Article Per Year (5 Year)
p-Index From 2021 - 2026
1.896
P-Index
This Author published in this journals
All Journal PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Promotif Preventif Jurnal Kesehatan Tambusai Heca Journal of Applied Sciences Malacca Pharmaceutics Mapalus Nursing Science Journal (MNSJ): Jurnal Ilmu Keperawatan Mapalus Indonesian Journal of Case Reports Grimsa Journal of Science Engineering and Technology
Niode, Nurdjannah Jane
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Earth & Planetary Sciences Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Physics Public Health

Published : 12 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 12 Documents
Search

 1   2 
Hubungan antara Pengetahuan dan Sikap Masyarakat dengan Perilaku Pencegahan Demam Berdarah Dengue di Wilayah Kerja Puskesmas Tompaso Momongan, Merry Vike; Niode, Nurdjannah Jane; Katuuk, Mario Esau
Mapalus Nursing Science Journal Vol. 3 No. 1 (2025): Mapalus Nursing Science Journal (Jurnal Ilmu Keperawatan Mapalus)
Publisher : Program Studi Ilmu Keperawatan Fakultas Kedokteran Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/mnsj.v3i1.60346

Abstract

Background: Dengue Hemorrhagic Fever is an endemic disease in Indonesia, significantly influenced by community prevention behavior. Knowledge and attitudes are the main factors in the low effectiveness of prevention behavior. Objective: This study aims to analyze the relationship between the level of knowledge and attitude of the community with dengue prevention behavior of DHF in the working area of Puskesmas Tompaso. Research Methods: This study used a descriptive design with a cross-sectional approach. A total of 221 respondents was randomly selected using convenience sampling. Data were collected through questionnaires and analyzed using spearman correlation test. Results: There is a significant relationship between knowledge and prevention behavior with a correlation value of r = 0,748 and a p-value = 0,000 and there is a relantionship between attitudes and prevention behavor with a correlation value of r =0 ,889 with a p-value = 0,000. Conclusion: Community knowledge and attitudes contribute to better behavior. The better the knowledge and attitude of the community will affect good behavior as well. Keywords: dengue demorrhagi fever, knowledge, attitudes, prevention behavior
Mechanistic Exploration of Moringa oleifera Leaf Bioactives in Prostate Cancer Using Network Pharmacology Tengke, Feniea Wulan Agaype; Tallei, Trina Ekawati; Turalaki, Grace Lendawati Amelia; Tendean, Lydia Estelina Naomi; Kaseke, Martha Marie; Niode, Nurdjannah Jane; Fatimawali, Fatimawali
Grimsa Journal of Science Engineering and Technology Vol. 4 No. 1 (2026): April 2026
Publisher : Graha Primera Saintifika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61975/gjset.v4i1.105

Abstract

Prostate cancer remains one of the most prevalent malignancies in men worldwide, while current therapeutic strategies are often associated with adverse effects and the emergence of drug resistance, highlighting the need for safer and more effective alternatives. This study aimed to elucidate the multitarget molecular mechanisms of bioactive compounds derived from Moringa oleifera leaves against prostate cancer using an integrated in silico network pharmacology approach. A total of 137 bioactive compounds were collected from LC–MS/MS profiling data and phytochemical databases, of which 20 compounds with high predicted biological activity were prioritized based on Way2Drug PASS analysis. Potential protein targets were predicted and intersected with prostate cancer–associated genes to identify shared targets. Protein–protein interaction network analysis revealed 536 overlapping targets, with ten hub proteins, ESR1, AKT1, SRC, EGFR, TP53, HSP90AA1, PIK3CA, HSP90AB1, PIK3R1, and MAPK1, identified as central nodes. Pathway enrichment analysis demonstrated that these targets were predominantly involved in cancer-related signaling pathways, including pathways associated with EGFR tyrosine kinase inhibitor resistance. Pharmacokinetic and toxicity assessments indicated that several compounds, such as isorhamnetin, kaempferol, tocopherol, and afzelin, exhibited favorable drug-likeness properties and low predicted toxicity. Overall, these findings suggest that bioactive compounds from Moringa oleifera leaves exert anticancer effects through a multitarget and multi pathway mode of action rather than single-protein modulation. This study provides systematic insight into the molecular mechanisms underlying the anti–prostate cancer potential of Moringa oleifera leaves and supports their relevance as candidates for further experimental validation and drug development.
Co-Authors Alexander S. L. Bolang Andika, Agustinus B H. R. Kairupan Barasarathi , Jayanthi Celik, Ismail Dina Rombot Earlia, Nanda Fatimawali . Gunawan, Deni Husdayanti, Noviana Jimmy Posangi Jootje M. L. Umboh Kapantow, Nova Helen Kapantow, Nova Hellen Katuuk, Mario Esau Kepel, Billy Johnson Korompis, Grace Esther Caroline Mahono, Charles Kurnia Malla, Anastasia Manampiring, Aaltje Ellen Martha Marie Kaseke Maulana, Aga Momongan, Merry Vike Muhammad Subianto Nova Hellen Kapantow Regina, Senduk Cindy Rinaldi Idroes Rungkat, Timotius A. Sasmita, Novi Reandy Subadio, Nathanael Yngwie Christian Suhendra, Rivansyah Suryadi Suryadi Tendean, Lydia Estelina Naomi Tengke, Feniea Wulan Agaype Teuku Rizky Noviandy Thambas, Arthur Harris TRINA EKAWATI TALLEI Turalaki, Grace Lendawati Amelia Wijaya, Natalya Wungouw, Herlina Ineke Surjane