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Toxicity Test of Flavonoid Compounds from Ethyl Acetate Extract of Malacca Leaves with Brine Shrimp Lethality Test Zakwan, Muhammad; Sutriana, Amalia; Nurliana, Nurliana; Asmilia, Nuzul; Ammar, Muhammad; Novianti, Arindita Niatazya
Jurnal Medik Veteriner Vol. 6 No. 3 (2023): Special Issue: International Conference on Veterinary Medicine and Health Scien
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jmv.vol6.iss3.2023.15-19

Abstract

Flavonoids are a group of polyphenolic compounds produced in plants as secondary metabolites. Flavonoids have favorable biochemical effects on multiple diseases and other bioactivities. This study aimed to isolate the active compounds contained in malacca (Phyllanthus emblica) leaves and analyze toxic properties using the Brine Shrimp Lethality Test (BSLT) method in Artemia salina leach shrimp larvae. This study used malacca leaf powder with ethyl acetate solvent then macerated. Ethyl acetate extract was concentrated and fractionated, then toxicity tests were carried out. Extracts from the evaporation results were further fractionated using solvent petroleum ether, diethyl ether, and ethyl acetate. Then the ethyl acetate fraction was hydrolyzed using reflagged with 7% sulfuric acid for two hours, then the filtrate was extracted with ethanol solvent. The obtained fraction washed with aquades and dried using a vacuum desiccator. The toxicity test results showed that the flavonoid compound of malacca leaves was not toxic with a value of LC50 > 1000 ppm, an increase in the concentration of the extract was followed by an increase in the average mortality of larvae.
Pathological Impacts Due to The Existence of Plastic Waste in Rumen of Bali Cattle Berata , I Ketut; Susari, Ni Nyoman Werdi; Kardena, I Made; Novianti, Arindita Niatazya
Jurnal Medik Veteriner Vol. 6 No. 3 (2023): Special Issue: International Conference on Veterinary Medicine and Health Scien
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jmv.vol6.iss3.2023.26-30

Abstract

This study aimed to determine the prevalence of Bali cattle rumen containing plastic waste and its impact on tissues and health risks. A total of 100 Bali cattle were investigated after being slaughtered at several traditional slaughterhouses in Denpasar City. Rumen samples were examined for any plastic waste, meanwhile blood, liver, kidney, lungs, spleen, intestine, and myocardium were collected for evaluation of heavy metals content and histopathological examination. The heavy metal measurement was performed using the atomic absorption spectrophotometry (AAS) method. Those tissues for histopathological examination were fixed in buffer neutral formalin (BNF) and then evaluated using hematoxylin-eosin (HE) staining. The results of the examination reported 9 rumens (9%) containing plastic waste. The hematological profile showed leucocytosis and the content of lead (0.841 ± 0.522 ppm). Histopathological changes in the liver, kidneys, lungs, spleen, and intestine, were found in various types of degeneration, inflammation, and mild necrosis. In conclusion, the prevalence of plastic waste in the rumen of Bali cattle was 9%, with leucocytosis, lead content was 0.841 ± 0.522 ppm, and various histopathological lesions such as congestion, inflammation, and fatty degeneration in parenchymous tissues.
Peripheral Blood Smear Analysis for Cattle with Foot and Mouth Diseases in Lembang, West Bandung Septiyani, Septiyani; Majid, Rully Abiyoga; Gradia, Resty; Setiawan, Iyus; Yantini, Puji; Novianti, Arindita Niatazya
Jurnal Medik Veteriner Vol. 6 No. 3 (2023): Special Issue: International Conference on Veterinary Medicine and Health Scien
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jmv.vol6.iss3.2023.8-14

Abstract

Foot and Mouth Disease (FMD) is an infectious disease that is endemic and has a significant impact on dairy farming in Indonesia. In reducing the impact caused by FMD, proper handling by veterinarians is necessary. The peripheral blood smear can be used as a data reference to give priority to the right treatment for cattle with FMD. This study aimed to describe the appearance of peripheral blood smears in cattle with FMD. The study data were obtained from 15 cattle with FMD at KPSBU Lembang, West Bandung, West Java, Indonesia. The morphological profile of the blood was examined using the peripheral blood smear method. Morphological abnormalities found in the peripheral blood smear of red blood cells were anisocytosis (microcytosis and macrocytosis), poikilocytosis (achanthocytosis and echinocytosis), and hypochromasia. Different morphological abnormalities of leukocytes can be caused by anorexia due to FMD secondary to lack of nutritional intake. To determine an effective and efficient treatment, it is recommended that veterinarians refer to the results of this study.
EXTENSION AND TRAINING ON ANIMAL REPRODUCTIVE HEALTH AND ANIMAL FEED NUTRITION IN PENDEM VILLAGE, NGARIBOYO, MAGETAN Hidayatik, Nanik; Lamid, Mirni; Hermadi, Herry Agoes; Warsito, Sunaryo Hadi; Al 'Arif, Mohammad Anam; Hestianah, Eka Pramyrtha; Novianti, Arindita Niatazya; Rosyada, Zulfi Nur Amrina; Sabdoningrum, Emy Koestanti
Jurnal Layanan Masyarakat (Journal of Public Services) Vol. 9 No. 2 (2025): JURNAL LAYANAN MASYARAKAT
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/.v9i2.2025.166-178

Abstract

Pendem Village, Ngariboyo District, Magetan Regency is one of the villages that has the potential for cattle farming. However, cattle breeders in Pendem Village have problems, namely the high incidence of repeated mating in females mated through artificial insemination (AI) and the lack of availability of animal feed in the dry season. The solutions offered in this activity are (1) increasing the knowledge of BUMDes Tirto Mulyo Pendem cattle breeders about cattle reproductive disorders and (2) processing agricultural waste as animal feed in Pendem Village. The output target to be achieved is to increase the understanding of breeders regarding the reproduction of beef cattle and how to process it by making haylage and fermenting agricultural waste. The method used to achieve these output targets is through 2 stages, namely counseling and training. Based on the results of the pre- and post-test, it shows that there is an increase in the knowledge and abilities of breeders related to reproduction and processing of feed derived from agricultural waste, detection of estrus in female cattle, reporting on reproductive health disorders in cattle, causes and symptoms of reproductive disorders in female cattle, the importance of vaccination and animal health programs, cleanliness of pens, cleanliness of individual cattle and fermentation of feed shows an increase in participants who are very knowledgeable from around 0% - 15% to around 4% - 20.7%, it is expected to support the productivity of beef cattle in Pendem Village.
Effect of Excessive Carrot Juice (Daucus carota) Administration on Uric Acid and Blood Glucose Levels in Rats (Rattus norvegicus) An, Chau Yu; Kumar, Bhagya Laxmi Ramesh; Gunalan, Jheevanesh; Rajendaran, Harvina; Al Thalhah, Muhammad Rafsa; Hidayatik, Nanik; Novianti, Arindita Niatazya
Journal of Basic Medical Veterinary Vol. 14 No. 1 (2025): Journal of Basic Medical Veterinary, June 2025
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbmv.v14i1.66784

Abstract

The consumption of carrot juice (Daucus carota) has been associated with various health benefits, yet its effects on metabolic parameters such as uric acid and blood glucose levels remain inadequately explored. Understanding these effects is crucial for developing dietary recommendations, particularly for conditions related to elevated uric acid and blood glucose. This research aimed to investigate the impact of excessive carrot juice administration on uric acid and blood glucose levels in rats (Rattus norvegicus). The study sought to determine whether carrot juice could serve as a beneficial dietary intervention or if it posed risks for metabolic dysregulation. A true experimental design was employed, utilizing a post-test only control group approach. Four healthy rats were divided into two groups: a control group receiving standard rat feed and a treatment group receiving carrot juice alongside their feed for seven days. Blood samples were collected after a 12-hour fasting period, and uric acid and blood glucose levels were measured using an Easy Touch GCU glucometer. Statistical analysis included descriptive statistics and T-tests to assess significant differences between groups. The results indicated that excessive administration of carrot juice significantly decreased uric acid levels in the treatment group compared to the control group (p < 0.05). Conversely, blood glucose levels were found to be significantly higher in the treatment group (p < 0.05), suggesting a complex interaction between carrot juice consumption and metabolic regulation. The study concludes that while excessive carrot juice can effectively lower uric acid levels in rats, it may also lead to increased blood glucose levels. These findings highlight the need for cautious dietary recommendations regarding carrot juice intake, particularly for individuals at risk of hyperglycemia. Future research should focus on larger sample sizes and explore the effects of carrot juice on various physiological systems and stress-related impacts on metabolic parameters.
The Effect of Turmeric (Curcuma domestica) And Papaya Leaves (Carica papaya L.) As Feed Additives on Yolk Color and Yolk Index of Quail Eggs (Cortunix-cortunix japonica) Novianti, Arindita Niatazya; Rimayanti, Rimayanti; Estoepangestie, A.T. Soelih; Lamid, Mirni; Widjaja, Made Ngakan Rai
Jurnal Agro Veteriner Vol. 8 No. 2 (2025): Jurnal Agro Veteriner
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/agrovet.v8i2.74064

Abstract

The objective of this research was to investigate the effects of turmeric (Curcuma domestica) and papaya leaves (Carica papaya L.) on the yolk color and yolk index of quail eggs (Coturnix coturnix japonica). A total of 24 laying quails were divided into four treatment groups: P0 (standard feed), P1 (feed supplemented with 0.6% turmeric), P2 (feed supplemented with 0.25% papaya leaves), and P3 (feed supplemented with 0.6% turmeric and 0.25% papaya leaves). Yolk color and yolk index measurements were conducted by breaking open the eggs. The yolk color was assessed by comparing the egg yolk with a standardized yolk color fan to identify the closest match. The yolk index was determined by measuring the width of the yolk with calipers and the height of the yolk using a micrometer tripod. Analysis of variance (ANOVA) revealed significant differences among the treatment groups (p < 0.05). The effects of turmeric (Curcuma domestica) and papaya leaves (Carica papaya L.) significantly increased the yolk color and yolk index of quail eggs (Coturnix coturnix japonica).