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All Journal Pharmaciana: Jurnal Kefarmasian Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Farmasains : Jurnal Ilmiah Ilmu Kefarmasian JRST (Jurnal Riset Sains dan Teknologi) PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Kesehatan Tambusai Jurnal Farmasi Sains dan Praktis Edunity: Kajian Ilmu Sosial dan Pendidikan JTH: Journal of Technology and Health Benzena Pharmaceutical Scientific Journal Praeparandi: Jurnal Farmasi dan Sains
Indri Hapsari
Universitas Muhammadiyah Purwokerto
Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences

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Perbandingan Efektivitas Penangkal Radikal Bebas Ekstrak Beras Merah Dengan Ekstrak Beras Hitam Pada Formula Masker Gel Peel-off Siti Farah Hardiyati; Indri Hapsari; Retno Wahyuningrum
Edunity Kajian Ilmu Sosial dan Pendidikan Vol. 5 No. 8 (2026): Edunity: Social and Educational Studies
Publisher : PT Publikasiku Academic Solution

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57096/edunity.v5i8.558

Abstract

Radikal bebas dapat terbentuk akibat faktor pemicu stres seperti sinar ultraviolet, radiasi, aktivitas fisik, dan stres oksidatif. Untuk mencegah radikal bebas yang tak terkendali, tubuh secara spontan memproduksi zat antioksidan. Namun, ketika kulit terpapar radikal bebas dalam jumlah yang besar dari lingkungan, antioksidan endogen tidak cukup untuk menangkalnya. Salah satu bahan alami yang dapat dimanfaatkan adalah beras. Beras tidak hanya merupakan sumber energi dan protein, tetapi juga sumber vitamin, mineral, asam ferulat, tokoferol, y-oryzanol, dan berbagai antioksidan. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan dalam menangkal radikal bebas dari bahan alami yaitu ekstrak beras merah dan ekstrak beras hitam yang diformulasikan dalam bentuk sediaan masker gel peel-off. Metode yang digunakan untuk menentukan aktivitas antioksidan adalah metode DPPH (2,2-diphenyl-1-picrylhydrazyl). Parameter pengujian yang digunakan meliputi uji organoleptik, uji homogenitas, uji pH, uji viskositas, uji daya sebar, uji waktu pengeringan, uji stabilitas (cycling test), dan uji iritasi. Hasil uji aktivitas antioksidan menunjukkan nilai IC50 sebesar 26,34 ppm untuk ekstrak beras merah dan 26,98 ppm untuk ekstrak beras hitam; sedangkan untuk sediaan masker gel peel-off, nilai IC50 yang diperoleh adalah 29,58 ppm untuk ekstrak beras merah dan 30,53 ppm untuk ekstrak beras hitam. Berdasarkan penelitian ini, disimpulkan bahwa ekstrak beras merah memiliki aktivitas antioksidan yang lebih tinggi dalam menangkal radikal bebas dibandingkan ekstrak beras hitam, baik dalam bentuk ekstrak murni maupun dalam sediaan masker gel peel-off.
Narrative Review : Implementasi Farmakoekonomi dalam Program Kesehatan Stunting Chiara Dhinta; Didik Setiawan; Indri Hapsari
BENZENA Pharmaceutical Scientific Journal Vol 5 No 01 (2026): BENZENA PHARMACEUTICAL SCIENTIFIC JOURNAL
Publisher : Universitas Pekalongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31941/benzena.v5i01.7974

Abstract

Introduction: Stunting is a chronic nutritional problem that remains a major public health challenge in Indonesia because it impacts physical growth, cognitive development, economic productivity, and the quality of human resources. Although the prevalence of stunting shows a downward trend, its incidence remains relatively high, necessitating effective and efficient interventions. A pharmacoeconomic approach, specifically cost-effectiveness analysis (CEA), can be used to evaluate the efficiency of various stunting prevention and management programs. Objective: This narrative review aims to examine the factors that influence the incidence of stunting in children and analyze the implementation of pharmacoeconomics through a cost-effectiveness analysis approach in various stunting control programs. Methods: The study was conducted using a narrative review method with secondary data sources obtained from the PubMed, Google Scholar, and ScienceDirect databases. The literature search was conducted on publications from 2008–2026. Articles that met the inclusion criteria included observational studies, cohort studies, systematic reviews, meta-analyses, and economic evaluation studies related to stunting programs. A total of 30 articles were analyzed descriptively. Results: The study showed that stunting is influenced by nutritional factors, recurrent infections, low birth weight, maternal nutritional status, maternal education, socioeconomic conditions, and environmental sanitation. Interventions such as micronutrient supplementation, supplementary feeding, exclusive breastfeeding promotion, nutrition education, and sanitation improvements have been proven effective in reducing the risk of stunting. Cost-effectiveness analysis showed that interventions in the First 1,000 Days of Life provide significant health and economic benefits with efficient use of resources. Conclusion: Implementing pharmacoeconomics through cost-effectiveness analysis plays a crucial role in supporting decision-making for stunting reduction programs. Nutrition and health interventions in early life have proven effective and provide long-term economic benefits, making them worthy of prioritization in public health policies. Keywords: Stunting; Pharmacoeconomics; Cost-Effectiveness Analysis; Nutrition Program; Child Health
Narrative Review: Penerapan Sistem Key Performance Indicators untuk Pengelolaan Apotek yang Optimal Dinda Farida; Indri Hapsari; Erza Genatrika
BENZENA Pharmaceutical Scientific Journal Vol 5 No 01 (2026): BENZENA PHARMACEUTICAL SCIENTIFIC JOURNAL
Publisher : Universitas Pekalongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31941/benzena.v5i01.7976

Abstract

Background: Pharmacies, as pharmaceutical service facilities, are expected to provide quality services amid increasing operational complexity and public expectations. Challenges like dispensing errors, non-compliance with service standards, and inefficiencies in inventory management can affect patient safety and operational sustainability. Therefore, data-based performance measurement tools are needed to support continuous quality improvement. Objective: This narrative review is prepared to examine the basic concepts of KPIs in pharmaceutical services, identify relevant indicators along with factors that influence their implementation, and formulate a framework for applying KPI based on the Balanced Scorecard in pharmacies. Method: The research uses a narrative review method with a descriptive-qualitative approach. Literature was obtained from Google Scholar, PubMed, and ScienceDirect using keywords related to KPI, pharmacy management, Balanced Scorecard, and pharmaceutical services. Articles that met the inclusion criteria were analyzed to identify KPI indicators, supporting and inhibiting factors, and implementation strategies. Results: The study results indicate that pharmacy KPIs can be classified into four main domains: operational, clinical, financial, and patient satisfaction. KPI implementation is influenced by supporting factors such as managerial leadership, human resource readiness, the availability of integrated information systems, and the suitability of indicators to the local context. Conversely, major obstacles include staff's lack of understanding of the KPI concept, limitations in digital recording systems, and the lack of standard KPIs for community pharmacies. The implementation of the Balanced Scorecard framework is considered relevant for integrating various perspectives of pharmacy performance in a comprehensive and measurable manner. Conclusion: KPIs are an effective tool for objectively measuring and improving pharmacy performance. Implementing Balanced Scorecard-based KPIs has the potential to improve the quality of pharmaceutical services and support the sustainability of pharmacy operations.
Analysis of The Effect of Medication Therapy Management on Tuberculosis Patients Reza Nur Iman; Githa Fungie Galistiani; Indri Hapsari
BENZENA Pharmaceutical Scientific Journal Vol 5 No 01 (2026): BENZENA PHARMACEUTICAL SCIENTIFIC JOURNAL
Publisher : Universitas Pekalongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31941/benzena.v5i01.7986

Abstract

Background: Tuberculosis (TB) remains a global health problem with high incidence and mortality rates. The success of TB therapy is greatly influenced by patient adherence to long-term treatment. Medication Therapy Management (MTM) has been developed as a pharmaceutical care approach focused on optimizing medication use and improving patient outcomes. Objective: This review aims to analyze the impact of Medication Therapy Management implementation on treatment outcomes in tuberculosis patients and identify opportunities and challenges for its implementation in healthcare practice. Method: This study was conducted using a narrative review method by searching scientific articles from the PubMed, Google Scholar, Frontiers, and ScienceDirect databases. Articles published between 2016 and 2026 that discussed the implementation of MTM in tuberculosis patients were selected based on predetermined inclusion criteria. A total of 15 articles met the criteria and were analyzed descriptively. Results: The review indicates that the implementation of MTM has contributed to improving treatment adherence, identifying and addressing drug-related problems, improving monitoring of drug side effects, and supporting the success of TB patient therapy. Pharmacist interventions through MTM components have also been reported to have the potential to improve patient quality of life and strengthen collaboration among healthcare professionals. However, MTM implementation still faces various obstacles, such as limited human resources, suboptimal documentation systems, and poor patient understanding of therapy. Conclusion: Medication Therapy Management has demonstrated benefits in supporting successful tuberculosis treatment by improving adherence, safety, and effectiveness of therapy. Strengthening the role of pharmacists and providing support from the health system is needed to optimize MTM implementation in TB patients. Keywords: Medication Therapy Management; Tuberculosis; Treatment Adherence; Pharmacists; Therapy Outcomes
Co-Authors Agus Siswanto Aldhi Solihin Abd. Karim Ali Nurrohim Anggita Nur Fauzana Anis Kusumawati Anjar Mahardian Kusuma Anwar Rosyadi Binar Asrining Dhiani Budiman, Arif Caesar, Rahma Yuanita Chiara Dhinta Desy Sapmaimy Didik Setiawan Dinda Farida Djoko Wahyono Djoko Wahyono eva rosmawati Eva Rosmawati Gayuh Kurniawan Genatrika, Erza Ghaliyah Kusuma Wardani Githa Fungie Galistiani Githa Fungie Galistiani Hidayah Anisa Fitri Ika Yuni Astuti Irsalina Nurul Putri Irsalina Nurul Putri Isna Nurkhikmah nur annisa septyaningrum Pri Iswati Utami R. Adi Soeprijanto Rahma Yuanita Caesar Retno Wahyuningrum Reza Nur Iman Saturi Siti Farah Hardiyati Susmiatun Susmiatun susmiatun, susmiatun Sustiawati _ Wahyu Utaminingrum Wiryanto yusni ulfiani zulaikha Yusni Ulfiani Zulaikha