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All Journal HAYATI Journal of Biosciences Hemera Zoa Jurnal Sains Materi Indonesia Indonesian Journal of Pharmaceutical Science and Technology Indonesian Journal of Biotechnology Jurnal Sumberdaya Hayati Jurnal Pembelajaran dan Biologi Nukleus Molekul: Jurnal Ilmiah Kimia
Berry Juliandi
Department Of Biology, Faculty Of Mathematics And Natural Science, IPB University, Bogor 16680, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Earth & Planetary Sciences Education Environmental Science Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology

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Preparation and characterization of nanopowder of Acalypha hispida Leaves Extract Using Planetary Ball Milling Hamzah Alfarisi; Siti Sa'diah; Berry Juliandi; Tutik Wresdiyati
Molekul Vol 17 No 1 (2022)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jm.2022.17.1.5601

Abstract

Acalypha hispida Burm.f. is commonly used as an ornamental plant known for pharmacological effects. The nanoscale extract increases bioavailability and bioactivity. This research aimed to produce and characterize nanopowder extract of A. hispida leaves. Powdered leaves were macerated in 96% ethanol, then was evaporated in the spry dryer. Nanopowder extract was produced using planetary ball milling at 5000 rpm in different milling times, namely 5 minutes (nanopowder A), 10 minutes (nanopowder B), and 40 minutes (nanopowder C). The nanopowder extracts were evaluated using a particle size analyzer, scanning electron microscope, and high-performance liquid chromatography. The average particle size of A. hispida crude extract was 1271 nm, and nanopowder A, B, and C respectively were 837.1 nm, 803.8, and 512.2 nm. The polydispersity index of A. hispida crude extract, nanopowder A, B, and C were 0.754, 0.696, 0.717, dan 0.612. The milling process for 40 minutes reduced the content of 5% gallic acid and 10.3% catechin. The SEM image of nanopowder C was smaller than crude extract. The best average particle size of nanopowder C (512.2 nm) and polydispersity index (0.612) were produced using PBM for 40 minutes at 5000 rpm.
Effects of Surfactants on Biological, Physiological, and Histological Performance of Mahseer Seeds, Neolissochilus soro Rizkiya, Iffi; Juliandi, Berry; Nirmala, Kukuh; Puspaningsih, Dewi; Taufik, Imam
HAYATI Journal of Biosciences Vol. 31 No. 2 (2024): March 2024
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.4308/hjb.31.2.367-373

Abstract

Mahseer (Neolissochilus soro) grows and develops in Indonesian lakes and rivers. However, in line with the increase in population, the pollution load that enters water bodies is increasing due to anthropogenic activities along the river. One of the chemicals that can potentially be a source of water pollution is Linear Alkylbenzene Sulfonate (LAS). This study aims to determine the lethal toxicity of LAS surfactant to mahseer and to analyze the sub-lethal effect of this surfactant on the biological, physiological, and histological conditions of mahseer seeds. Parameters studied included lethal toxicity (LC50), sub-lethal toxicity, and biological, histological, and hematological conditions. The results showed that the LAS surfactant had an LC50-96 hour value of 6.14 mg/L in mahseer and was classified as highly toxic. Fish exposed to LAS for 40 days experienced a decrease in specific growth rate and feed efficiency as the surfactant concentration increased. Exposure to LAS also decreases the number of erythrocytes, hemoglobin, hematocrit, and blood sugar levels while increasing the number of leukocytes. There was also damage to the gills of fish exposed to LAS. In general, the sub-lethal concentration of LAS negatively affected mahseer seeds.
Kompleksitas Obyek dan Running-Wheel Mempengaruhi Novel Object Recognition Test pada Mencit (Mus musculus) HANIM, NISFA; WIDYASTUTI, SALMAH; ALFIYAN, ACHMAD; AKBAR, MUHAMMAD AZHARI; JULIANDI, BERRY
Jurnal Sumberdaya Hayati Vol. 4 No. 1 (2018)
Publisher : Departemen Biologi, Institut Pertanian Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jsdh.4.1.7-11

Abstract

This research aimed to confirm the tendency of mice to novel object, effect of exercise (in running-wheel) toward memory of mice and to test tendency of mice in avoiding predator signal in novel object. Novel object recognition test (NORT) used to test the memory the day after acquisition phase (NORT I) and memory one week after exercise was given (running-wheel) (NORT II). The result showed that there was no tendency of mice in exploring toward novel object in both NORT I and NORT II. This might happen because the complexity of familiar object higher than novel object, so the familiar object could accommodate more activities. Exercise using running-wheel in mice had an effect on memory, it could be seen in decreasing duration of object exploration time from NORT I to NORT II. There was no tendency in avoiding predator’s signal on novel object which was attached by urine addition (odor signal).
Perilaku Mencit (Mus musculus) terhadap Feses Ular Kobra Jawa (Naja sputatrix): The Behavior of Mice (Mus musculus) towards Feces Stimulant from Javanese Spitting Cobra (Naja sputatrix) Kartika Marta Djakaria; Nurhardiyanti Munawaroh, Anggi; Mardilah; Quraisy Zakky; Ruhama Maya Sari; Berry Juliandi
Jurnal Sumberdaya Hayati Vol. 6 No. 1 (2020)
Publisher : Departemen Biologi, Institut Pertanian Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jsdh.6.1.13-19

Abstract

This research aimed to confirm the predator avoidance behavior of mice from snake droppings as a stimulant. Snake droppings are obtained from snakes fed with mice that come from the same strain as the mice being tested for response. Snake droppings were diluted into three different concentrations (25%, 50%, and 75%). The results showed that male individuals tend to avoid the odor stimuli than the female, it’s shown by the higher avoidance duration in males than the females. The results also indicate that innate behavior takes role in the avoidance response since the mice have never been exposed to any presence of predator.
Antennal Sensilla of Queen and Worker Giant Honey Bee Apis dorsata and Stingless Bee Trigona laeviceps in Difference of Density and Ultramorphometric Analysis Hutabarat, Desmina Kristiani; Raffiudin, Rika; Juliandi, Berry
JURNAL PEMBELAJARAN DAN BIOLOGI NUKLEUS Vol 10, No 3: Jurnal Pembelajaran Dan Biologi Nukleus November 2024
Publisher : Universitas Labuhanbatu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36987/jpbn.v10i3.5502

Abstract

Antennal sensilla receive many stimuli from the environment. Thus, it is crucial to study the structure of antennal sensilla, especially in the eusocial bees, such as the honey bee Apis dorsata and stingless bee Trigona laeviceps; both have females, queens and workers with different tasks in their colonies. We aimed this study to describe the types, density, distribution, and ultramorphometric measurements of antennal sensilla of queens and workers of A. dorsata and T. laeviceps. The antennae of ten workers and one queen of A. dorsata and T. laeviceps were analyses using scanning electron microscopy. This study revealed two new sensilla types, chaetica and ceoloconica of  A. dorsata workers. We also describe seven new types of sensilla of T. laeviceps workers and queen: trichodea, placodea, basiconica, campaniformia, ampullacea, chaetica, and coeloconica. The current study found caste differentiation in the densities of antennal sensilla: the density of antennal sensilla in the workers is higher compared to the queen, both in A. dorsata and T. laeviceps. Age polyethism in the worker caste presumably shapes the diversity of sensilla. Further, asymmetry distribution was observed in the anterior and posterior sides of the antenna, with the anterior sensilla having nearly twice the density of sensilla compared to the posterior side, in both species of worker caste. In ultramorphometric studies we found that trichodea in A. dorsata workers is larger than that of  T. laeviceps workers, while interestingly, the placodea of the giant honey bee A. dorsata is smaller than that of the smaller T. laeviceps.
Effect of Phosphate-based Glass Porous Microspheres (P30) Loaded with Extracellular Vesicle on Osteoblast Behaviour: In Vitro Study Cahayadi, Sigit Daru; Nuzulia, Nur Aisyah; Boediono, Arief; Ahmed, Ifty; Nurhayati, Retno Wahyu; Sari, Yessie Widya; Juliandi, Berry
HAYATI Journal of Biosciences Vol. 32 No. 4 (2025): July 2025
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.4308/hjb.32.4.840-849

Abstract

Bioactive materials, particularly phosphate-based glasses (PBG), hold great promise in bone repair due to their controllable degradation rates and bioactivity. This study evaluated PBG porous microspheres (P30) loaded with extracellular vesicles (EVs) for bone tissue engineering, focusing on osteogenesis, EV uptake, and cell invasion. P30 concentrations (5P30, 10P30, 50P30, 100P30, 500P30) were tested for their effects on calcification, EV uptake, and cell migration. Results showed that 100P30 exhibited optimal conditions for osteogenesis and EV delivery, with the highest calcification areas at both Day 7 and Day 14 and the most efficient EV internalization. Meanwhile, 500P30 demonstrated the highest cell migration, supporting pre-osteoblastic migration at this concentration. These findings indicate that 100P30 is ideal for mineralization and EV uptake, while 500P30 enhances cell invasion. This study highlights P30's versatility as a biomaterial for bone regeneration, with specific concentrations tailored to different regenerative goals. These results underscore the potential of P30 microspheres loaded with EVs as an effective strategy for promoting bone repair and regeneration.
Comparative Analysis of Bioactive Compounds in Invasive and Native Land Snail Species of Java, Indonesia Pertiwi, Meilisha Putri; Nurinsiyah, Ayu Savitri; Juliandi, Berry; Priawandiputra, Windra; Iskandar, Johan
HAYATI Journal of Biosciences Vol. 32 No. 5 (2025): September 2025
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.4308/hjb.32.5.1324-1336

Abstract

Land snails are part of Indonesia's rich biodiversity. Their mucus is widely used as a natural ingredient in pharmaceuticals and cosmetics. Despite this, research has primarily focused on a limited range of species, leaving the potential of many native land snail species unexplored. This indicates that there is still significant untapped potential in native Indonesian land snail species. This research aims to analyze the bioactive compounds in the mucus of native Indonesian land snails and compare them with those of invasive species. The research employed Liquid Chromatography-Mass Spectrometry (LC-MS) to identify biologically active substances in land snail mucus. The samples used were Amphidromus palaceus and Lissachatina fulica collected from Gunungkelir, Yogyakarta, and Amphidromus perversus from Gunungkidul, Yogyakarta, and Jember, East Java. The results revealed that A. palaceus exhibited the highest number of bioactive compounds, with 28 identified substances. The bioactive properties across all samples were categorized as antibacterial (16%), wound healing and anti-inflammatory (12%), anticancer (8%), neuron-related drugs (6%), anti-aging (4%), with the remaining activities related to liver-related drugs, antiviral, heart disease-related drugs, and kidney disease-related drugs. These results highlight that native species have significant potential for further research, enabling their application in medicine and cosmetics.
Co-Authors Ahmad Sulaiman Alwahdy Ahmed, Ifty AKBAR, MUHAMMAD AZHARI ALFIYAN, ACHMAD Aloma Karo Karo Alwahdy, Ahmad S. Anggi Nurhardiyanti Munawaroh Araz Meilin Arief Boediono Boenjamin Setiawan Budiariati, Vista Cahayadi, Sigit Daru Dian Anggraini Dwi Budiono Fahri Fahri Grace Tj. Sulungbudi Hamzah Alfarisi Hamzah Alfarisi HANIM, NISFA Harry Murti Hutabarat, Desmina Kristiani Imam Taufik Indra Bachtiar Innayah Zahara Irham Abdul Azis Jasmi Jasmi Jauharlina Jauharlina Johan Iskandar Kartika Marta Djakaria Kelvin Yaprianto Kinichi Nakashima Kukuh Nirmala Kurniawan, Mohammad Lamerkabel, J. S. A. Mahardika Gama Pradana Mardilah Meilisha Putri Pertiwi Mokhamad Fahrudin Mujamilah Mujamilah Nisfia Rakhmatun Nisa Nunung Yuniarti Nurhayati, Retno Wahyu Nurinsiyah, Ayu Savitri Nuzulia, Nur Aisyah Puji Lestari Puspaningsih, Dewi Puspita E. Wuyung Puspita Eka Wuyung Qashiratuttarafi Qashiratuttarafi Quraisy Zakky Ramli, Yetty Ratih Rinendyaputri Ratih Rinendyaputri Ratih Rinendyaputri RIKA RAFFIUDIN Rizkiya, Iffi Ruhama Maya Sari Siti Sa'diah Siti Sa'diah Subangkit, Mawar Susanto, Yayi D.B. Tri Atmowidi Tsukasa Sanosaka Tutik Wresdiyati WIDYASTUTI, SALMAH Wildan Mubarok Wildan Z.L. WINDRA PRIAWANDIPUTRA, WINDRA Yayi Dwina Bilianti Susanto Yessie Widya Sari Yulia Pujiastuti