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Faktor Yang Mempengaruhi Kejadian Skabies Pada Santri Di Pondok Pesantren Hidayatullah Tanjung Morawa Br Ginting, Heni Sry Wahyuni; Faried Lubis, Taufik Akbar; Nurfadly, Nurfadly; Syafrin Lubis, Riri Arisanty
Buletin Farmatera Vol 10, No 2 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i2.24364

Abstract

Abstract: Scabies is a skin disease caused by infestation and sensitization to the hominis variant Sarcoptes scabei mite and its products.According to the Ministry of Health of the Republic of Indonesia, the prevalence of scabies in 2020 was 3.9%-6%.This states that Indonesia is still not free from scabies and is one of the infectious skin disease problems in Indonesia. The factors that cause the incidence of scabies to increase are high humidity, low sanitation, environmental density, poor personal hygiene, knowledge and attitudes and behaviors that are not supportive for a healthy lifestyle. The prevalence of scabies in Islamic boarding schools is still fairly high based on the results of the research conducted.This study aims to find out Factors Influencing the Occurrence of Scabies To students at Hidayatullah Islamic Boarding School Tanjung Morawa. cross seictional Observational analytics using a cross sectional design. Data were obtained through filling out questionnaires and physical examination of 94 samples then analyzed using univariate, bivariate analysis with the chi-square method and multivariate analysis will be carried out using multiple logistic regression tests to see the most dominant risk factors for Sarcoptes scabeii var infection. hominis. Data analysis using Chi Square showed that there was a relationship between Age and Personal hygiene Logistic regression analysis showed that the personal hygiene variable was the most dominant variable related to the event.
Antibacterial Activity of Mangrove Leaves Extract (Rhizopora Apiculata) Against Salmonella typhi Growth Nurfadly, Nurfadly; Harahap, Sevani Ayu; Roslina, Ance; Sarirah, Munauwarus
Majalah Kedokteran Bandung Vol 57, No 3 (2025)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v57.4092

Abstract

Mangrove leaves (Rhizopora apiculata) contain antibacterial chemical compounds with antibacterial properties against various pathogens. Salmonella typhi, the causative agent of thyphoid fever, triggers a systemic infectious disease that can lead to complications and deaths if not treated properly.  This study aimed to screen the phytochemical content of R. apiculata leaf extract, evaluate its antibacterial activity against S. typhi, and determine the optimal inhibitory concentration. Leaves were collected from the Sicanang mangrove forest in Belawan, North Sumatra, Indonesia, and extracted using the maceration method with 96% ethanol.  Antibacterial effectiveness was assessed using disc diffusion method by measuring the zone of inhibition after exposure to mangrove leaf extract at concentrations of 40%, 60%, 80%, and 100%, with chloramphenicol as a positive control, to determine the most effective concentration for inhibiting the growth of Salmonella typhi. The results of the study showed that there were differences in inhibition zones in each group. Mangrove leaves extract at a concentration of 100% is the most effective in inhibiting the growth of Salmonella typhi compared to 80%, 60%, and 40% concentrations.
Effect of Ketapang Leaf Extract on HDL Levels of Rattus norvegicus Induced by High-fat Foods Nurfadly, Nurfadly; Fajar, Muhammad; Thristy, Isra; Yenita, Yenita
Global Medical & Health Communication (GMHC) Vol 12, No 3 (2024)
Publisher : Universitas Islam Bandung

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Abstract

High-density lipoprotein (HDL) functions to transport cholesterol from the blood vessel endothelium to the liver and excreted through the digestive tract so that it does not cause dyslipidemia, which is a risk factor for cardiovascular disease. Current treatment for dyslipidemia uses long-term statin drugs, which can cause various side effects, so herbal alternatives such as ketapang leaves (Terminalia catappa L.), which contain flavonoids and have the effect of increasing HDL levels, needed to be evaluated to achieve that reason. This study aims to evaluate whether ketapang leaf extract has an effect on increasing blood HDL levels. This research used experimental animals with a pretest and a posttest with a control group design. It was conducted at the Biochemistry Laboratory and Laboratory Animal Management Unit, Faculty of Medicine, Universitas Muhammadiyah Sumatera Utara, Medan, from September to December 2023. This study used Wistar strain male white rats (Rattus norvegicus) that were induced on a high-fat diet, divided into five groups: negative control, positive control (given simvastatin), treatment 1 (given 21 mg/kgBW ketapang leaf extract), treatment 2 (given 42 mg/kgBW ketapang leaf extract) and treatment 3 (given 84 mg/kgBW ketapang leaf extract). The study results showed a significant difference (p<0.05) in the average HDL levels before and after treatment in the positive control, treatment 2, and therapy three groups. Thus, the study concluded that ketapang leaf extract affected increasing HDL levels of male white rats (Rattus norvegicus). DOI: https://doi.org/10.29313/gmhc.v12i3.14070