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All Journal Buletin Farmatera Best Journal (Biology Education, Sains and Technology) Jurnal Kedokteran Ibnu Nafis Jurnal Pengabdian Pada Masyarakat METHABDI Majalah Ilmiah METHODA Deli Medical and Health Science Journal Jurnal Kedokteran Methodist
Pasaribu, Sumihar
Universitas Methodist Indonesia
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PRO-INFLAMASI VERSUS ANTI-INFLAMASI SITOKIN: MITOS ATAU KENYATAAN Pasaribu, Sumihar M. R.
Majalah Ilmiah METHODA Vol. 14 No. 1 (2024): Majalah Ilmiah METHODA
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Inflammation is characterized by interactions between pro- and anti-inflammatory cytokines. Cytokines are generally classified in one or another category: interleukin-1 (IL-1), tumor necrosis factor (TNF), gamma-interferon (IFN-γ), IL-12, IL-18 and granulocyte-macrophage colony-stimulating factor, . classified as pro-inflammatory cytokines while IL-4, IL-10, IL-13, IFN-α and transforming growth factor-β are anti-inflammatory cytokines. In this review, it is demonstrated that this classification is too simplistic and provides many examples illustrating that certain cytokines can behave as both pro- and anti-inflammatory cytokines. It is true, the amount of cytokines, the nature of the target cells, the nature of the activation signal, the nature of the cytokines produced, the timing, the order of action of the cytokines and even the experimental model are parameters that greatly influence the properties of the cytokines.
PENYULUHAN PEMBERDAYAAN MASYARAKAT DALAM PENCEGAHAN STUNTING DESA AJIJULU, KABUPATEN KARO Siahaan, Jekson Martiar; Silitonga, Hendrika Adriana; Lim, Hadyanto; Pasaribu, Sumihar M. R.; Tarigan, Menang Bastanta; Jamnasi, Juli; Sinatra, Jadeny; Simanjuntak, Salomo Garda Utama; Sembiring, Budi Darmanta; Pakpahan, Edwin Anto; Hutagalung, Sanggam B.; Sinurat, Suryati; Br. T. Tambun, Gita Sradha; Hakim, Enggrek Pelita
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 3 No 1 (2023): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methabdi.Vol3No1.pp11-14

Abstract

Community Service (PKM) conducted by the Faculty of Medicine at the Indonesian Methodist University provides counseling on stunting prevention. PKM was held on April 14-16 2023 in Ajijulu Village, Tigapanah District, Karo Regency, North Sumatra. Lectures, discussions and motivations are used as orientation methods. Question and answer discussions were held with the aim of gaining insight, understanding and solutions to solve the problems and limitations faced by the local community. The results of the PKM suggestions and research are very effective, considering that there are still many people who are ignorant of stunting prevention. This counseling increases public awareness about stunting prevention. Residents of Ajijulu must be aware and know the importance of preventing stunting, starting from the time of pregnancy and the first 1000 days of life for toddlers.
HUBUNGAN JENIS KELAMIN, MASA KERJA, DAN POSISI KERJA DENGAN GANGGUAN OTOT RANGKA AKIBAT KERJA PADA PETANI DI KABUPATEN DELI SERDANG TAHUN 2022: THE RELATIONSHIP OF GENDER, LENGTH OF WORK, AND WORK POSITION WITH WORK-DUE TO SKELETAL MUSCLE DISORDERS IN FARMERS IN DELI SERDANG DISTRICT YEAR 2022 Pasaribu, Sumihar; Tanjung, Lina Febriani; Girsang, Rostiodertina; Alwi, Fahrizal
Jurnal Kedokteran Ibnu Nafis Vol. 14 No. 1 (2025): Juni 2025
Publisher : Fakultas Kedokteran Universitas Islam Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/jkin.v14i1.822

Abstract

Gangguan otot rangka merupakan salah satu masalah kesehatan yang sering dialami pekerja di sektor pertanian akibat postur kerja yang tidak ergonomis, masa kerja panjang, dan beban kerja fisik yang berat. Penelitian ini bertujuan untuk menganalisis hubungan antara jenis kelamin, masa kerja, dan posisi kerja terhadap gangguan muskuloskeletal pada petani di Kabupaten Deli Serdang. Penelitian menggunakan desain cross-sectional dengan 30 responden yang dipilih melalui metode consecutive sampling. Data dikumpulkan menggunakan kuesioner, penilaian Rapid Entire Body Assessment (REBA) untuk posisi kerja, dan Nordic Body Map (NBM) untuk keluhan gangguan otot rangka. Analisis bivariat menunjukkan hubungan signifikan antara jenis kelamin (p = 0,045; PR = 0,167), masa kerja (p = 0,007; PR = 13,500), dan posisi kerja (p = 0,001; PR = 22,667) terhadap gangguan otot rangka. Posisi kerja yang tidak ergonomis merupakan faktor risiko utama. Temuan ini menegaskan pentingnya intervensi ergonomis, edukasi, dan pelatihan untuk mengurangi prevalensi gangguan muskuloskeletal pada petani.
PENYULUHAN KONTROL HIPERTENSI DAN DIABETES SEJAK DINI KEPADA JEMAAT GEREJA HKBP GEDUNG JOHOR RESORT, KECAMATAN MEDAN JOHOR Anto, Endy Juli; Hutasoit, Eka Samuel P.; Siahaan, Jekson M.; Rimbun, Surjadi; Manullang, Frengky S.; Tiji, Widjaya Taufik; Tambunan, Ronald Tunggul Hotmarojahan; Lim, Hadyanto; Pasaribu, Sumihar Maurist Rantos; Tarigan, Menang Bastanta; Jamnasi, Juli; Sinatra, Jadeny; Silitonga, Hendrika Adriana
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 3 No 2 (2023): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methabdi.Vol3No2.pp128-132

Abstract

Community Service (PKM) in the form of health education conducted by lecturers at the Faculty of Medicine, Indonesian Methodist University provides outreach about the benefits of controlling hypertension and diabetes mellitus from an early age. PKM was held on August 5 2023 at the HKBP church, Medan Johor District, North Sumatra. Lectures, question and answer discussions and motivation are used as orientation methods. A question and answer discussion was held with the aim of gaining insight and understanding to avoid complications from hypertension and DM. The results of PKM's socialization and work are very effective considering that there are still many people who have not received information about the benefits of vaccination through the basic immunization program. This education makes people more aware of the importance of routine control of health services. The HKBP church community must be aware and know the importance of early control in avoiding complications.
PENYULUHAN PENCEGAHAN STUNTING PADA ANAK DI SD NEGERI 060919 Tarigan, Juliyanti; Syahrir, Lesmana; Tiji, Wijaya Taufik; Simangunsong, Batara; Pasaribu, Sumihar M.R.; Gea, Melfan J.; Harianja, Ester G.; Tampubolon, Gelberd V.M.; Simalango, Penina T.; Ginting, Lucky A.B.; Sibuea, Charina T.Y.; Pangaribuan, Megaria Evhiphanias; Simanullang, Yolanda K.H.R.; Ginting, Mischkel A.; Meha, Panahian M.
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 3 No 2 (2023): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methabdi.Vol3No2.pp208-211

Abstract

Stunting is a situation where a child's height is stunted compared to the height of children his age. In Indonesia, stunting is a problem in the health sector that is still high. This condition occurs because children are malnourished for a long time with signs of failure in the child's growth and development (growth faltering) which starts from pregnancy until the child is 2 years old. This is the formulation of our problem in holding outreach activities on the topic of Stunting at SD Negeri 060919, Kec. Medan Sunggal, Medan city. This article was created with the aim of providing education and information regarding stunting prevention. Thus, this activity is very useful in providing information about how to prevent and reduce the incidence of stunting. It is hoped that this activity will be carried out at SD Negeri 060919, Kec. Medan Sunggal, Medan City to pay more attention to the nutritional intake of mothers and children, so that the incidence of stunting in Indonesia is reduced.
Literature Review: Relationship Between Rubber Factory Pollution Exposure and Reactive Oxygen Species (ROS) Levels in Workers Pasaribu, Sumihar MR; Purba, Amril; Perangin-angin, Guntur; Siahaan, Jekson Martiar
Buletin Farmatera Vol 10, No 3 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i3.25610

Abstract

Abstract: Working in rubber factories exposes personnel to a cocktail of airborne contaminants—hydrogen sulfide, organic solvents, and fine dust—that jeopardise health over the long term. A key pathological response to such pollution is the upsurge in reactive oxygen species (ROS), which drives oxidative stress and underlies injury to cells, tissues, and organ systems. The present review compiles biomarker and mechanistic data showing how encounters with factory fumes correlate with elevated ROS levels in exposed workers. Cross-sectional surveys and laboratory experiments consistently report raised indicators such as malondialdehyde (MDA) and 8-hydroxy-2-deoxyguanosine (8-OHdG), establishing a robust link between airborne toxins and molecular damage. Genetic variants that weaken antioxidant enzymes further shape individual risk, reminding us that not every worker faces the same burden even under identical exposure conditions. Consequences typically affect the respiratory tract, heart, and metabolic pathways, reinforcing calls for stronger engineering controls, personal monitoring, and health surveillance in the plant. Early trials of antioxidant supplements show promise for damping ROS pathways, yet the field still lacks evidence-based protocols that tailor interventions to sources and dosages of pollution. By clarifying these oxidative processes, the review aims to guide regulators and industry managers in crafting rules that truly protect workers' lives and livelihoods
PRO-INFLAMASI VERSUS ANTI-INFLAMASI SITOKIN: MITOS ATAU KENYATAAN Pasaribu, Sumihar M. R.
Majalah Ilmiah METHODA Vol. 14 No. 1 (2024): Majalah Ilmiah METHODA
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methoda.Vol14No1.pp120-131

Abstract

Inflammation is characterized by interactions between pro- and anti-inflammatory cytokines. Cytokines are generally classified in one or another category: interleukin-1 (IL-1), tumor necrosis factor (TNF), gamma-interferon (IFN-γ), IL-12, IL-18 and granulocyte-macrophage colony-stimulating factor, . classified as pro-inflammatory cytokines while IL-4, IL-10, IL-13, IFN-α and transforming growth factor-β are anti-inflammatory cytokines. In this review, it is demonstrated that this classification is too simplistic and provides many examples illustrating that certain cytokines can behave as both pro- and anti-inflammatory cytokines. It is true, the amount of cytokines, the nature of the target cells, the nature of the activation signal, the nature of the cytokines produced, the timing, the order of action of the cytokines and even the experimental model are parameters that greatly influence the properties of the cytokines.
Pengaruh Kombinasi Mindfulnes Breathing And Guided Imagery Terhadap Penurunan Kecemasan Emosi Negatif Pada Ibu Post Sectio Caesarea Purba, Tetty Junita; Ariani, Peny; Pasaribu, Sumihar; Sitorus, Friska Ernita; Sembiring, Alprindo
BEST Journal (Biology Education, Sains and Technology) Vol 8, No 2 (2025): September 2025
Publisher : Program Studi Pendidikan Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/best.v8i2.12206

Abstract

Abstrak- Sectio caesarea merupakan prosedur bedah mayor yang sering menimbulkan dampak psikologis berupa kecemasan dan emosi negatif pada ibu postpartum. Kondisi ini dapat mengganggu pemulihan, menghambat ikatan ibu dan bayi, serta meningkatkan risiko depresi postpartum. Intervensi non-farmakologis seperti mindfulness breathing dan guided imagery dipandang efektif dalam menurunkan kecemasan dan meningkatkan regulasi emosi, namun penelitian mengenai kombinasi keduanya masih terbatas. Penelitian ini bertujuan untuk menganalisis pengaruh kombinasi mindfulness breathing dan guided imagery terhadap penurunan kecemasan dan emosi negatif pada ibu post-sectio caesarea. Penelitian menggunakan desain pre–post test without control group dengan jumlah responden sebanyak 49 orang ibu post-sectio caesarea yang dipilih melalui teknik purposive sampling. Instrumen penelitian meliputi kuesioner Hospital Anxiety and Depression Scale-Anxiety (HADS-A) untuk mengukur kecemasan dan Positive and Negative Affect Schedule-Negative Affect (PANAS-NA) untuk mengukur emosi negatif. Data dianalisis menggunakan uji normalitas Shapiro-Wilk dan uji paired t-test.Rata-rata skor kecemasan menurun dari 11,18 (SD = 3,68) menjadi 6,90 (SD = 4,34), sedangkan rata-rata skor emosi negatif menurun dari 29,96 (SD = 5,55) menjadi 23,73 (SD = 5,88). Uji paired t-test menunjukkan adanya perbedaan signifikan pada kecemasan (t(48) = 7,95; p < 0,001) dan emosi negatif (t(48) = 8,42; p < 0,001). Kombinasi mindfulness breathing dan guided imagery terbukti efektif menurunkan kecemasan dan emosi negatif pada ibu post-sectio caesarea. Intervensi ini sederhana, mudah diterapkan, minim efek samping, dan dapat diintegrasikan ke dalam praktik keperawatan maternitas sebagai upaya mendukung pemulihan psikologis ibu postpartum
PENYULUHAN PEMBERDAYAAN MASYARAKAT DALAM PENCEGAHAN STUNTING DESA AJIJULU, KABUPATEN KARO Siahaan, Jekson Martiar; Silitonga, Hendrika Adriana; Lim, Hadyanto; Pasaribu, Sumihar M. R.; Tarigan, Menang Bastanta; Jamnasi, Juli; Sinatra, Jadeny; Simanjuntak, Salomo Garda Utama; Sembiring, Budi Darmanta; Pakpahan, Edwin Anto; Hutagalung, Sanggam B.; Sinurat, Suryati; Br. T. Tambun, Gita Sradha; Hakim, Enggrek Pelita
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 3 No 1 (2023): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methabdi.Vol3No1.pp11-14

Abstract

Community Service (PKM) conducted by the Faculty of Medicine at the Indonesian Methodist University provides counseling on stunting prevention. PKM was held on April 14-16 2023 in Ajijulu Village, Tigapanah District, Karo Regency, North Sumatra. Lectures, discussions and motivations are used as orientation methods. Question and answer discussions were held with the aim of gaining insight, understanding and solutions to solve the problems and limitations faced by the local community. The results of the PKM suggestions and research are very effective, considering that there are still many people who are ignorant of stunting prevention. This counseling increases public awareness about stunting prevention. Residents of Ajijulu must be aware and know the importance of preventing stunting, starting from the time of pregnancy and the first 1000 days of life for toddlers.
PENYULUHAN KONTROL HIPERTENSI DAN DIABETES SEJAK DINI KEPADA JEMAAT GEREJA HKBP GEDUNG JOHOR RESORT, KECAMATAN MEDAN JOHOR Anto, Endy Juli; Hutasoit, Eka Samuel P.; Siahaan, Jekson M.; Rimbun, Surjadi; Manullang, Frengky S.; Tiji, Widjaya Taufik; Tambunan, Ronald Tunggul Hotmarojahan; Lim, Hadyanto; Pasaribu, Sumihar Maurist Rantos; Tarigan, Menang Bastanta; Jamnasi, Juli; Sinatra, Jadeny; Silitonga, Hendrika Adriana
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 3 No 2 (2023): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methabdi.Vol3No2.pp128-132

Abstract

Community Service (PKM) in the form of health education conducted by lecturers at the Faculty of Medicine, Indonesian Methodist University provides outreach about the benefits of controlling hypertension and diabetes mellitus from an early age. PKM was held on August 5 2023 at the HKBP church, Medan Johor District, North Sumatra. Lectures, question and answer discussions and motivation are used as orientation methods. A question and answer discussion was held with the aim of gaining insight and understanding to avoid complications from hypertension and DM. The results of PKM's socialization and work are very effective considering that there are still many people who have not received information about the benefits of vaccination through the basic immunization program. This education makes people more aware of the importance of routine control of health services. The HKBP church community must be aware and know the importance of early control in avoiding complications.
Co-Authors Alprindo Sembiring Meliala Alwi, Fahrizal Ariani, Peny Br. Siahaan, Thresia Deswinta Br. T. Tambun, Gita Sradha Endy Juli Anto Gea, Melfan J. Ginting, Lucky A.B. Ginting, Mischkel A. Girsang, Rostiodertina Hadyanto Lim Hakim, Enggrek Pelita Harianja, Ester G. Hutagalung, Sanggam B. Hutasoit, Eka Samuel P. Juli Jamnasi Lesmana Syahrir, Lesmana Manullang, Frengky S. Marpaung, Angelina Patricia Br Meha, Panahian M. Pakpahan, Edwin Anto Pangaribuan, Megaria Evhiphanias Perangin-angin, Guntur Purba, Amril Purba, Tetty Junita Rimbun, Surjadi Sembiring, Budi Darmanta Siahaan, Jekson Martiar Sibuea, Charina T.Y. Silitonga, Hendrika Adriana Simalango, Penina T. Simangunsong, Batara Simanjuntak, Salomo Garda Utama Simanullang, Yolanda K.H.R. Sinatra, Jadeny Sinurat, Suryati Sitompul, Donald F Sitorus, Friska Ernita Suryati Sinurat Tambunan, Ronald Tunggul Hotmarojahan Tampubolon, Gelberd V.M. Tanjung, Lina Febriani Tarigan, Juliyanti Tarigan, Menang Bastanta Tiji, Widjaya Taufik Tiji, Wijaya Taufik Wijaya, Moses