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All Journal Pharmascience JOPS (Journal Of Pharmacy and Science) Jurnal Pengabdian Masyarakat (ABDIRA) Jurnal Bakti Untuk Negeri Safari : Jurnal Pengabdian Masyarakat Indonesia Sains Medisina Jurnal Pengabdian Masyarakat Panacea
Hayatun Izma
Universitas Lambung Mangkurat
Aerospace Engineering Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Journal : Pharmascience

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Uji Sun Protection Factor (SPF) Ekstrak Etanol Daun Mitragyna speciosa Korth. Normaidah Normaidah; Maulidya Najahidin; Maslia Rahmah; Fadlilaturrahmah Fadlilaturrahmah; Hayatun Izma
Jurnal Pharmascience Vol 10, No 2 (2023): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v10i2.17038

Abstract

Kratom (Mitragyna speciosa Korth.) merupakan tanaman tropis yang memiliki kemampuan melindungi kulit dari paparan sinar matahari. Tujuan dari penelitian ini adalah untuk mengetahui aktivitas tabir surya ekstrak etanol daun M. speciosa kuantitatif menggunakan spektrometri UV-Vis. Ekstraksi dilakukan dengan metode maserasi menggunakan pelarut etanol 96%. Kandungan metabolit sekunder secara kualitatif dilakukan menggunakan skrining fitokimia. Aktivitas tabir surya diuji menggunakan lambda 290-320 nm dengan interval 5 nm. Ekstrak etanol daun M. speciosa diperoleh sebesar 86,09 gram (17,218%) dan pada konsentrasi 250 ppm menunjukkan adanya aktivitas tabir surya dengan nilai SPF sebesar 8,433. Daun kratom asal Kalimantan Selatan berpotensi sebagai produk kosmetik tabir surya. Kata Kunci: Kratom, Spektrofotometri UV-Vis, Tabir Surya, Flavonoid Kratom (Mitragyna speciosa Korth.) is a tropical plant that has the ability to protect the skin from sun exposure due to the presence of flavonoids. The purpose of this study was to determine the sunscreen activity of the M. speciosa leaves ethanolic extract, quantitatively by UV-Vis spectrometry. Extraction was carried out by maceration method in 96% ethanol. The content of secondary metabolites were qualitatively determined using the phytochemistry screening study. The sunscreen activity was tested using 290-320 nm (5 nm intervals). The ethanol extract of M. speciosa leaves was obtained by 86.09 grams (17.218%) and with a concentration of 250 ppm showed sunscreen activity with an SPF value of 8.433. Kratom leaves from South Kalimantan have potential as a sunscreen.
In Vitro Study of Antibacterial Activity of Patindis Leaf Extract (Urophyllum arboreum) and Microneedle Acne Patch against Propionibacterium acnes and Staphylococcus aureus Hayatun Izma; Deni Setiawan; Putri Helena Junjung Buih; Khoirunnisa Muslimawati; Naila Azizah; Mahfuzatul Ajmi
Journal of Pharmascience Vol 13, No 1 (2026): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v13i1.24008

Abstract

Acne vulgaris is a cutaneous disorder associated with Propionibacterium acnes and Staphylococcus aureus. This study investigated the antibacterial activity of patindis leaf extract (Urophyllum arboreum) and its microneedle acne patch against both bacteria. The extract was prepared from dried simplicia by maceration using 96% ethanol. Phytochemical screening was conducted using test-tube methods. Antibacterial testing included determination of inhibition zone diameter using the well-diffusion method, as well as the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). Clindamycin 1% was used as a positive control, while 20% DMSO and microneedle patches without extract served as negative controls. The U. arboreum leaf extract contained flavonoids, alkaloids, saponins, condensed tannins and terpenoids. At concentrations of 1.25%, 2.5%, and 5%, the extract produced inhibition zones of 12.368, 14.693, 18.403 mm against P. acnes and 14.523, 17.408, 18.840 mm against S. aureus, respectively. The MIC and MBC values against both bacteria were 0.625%. The microneedle acne patch formulations produced inhibition zones of 9.196 mm (F1), 10.140 mm (F2), and 10.713 mm (F3) against P. acnes, but showed no activity against S. aureus. These results indicate that the microneedle acne patch containing U. arboreum leaf extract has potential as an alternative topical antibacterial agent.
Co-Authors Alya Zainah Angelina Ayu Dela Anna Humaira Anna Khumaira Sari Ayu Shafira Razakhi Bayu Wiratama Buih, Putri Helena Junjung Damayanti Rumondang Butar Butar Daniel Wisnugroho Deni Setiawan Difa Intannia Dinna Fitria Kumala Dyah Anggraeni Fadlilaturrahmah Fadlilaturrahmah, Fadlilaturrahmah Fitria Handayani Fitriana Rahmi Gusti Nisa Soleha Hema Novita Redanti Hema Novita Redanti2 Henny Maryani Herningtyas Nautika Lingga Khoerul Anwar Khoirunnisa Muslimawati Laode Muhammad Indra Kesuma Laura Sarwo Liling Triyasmono LINDA WAHYUNI Lukman Mahdi Lukman Mahdi2 Mahfuzatul Ajmi Maslia Rahmah Maulidya Najahidin Melda Muhammad Ikhwan Rizki Murni Novita Eka Sari Mutia Mawaddah Nadya Rahmi Nahdiya Nahdiya Naila Azizah Nasya Hafizah Nazhipah Isnani Noor Amini Budiarti Normaidah, Normaidah Nurul Savira Fahira Okta Muthia Sari Prima Happy Ratnapuri Putra, Aditya Maulana Perdana Rahmatullah, Satrio Wibowo Samsul Hadi Samsul Hadi2 Sandi, Dita Ayulia Dwi Siti Malahayati Sofia