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All Journal Pharmaciana: Jurnal Kefarmasian Jurnal Penelitian Pendidikan IPA (JPPIPA) JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan JURNAL FARMASIMED (JFM) Bali Medika Jurnal Indonesian Journal of Global Health research Widya Kesehatan Medfarm: Jurnal Farmasi dan Kesehatan Indonesian Journal of Pharmaceutical Education Jurnal Pengabdian dan Pengembangan Masyarakat Indonesia Jurnal Kesehatan Terpadu Jurnal Farmasetis Innovative: Journal Of Social Science Research Benzena Pharmaceutical Scientific Journal Bali Medical and Wellness Journal UNBI Mengabdi
Putu Yudhistira Budhi Setiawan
Universitas Bali Internasional
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Sekaa Teruna Teruni as An Agent of Change (AoC) Development of Loloh Cemcem as A Traditional Medicine Dewa Ayu Putu Satrya Dewi; Ni Putu Aryati Suryaningsih; Putu Yudhistira Budhi Setiawan
Indonesian Journal of Global Health Research Vol 6 No 6 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i6.4824

Abstract

The development of phytopharmaceuticals aims to increase the use of traditional medicine through an evidence-based medicine (EBM) approach and enhance clinical and community acceptance. This effort cannot be separated from the role and attitudes of adolescents, such as those in the Sekaa Teruna Teruni (STT) group, who have a strong belief in traditional medicine. STT plays a vital role as Agents of Change (AoC) for traditional medicine unique to Penglipuran Traditional Village, particularly loloh cemcem. Currently, information about loloh cemcem is provided conventionally and is not based on EBM for residents and tourists, highlighting the need for technological innovation in promoting this traditional remedy. This study aims to assess the effectiveness of e-booklets as an educational medium to enhance the knowledge of STT adolescents regarding loloh cemcem and to empower them as Agents of Change in promoting its use. This quantitative descriptive study employs a quasi-experimental one-group pretest-posttest design and was conducted in April-May 2024. The sample included STT members from Penglipuran Traditional Village, selected through purposive sampling based on specific inclusion and exclusion criteria. Inclusion criteria included residency in Penglipuran Traditional Village, active and passive English proficiency, ability to use electronic media and the internet, and obtaining a pretest score of ≥80 points. Exclusion criteria included respondents who could not be reached for the posttest or were unwilling to dedicate time to the AoC loloh cemcem initiative. Data were collected through a validated and reliable knowledge questionnaire with 10 items, and e-booklets were used as educational media. Analysis using SPSS 18 and the Wilcoxon test showed a significant increase in knowledge after the provision of e-booklets (p = 0.001). These results suggest that e-booklets effectively enhance STT adolescents' knowledge, supporting them as key sources of information and promoters of loloh cemcem as a traditional medicine.
The effect of reducing blood sugar levels from Stichopus hermanii on alloxan-induced rats I Putu Gede Adi Purwa Hita; Putu Yudhistira Budhi Setiawan; Ni Kadek Dwi Sri Mahayani
Pharmaciana Vol. 16 No. 2 (2026): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v16i2.30074

Abstract

Stichopus hermanii, or gold sea cucumber, is a marine organism that can be utilized for the treatment of diabetes mellitus. The relationship between observed biological activities and the responsible bioactive compounds is influenced by the solvent used during extraction. The compounds in gold sea cucumber are suspected to reduce blood sugar levels and can dissolve in a polar solvent like water. This study aims to quantitatively evaluate the reduction in blood sugar with the administration of gold sea cucumber water extract by a pretest and posttest control group design method, where treatment groups administered gold sea cucumber water extract in each kilogram rat’s body weight at doses of 45 mg, 90 mg, and 180 mg. Before treatment, rats were induced with alloxan to get diabetic condition. Diabetic rats with blood sugar levels over 200 mg/dL were treated once daily for 28 days orally. Blood sugar levels were measured five times and then blood sugar levels were assessed analytically using the GLM-RM method. The positive control group exhibited a reduction of 84.1%, while treatment groups with doses of 45 mg, 90 mg, and 180 mg showed reductions of 72.4%, 76.7%, and 79.9%, respectively. The negative control group showed a reduction of 1.4%. Statistically significant reductions in blood sugar levels were observed in each group and time parameter (p < 0.05). It can be concluded that gold sea cucumber water extract contains bioactive compounds and effectively reduces blood sugar levels in alloxan-induced male Wistar rats (Rattus norvegicus).
Co-Authors Ahmad Fudholi Ahmad Fudholi Astuti, Ni Wayan Purnami Darmayanti, Ni Putu Ovy Dewa Ayu Putu Satrya Dewi Dewa Ayu Putu, Satrya Dewi Dewi anggarini Dhiancinantyan Windydaca Brata Putri Dwi Agustyarini, Pande Kadek Febryanti, Ekanur I Gusti Ayu Agung Septiari I Gusti Lanang Made Rudiartha I Gusti Ngurah Agung Windra Wartana Putra I Gusti Septiari I Putu Gede Adi Purwa Hita I Putu Gede Adi Purwa Hita I Putu Riska Ardinata I Putu Tangkas Suwantara I Wayan Tanjung Aryasa Maharianingsih, Ni Made Ni Kadek Arinda Ni Kadek Dwi Sri Mahayani Ni Putu Aryati Suryaningsih Ni Putu Juli Martasari Ni Putu Rahayu Artini Ni Putu Widayanti Ni Wayan Yuliasih Oktaviani, Fatikhatul Putri Satibi Satibi Satibi Satibi Suryaningsih , Ni Putu Aryati Sutema, Ida Ayu Manik Partha Wartana Putra, I G.N.A Windra Wartana Putra, I Gusti Ngurah Agung Windra Widowati, I Gusti Ayu Rai - Wintariani, Ni Putu Wintariani, Ni Putu Aryati