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All Journal CAKRA KIMIA (Indonesian E-Journal of Applied Chemistry) JURNAL KIMIA SAINS DAN APLIKASI Pharmaciana: Jurnal Kefarmasian THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST Jurnal Penelitian Pendidikan IPA (JPPIPA) Martabe : Jurnal Pengabdian Kepada Masyarakat Jurnal RESISTOR (Rekayasa Sistem Komputer) Jambura Journal of Chemistry Jurnal Media Sains Jurnal ABDINUS : Jurnal Pengabdian Nusantara An-Nadaa: Jurnal Kesehatan Masyarakat Jurnal Widya Biologi Jurnal Ilmiah Medicamento Jurnal Mandala Pengabdian Masyarakat Poltekita: Jurnal Pengabdian Masyarakat INDRA: Jurnal Pengabdian kepada Masyarakat Jurnal Ilmiah Berkala Sains dan Terapan Kimia Jurnal Kesehatan Terpadu Molekul: Jurnal Ilmiah Kimia Jurnal Tumbuhan Obat Indonesia Jurnal Kesehatan Marendeng UNBI Mengabdi Bali International Scientific Forum Jurnal Sains dan Teknologi Pangan
I Wayan Tanjung Aryasa
Universitas Bali Internasional
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary

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- IN SILICO STUDY OF DERIVATIVE COMPOUNDS OF GALANGAL PLANTS AS ANTI-INFLAMMATORY I Wayan Tanjung Aryasa; I Kadek Arya Sugianta
Jurnal Penelitian Pendidikan IPA Vol 9 No 8 (2023): August
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i8.3042

Abstract

A Inflammation is the basis of pathogenesis of several diseases, both degenerative and non-degenerative diseases. Galangal plants which are commonly found in Indonesia are commonly used as traditional medicines for several diseases and also have secondary metabolite compounds that are useful as anti-inflammatory. In this study, an in silico approach in the form of molecular docking has been applied to 5 compounds derived from the galangal plant to important inflammatory molecular targets such as the cyclooxygenase-2 (COX-2) receptor. Analysis of the biological activity of compounds derived from the galangal plant using the WAY2DRUG PASS prediction server. Prediction results of physicochemical properties of compounds derived from galangal plant using the SWISS-ADME server. This study aims to predict the ability of 5 compounds derived from the galangal plant to inhibit the COX-2 enzyme. Detailed information has been obtained using a molecular docking approach. Docking simulations for 5 compounds derived from the galangal plant have been carried out through the Autodock 4.2 application which is embedded in the MGL Tools 1.5.6 application. The molecular interactions of compounds derived from galangal against COX-2 receptors were visualized using Discovery Studio (Biova) software. Based on the results of the research that has been carried out, it can be concluded that the test compound Galanganal has the best affinity when compared to the compounds Galanganol A, Galanganol B, Galanganol C and Galangin. This can be seen from the bond free energy value of -8.98 kcal/mol and the inhibition constant of 261.59 nM. These results indicate that the Galanganal test compound has potential as an anti-inflammatory agent. However, further research is needed to study more compounds derived from the galangal plant to isolate the best conformation.
Pengetahuan dan Sikap Siswa SMA Terhadap Pemeriksaan Laboratorium dalam Penegakan Diagnosis Infeksi Menular Seksual di Provinsi Bali Ni Made Sri Dwijastuti; Ni Putu Senshi Septiasari; IGAA Satwikha Dewi; I Wayan Tanjung Aryasa; Gde Palguna Reganata; Aprilia Rakhmawati
An-Nadaa: Jurnal Kesehatan Masyarakat (e-Journal) Vol 13, No 1 (2026): AN-NADAA JURNAL KESEHATAN MASYARAKAT (JUNI)
Publisher : Universitas Islam Kalimantan Muhammad Arsyad Al Banjari Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31602/ann.v13i1.23041

Abstract

Background: Enhancing laboratory-based early detection of sexually transmitted infections (STIs) is a critical element of STI control strategies. The effectiveness of diagnostic systems relies not only on technical capacity but also on population knowledge and acceptance of laboratory testing. Objective: To examine high school students’ knowledge and attitudes toward STI laboratory examinations according to respondent characteristics, serving as indicators of diagnostic literacy among adolescents. Methods: This observational analytical study employed a cross-sectional design. The sample comprised high school and vocational high school students selected by their schools to participate in data collection and complete the questionnaire fully. Data were gathered using a structured questionnaire assessing knowledge and attitudes toward STI laboratory testing. Analyses evaluated differences by school type, region, and gender. Results: No significant differences in knowledge or attitudes were identified by school type or geographic location. A significant difference emerged only in attitudes by sex, exhibiting a small effect size. Conclusion: The distribution of knowledge and attitudes indicates comparable levels of diagnostic literacy across schools and regions. Variation in attitudes by sex suggests differences in acceptance of laboratory examinations. Diagnostic literacy constitutes a critical component in enhancing laboratory-based early detection systems for STIs.
Pengetahuan dan Sikap Siswa SMA Terhadap Pemeriksaan Laboratorium dalam Penegakan Diagnosis Infeksi Menular Seksual di Provinsi Bali Ni Made Sri Dwijastuti; Ni Putu Senshi Septiasari; IGAA Satwikha Dewi; I Wayan Tanjung Aryasa; Gde Palguna Reganata; Aprilia Rakhmawati
An-Nadaa : Jurnal Kesehatan Masyarakat (e-Journal) Vol 13 No 1 (2026): AN-NADAA JURNAL KESEHATAN MASYARAKAT (JUNI)
Publisher : Universitas Islam Kalimantan Muhammad Arsyad Al Banjari Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31602/ann.v13i1.23041

Abstract

Background: Enhancing laboratory-based early detection of sexually transmitted infections (STIs) is a critical element of STI control strategies. The effectiveness of diagnostic systems relies not only on technical capacity but also on population knowledge and acceptance of laboratory testing. Objective: To examine high school students’ knowledge and attitudes toward STI laboratory examinations according to respondent characteristics, serving as indicators of diagnostic literacy among adolescents. Methods: This observational analytical study employed a cross-sectional design. The sample comprised high school and vocational high school students selected by their schools to participate in data collection and complete the questionnaire fully. Data were gathered using a structured questionnaire assessing knowledge and attitudes toward STI laboratory testing. Analyses evaluated differences by school type, region, and gender. Results: No significant differences in knowledge or attitudes were identified by school type or geographic location. A significant difference emerged only in attitudes by sex, exhibiting a small effect size. Conclusion: The distribution of knowledge and attitudes indicates comparable levels of diagnostic literacy across schools and regions. Variation in attitudes by sex suggests differences in acceptance of laboratory examinations. Diagnostic literacy constitutes a critical component in enhancing laboratory-based early detection systems for STIs.
Co-Authors Adi Putra, I Made Surya Agus Mahardiananta, I Made Agus Riki Gunawan, I Kadek Aprilia Rakhmawati Arya Sugiantara, I Kadek Ayu Saka Laksmita W Costav, Sandra Da Desak Putu Risky Desak Putu Risky Vidika Apriyanthi Dewi, Dewa Ayu Trisna Dewi, I Gusti Agung Ayu Satwikha Dwi Aprilianti, Ni Kadek Dwijastuti, Ni Made Sri Hendrayana, I Made Dwi I GUSTI AGUNG AYU SATWIKHA DEWI - I Kadek Agus Riki Gunawan I Made Dwi Hendrayana IGAA Satwikha Dewi Indra Noviandri Iriani, Yulidia Kartiningsih, Ni Luh Eka L., Yulidia Iriani Made Sri Dwijastuti, Ni Mete, Fransisca Inya Wanda Ni Kadek Mona Fujiastuti Hendriani Ni Made Sri Dwijastuti Ni Putu Dinda Setiawati Ni Putu Linda Juli Artaningsih Ni Putu Puniari Eka Putri, Ni Putu Puniari Eka Ni Putu Rahayu Artini Ni Putu Saraswati Kristina Ni Putu Widayanti Ni Putu Widiantari Paulina Kadam Prihananta, Putu Deva Puniari Eka Putri, Ni Putu Putu Gede Ayu Erika Juliari Putu Lakustini Cahyaningrum Putu Puniari Eka Putri, Ni Putu Widiantari, Ni Putu Yudhistira Budhi Setiawan rahayu artini yuan Rasmi, Kadek Anidia Reganata, Gde Palguna Risky Vidika A sabakthani kayoi Septiasari, Ni Putu Senshi Sugianta, Kadek Arya Vidika A, Risky Vidika, Desak Putu Risky Widiantari, Ni Putu Yulidia Iriani Yulidia Iriani L.