity after injection. Fundoscopic examination later shows sub-hyaloid haemorrhage, dot blot, hard exudate, and tortuosity of vein. She was scheduled to undergo pars plana vitrectomy and were consulted to internal medicine. Aplastic anemia is a rare disease that usually asymptomatic, thus causing late intervention and a high mortality rate. Early manifestation can be seen in retinal structure as anemic retinopathy thus ophthalmologist have valuable impact in early detection of this disease. Haemorrhage overlying the macula and macular edema is the most common cause of visual impairment. Anti VEGF treatment, transfusion of blood component, and immunosuppressive therapy is needed to prevent complication and increase patient survival rate. Patient visual acuity usually imporved after early transfusion and anti VEGF injection, however delayed intervention may cause irreversible vision loss.
A Rare Case Of Retinal Arterial Microaneurysm: Clinical Features And Diagnostic Insights Yuna, Uray Nabila; Ihsan, Grimaldi; Virgana, Rova; Kartasasmita, Arief S.; Iskandar, Erwin; Widyanatha, Made Indra
Indonesian Journal of Medicine Vol. 10 No. 1 (2025)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2025.10.1.773

Abstract

Background: In Retinal Arterial Macroaneurysms (RAM), the central retinal artery suffers from acquired focal hypertension. Clinical manifestations of the disease are diverse and easily misdiagnosed. Several imaging modalities may be used in order to confirm the diagnosis of RAM. This article aims to describe the clinical features and method of diagnosis of an uncommon case of retinal artery microaneurysm. Case report: A 57-year-old woman presented with a progressive loss of vision in her right eye months prior. Visual acuity in the right eye was 0.8 log 13. Upon funduscopic inspection of the right eye, firm exudates with low tortuosity and submacular hemorrhage were observed. The right eye’s OCTA revealed a localized expansion and significant constriction with twisted blood vessels on the reverse side of the deformed vessel, while the OCT of the macula revealed submacular hemorrhage. The patient was diagnosed with ruptured retinal Arterial Macroaneurysm or Macular Telangiectasia Type I and Retinopathy Hypertensive Grade II of both eyes, No Diabetic Retinopathy of both eyes with Diabetes Mellitus and Hypertension. The right eye of the patient received concentrated laser photocoagulation and an intravitreal injection of anti-VEGF. Conclusion: RAM is an acquired vascular disease defined by restricted, fusiform, or saccular dilation in the first three arteries of the main retinal artery. Retinal microaneurysms can be diagnosed with various imaging modalities. Ram may be treated with intravitreal anti-VEGF drugs, combination therapy, or laser photocoagulation.