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All Journal African Multidisciplinary Journal of Sciences and Artificial Intelligence African Journal of Biochemistry and Molecular Biology Research African Journal of Sciences and Traditional Medicine Kwaghe International Journal of Sciences and Technology Kwaghe International Journal of Arts, Humanities and Religious Studies African Journal of Medicine, Surgery and Public Health Research
Kingsley Iyoko Iseko
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Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences

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Public Knowledge, Attitude And Acceptability of COVID-19 Vaccine among Traders in Wuse Market Abuja: A Cross-Sectional Study Tensaba Andes Akafa; Gloria Omonefe Oladele; Kingsley Iyoko Iseko; Vika Tensaba Akafa; Izam Emmanuel David; Oche Williams Ujah; Tongle Nanle John; Chakfa Nanmar; Lawal Danjuma Tyem; Isaac John Umaru
African Journal of Medicine, Surgery and Public Health Research Vol 1 No 1 (2024): African Journal of Medicine, Surgery and Public Health Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajmsphr.v1i1.3976

Abstract

The effect of the COVID-19 pandemic on public health has been unpleasant. Vaccination is a critical measure to decrease COVID-19 economic loss and public health burden. This is very helpful to control the COVID-19 pandemic. The process of halting COVID-19 solely depends on population uptake of the vaccination process and the adoption of non-pharmacological measures. This in turn relies on the public willingness to get vaccinated. The public acceptability of this vaccination is further determined by the level of knowledge and trust in currently available COVID-19 vaccines. Therefore, this paper aims to discuss the findings of public knowledge, attitude, and acceptability of COVID-19 vaccines among traders in Wuse Market Abuja. A cross-sectional study was conducted among different traders in the Abuja Wuse Market to assess their knowledge, attitude and level of acceptability toward COVID-19 vaccinations using a self-administered survey questionnaire with the following four sections; socio-demographic characteristics, knowledge assessment questions, attitude assessment, and acceptability questions. A total of 166 participants completed the questionnaire. The knowledge of the COVID-19 vaccinations among the study participants was high with 143(86%) respondents stating that they knew about COVID-19 vaccinations. Among the traders that participated, 74(44.36%) believed that vaccines are safe and 109 (66.02%) agreed that vaccines are critical to protect the public from COVID-19 infection. But only, 45 (27.4%) accept to receive the vaccine. Participants’ attitudes, knowledge, and level of acceptability were significantly affected by age, gender, education level, and marital status (P <0.001). Our findings suggest that there is good knowledge and attitude toward the vaccination process against COVID-19 among study participants in spite of low acceptability. Awareness campaigns are therefore necessary to disseminate reliable knowledge about COVID-19 vaccines and demystify the COVID-19 conspiracy theory in order to raise the level of vaccination acceptance.
Influence of Emotional Intelligence on the Mental Health of the Federal Road Safety Corps Personnel in Benue State Sector Command Danladi Zakariah; Elvis O. Ihaji; Tensaba Andes Akafa; Vika Tensaba Akafa; Kingsley Iyoko Iseko; Gloria Omonefe Oladele
African Journal of Medicine, Surgery and Public Health Research Vol 1 No 1 (2024): African Journal of Medicine, Surgery and Public Health Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajmsphr.v1i1.3977

Abstract

This study examined Emotional Intelligence on the Mental Health of the Federal Road Safety Corps Personnel in Benue State Sector Command. The study employed a cross-sectional survey design in which 232 Federal Road Safety Corps Personnel whose ages ranged from 20 – 58 years (Mean age=36.30, SD=8.34), comprising 169(72.8%) males and 63(27.2%) females who served as participants for the study. Emotional intelligence Scale and Mental Health Inventory scale were used in data collection. The result of the finding shows that, there was a significant positive influence of emotional intelligence on mental health of Federal Road Safety Corps Personnel in Benue State Sector Command [R=.436, R2=.190, F (5,227) =3.627, p<.01]. The result also indicated that, emotional intelligence and its dimensions explained 19.0% of the variance observed in mental health among the participants. This means that, Federal Road Safety Personnel with high levels of emotional intelligence are likely to have good mental health, and the extent to which emotional intelligence explains mental health of Federal Road Safety Corps Personnel in Benue State Sector Command is 19.0%, and based on this finding, the second hypothesis was confirmed. Independently, findings revealed that, social skills made the highest significant contribution (β=.299, t=2.988, p<.05), followed by motivation (β=.223, t=2.588, p<.05), and then self-reputation (β=.211, t=2.081, p<.05), followed by social awareness (β=.198, t=1.758, p<.05), and self-awareness (β=.180, t=1.313, p<.05) successively. Based on this finding, it was recommended that the management of Federal Road Safety Corps in Benue State Sector should explore ways of improving the personnel's emotional intelligence deficit which may enhance succees and improve their mental health.
The Effect of Aqueous Solution of Hibiscus sabdariffa (Zobo Drink) on Albino Wistar Rats Ovarian Tissue Tensaba Andes Akafa; Williams Oche Ujah; Isaac Kogi Eli; Charles Ayara; Victor Makanjuola; Queen Uyo Williams; Dafup Katdel Istifanus; Vika Tensaba Akafa; Izam Emmanuel David; Kingsley Iyoko Iseko; Ranyang R. Akafa
African Journal of Medicine, Surgery and Public Health Research Vol 1 No 1 (2024): African Journal of Medicine, Surgery and Public Health Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajmsphr.v1i1.4011

Abstract

Hibiscus sabdarrifa is a flowering plant that grows in tropical regions. It is used in the preparation of a non-alcoholic beverage called Zobo drink. This current study investigated the ovarian histological changes and hormonal level outcome that occur after administration of Hibiscus sabdarrifa aqueous solution (Zobo drink) on albino Wistar rat. Twenty (20) female Wistar rats were purchased and divided into five (5) groups, group A, group B, group C, group D and group E with each group having four (4) Wistar rats. Group A, the control group was unexposed to any form of foreign substance. Group B were given 0.5ml of Zobo drink once daily (morning). Group C were given 0.5ml of Zobo drink twice daily (morning and afternoon). Group D were given 0.5ml of Zobo drink three times daily (morning, afternoon and evening). Group E were given the Zobo drink concurrently all through the day and water only at night. In the end, the rats were sacrificed and the ovaries were removed and fixed in 10% formalin saline solution. The ovaries were stained with hematoxylin and eosin. Their blood was collected through the femoral artery for hormonal level assay. The histological result of group A, B, C and D showed normal histological structures. Group E showed hemorrhage in the corpus luteum of the ovaries. The result of the hormonal analysis showed an increase in the level of progesterone, follicle stimulating hormone and luteinizing hormone and decrease in the level of estrogen all through the five groups. This lower estrogen level could impede menstruation. Therefore, Zobo drink can damage the ovary if taken in excess quantity and cause fluctuation in hormonal level of the ovary.
Psychoeducation of the Nigeria Population on Knowledge of Substance Abuse, Drug Addiction and Regular Medical Check-Up Danladi Zakariah; Tensaba Andes Akafa; Vika Tensaba Akafa; Gloria Omonefe Oladele; Kingsley Iyoko Iseko; Izam Emmanuel David; Oche Williams Ujah; Ndentang Ira Gadin
African Journal of Medicine, Surgery and Public Health Research Vol 1 No 1 (2024): African Journal of Medicine, Surgery and Public Health Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajmsphr.v1i1.4078

Abstract

This paper aims to enhance psychoeducation among the Nigerian population regarding substance abuse, drug addiction, and the importance of regular medical check-ups. Substance abuse and drug addiction are significant contributors to various medical health conditions and mental disorders within the Nigerian populace. Many of these conditions could potentially be prevented or managed effectively if early detection of abnormal neurotransmitter changes in the brain was facilitated through routine medical examinations. This study highlights the alarming scarcity of knowledge and poor attitudes towards substance abuse, drug addiction, and regular medical check-ups in Nigeria, as evidenced by empirical data from psychiatric research. Such deficiencies hinder individuals from making informed health decisions and recognizing risk factors associated with unhealthy lifestyles. According to the World Health Organization, as well as the International Classification of Diseases (ICD-11) and the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), substance abuse and drug addiction are classified as diseases that require treatment, akin to conditions such as diabetes, cancer, heart disease, and HIV. In light of this, the paper calls on the government, as well as the management of healthcare institutions, clinical psychologists, and other healthcare professionals, to prioritize intensive psychoeducation initiatives. These initiatives should focus on raising awareness about the dangers of substance abuse and drug addiction, as well as preventative measures. Moreover, the government and health institutions should collaborate with philanthropists to establish more psychiatric hospitals and rehabilitation centre, providing testing equipment and medications at subsidized rates across all healthcare levels. This would enable individuals struggling with substance abuse and addiction to access necessary services, gain insights into their health status, improve their overall well-being, and alleviate the catastrophe financial burdens faced by their families and loved ones. In conclusion, this paper emphasizes the urgency of addressing these issues and provides actionable recommendations for creating a more informed and supportive environment for those affected by substance abuse and addiction.
Assessment of Anti-Hepatitis B Virus Activity of Leaf Extract of Morinda Citrifolia Isaac John Umaru; Ismail Yunusa Yuguda; Ocheifa Mathew Ngbede; Kingsley Iyoko Iseko; Lubabatu Abdulrasheed; Tensaba Andes Akafa; Ameh Godwin Okwori
African Journal of Medicine, Surgery and Public Health Research Vol 2 No 1 (2025): African Journal of Medicine, Surgery and Public Health Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajmsphr.v2i1.4593

Abstract

Hepatitis B virus infection remains a global health problem, it is a leading cause of liver disease and a possible worldwide source of severe morbidity and mortality. The current standard therapy using interferons or antiviral agents is not successful in all cases and is associated with severe side effects. Consequently, the development of new medicines for the treatment of HBV is still relevant. This experimental study was therefore performed to assess the anti-hepatitis B virus (HBV) potential of Leaf extract of Morinda citrifolia. The methanolic extracts of the Leaf extract of Morinda citrifolia first assessed for cytotoxicity on HepG2.2.15 cells and cytotoxicity concentration (CC50) values were resolved. The methanolic extracts of the Leaf extract of Morinda citrifolia was additionally examined on HepG2.2.15 cells for anti-HBV potential by examining the inhibition of HBsAg and HBeAg production in the culture supernatants, and calculating their half-maximum inhibitory concentration (IC50) and therapeutic index (TI) values. Out of four concentration only three exhibit inhibition of HBsAg production in an increasing dose and time dependent manner. These four concentrations are 100 μg/mL, 200 μg/mL, 300 μg/mL and 400 μg/mL, with IC50 values of 21.15, 24.51, 118.94, 17.65, 20.93 μg/mL, respectively. Moreover, the presence of terpenoids, tannins, alkaloids and flavonoids that could contribute to antiviral efficacy was validated with a qualitative phytochemical study of active extracts.
Antihypertensive Effects of Ethanol Stem-Bark Extract of Morinda Citrifolia in Rats Isaac John Umaru; Ameh Godwin Okwori; Ocheifa Mathew Ngbede; Lubabatu Abdulrasheed; Kingsley Iyoko Iseko; Tensaba Andes Akafa
African Journal of Medicine, Surgery and Public Health Research Vol 2 No 1 (2025): African Journal of Medicine, Surgery and Public Health Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajmsphr.v2i1.4594

Abstract

The medical term used for blood pressure is Hypertension (HTN). Hypertension is a common problem faced by most people today. The leading danger for many diseases such as CVD (cardiovascular) disorder and stroke is high blood pressure. Major diseases like CHF (congestive heart failure), renal disease and blindness can also be caused by HTN. Awareness of plant-based medication therapeutics is continuously increasing day by day. Morinda citrifolia L (Noni) has been used in folk remedies by Polynesians for over 2000 years, and is reported to have a broad range of therapeutic effects. The purpose of this study is to investigate the hypotensive potential of Morinda citrifolia L (Noni) (Family: Rubiaceae) in both normotensive and hypertensive rats. Methods: Aqueous-methanol (70:30) extract of Morinda citrifolia L stem-bark extract at doses of 25, 50, 75 and 100 mg/kg was evaluated for its effect on blood pressure and heart rate using non-invasive blood pressure measuring apparatus. After initial screening, 100 mg/kg dose that produced a maximum effect was selected for the antihypertensive study. Median lethal dose (LD50) and sub-chronic toxicity of the extract were also determined. Various biochemical parameters and organ weight were measured using standard procedures. Results: The extract produced a significant (p < 0.01) decrease in systolic blood pressure (SBP), mean blood pressure (MBP), diastolic blood pressure (DBP) and heart rate of normotensive rats at all test doses with maximum effect at 100 mg/kg. Similarly, a significant antihypertensive and negative chronotropic effect was observed in both hypertensive models. LD50 of the extract was 200 mg/kg in mice. The extract also exhibited a reduction (p < 0.05) in serum alanine transaminase (ALT), aspartate aminotransaminase (AST), alkaline phosphatase (ALP), triglycerides and low-density lipoprotein (LDL) levels while a significant (p < 0.05) increase in high density lipoproteins (HDL) level was observed. Conclusion: It seems that the aqueous-methanol stem-bark extract of Morinda citrifolia L possesses active compounds which may be responsible for the antihypertensive and negative chronotropic effects in rats.
Unpacking the Pain: Understanding Barriers and Unmet Needs of Adults with Low Back Pain in a Southern Nigeria Outpatient Clinic Obianuju Iheomamere Muoghallu; Akaninyene Mark; Tensaba Andes Akafa; Gloria Omonefe Oladele; Kingsley Iyoko Iseko
African Journal of Medicine, Surgery and Public Health Research Vol 2 No 1 (2025): African Journal of Medicine, Surgery and Public Health Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajmsphr.v2i1.4610

Abstract

Background: Low back pain (LBP) is a prevalent health issue leading to functional disability in adults. This study aimed to evaluate the barriers to care and unmet needs of adults with LBP and functional disability attending the General Out-Patient Clinic (GOPC) at the University of Uyo Teaching Hospital, Akwa Ibom State. The goal is to enhance quality of life by reducing disability and LBP burden through prevention, addressing barriers, and fulfilling unmet needs. Key barriers identified include limited access to healthcare, high out-of-pocket costs, inadequate insurance coverage, and a lack of understanding of LBP and self-management strategies. Methodology: Conducted at the GOPC, this cross-sectional analytical study involved 370 adult patients (18+ years) using systematic sampling. Data collection spanned two months, employing an interviewer-administered semi-structured Oswestry lumbar disability questionnaire. Analysis utilized IBM SPSS version 27, with frequency tables for pain patterns and chi-square tests to assess associations between body mass index (BMI) and LBP severity. Results: The mean age of respondents was 40.2 years. LBP was significantly linked to low function, with the association strengthening over time. Most respondents were classified as obese (BMI 25.0-29.9 kg/m²), and 56.7% reported high pain intensity. Activities like lifting weights and sitting exacerbated pain for 70.3% and 66.2% of respondents, respectively. The median pain score was 52, with significant differences noted (p<0.001). Alcohol consumption was reported by 39.6% (p=0.005), while 72.2% did not smoke. Respondents with LBP were 1.70 times more likely to experience functional disability compared to those without. Conclusion: LBP is strongly associated with functional disability among adults. Unmet needs include limited rehabilitation access, inadequate education on LBP, and insufficient support for self-management. Addressing risk factors, implementing multi-modal pain management strategies, and enhancing health education are essential for preventing functional disability.
Co-Authors Abdulmumin Jabir Adeseye Helen Oluwabunmi Adetoyi Moses Gbadebo Ahmad Alhassan Siddan Ajala-Lawal R. A Akaninyene Mark Aliyu Olamilekan Najeeb Ameh Godwin Okwori Arowora Kayode Adebisi Bilyaminu Habibu Chakfa Nanmar Charles Ayara Dafup Katdel Istifanus Danladi Zakariah Elvis O. Ihaji Emmanuel Alooma Emmanuel Askeb-nde Joel Emmanuel Askebnde Joel Ezugwu Hilary Chikata Gloria Omonefe Oladele Imo Chinedu Isaac John Umaru Isaac Kogi Eli Ismail Yunusa Yuguda Izam Emmanuel David Jankada Patience Audu Lawal Danjuma Tyem Lazaru Joseph Goje Lubabatu Abdulrasheed Maianguwa Abdulrsashid Dauda Maryam Usman Ahmed Mgbede Timothy Moses Adondua Abah Muhammad Zuhairah Ismail Ndentang Ira Gadin Nkechi Gift Ijeomah Obianuju Iheomamere Muoghallu Oche Williams Ujah Ocheifa Mathew Ngbede Okpanachi Nuhu Oyibo Olabanji Martina Morolake Queen Uyo Williams Ranyang R. Akafa Rashida Ismail Mohammed Selumun Solomon Ipav Shadrach Philip Sulaiman Abubakar Aliyu Tensaba Andes Akafa Tongle Nanle John Ubur Terzulum Wilson Victor Makanjuola Victoria Ifeoluwa Ayo Vika Tensaba Akafa Williams Oche Ujah