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All Journal MPI (Media Pharmaceutica Indonesiana) Jurnal Farmasi dan Sains Indonesia (JFSI) Jurnal Kesehatan Amanah Journal of Pharmaceutical and Sciences. MULTIPLE: Journal of Global and Multidisciplinary Scientica: Jurnal Ilmiah Sains dan Teknologi Science and Community Pharmacy Journal
Anak Agung Pradnya Paramitha Vidiani
STIKES Telogorejo Semarang
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Penyuluhan Dan Pencegahan Penyakit Gastritis Pada Masyarakat Kelurahan Krobokan Kota Semarang Madyo Adrianto; Anisa Nova Puspitaningrum; Anak Agung Pradnya Paramitha Vidiani; Valentina Girsang
MULTIPLE: Journal of Global and Multidisciplinary Vol. 2 No. 8 (2024): Agustus
Publisher : Institute of Educational, Research, and Community Service

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Abstract

Gastritis adalah kondisi peradangan pada mukosa lambung yang dapat bersifat akut, kronis, atau lokal. Penyebabnya bisa meliputi infeksi bakteri *Helicobacter pylori* atau konsumsi makanan yang merusak mukosa pelindung lambung. Pengabdian masyarakat ini bertujuan untuk memberikan wawasan kepada masyarakat di Kelurahan Krobokan, Semarang, mengenai penyakit gastritis dan cara pencegahannya yang tepat. Kegiatan penyuluhan penyakit gastritis dilaksanakan di rumah warga RT.06/RW.13 Kelurahan Krobokan Kecamatan Semarang Barat pada tanggal 01 April 2024. Metode penyuluhan dan pencegahan penyakit gastritis menggunakan leaflet dengan menjelaskan materi serta diskusi tanya jawab dengan peserta. Penyuluhan berjalan dengan baik, dan peserta mampu memahami materi serta pengetahuan mengenai penyakit gastritis dan cara pencegahannya
ANALISIS EFEK KONSENTRASI EKSTRAK DAUN SIRIH CINA (Peperomia Pellucida L.) SEBAGAI ANTIBAKTERI Staphylococcus Aureus dan Propionibacterium acnes Girsang, Valentina; Widiasari , Anggun; Rustaman , Heri; Saptawati , Tunik; Puspitaningrum , Anisa Nova; Vidiani , Anak Agung Pradnya Paramitha
Scientica: Jurnal Ilmiah Sains dan Teknologi Vol. 2 No. 11 (2024): Scientica: Jurnal Ilmiah Sains dan Teknologi
Publisher : Komunitas Menulis dan Meneliti (Kolibi)

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Abstract

Acne vulgaris merupakan infeksi kulit yang umum terjadi, dengan tingkat kejadian berkisar sekitar 80-100%. Kondisi kulit ini dapat dikaitkan dengan proliferasi bakteri Staphylococcus aureus dan Propionibacterium acnes. Daun sirih cina (Peperomia pellucida L.) telah menunjukkan efek penghambatan pada pertumbuhan bakteri, khususnya terhadap Staphylococcus aureus dan Propionibacterium acnes. Tujuan dari penelitian ini adalah untuk menilai aktivitas antibakteri ekstrak daun sirih cina terhadap bakteri ini. Aktivitas antibakteri dievaluasi menggunakan metode difusi agar dengan cakram kertas. Analisis fitokimia mengungkapkan adanya flavonoid, tanin, dan saponin dalam daun sirih cina. Uji antibakteri ekstrak menunjukkan penghambatan bakteri yang signifikan. Zona penghambatan rata-rata ekstrak daun sirih cina terhadap Propionibacterium acnes adalah 8,74 mm pada konsentrasi 5%, 10,936 mm pada konsentrasi 10%, dan 15,67 mm pada konsentrasi 15%. Demikian pula, zona penghambatan terhadap Staphylococcus aureus adalah 8,341 mm pada konsentrasi 5%, 11,065 mm pada konsentrasi 10%, dan 14,293 mm pada konsentrasi 15%.
Kajian Continuity of Care Pasien Program Rujuk Balik di Puskesmas Kota Surabaya Vidiani, Anak Agung Pradnya Paramitha; Aditama, Lisa; Lorensia, Amelia
MPI (Media Pharmaceutica Indonesiana) Vol. 5 No. 1 (2023): JUNE
Publisher : Fakultas Farmasi, Universitas Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24123/mpi.v5i1.5484

Abstract

Pasien penyakit kronis menjalani transisi pelayanan kesehatan, sehingga kesinambungan perawatan atau continuity of care (CoC) menjadi komitmen antar tenaga kesehatan. CoC diukur dari perspektif pasien berdasarkan pengalaman dalam pelayanan kesehatan terkait kesinambungan informasi, hubungan dan manajerial. Tujuan penelitian adalah melakukan kajian CoC pasien DM tipe 2 dan hipertensi PRB Puskesmas Kota Surabaya dan menggali pengalaman pasien dalam transisi pelayanan kesehatan. Rancangan penelitian adalah mixed methods. Sampel ditentukan secara purposive dengan memperhatikan kriteria penelitian. Pengumpulan data dilakukan dengan menggunakan kuesioner Cuestionario Continuidad Asistencial Entre Niveles de Atencion (CCAENA) dan wawancara semi-terstruktur. Kesinambungan hubungan berada pada tingkat yang tertinggi, dimana hubungan dengan dokter spesialis lebih tinggi (95%) dibandingkan dokter umum (74%). Ketidaksinambungan hubungan terbesar, yaitu tidak bisa berkonsultasi dengan dokter yang sama di Puskesmas (58%). Kesinambungan manajerial terkait koherensi perawatan (91%) dan aksesibilitas (79%). Ketidaksinambungan manajerial terbesar adalah tidak ada koherensi perawatan antara dokter spesialis dan dokter di Puskesmas (85%) serta aksesibilitas saat antri di rumah rakit (48%). Kesinambungan informasi berada pada tingkat paling rendah (73%). Ketidaksinambungan informasi terbesar adalah diskusi antara pasien dan dokter di Puskesmas terkait pengobatan setelah rujukan (37%). Kesimpulan dari penelitian ini adalah ketidaksinambungan dalam transisi perawatan pasien penyakit kronis terbesar adalah pemberian informasi. Apoteker memiliki peran penting untuk meningkatkan pelayanan informasi dan menjamin keselamatan pasien disetiap rantai perawatan. Transition of healthcare increases the risk of chronic disease patients, therefore continuity of care (CoC) is needed for patient care. CoC measure from the patient's perspective based on experience related to continuity of information, relationships and managerial. The purpose was to study of CoC patients with type 2 diabetes mellitus (T2DM) and hypertension referral program at the Surabaya City Public Health Center and explore patient experiences in transitioning health services. The design is mixed methods. The sample was determined purposively by observe into research criteria. Data collection was using the Cuestionario Continuidad Asistencial Entre Niveles de Atencion (CCAENA) questionnaire and semi-structured interviews. Relation continuity is the highest level, where relationships with specialist are higher (95%) than general prescriber (GP) (74%). The biggest discontinuity is not being able to consult the same GP (58%). Managerial continuity related to coherence of care (91%) and accessibility (79%). The biggest managerial discontinuity is coherence between specialist and GP (85%) and accessibility when queuing at the hospital (48%). Information continuity is the lowest level (73%). The biggest discontinuity is discussion between patients and GP regarding treatment after referral (37%). Conclusion this study is the biggest discontinuity in the transition of care for chronic disease patients is information. Pharmacists have an important role to improve information services and ensure patient safety.
Evaluasi Peresepan Antibiotik pada Pasien ISPA Pediatri Metode ATC/DDD Anak Agung Pradnya Paramitha Vidiani; Livania Indri Aswara; Madyo Adrianto; Anisa Devi Kharisma Wibowo
Jurnal Kesehatan Amanah Vol. 7 No. 2 (2023): Oktober: Jurnal Kesehatan Amanah
Publisher : Universitas Muhammadiyah Manado

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57214/jka.v7i2.735

Abstract

Acute Respiratory Infections (ARI) are infectious diseases that cause the highest mortality rate in children. Antibiotics are administered to ARI patients if the infection is caused by bacteria. Excessive use of antibiotics increases the risk of resistance and irrational antibiotic use. Efforts to prevent antibiotic resistance and irrational use include evaluating antibiotic utilization based on WHO recommendations, specifically using ATC/DDD classification system and the DU90% method. This study aims to determine the antibiotic utilization profile, DDD/1000 patient-days, and DU90% among pediatric ARI from January 2022 to December 2023. This study employs a quantitative research method with retrospective data collection. The results indicate that the highest antibiotic class used was penicillin (98%), with Amoxicillin 500 mg being the most commonly prescribed antibiotic (98%). The most prevalent ARI diagnosis was Acute Pharyngitis (J.02) (66.1%). The most frequently used dosage form was syrup (54.7%), and the average duration of therapy was 3–5 days. The total antibiotic consumption was 137.4 DDD/1000 patient-days, with antibiotics included in the DU90% segment being Amoxicillin 500 mg (102.3 DDD/1000 patient-days) and Amoxicillin 250 mg (21.6 DDD/1000 patient-days). This study highlights that the most widely used antibiotic in terms of quantity was Amoxicillin 500 mg (102.3 DDD/1000 patient-days).
Edukasi Pengobatan Mandiri pada Penyakit Maag dengan Dapat Gunakan Simpan Buang (DAGUSIBU) di Kelurahan Krobokan, Kota Semarang Anisa Nova Puspitaningrum; Madyo Adrianto; Anak Agung Pradnya Paramitha Vidiani; Valentina Girsang; Fransisca Gloria
urn:multiple://2988-7828multiple.v3i39
Publisher : Institute of Educational, Research, and Community Service

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Abstract

Kegiatan edukasi dikemas dalam pengabdian masyarakat yang menerapkan metode DAGUSIBU bertujuan untuk meningkatkan kesadaran masyakarat terhadap pengunaan obat-obatan, salah satunya adalah obat-obatan Maag. Metode pengabdian dilakukan dengan cara edukasi secara langsung, egiatan ini diikuti masyarakat Kelurahan Krobokan, Kota Semarang sebanyak 18 orang perwakilan RT di Tahun 2024. Hasil dari kegiatan pengabdian ini, masyarakat dapat memperoleh informasi tambahan cara pengobatan mandiri terhadap penyakit maag. Kesimpulan dari kegiatan ini masyarakat Kelurahan Krobokan, Kota Semarang mengetahu bagaimana cara menggunakan obat dengan baik dan mencegah terjadinya efek sampingyang tidak diinginkan. Saran untuk pengabdian selanjutnya agar lebih memperhatikan edukasi penggunaan obat secara mandiri.
LITERATURE REVIEW : Cost Effective Analysis of Sitagliptin for the Treatment of Diabetes Mellitus Type 2 Vidiani, Anak Agung Pradnya Paramitha; Puspitaningrum, Anisa Nova; Girsang, Valentina; Adrianto, Madyo
Science and Community Pharmacy Journal Vol. 3 No. 1 (2024): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v3i1.546

Abstract

Diabetes mellitus (DM) is a chronic disease characterized by increased glucose levels in the blood. The prevalence of type 2 DM is currently increasing. In pharmacological treatment, metformin is the first-line oral therapy for most patients with type 2 diabetes. Therapy with targeted incretin has been shown to stimulate glucose-dependent insulin secretion, reduce glucagon secretion, improve beta cell function, slow gastric emptying, increase satiety, reduce appetite, and provide general benefits beyond the pancreas. Search for scientific articles by utilizing internet searches through Google Scholar and PubMed. Using keywords related to "Cost Effective Analysis", "Diabetes Mellitus type 2", "Sitagliptine" with Boolean operator "AND". Sitagliptin is less cost-effective when compared to liraglutide. Sitagliptin is the first agent of the DPP-4 inhibitor with other substances following soon after. The evaluation shows that the prevention of complications in patients with type 2 diabetes and cardiovascular disease (CVD) in the SGLT2 inhibitor group is more recommended, namely empaglifozin as the second line compared to sitagliptin.
A Literature Review: Effectiveness of NSAIDs in Osteoarthritis Patients Adrianto, Madyo; Anak Agung Pradnya Paramitha Vidiani; Puspitaningrum, Anisa Nova; Girsang, Valentina
Science and Community Pharmacy Journal Vol. 3 No. 2 (2024): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v3i2.582

Abstract

Pain, stiffness, swelling, and decreased joint function are some of the clinical signs of osteoarthritis, a disease that affects numerous anatomical and physiological aspects of joint tissue, cartilage degradation, bone remodeling, and osteophyte development. This literature review's objective is to ascertain the efficacy of NSAIDs in osteoarthritis by searching for journals from PubMed.. The method used was to search for articles through pubmed using the keywords "NSAID", "osteoarthritis", "Therapy" with a filter added for the last 5 years (2019-2024) obtained 103 articles. Then with the keywords "NSAID", "osteoarthritis", "therapy", "efficacy" obtained 71 articles. After analysis, there are 13 journals that can be include into inclusion requirement. NSAIDs preparations are particularly helpful for osteoarthritis therapy, both in knee and hip osteoarthritis. NSAIDs medications in a variety of dose forms, including oral, topical, spray, injection and plaster, are useful in relieving pain in osteoarthritis patients
Efektivitas Antibakteri Ekstrak Daun Glodokan Tiang (Polyalthia longifolia) Terhadap Cutibacterium acnes dan Staphylococcus epidermidis Girsang, Valentina; Nufus , Nunky; Saptawati , Tunik; Sa’adah , Anifatus; Wibowo, Anisa Devi Kharisma; Vidiani , Anak Agung Pradnya Paramitha
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.815

Abstract

Introduction: Polyalthia longifolia, commonly known as Glodokan tiang, is a plant typically found along roadsides, serving as shade and an ornamental feature in gardens. In addition to its aesthetic function, the leaves of this plant have been found to contain compounds with effective antibacterial activity. Natural ingredients with antibacterial properties, such as Polyalthia longifolia leaf extract, can be an alternative acne treatment due to their lower side effects than chemical drugs. Research Objective: This study aims to test the antibacterial activity of Polyalthia longifolia leaf extract in inhibiting the growth of Staphylococcus epidermidis and Cutibacterium acnes, which are significant causes of acne. Research Method: Polyalthia longifolia leaves were extracted using a maceration method with 70% ethanol as the solvent. The resulting extract was then tested for antibacterial activity using the disc diffusion method at 30%, 35%, 40%, 45%, and 50%. The bacteria used in the tests were Staphylococcus epidermidis and Cutibacterium acnes. Clindamycin was used as a positive control, and sterile water was used as a negative control. The data obtained from the tests were analyzed using the Kruskal-Wallis and post-hoc Games-Howell tests. Results: The study showed that Polyalthia longifolia leaf extract at various concentrations (30%, 35%, 40%, 45%, 50%) exhibited significant antibacterial activity against both bacteria tested. At a concentration of 50%, the extract demonstrated the most potent inhibitory effect on Cutibacterium acnes and Staphylococcus epidermidis, with inhibition zones reaching 15.82 mm and 15.74 mm, respectively. Conclusion: Polyalthia longifolia leaf extract shows significant antibacterial potential against Staphylococcus epidermidis and Cutibacterium acnes. The 50% extract concentration exhibited the most potent inhibitory effect, making it a promising candidate for natural acne treatment with minimal side effects.
Gambaran Kepatuhan Penderita Hipertensi Di Puskesmas Ngaliyan Kota Semarang Dengan Pendekatan Social Cognitive Theory (SCT) Gloria, Fransisca; Safrida, Safrida; Dahliyanti, Novita Dwi; Vidiani, Anak Agung Pradnya Paramitha; Suwarni, Sri
Jurnal Farmasi & Sains Indonesia Vol 8 No 1 (2025)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol8no1p257-263

Abstract

Based on the 2018 Riskesdas, the prevalence of hypertension in Indonesia was 34.1%, where Central Java reached 37.57%, and Semarang City ranked first at 19.56%. Hypertension is a major risk factor for cardiovascular disease that occurs when a person's blood pressure is 140/90 mmHg or more, also due to patient's non-compliance in taking medication. This study aims to determine the picture of compliance in patients with hypertension using the Social Cognitive Theory (SCT) approach. This observational study used a cross-sectional method with the Hill-Bone and SCT compliance questionnaires. This study was conducted at the outpatient pharmacy service of the Ngaliyan Health Center in Semarang City in the period March-May 2024 with a total of 145 respondents. The results obtained were that the level of compliance in taking medication for hypertension patients mostly had a moderate level of compliance of 100 respondents (69%), while respondents who had a low level of compliance were 30 respondents (21%) and those who had high compliance were 15 respondents (10%). The results of the SCT approach showed that most hypertension sufferers were in the high category with 56 respondents (47%), the moderate category with 68 respondents (47%), and the low category with 21 respondents (14%).
Analisis literasi kesehatan pasien diabetes melitus tipe 2 dengan terapi oral antidiabetes di puskesmas Surabaya Vidiani , Anak Agung Pradnya Paramitha; Puspitaningrum, Anisa Nova
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.413

Abstract

Introduction: Diabetes mellitus (DM) is a chronic disease requiring long-term therapy. Uncontrolled glucose levels can lead to micro and macrovascular complications as well as therapy failure. Medication adherence is a factor influencing the success of DM therapy. The aim of this study is to understand the adherence to oral antidiabetic drugs (OAD). Methods: This research employs a quantitative approach with a non-experimental cross-sectional design. The sample consists of all type 2 DM patients using OAD therapy at Surabaya Community Health Centers who meet the inclusion and exclusion criteria. Results and Conclusion: The health literacy level of Type 2 Diabetes Mellitus Referral Program patients who received Oral Anti-Diabetes therapy at the Surabaya Community Health Center in this study was 45% with high health literacy and 55% with low health literacy with a percentage of 55%. With the domains of patient attitudes towards health (72.50%), patient understanding of health information (57.50%), social support (22.50%), socio-economic considerations (75.00%), accessing health services (92.50%), 50%), communication with health workers (77.50%), pro-active (17.50%), and using health information (80.00%)
Co-Authors Adrianto, Madyo Amelia Lorensia Anisa Devi Kharisma Wibowo Anisa Nova Puspitaningrum Dahliyanti, Novita Dwi Fransisca Gloria Girsang, Valentina Gloria, Fransisca Lisa Aditama, Lisa Livania Indri Aswara Madyo Adrianto Nufus , Nunky Puspitaningrum , Anisa Nova Puspitaningrum, Anisa Nova Rustaman , Heri Safrida Safrida Sa’adah , Anifatus Sri Suwarni Tunik Saptawati Valentina Girsang Widiasari , Anggun