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All Journal Jurnal Riset Kesehatan Jurnal Analis Kesehatan Klinikal Sains (Jurnal Analis Kesehatan) Jurnal Kesehatan Al-Irsyad Jurnal Mitra Kesehatan JURNAL INOVASI DAN PENGABDIAN MASYARAKAT INDONESIA Journal of Innovation Research and Knowledge Pharmaqueous Jurnal Kesehatan Jurnal Kesehatan Bakti Tunas Husada Jurnal Ilmiah Nusantara JES-TM Social and Community Service
Meka Faizal Farabi
Universitas Al-Irsyad Cilacap
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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CORRELATION OF HBA1C LEVELS TO LDL, HDL AND TRIGLYCERIDE LEVELS IN TYPE 2 DIABETES MELLITUS PATIENTS IN KESUGIHAN II PUBLIC HEALTH CENTER, CILACAP DISTRICT Lestari, Tika; Puspodewi, Dini; Farabi, Meka Faizal
Jurnal Mitra Kesehatan Vol. 8 No. 1 (2025): Jurnal Mitra Kesehatan
Publisher : STIKes Mitra Keluarga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47522/jmk.v8i1.421

Abstract

Introduction: Diabetes mellitus or DM is a disease characterized by hyperglycemia due to abnormalities in insulin secretion, insulin action, or both. To avoid complications, patients with type 2 DM with uncontrolled blood glucose levels require comprehensive treatment. Poor glycemic control results in changes in lipid profiles in type 2 DM patients. The purpose of this study was to prove the correlation of HbA1c levels with LDL, HDL, and Triglyceride levels in Type 2 DM patients at the Kesugihan II Cilacap Health Center. Methods: This study design was cross-sectional. Examination of HbA1c, LDL, HDL, and Triglyceride without comorbidities of Heart, Hypertension, and Stroke. The sample was Prolanis Type 2 DM patients who met the inclusion and exclusion criteria. The analysis used for the normality test was the Shapiro-Wilk test and the nonparametric test used the Spearman test. Results: The Spearman test results between HbA1c levels and LDL levels showed a p value = 0.216, between HbA1c levels and HDL levels showed a p value = 0.123, between HbA1c levels and triglyceride levels showed a p value = 0.326. This shows that the probability is more than 0.05. The conclusion of this study is that there is no correlation between HbA1c levels with LDL, HDL and triglyceride levels in Prolanis DM Type 2 patients at the Kesugihan II Cilacap Health Center.
Analisis Profil Protein dan Total Protein Tempe Mendoan Asal Cilacap Dengan Berbagai Durasi Fermentasi Menggunakan SDS-PAGE Putri, Reza Amelia; Farabi, Meka Faizal; Nugroho, Yusuf Eko
Jurnal Analis Kesehatan Vol. 14 No. 2 (2025): JURNAL ANALIS KESEHATAN
Publisher : Department of Health Analyst, Politeknik Kesehatan, Kementerian Kesehatan Tanjungkarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jak.v14i2.5169

Abstract

Di Indonesia tanaman kedelai (Glycine max (L) Merill) banyak dibudidayakan, tetapi bukan tanaman asli Indonesia. Salah satu produk olahan kedelai yang gemar dikonsumsi oleh masyarakat adalah tempe, merupakan makanan tradisional dari Indonesia. Penelitian ini bertujuan untuk mengetahui total protein dan profil protein tempe mendoan dengan durasi fermentasi 24, 48, dan 72 jam, guna mengetahui waktu fermentasi terbaik dalam menghasilkan kandungan protein yang tinggi. Analisis profil protein dan total protein dilakukan secara deskriptif yang ditabulasi dalam bentuk tabel dan dihitung rata-rata menggunakan JASP serta Microsoft Excel untuk mengetahui nilai absorbansi kurva baku. Hasil penelitian menunjukkan bahwa total protein tertinggi pada fermentasi 48 jam sebesar 2,65 μg/μL, diikuti oleh fermentasi 72 jam (2,32 μg/μL) dan terendah pada fermentasi 24 jam (1,48 μg/μL). Hasil SDS-PAGE menunjukkan bahwa semua sampel memiliki pita protein minor dengan berat molekul 74 kDa, 70 kDa, 48 kDa, 40 kDa, 31 kDa, 26 kDa, dan 10 kDa. Pada fermentasi 48 jam terdapat pita protein mayor 40 kDa, mengindikasikan bahwa pita yang lebih tebal (Mayor) memiliki konsentrasi protein yang lebih tinggi. Hasil penelitian menunjukkan bahwa fermentasi 48 jam merupakan waktu yang optimal.
KORELASI KADAR ALBUMIN, AST (ASPARTATE TRANSAMINASE) DAN ALT (ALANINE TRANSAMINASE) PADA PASIEN TUBERKULOSIS DI RSU SANTA MARIA CILACAP Sari, Windia Arta; Puspodewi, Dini; Farabi, Meka Faizal
Pharmaqueous: Jurnal Ilmiah Kefarmasian Vol. 7 No. 1 (2025): Volume 7, Nomor 1, Mei 2025
Publisher : Universitas Al-Irsyad Cilacap

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36760/jp.v7i1.628

Abstract

Tuberkulosis (TBC) adalah penyakit menular yang disebabkan oleh spesies Mycobacterium. Mycobacterium Tuberculosis, sejenis kuman berbentuk batang. Sebagian besar dinding kuman terdiri atas asam lemak (lipid), peptidoglikan dan arabinomanan yang menyebabkan kuman ini lebih tahan terhadap asam sehingga disebut bakteri tahan asam (BTA). Tujuan dari penelitian ini untuk mengetahui korelasi kadar Albumin, AST dan ALT pada pasien Tuberculosis di RSU Santa Maria Cilacap. Metode penelitian ini menggunakan studi analitik observasional dengan pendekatan cross-sectional untuk mengetahui korelasi kadar albumin, AST, dan ALT pada pasien TBC di RSU Santa Maria Cilacap ,pengambilan data menggunakan data sekunder dari Sistem Informasi Manajemen Rumah Sakit (SIM RS) pada periode September 2022 sampai dengan September 2023. Berdasarkan perhitungan rumus slovin, besar sampel yang dibutuhkan sebanyak 46 sampel. Sampel yang diambil berdasarkan teknik probability sampling tipe random sampling. Hasil penelitian menunjukkan bahwa rata-rata nilai Albumin (ALB) adalah 3.387 g/dL dengan rentang 2.110–4.690 g/dL. Rata-rata AST menunjukkan nilai yang sangat tinggi, yaitu 78.109 U/L dengan deviasi standar yang besar (158.941), yang mengindikasikan adanya pencilan atau distribusi data yang tidak normal. Demikian pula, ALT memiliki sebaran luas dari 5 hingga 605 U/L, dengan rata-rata 58.891 U/L. Hasil yang telah di uji tidak terdapat korelasi antara kadar albumin dengan AST maupun ALT, namun AST dan ALT memiliki hubungan yang signifikan dan sangat kuat (p-value < 0,001)
Pemanfaatan Tanaman Rambutan (Nephelium lappaceum L.) sebagai Bahan Eco-Print untuk Peningkatan Pengetahuan dan Ketrampilan Masyarakat Endang Tri Wahyuni Maharani; Stalis Norma Ethica; Ana Hidayati Mukaromah; Asiva Khoirunisa; Sa’if Revallindo Mirza; Dinah Fauziyyah; Iqbal Tamimi; Pepi Febrianti; Meka Faizal Farabi
JURNAL INOVASI DAN PENGABDIAN MASYARAKAT INDONESIA Vol 4 No 4 (2025): Oktober
Publisher : Fakultas Kesehatan Masyarakat, Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/jipmi.v4i4.729

Abstract

Latar Belakang: Desa Sidorejo kelurahan Tambangan kecamatan Mijen merupakan suatu desa yang banyak warganya menanam tanaman buah rambutan (Nephelium lappaceum L.), namun banyak masyarakat yang belum memiliki pengetahuan tentang manfaat tanaman tersebut sebagaibahan Eco-print. Kegiatan pengabdian kepada Masyarakat (PKM) ini merupakan implementasi hasil penelitian tentang pemanfaatan tumbuhan sebagai motif pada eco-print. Tujuan: Untuk mengedukasi masyarakat tentang manfaat daun rambutan sebagai bahan eco-print, sehingga dapat meningkatkan pendapatan Masyarakat. Metode: Kegiatan dilaksanakan di Sidorejo, Kelurahan Tambangan, Mijen Semarang dalam bentuk ceramah dan pelatihan ketrampilan Eco-print. Partisipan pengabdian masyarakat sebanyak 20 orang. Hasil: Partisipan lebih memahami tentang manfaat daun tanaman rambutan sebagai bahan eco-print.  Nilai rata-rata pengetahuan partisipan mengalami peningkatan dari 56,5 poin saat pre-test menjadi 90,25 post-test, mengalami peningkatan rerata skor pengetahuan sebesar 59,74%. Kesimpulan: Edukasi dalam bentuk ceramah dan pelatihan dapat meningkatkan pengetahuan masyarakat tentang manfaat daun tanaman rambutan dalam pembuatan Eco-print. Kata kunci: daun rambutan, eco-print, nephelium lappaceum l _________________________________________________________________________ Abstract Background: Sidorejo Village, Tambangan Subdistrict, Mijen District, is a village where many residents grow rambutan (Nephelium lappaceum L.), but no one has knowledge of the benefits as an Eco-print material. In the previous research, results on the use of plants as motifs in eco-print were presented. This community service activity is an implementation of it. Objective: To educate the community about the benefits of rambutan leaves as an eco-print material, so that it can increase community income. Method: The activity was carried out in Sidorejo, Tambangan Subdistrict, Mijen, Semarang, in the form of lectures and Eco-print skills training. Among the 20 community service participants are present. Result: Participants better understand the benefits of rambutan leaves as an eco-print material. The average knowledge score of participants increased from 56.5 points in the pre-test to 90.25 in the post-test. The average knowledge score has increased by 59.74%. Conclusion: Education by lectures and training can increase community knowledge about the benefits of rambutan leaves in making Eco-print. Keywords: rambutan leaves, eco-print, nephelium lappaceum l
DIFFERENCE IN WHITE BLOOD CELL COUNT IN STUDENTS CONSUMING HIGH-PROTEIN MILK AND THOSE NOT CONSUMING IT AT SMK MA'ARIF NU 2 AJIBARANG Adzani Azhar, Fadlilah; Farabi, Meka Faizal; Nugroho, Yusuf Eko
Jurnal Mitra Kesehatan Vol. 8 No. 02 (2026): Jurnal Mitra Kesehatan
Publisher : STIKes Mitra Keluarga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47522/jmk.v8i02.442

Abstract

Introduction : Leukocytes are an important part of the immune system that plays a role in fighting infection. Adequate protein intake, including from high-protein milk such as goat's milk, is believed to support the formation and function of leukocytes in the body. The protein, vitamin, and mineral content in goat's milk is known to play a role in supporting the immune system. This study aims to determine the difference in white blood cell counts between female students who consume high-protein goat milk and those who do not. Method: This study was conducted over a period of six months, from December to May 2025, at the TLM laboratory of SMK Ma'arif NU 2 Ajibarang. The research was conducted experimentally using a post-test only control group design on 28 female students in class XI TLM SMK Ma'arif NU 2 Ajibarang who were randomly selected using simple random sampling from the entire student population of the school, then divided into two groups, namely the treatment group (consuming high-protein goat milk) and the control group (not consuming). Data were obtained from examining the number of leukocytes using a manual method with an Improved Neubauer counting chamber. Result: The results showed that the average leukocyte count in the treatment group was 7946.43 cells/micoL, whereas in the control group it was 5885.71 cells/microL. The Independent Sample T-Test yielded a p- value rather than 0.001, which shows that there is a significant difference between the two groups. Conclusion: High consumption of protein-rich milk has a significant effect on increasing the number of leukocytes, making it a viable alternative for supporting the immune system of adolescent girls.
PERBANDINGAN KADAR HEMOGLOBIN, GLUKOSA DARAH, DAN LEUKOSIT SEBELUM DAN SESUDAH HEMODIALISA PADA PASIEN GAGAL GINJAL KRONIS KOMORBID DAN NON KOMORBID DIABETES MELLITUS DI RSPC Risma Adzkia Putri; Ira Pangesti; Meka Faizal Farabi
Klinikal Sains : Jurnal Analis Kesehatan Vol. 12 No. 2 (2024): Desember
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/klinikal_sains.v12i2.4956

Abstract

Chronic Kidney Disease (CKD) is an impairment of the glomerular organ function of the kidneys. The process of blood purification by collecting waste is called hemodialysis. The prevalence of CKD increased from 1990 to 2017 globally by 21.3% and the mortality rate increased by 41.5%. The purpose of this study was to compare hemoglobin, leukocyte, and blood glucose levels before and after hemodialysis in patients with and without comorbid Diabetes Mellitus (DM) at Pertamina Cilacap Hospital (RSPC). The method used was cross sectional using univariate and bivariate analysis with JASP program. The results showed that in CKD patients without DM, hemoglobin levels were significantly different (p<0.05) after hemodialysis. While leukocyte and glucose levels had no significant difference (p>0.05). In CKD patients with DM, there is a significant difference in hemoglobin levels (p<0.05) after hemodialysis. In addition, there is a significant difference in glucose levels (p<0.05) after hemodialysis. Meanwhile, there was no significant difference in leukocyte levels (p>0.05). Comparison of pre and post hemodialysis between CKD without DM and CKD with DM there is a significant difference (p<0.05) in hemoglobin and blood glucose levels but there is no significant difference (p>0.05) in leukocyte levels.
DIFFERENCES IN NON FASTING TRIGLICERIDE LEVELS BETWEEN 8 HOURS FASTING AND 12 HOURS FASTING Desika Dewi; Dini Puspodewi; Meka Faizal Farabi
Klinikal Sains : Jurnal Analis Kesehatan Vol. 13 No. 2 (2025): Desember
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/klinikal_sains.v13i2.6604

Abstract

Triglycerides are a type of blood fat that plays an important role in energy metabolism, but excessive levels can increase the risk of cardiovascular disease. The examination of triglyceride levels generally requires fasting, but the optimal duration of fasting is still debatable. This study aims to analyze the differences in triglyceride levels in non-fasting conditions, 8-hour fasting, and 12-hour fasting. This study is an analytical study with a cross sectional design involving 39 students of the Bachelor of Applied Medical Laboratory Technology Study Program at Al-Irsyad University Cilacap as samples. Blood was taken in three conditions: non-fasting, 8-hour fasting, and 12-hour fasting, then examined using the GPO-PAP colorimetric enzymatic method. The analysis showed that the average triglyceride level in the non-fasting condition was 104.59 mg/dL, 8-hour fasting was 91.90 mg/dL, and 12-hour fasting was 87.08 mg/dL. The results of the Paired Sample T-Test test showed that there was a significant difference between non-fasting conditions and 8-hour fasting (p = 0.009), as well as between non-fasting and 12-hour fasting (p < 0.001). However, there was no significant difference between 8-hour fasting and 12-hour fasting (p = 0.172). Based on these findings, it can be concluded that fasting for 8 hours is enough to significantly reduce triglyceride levels, so it can be considered as the minimum feasible duration for triglyceride. Keywords: Triglycerides, Non Fasting, 8 Hours Fasting, 12 Hours Fasting
PERBEDAAN PROFIL PROTEIN PADA TAHU SUTERA, TAHU KUNING DAN TAHU PONG METODE SDS-PAGE Raden Bagus Muhamad Tsabitul Fikriyansyah; Meka Faizal Farabi; Dini Puspodewi
Klinikal Sains : Jurnal Analis Kesehatan Vol. 13 No. 2 (2025): Desember
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

A food made from soybeans has a nutritional content in the form of protein, namely tofu. The principle of making tofu is made from white soybeans and the process is soaked in water, ground until smooth, boiled, filtered then separate the tofu dregs and filtrate (water) and added coagulants and food additives (BTP) then molded, but there are differences in the process of making tofu. Silken tofu has a soft texture and the process of making the curd is not pressed and not separated from the liquid so it resembles jelly. Yellow tofu has a yellow color from the addition of turmeric juice solution in the manufacturing process and its dense texture. Pong tofu has a distinctive feature after the manufacturing process is fried first before being packaged. To determine the differences in protein profiles, protein profile analysis was carried out using the SDS-PAGE method, for samples of silken tofu, yellow tofu and raw pong tofu. This type of research is descriptive analytical. The first analysis of total protein content with a standard curve and using a UV-Vis spectrophotometer, then continued with protein profile analysis using an SDS-PAGE electrophoresis tool. Results of total protein content and protein profile Silken tofu has a total protein content of 0.63 µg/µL and 1 protein band. Yellow tofu has a total protein content of 0.79 µg/µL and 2 protein bands. Pong tofu has a total protein content of 1.10 µg/µL and 4 protein bands. The difference in the process of the three tofus can affect the protein content of tofu, which can increase or decrease
PENGARUH PERBANDINGAN ANTIKOAGULAN EDTA DAN VOLUME DARAH YANG TIDAK SESUAI PADA PEMERIKSAAN HEMOGLOBIN, ERITROSIT, DAN TROMBOSIT PADA PASIEN MEDICAL CHECK UP DI RS PERTAMINA CILACAP Kartika Palupi; Meka Faizal Farabi; Dini Puspodewi
Klinikal Sains : Jurnal Analis Kesehatan Vol. 13 No. 2 (2025): Desember
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Medical Check Up (MCU) is a procedure intended to determine the overall health condition. The results of this examination can be a reference for companies to measure the physical ability of employees to perform tasks. The purpose of this study was to determine the effect of the use of EDTA anticoagulant that was not in accordance with blood volume on the examination of hemoglobin, erythrocytes, and platelets in Medical Check Up patients at RSPC. The research sample was taken using purposive sampling technique consisting of 33 Medical Check Up patients.This study is an observational analytic study with cross sectional method. The results showed that the average hemoglobin level of 2 ml blood volume in EDTA vacutainer tubes was 15.488 g/dL while the average hemoglobin level of 3 mL blood volume in EDTA vacutainer tubes was 15.515 g/dL and the Paired Sample T-Test test showed no significant difference (p>0.05). The average erythrocyte level of 2 ml blood volume in EDTA vacutainer tubes is 5.518 million /µL, while the average erythrocyte level of 3 mL blood volume in EDTA vacutainer tubes is 5.117 million /µL and the Paired Sample T-Test test shows no significant difference (p>0.05). The average platelet level of 2 ml blood volume in EDTA vacutainer tubes is 274.576 thousand/µL while the average platelet level of 3 mL blood volume in EDTA vacutainer tubes is 267.970 thousand/µL and from the Wilcoxon Signed Rank Test which shows that there is a significant difference in platelet levels (p<0.05).
EFEK IMUNOMODULATOR EKSTRAK DAUN ASAM JAWA (Tamarindus indica L) TERHADAP JUMLAH DAN JENIS SEL LEUKOSIT PADA MENCIT BALB/C YANG DIINFEKSI BAKTERI Salmonella Typhi mala aulia hapsari; Meka Faizal Farabi
Klinikal Sains : Jurnal Analis Kesehatan Vol. 13 No. 2 (2025): Desember
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/klinikal_sains.v13i2.6705

Abstract

Typhoid fever is an acute infectious disease caused by Salmonella typhi germs, mainly affecting the digestive tract with symptoms of fever for more than 7 days. In Indonesia alone, the incidence rate for this disease is estimated to be around 300-810 cases per 100,00 population per year. Tamarind leaves with flavonoid content can inhibit anti-inflammatory activity. This study aims to determine the immunomodulatory effect of tamarind leaf extract (Tamarindus indica L). Against the number and type of leukocyte cells in balb/c mice infected with Salmonella typhi bacteria. In this study using the experimental group method of Balb/c male mice. Pure form (Tamarindus indica L.) shows immunomodulatory activity such as an increase in the number and type of leukocytes. The research sample was 25 Balb/c male mice weighing 20-30 grams which were then divided into 5 treatment groups. The dose variation is 50 mg/kg BW, 75 mg/kg BW, and 100 mg/kg BW orally for 6 days. Then on day 7 was infected using Salmonella typhi bacteria. Statistical test results showed that the dose groups of 50, 75, and 100 mg/kg BW were not significantly different from the negative control (p>0.05).
Co-Authors Adzani Azhar, Fadlilah Afrilla, Rananda Ana Hidayati Mukaromah Asiva Khoirunisa BUDIYANTO Damara Desiyanti Desika Dewi Dinah Fauziyyah Dini Puspodewi Dwi Sulistyowati Elisa Issusilaningtyas Endang Tri Wahyuni Maharani Fery Nugroho Fitri Galih Ramadhani Fitria Nur Kartika Ginanjar Triyono, Heru Hastuti Budi Rahayu Imam Agus Faizal Iqbal Tamimi Ira Pangesti Ira Pangesti Iskandar, Drajat Junior Dwi Cahyo Kartika Palupi Legiana Elza Syariah Lestari, Tika Lisa Savitri mala aulia hapsari Mubarok, Akhmad Mulyani, Eti Nikmah Nuur Rochmah Nugroho, Yusuf Eko Pepi Febrianti Putri, Reza Amelia Raafi R, Muhammad Raden Bagus Muhamad Tsabitul Fikriyansyah Reja Rafli, Afan Risma Adzkia Putri Sari, Windia Arta Sa’if Revallindo Mirza Sri Lestari Stalis Norma Ethica Tajudin, Tatang wahid, wahyumuttaqin Wahyu, Wahyu Wahid Muttaqin Yasinta Aritonang Yuhansyah Nurfauzi Yusuf Eko Nugroho Yusuf Eko Nugroho