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All Journal JBIO: jurnal biosains (the journal of biosciences) Jurnal Kesehatan Tambusai Journal of Experimental and Clinical Pharmacy (JECP) Proceeding of International Conference Health, Science And Technology (ICOHETECH) Indonesian Research Journal on Education Prosiding Seminar Informasi Kesehatan Nasional International Journal of Health, Engineering and Technology Jurnal Pengabdian Masyarakat dan Riset Pendidikan Aksi Nyata : Jurnal Pengabdian Sosial dan Kemanusiaan
Rohmana, Vivin Marwiyati
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Phytochemical Screening of Ater Bamboo Shoot Extract (Gigantochloa atter Kurz) with Different Solvents and Their Effect on Antioxidant Activity Using the DPPH Method Tiara Dhea Febryana; Septian Maulid Wicahco; Vivin Marwiyati Rohmana
International Journal of Health Engineering and Technology Vol. 4 No. 3 (2025): IJHET SEPTEMBER 2025
Publisher : CV. AFDIFAL MAJU BERKAH

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Abstract

An imbalance of free radicals in the body can cause a health condition known as oxidative stress. Oxidative stress is a condition in which free radicals and antioxidants in the body are out of balance. Oxidative stress can be overcome with natural antioxidants. This study aims to determine the antioxidant activity indicated by the IC50 value of the extract of bamboo ater shoots (Gigantochloa atter Kurz) extracted with different solvent polarities. The extraction process was carried out by the maceration method using 96% alcohol solvent, n-Hexane, and ethyl acetate. Each extract was then subjected to phytochemical screening tests, including flavonoids, steroids, alkaloids, tannins, saponins, and terpenoids. Analysis of antioxidant activity in this study was carried out using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. The results of phytochemical screening showed significant differences among each solvent, where the 96% alcohol solvent showed the most complete phytochemical screening results. Based on the results of the study, it can be concluded that bamboo ater shoots have antioxidant activity, and solvent polarities affect the IC50 value shown. The 96% alcohol extract of bamboo ater shoots has antioxidant activity with an IC50 value of 39.22 µg/mL, the extract of bamboo ater shoots with ethyl acetate solvent is 56.19 µg/mL, and the extract of bamboo ater shoots with n-Hexane solvent is 69.77 µg/mL.
Antioxidant Activity Test of Extract And Fractions of Red Guava (Psidium guajava L.) Peel and Fruit Monica; Rohmana, Vivin Marwiyati; Pratama, Kharisma Jayak
JURNAL BIOSAINS Vol. 11 No. 2 (2025): JURNAL BIOSAINS
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jbio.v11i2.68054

Abstract

Red guava (Psidium guajava L.) contains natural antioxidants that help neutralize free radicals originating from radiation, pollution, and harmful chemicals. This study aimed to identify secondary metabolites and determine the IC₅₀ values of ethanol extract and various fractions of red guava peel and fruit. Four solvents were used ethanol extract, ethyl acetate fraction, n-hexane fraction, and water fraction. Each sample was tested at concentrations of 20, 40, 60, 80, and 100 ppm. Vitamin C, at concentrations of 2, 4, 6, 8 and 10 ppm, served as a positive control. Antioxidant activity was evaluated using the DPPH method with a UV-Vis spectrophotometer at a wavelength of 516 nm and an incubation time of 30 minutes. Phytochemical screening showed that all extracts contained alkaloids, flavonoids, and tannins. The IC₅₀ values obtained were: ethanol extract peel 62,4719 ppm, ethanol extract fruit 44,0035 ppm, ethyl acetate fraction peel 56,7955 ppm, ethyl acetate fraction fruit 46,4394 ppm, n-hexane fraction peel 113,9311 ppm, n-hexane fraction fruit 114,4767 ppm, water fraction peel 104,0284 ppm, and water fraction fruit 76,5801 ppm.
ANALISIS Gap PENGARUH PELAYANAN INFORMASI OBAT TERHADAP KEPUASAN PASIEN RAWAT JALAN DI INSTALASI FARMASI RUMAH SAKIT PKU MUHAMMADIYAH SURAKARTA Rohmana, Vivin Marwiyati; Artini, Kusumaningtyas Siwi; A, Ferlinda Ayu
Prosiding Seminar Informasi Kesehatan Nasional 2024: SIKesNas 2024
Publisher : Fakultas Ilmu Kesehatan Universitas Duta Bangsa Surakarta

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Abstract

Studi ini bertujuan untuk mengetahui tingkat kesesuaian antara kinerja tenaga farmasi dengan harapan pasien rawat jalan di Instalasi Farmasi Rumah Sakit PKU Muhammadiyah Surakarta. Untuk mengetahui pengaruh kualitas pelayanan terhadap kepuasan pasien rawat jalan di instalasi farmasi rumah sakit PKU Muhammadiyah Surakarta. Penelitian ini dilakukan dengan menggunakan kuesioner yang diberikan pada 333 konsumen dengan metode purposive sampling di Instalasi Farmasi Rumah Sakit PKU Muhammadiyah Surakarta. Data dari korelasi antara variabel bebas (jenis informasi obat, sikap tenaga farmasi, kinerja tenaga farmasi, kemampuan berkomunikasi tenaga farmasi dan lama waktu pelayanan informasi obat) dengan variabel tergantung (kepuasan pasien) dianalisis dengan analisis regresi linier sederhana, analisis regresi berganda dan analisis Gap. Hasil penelitian menunjukkan bahwa presentase kepuasan pasien rawat jalan di Instalasi Farmasi Rumah Sakit PKU Muhammadiyah Surakarta faktor jenis informasi obat, sikap dan kinerja tenaga farmasi, kemampuan berkomunikasi tenaga farmasi dan lama waktu pelayanan informasi obat secara berurutan sebagai berikut 97,1%; 96,9%; 97,4%; 96,5% dan 97,1% yang berarti skor presentasi kepuasan sangat tinggi. Dan menunjukkan urutan nilai Gap dari yang terbesar hingga yang terkecil pada kelima dimensi sebagai berikut, sikap tenaga farmasi (-0,11); kinerja tenaga farmasi (-0,09); kemampuan berkomunikasi tenaga farmasi (0,06); jenis informasi obat (-0,1) dan lama waktu pelayanan informasi obat (-0,1).
Hormonal Therapy Treatment Pattern For Breast Cancer Patients At Dr. Moewardi Hospital, Surakarta Luthfiyanti, Niken; Rohmana, Vivin Marwiyati; Khusain, Muhammad Fuad Zidane
Proceeding of the International Conference Health, Science And Technology (ICOHETECH) 2025: Proceeding of the 6th International Conference Health, Science And Technology (ICOHETECH)
Publisher : LPPM Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47701/bfz6xt62

Abstract

Breast cancer is a cancer with a high prevalence and mortality rate in women. One of the main therapies for hormone receptor-positive patients isAdjuvant Endocrine Therapy (AET) in the form of tamoxifen, either alone or in combination. The study aims to determine patient characteristics and patterns of hormonal therapy use.breast cancer patients at Dr. Moewardi Regional Hospital, Surakarta. The study used a randomized controlled study design.cross sectional with technique purposive samplingThe study subjects were 64 breast cancer patients undergoing tamoxifen therapy for at least one month. Data were obtained from medical records and questionnaires, then tested using Chi-Square see the relationship between variables. The results of the study showed that the majority of patients were aged <50 years (60.9%) and were in advanced stages (III–IV) at 57.8%. The most common type of therapy was a combination of chemotherapy and hormones (51.6%), while single hormonal therapy was used in 48.4% of patients. The most frequently used chemotherapy regimen was a combination of Cyclophosphamide & Epirubicin, while the most common hormonal therapy was Tamoxifen + Zoladex. Bivariate analysis showed a significant relationship between age and type of therapy and stage and type of therapy (p<0.05).
Uji Stabilitas dan Uji Hedonik Sediaan Gel Ekstrak Daun Rambusa (Passiflora Foetida L) dengan Variasi Na-Cmc Sebagai Basis Sari, Silvia Mega Kusuma; Rohmana, Vivin Marwiyati; Ardiyantoro, Bagas
Indonesian Research Journal on Education Vol. 5 No. 2 (2025): Irje 2025
Publisher : Fakultas Keguruan dan Ilmu Pendidikan, Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/irje.v5i2.2319

Abstract

Daun rambusa (Passiflora foetida L) dikenal memiliki berbagai khasiat herbal yang dapat dimanfaatkan sebagai bahan aktif dalam sediaan gel. Sediaan gel dipilih karena memiliki penetrasi obat ke dalam kulit lebih baik serta waktu kontak lebih lama dibandingkan sediaan topikal lainnya. Tujuan penelitian ini untuk mengetahui pengaruh variasi konsentrasi Na-CMC terhadap uji stabilitas dan hedonik sediaan gel ekstrak daun rambusa. Metode yang digunakan dalam penelitian ini meliputi formulasi sediaan gel dengan tiga variasi konsentrasi Na-CMC (2%, 2,5%, dan 3%), pengujian stabilitas dengan cycling test selama 6 siklus pada suhu 4⁰C dan 40⁰C, serta uji hedonik. Uji stabilitas mencakup pengamatan perubahan organoleptik, homogenitas, nilai pH, daya sebar, daya lekat, dan viskositas. Sedangkan uji hedonik melibatkan penilaian responden terhadap warna, aroma, dan tekstur gel. Analisis data dilakukan dengan One Way ANOVA untuk melihat perbedaan antara formula dan T-Test Dependent untuk mengetahui stabilitas sediaan gel ekstrak daun rambusa. Hasil penelitian menunjukkan variasi konsentrasi Na-CMC pada ketiga formula sesuai dengan standar terhadap uji organoleptik, homogenitas, pH, daya sebar, daya lekat, dan viskositas. Hasil statistik menunjukkan nilai <0,05 yang berarti terdapat perbedaan signifikan pada uji stabilitas dan hedonik terhadap variasi konsentrasi Na-CMC. Gel ekstrak daun rambusa menunjukkan sifat yang stabil, kecuali FI yang kurang stabil pada viskositas. FIII mendapatkan penilaian tertinggi terhadap parameter warna dan aroma, sedangkan pada tekstur lebih disukai FI.
Uji Efektivitas Antibakteri Ekstrak dan Fraksi Bunga Telang (Clitoria Ternatea L.) terhadap Pertumbuhan Staphylococcus Aureus ATCC 25923: Penelitian Tantri Dwi Lestari; Tatiana Siska Wardani; Vivin Marwiyati Rohmana
Jurnal Pengabdian Masyarakat dan Riset Pendidikan Vol. 3 No. 3 (2025): Jurnal Pengabdian Masyarakat dan Riset Pendidikan Volume 3 Nomor 3 (Januari 202
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jerkin.v3i3.389

Abstract

Acne is a skin disease where the oil glands are blocked by dirt that can be infected by bacteria. One way to cure acne is by using compounds that have antibacterial effects. Butterfly pea flowers contain compounds that are believed to inhibit bacterial growth at a certain percentage. The purpose of this study was to determine the antibacterial effectiveness of butterfly pea flower extracts and fractions in certain concentrations. This type of research uses experimental. This study was divided into 6 groups with 4 different concentrations, namely positive control (Gentamicin), negative control (DMSO 10%), Butterfly pea flower extract (15%, 20%, 30%, 40%), Aquadest Fraction (15%, 20%, 30%, 40%), N-hexane Fraction (15%, 20%, 30%, 40%), and Ethyl acetate fraction (15%, 20%, 30%, 40%). The results of the bacterial inhibition zone data were analyzed using SPSS 26 with a confidence level of 95%. The results of this study indicate that the extract and fraction of butterfly pea flowers provide antibacterial effects on the growth of staphylococcus aureus bacteria at concentrations of 15%, 20%, 30%, and 40%. The best inhibition zone is in the ethanol extract of butterfly pea flowers with an average inhibition zone of 9.3 mm at a concentration of 40%.
Pemanfaatan Serbuk Tempe Non-Lemak sebagai Pangan Fungsional melalui Pemberdayaan Kader PKK Desa Baturan Danang Raharjo; Vivin Marwiyati Rohmana; Kharisma Jayak Pratama
Aksi Nyata : Jurnal Pengabdian Sosial dan Kemanusiaan Vol. 3 No. 1 (2026): Januari : Aksi Nyata : Jurnal Pengabdian Sosial dan Kemanusiaan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/aksinyata.v3i1.2865

Abstract

Regarding the Utilization of Non-Fat Tempeh Powder as a Functional Food Based on Local Potential. The activity was conducted in Baturan Village, Colomadu District, Karanganyar Regency, involving 55 members of the PKK (Family Welfare Empowerment) cadre. The community service method employed a Community-Based Research (CBR) approach combined with Asset-Based Community Development (ABCD). The activities included participatory counseling, group discussions, and evaluation through pre-tests and post-tests. The results demonstrated an increase in knowledge, a shift in attitudes, and a growing awareness among the PKK cadre regarding the importance of functional food based on non-fat tempeh. Furthermore, the cadre emerged as peer educators with the potential to drive program sustainability at the community level. This community service proves that community-based counseling is effective in fostering initial social transformation towards healthier and more self-reliant food consumption patterns.
Analysis Of The Relationship Between Compliance With Antihypertensive Drug Use And The Therapy Output Of Hypertension Patients At The Sangkrah Community Health Center In Surakarta Rosmala Dewi; Vivin Marwiyati Rohmana; Aprilia puteri Santika
International Journal of Health Engineering and Technology Vol. 4 No. 6 (2026): IJHET MARCH 2026
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55227/ijhet.v4i6.628

Abstract

Hypertension is a chronic disease with a high prevalence and remains a major public health problem that requires long-term therapy and optimal blood pressure control to prevent complications. Treatment success is influenced by various factors, including adherence to antihypertensive medication. Poor adherence may result in uncontrolled blood pressure and reduced therapeutic outcomes. This study aimed to analyze the relationship between adherence to antihypertensive medication use and therapeutic outcomes among hypertensive Patients at Sangkrah Primary Health Center, Surakarta. This study employed an observational analytic design with a cross-sectional approach. The study population consisted of hypertensive patients who met the inclusion criteria. Medication adherence was measured using the Morisky Medication Adherence Scale (MMAS-8), while therapeutic outcomes were assessed based on blood pressure records documented in patients' medical files. Data were analyzed using univariate analysis to describe respondent characteristics and bivariate analysis using the chi-square test to examine the association between medication adherence and therapeutic outcomes. The results showed that most respondents were classified as adherent, with 90 respondents (90.0%), while 10 respondents (10.0%) were non-adherent. Regarding therapeutic outcomes, 74 respondents (74.0%) had uncontrolled blood pressure and 26 respondents (26.0%) had controlled blood pressure. Chi-square analysis showed a Pearson Chi-Square value of 0.208 (p > 0.05), indicating no statistically significant relationship between medication adherence and therapeutic outcomes. In conclusion, adherence to antihypertensive medication was not significantly associated with blood pressure control. These findings indicate that blood pressure management is influenced not only by medication adherence but also by factors, comorbidities, and nonpharmacological interventions.
Cost-Effectiveness Analysis Of Pulmicort-Combivent And Pulmicort Single Use In Inpatients With Chronic Obstructive Pulmonary Disease At Dr. Moewardi Regional Hospital Yustina Esha Maunia Chantika; Kharisma Jayak Pratama; Vivin Marwiyati Rohmana
International Journal of Health Engineering and Technology Vol. 4 No. 6 (2026): IJHET MARCH 2026
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55227/ijhet.v4i6.633

Abstract

Chronic Obstructive Pulmonary Disease (COPD) causes a high economic burden due to repeated hospitalizations, but the cost-effectiveness of Pulmicort-Combivent versus Pulmicort alone has not been evaluated at Dr. Moewardi Regional General Hospital. This study aims to determine ACER, ICER, and cost-effectiveness of therapy using CEA. This study was a retrospective, descriptive, cross-sectional observational study with a total sampling of 62 hospitalized COPD patients from January 2024 to November 2025. Medical record data instruments were analyzed using ACER, ICER, and the Mann-Whitney test. The results showed that the ACER of Pulmicort-Combivent Rp225,775 (40% effectiveness) was lower than that of Pulmicort alone Rp765,036 (14.03%), ICER Rp-65,554, with no significant difference (p>0.05). Both therapies were equivalent in terms of cost-effectiveness.
Comparison of Antioxidant Activity of Sheet Mask Ethanol Extract of Kesum Leaves (Polygonum Minus H) Using DPPH and FRAP Methods Ambararum, Tiara Rizki; Annie Rahmatillah; Vivin Marwiyati Rohmana
International Journal of Health Engineering and Technology Vol. 4 No. 6 (2026): IJHET MARCH 2026
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55227/ijhet.v4i6.674

Abstract

Skin aging due to oxidative stress from free radicals requires natural antioxidants such as kesum leaves (Polygonum minus Huds.) which are rich in flavonoids and phenolics. This study aims to formulate a sheet mask from ethanol extract of kesum leaves at a concentration of 1-3%, evaluate the physicochemical properties, and compare antioxidant activity with DPPH and FRAP methods. Quantitative experimental research with a comparative design used purposive sampling of kesum extracts and formulations (F0-F3), with three replications per concentration (a total of 12 samples). Instruments include a UV-Vis spectrophotometer (DPPH 517 nm, FRAP 593 nm), pH meter, viscometer; linear regression data analysis for IC₅₀ and t/ANOVA test. The results showed that the IC₅₀ extract DPPH 38.12 ppm (very strong) and FRAP 67.37 ppm (strong); F3 sheet mask optimal IC₅₀ DPPH 41.59 ppm, pH 5.43, viscosity 385 mPa.s, spreadability 6.7 cm, non-irritant, increased humidity 50-60%. The DPPH method is more sensitive than FRAP. In conclusion, F3 sheet mask has the potential to be a strong antioxidant for anti-aging cosmetics, in vivo and stability tests are recommended.
Co-Authors 'Arifah, Zainul A, Ferlinda Ayu Ambararum, Tiara Rizki Aprilia Puteri Santika Ardiantoro, Bagas Artini, Kusumaningtyas Siwi Bagas Ardiyantoro Danang Raharjo Febriani, Tiffany Aisya Handayani, Sri Insani, Fitri Nur iska olivia, anggun Kharisma Jayak Pratama Khusain, Muhammad Fuad Zidane Kusumasedya, Willyana Pratiwi Listyani, Tiara Ajeng Luthfiyanti, Niken Mahendra, Andika Dwi Monica Permata, Bangkit Riska Phiapresia, Safara Zulfa Pratama, Kharisma Jayak Puspita Sari, Mawar Dela Raden Mohamad Herdian Bhakti Rahmadona, Salsa Permata Rahmat Hidayat Rahmatillah, Annie Rianto, Yeta Pradina Ainun Rosmala Dewi Saputra, Rizka Wahyu Sari, Silvia Mega Kusuma Septian Maulid Wicahco Septiarini, Anita Dwi Tantri Dwi Lestari Tiara Dhea Febryana Wardani, Tatiana Siska Yustina Esha Maunia Chantika