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All Journal Majalah Kedokteran Bandung KUMPULAN JURNAL DOSEN UNIVERSITAS MUHAMMADIYAH SUMATERA UTARA Global Medical and Health Communication JURNAL IBNU SINA BIOMEDIKA Buletin Farmatera Hasil Pengabdian Kepada Masyarakat JURNAL ILMIAH MAKSITEK JURNAL ILMIAH SIMANTEK JURNAL ILMIAH KOHESI Muhammadiyah Medical Journal Jurnal Pandu Husada JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Jurnal Implementa Husada (JIH)
Nurfadly, Nurfadly
Universitas Muhammadiyah Sumatera Utara
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Faktor Yang Mempengaruhi Kejadian Skabies Pada Santri Di Pondok Pesantren Hidayatullah Tanjung Morawa Br Ginting, Heni Sry Wahyuni; Faried Lubis, Taufik Akbar; Nurfadly, Nurfadly; Syafrin Lubis, Riri Arisanty
Buletin Farmatera Vol 10, No 2 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i2.24364

Abstract

Abstract: Scabies is a skin disease caused by infestation and sensitization to the hominis variant Sarcoptes scabei mite and its products.According to the Ministry of Health of the Republic of Indonesia, the prevalence of scabies in 2020 was 3.9%-6%.This states that Indonesia is still not free from scabies and is one of the infectious skin disease problems in Indonesia. The factors that cause the incidence of scabies to increase are high humidity, low sanitation, environmental density, poor personal hygiene, knowledge and attitudes and behaviors that are not supportive for a healthy lifestyle. The prevalence of scabies in Islamic boarding schools is still fairly high based on the results of the research conducted.This study aims to find out Factors Influencing the Occurrence of Scabies To students at Hidayatullah Islamic Boarding School Tanjung Morawa. cross seictional Observational analytics using a cross sectional design. Data were obtained through filling out questionnaires and physical examination of 94 samples then analyzed using univariate, bivariate analysis with the chi-square method and multivariate analysis will be carried out using multiple logistic regression tests to see the most dominant risk factors for Sarcoptes scabeii var infection. hominis. Data analysis using Chi Square showed that there was a relationship between Age and Personal hygiene Logistic regression analysis showed that the personal hygiene variable was the most dominant variable related to the event.
Antibacterial Activity of Mangrove Leaves Extract (Rhizopora Apiculata) Against Salmonella typhi Growth Nurfadly, Nurfadly; Harahap, Sevani Ayu; Roslina, Ance; Sarirah, Munauwarus
Majalah Kedokteran Bandung Vol 57, No 3 (2025)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v57.4092

Abstract

Mangrove leaves (Rhizopora apiculata) contain antibacterial chemical compounds with antibacterial properties against various pathogens. Salmonella typhi, the causative agent of thyphoid fever, triggers a systemic infectious disease that can lead to complications and deaths if not treated properly.  This study aimed to screen the phytochemical content of R. apiculata leaf extract, evaluate its antibacterial activity against S. typhi, and determine the optimal inhibitory concentration. Leaves were collected from the Sicanang mangrove forest in Belawan, North Sumatra, Indonesia, and extracted using the maceration method with 96% ethanol.  Antibacterial effectiveness was assessed using disc diffusion method by measuring the zone of inhibition after exposure to mangrove leaf extract at concentrations of 40%, 60%, 80%, and 100%, with chloramphenicol as a positive control, to determine the most effective concentration for inhibiting the growth of Salmonella typhi. The results of the study showed that there were differences in inhibition zones in each group. Mangrove leaves extract at a concentration of 100% is the most effective in inhibiting the growth of Salmonella typhi compared to 80%, 60%, and 40% concentrations.
Effect of Ketapang Leaf Extract on HDL Levels of Rattus norvegicus Induced by High-fat Foods Nurfadly, Nurfadly; Fajar, Muhammad; Thristy, Isra; Yenita, Yenita
Global Medical & Health Communication (GMHC) Vol 12, No 3 (2024)
Publisher : Universitas Islam Bandung

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Abstract

High-density lipoprotein (HDL) functions to transport cholesterol from the blood vessel endothelium to the liver and excreted through the digestive tract so that it does not cause dyslipidemia, which is a risk factor for cardiovascular disease. Current treatment for dyslipidemia uses long-term statin drugs, which can cause various side effects, so herbal alternatives such as ketapang leaves (Terminalia catappa L.), which contain flavonoids and have the effect of increasing HDL levels, needed to be evaluated to achieve that reason. This study aims to evaluate whether ketapang leaf extract has an effect on increasing blood HDL levels. This research used experimental animals with a pretest and a posttest with a control group design. It was conducted at the Biochemistry Laboratory and Laboratory Animal Management Unit, Faculty of Medicine, Universitas Muhammadiyah Sumatera Utara, Medan, from September to December 2023. This study used Wistar strain male white rats (Rattus norvegicus) that were induced on a high-fat diet, divided into five groups: negative control, positive control (given simvastatin), treatment 1 (given 21 mg/kgBW ketapang leaf extract), treatment 2 (given 42 mg/kgBW ketapang leaf extract) and treatment 3 (given 84 mg/kgBW ketapang leaf extract). The study results showed a significant difference (p<0.05) in the average HDL levels before and after treatment in the positive control, treatment 2, and therapy three groups. Thus, the study concluded that ketapang leaf extract affected increasing HDL levels of male white rats (Rattus norvegicus). DOI: https://doi.org/10.29313/gmhc.v12i3.14070
The Effect of Mangrove Leaf Extract (Rhizophora apiculata) on Blood Cholesterol Levels of White Mice (Mus musculus) Induced by Egg Yolk Yuliansyah, Putri Ridha; Nurfadly, Nurfadly; Purwiningsih, Emni; Lubis, Humairah Medina Liza
Buletin Farmatera Vol 12, No 1 (2027)
Publisher : Universitas Muhammadiyah Sumatera Utara

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Abstract

Abstract: Cholesterol is the primary sterol in the human body, produced by the liver. While essential, excessive cholesterol can accumulate as plaques in blood vessels. Rhizophora apiculata contains secondary metabolites such as flavonoids, tannins, alkaloids, saponins, and terpenoids, which are believed to influence HDL and LDL levels. This study aims to investigate the effect of Rhizophora apiculata leaf extract on HDL and LDL levels in male white mice (Mus musculus) induced with egg yolk. This true experimental study applied a post-test with a control group design. A total of 36 white mice were divided into six groups, consisting of negative, positive, and treatment groups. Mice were acclimatised for one week, induced with quail egg yolk, and administered Rhizophora apiculata leaf extract for 30 days. Blood HDL and LDL levels were then measured and analysed using One-way ANOVA. The Shapiro-Wilk and Levene’s tests showed p-values 0.05. The One-way ANOVA indicated significant differences in HDL and LDL levels between groups (p0.05). LSD post hoc tests showed treatment groups P1, P2, and P3 differed significantly from the negative control. Rhizophora apiculata leaf extract affects HDL and LDL levels in male white mice induced by egg yolk.
Hubungan Tingkat Pengetahuan dengan Tindakan Pencegahan Toxoplasmosis Pada Pemelihara Kucing Di Kecamatan Medan Kota Izzatus Hilmi. Z; Nurfadly Nurfadly; Elman Boy; Irfan Darfika
JURNAL IMPLEMENTA HUSADA Vol 4, No 1 (2023)
Publisher : UMSU

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/jih.v4i1.13554

Abstract

Toxoplasmosis merupakan penyakit zoonosis yang disebabkan oleh parasit Toxoplasma gondi. Prevalensi toxoplasmosis di Indonesia hingga tahun 2017 yang pernah dilaporkan adalah 43-88% kasus. Manusia dapat tertular melalui Feses kucing yang mengandung ookista Toxoplasma gondii, sehingga pemelihara kucing membutuhkan pengetahuan tentang toxoplasmosis dan pencegahan penularan toksoplasmosis. Tingkat pengetahuan pemelihara kucing dapat menjadi suatu aspek dalam tindakan pencegahan toxoplasmosis. Sehingga, peneliti tertarik untuk menghubungkan antara tingkat pengetahuan dengan tindakan pencegahan toxoplasmosis pada pemelihara kucing di kecamatan Medan kota. Metode penelitian : Penelitian ini  menggunakan metode observasional analitik dengan design cross sectional dengan menggunakan kuesioner sebagai instrumen penelitian. Pengambilan sampel menggunakan teknik purposive sampling. Hasil : Subjek penelitian berjumlah 103 responden. Subjek yang memiliki tingkat pengetahuan baik berjumlah 43,7%, subjek yang memiliki tindakan pencegahan baik berjumlah 40,8%. Uji korelasi antara tingkat pengetahuan dan tingkat pencegahan didapatkan nilai sig. 0,05 nilai correlation coefficient (r) 0.554. Kesimpulan : Terdapat hubungan positif dan searah antara tingkat pengetahuan dengan tindakan pencegahan toxoplasmosis pada pemelihara kucing di kecamatan Medan Kota.
The Role of Cherry Coffee Ethanol Extract in Repairing Liver Damage in Type 2 Diabetic Rats Tengku Soraya Putri; Nurfadly Nurfadly; Humairah Medina Liza Lubis
JURNAL IMPLEMENTA HUSADA Vol 7, No 1 (2026)
Publisher : UMSU

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/jih.v7i1.25430

Abstract

Abstract:Background. Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by chronic hyperglycemia due to insulin resistance and pancreatic β-cell dysfunction. Chronic hyperglycemia triggers oxidative stress and increases inflammation, thereby contributing to liver damage. The potential of coffee cherry ethanol extract as an antioxidant and anti-inflammatory agent could serve as a therapeutic option for improving liver damage. Objective. This study aims to evaluate the effects of coffee cherry ethanol extract on liver histopathology in a T2DM mouse model. Methods. This study used 28 male Wistar rats, divided into 7 groups with 4 rats in each group, administered coffee cherry ethanol extract at doses of 100 mg/kg body weight and 200 mg/kg body weight/day/oral. Results. The results showed that administration of coffee cherry ethanol extract improved hepatocyte structure, reduced inflammatory infiltration, and decreased fat accumulation in liver tissue compared to the untreated DMT2 group (p0.05). Conclusion. Coffee cherry ethanol extract has potential as an adjunct therapy to slow the progression of DMT2 complications in the liver. Further studies are needed to confirm its efficacy, mechanism of action, and long-term effects in humans. Keywords: ethanol extract, liver histopathology, oxidative stress, type 2 diabetes mellitus. 
Co-Authors ALYA LAILATU ASSZIVA Amelia Eka Damayanty Ance Roslina Andini, Leni Br Ginting, Heni Sry Wahyuni Ceri Permata Ayuni ELMAN BOY Faried Lubis, Taufik Akbar Harahap, Sevani Ayu Humairah Medina Liza Lubis Iqrina Widia Zahara Irfan Darfika Isra Thristy Izzatus Hilmi. Z MIFTAH KHOIRIAH Muhammad Fajar Muhammad Jabbar Rahman Tapiheru MURLINA, NELLI Nasution, Aisyah Khoiriyah Pudiyanti, Pinta Purwiningsih, Emni Purwoningsih, Emni R. MUHAMMAD ZIKRI PRANOTO Ramadhani, Muhammad RIDO RAIS HUTABARAT Robitah Asfur SAID MUNAZAR RAHMAT Sarirah, Munauwarus Siregar, Nur Fitriani Syafrin Lubis, Riri Arisanty Tengku Soraya Putri Yenita . Yenita Yenita Yulfi, Hemma Yuliansyah, Putri Ridha Zahara, Iqrina Widia Zahir Husni Lubis ZIMLY KHATIF VALDIVIA RITONGA