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Jurnal Ilmiah Kedokteran Wijaya Kusuma

JIKW
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Published by Universitas Wijaya Kusuma Surabaya

ISSN : 19782071 EISSN : 25805967 DOI : -

Core Subject : Health, Science,

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health

Jurnal Ilmiah Kedokteran Wijaya Kusuma (JIKW) is a periodically scientific publication that contains articles written in Indonesia or english. JIKW receive articles in the scope of Biomedical Sciences, degenerative diseases, infections, congenital abnormalities and public health. JIKW published twice a year. The articles will be published in JIKW only manuscript that has never be published or published in other journal. Writers who will publish the article please follow the JIKW guidelines. The entire management process both admission and review the article is done by online.

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Articles 390 Documents

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The Effect of Patin Fish Oil Extract on LDL Cholesterol Levels Rattus norvegicus was Induced by Alloxan Salsabila Yumna Fathony; Fitri Handajani; Indri Ngesti Rahayu
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 11, No 2 (2022): SEPTEMBER 2022
Publisher : Universitas Wijaya Kusuma Surabaya

Diabetes mellitus is a chronic hyperglycemic syndrome that can be accompanied by lipid metabolism disorders. Alloxan is a diabetogenic agent that is associated with an increase in LDL cholesterol levels. Patin fish contain omega-3 and oleic acid, which can potentially reduce or control LDL cholesterol levels. This study aims to determine the effect of Patin fish (Pangasius hypothalmus) oil extract on LDL cholesterol levels of alloxan-induced Rattus norvegicus. The method of this study is the post-test-only control group design. Twenty-seven experimental animals were divided into 3 groups; (1) the 1st group was without treatment, (2) 2nd group was induced with 150 mg/kg BW alloxan on the 7th day; (3) 3rd group was induced with 150 mg/kg BW alloxan on the 7th day and given the Patin fish oil extract at a dose of 73 mg/kg BW on the 10th day for 14 days. Blood samples were taken on the 24th day to determine LDL cholesterol levels. The results of the One-Way ANOVA test showed a significant mean difference, p=0,001 (p<a). The results of the Post-Hoc LSD test showed a meant difference between the 1st group and the 2nd control group p=0,001 (p<a); 2nd group and 3rd group p=0,026 (p<a); between the 1st group and the 3rd group p=0,015 (p<a). Giving alloxan 150 mg/kg BW can significantly increase LDL cholesterol levels of Rattus norvegicus and administration of Patin fish oil extract 73 mg/kg BW can significantly reduce LDL cholesterol levels of Rattus norvegicus.

Use of the Bacterial Names Anaysis According to Historical and Etymological Aspects to Facilitate the Memorization Akhmad Sudibya
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 3, No 1 (2014): Edisi Maret 2014
Publisher : Universitas Wijaya Kusuma Surabaya

Medical students should know two aspects of every bacterial names. The two aspects are etymological aspect and historical aspect. Knowledge of these aspects would facilitate the students in memorizing bacterial names.

Cover September 2022 Putu Oky ari Tania
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 11, No 2 (2022): SEPTEMBER 2022
Publisher : Universitas Wijaya Kusuma Surabaya

Pengaruh Spirulina terhadap VEGF dari Trofoblast Tikus Putih Hamil Strain Wistar yang Diinduksi Interleukin 6 Harry K Gondo; Elizabeth Haryanti
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 9, No 2 (2020): SEPTEMBER 2020
Publisher : Universitas Wijaya Kusuma Surabaya

Preeclampsia is a pregnancy disorder with hypertension as one of its common symptoms. Preeclampsia in pregnancy is characterized by increasing of proteinuria, blood pressure and also interleukin 6. Spirulina sp is a thread like shaped blue-green algae, similar to chain of cylindrical cells with 1 to 12 μm diameter of cell membrane. The purpose of this research was to know the effect of spirulina on VEGF level in improving of trophoblast function in pregnant white Rats Wistar. The design of the study was laboratory experimental with post-test only control group design. Twenty-five rats with preeclampsia model induced by interleukin 6, were divided into 5 groups. The groups were control group, positive control group (P0) injected by interleukin-6 dose of 5 ng/ 100 gram body weight (BW), group with spirulina dose of 10 mg/100 gram BW (P1), group with spirulina dose of 20 mg/100 gram BW (P2); and group with spirulina dosage 40 mg/100 gram BW (P3). The Vascular endothelial growth factor (VEGF) levels were in experimental groups measured compared to control. The averages of group spirulina were 81.31 (10 mg/100 gram BW), 65.99 (20 mg/100 gram BW), and 49.62 (40 mg/100 gram BW). In comparison with control group (62.70), VEGF level in group administered by spirulina dose of 20 mg/100 gram BW were close to control group.

Interleukin-6 (IL-6) Level as an Indikator of Progresivity Rheumatoid Arthritis (RA) Disease Putu Oky Ari Tania; Dorta Simamora; Wahyuni Dyah Parmasari; Febtarini Rahmawati
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 3, No 1 (2014): Edisi Maret 2014
Publisher : Universitas Wijaya Kusuma Surabaya

Rheumatoid Arthritis (RA) is autoimmune disease that attacks joints and synovial tissues. Rheumatoid Arthritis is characterized by inflammation that involves production of cytokines such as Interleukin 6 (IL-6). Increasing of interleukin 6 has correlation with activity and progressivity of the disease. This research was designed to know whether IL- 6 could be used as indicator progressivity of RA. The method that used for measuring IL-6 level is ELISA (Enzyme Linked Immunosorbent Assay), using the principle antigen-antibody binding. In early stage there were 9 persons (S01, S02, S03, S04, S07, S08, S09, S10 and S14) with of IL-6 level (mean : 3.640 pg/mL), intermediate stage there were 3 persons (S06, S13 and S15) with IL-6 level (mean : 12.453 pg/mL), late stage : 3 persons (S05, S11 and S12) with IL-6 level (mean : 59.349 pg/mL).

Giant Congenital Melanocytic Nevi (GCMN): Sebuah Laporan Kasus Langka Erico Lemuel Yonathan; Hari Darmawan
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 10, No 1 (2021): MARET 2021
Publisher : Universitas Wijaya Kusuma Surabaya

Giant Congenital Melanocytic Nevi (GCMN) is a nevus which present at birth or arise within the first few weeks of life. Incidence of GCMN is estimated at below 1:20.000 newborns. Lesion of GCMN usually appears with a black or brownish plaque and may have abnormal borders, flat or protruding surface and hypertrichosis. Giant Congenital Melanocytic Nevi (GCMN) is associated with malignant melanoma and neurocutaneous melanocytosis. A male newborn baby is reported to have a giant black hairy plaque, with irregular shape in his head since born. Patient was born naturally, full term, and normal birth weight. The mother has no medication consumption and disease history during pregnancy. In our three years follow up, there are multiple black patches with smaller size in front right and left leg, and the back of the body. The GCMN treatment consists of surgical and non-surgical procedures, psychological support, and lifelong monitoring. In this case, further examination and observation are needed.

THE EFFECT OF CLIMATE ON DEVELOPMENT VARIABILTAS Water-borne diseases Sudarso Sudarso
Jurnal Ilmiah Kedokteran Wijaya Kusuma 2009: edisi khusus Desember 2009
Publisher : Universitas Wijaya Kusuma Surabaya

Global warming issue in 21 century this become especial issue. The effect of global warming besides at another phenomenon, like floods, erosion, dryness, increasing temperature of earth, climate change and also its influence to human being, especially for health. Climate change is expected to have considerablke impact on health, and one of the most important is waterborne diseases. Weather influences the transport and dissemination of the microbial agents via rainfall and runoff and survival and/or growth such factors as temperature. Knowledge about transport processes and fate of microbial pollutants associated with rainfall and snowmelt is key to predicting risk from change in weather variability. Water-borne diseases can be infected by many routes of exposure, as well as individual or population susceptibility, to waterborne pathogens, with water quality, avaibility, sanitation, and hygiene all playing a role.More than 100 types of pathogenic bacteria, viruses, and prozoa can be found in contaminated water.

The Corelation of Exclusive Breastfeeding with Nutritional Status in Babies Age 6-24 Months at the Kedungsari Health Center, Mojokerto Regency sukma sahadewa; Nike Salindri; Sandra Miladyna; Siti Hadijah
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 10, No 2 (2021): SEPTEMBER 2021
Publisher : Universitas Wijaya Kusuma Surabaya

The objectives of this research is to find out the prevalence of exclusive breastfeeding, nutritional status, and the correlation between of breastfeeding and nutritional status in babies aged 6 to 24 months at the Kedungsari Public Health Center in Mojokerto Regency. This study used 50 babies aged 6-24 months from the Kedungsari Health Center as samples. This study applied a cross-sectional study design. The data was collected by gathering primary data via questionnaires and secondary data from the Kedungsari Health Center. The majority of the children in this research, aged 6-24 months, had been exclusively breastfed (58%). The majority of the children in this research, aged 6 to 24 months, showed normal nutritional status (74%). Furthermore, in the Kedungsari Health Center in Mojokerto Regency, there is a correlation between of breastfeeding and nutritional health in infants aged 6 to 24 months. This study's findings provide up-to-date information on the prevalence of exclusive breastfeeding, nutritional status, and the correlation between exclusive breastfeeding and nutritional status in babies aged 6 to 24 months.

Efek Pemberian Ekstrak Daun Pegagan (Centella Asiatica) Terhadap Penyembuhan Luka Sayat Pada Tikus Putih Jantan (Rattus Norvegicus) Galur Wistar I Made Subhawa Harsa
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 9, No 1 (2020): MARET 2020 available online since April 2020
Publisher : Universitas Wijaya Kusuma Surabaya

Wound refers to partly damage or loss of body tissue. One way that has been used by the people in helping the process of wound healing is the use of medicinal plants, such as gotu kola (Centella asiatica). Gotu kola (Centella asiatica) is kind of plant that found almost in all territories of Indonesia which functions as a cell revitalizing substance which quickens wound healing those are burnt, skin ulcer and to prevent keloid. This study is aimed to know the effect of giving gotu kola leaf extract (Centella Asiatica) against to the healing of the wound incision on male white rats (Rattus Norvegicus) wistar strain. This study is a pure experimental research using the randomized post test only control group design with the subjects are 30 male white rats (Rattus norvegicus) wistar strain that were divided into 3 groups, namely K1, K2, and K3. The incision wound were made on the back of all white rat in each group with a length of ± 2 cm and a depth of ± 2 mm. The wound in the negative control group (K1) was not given any substance; in the positive control group (K2) was given povidone iodine 10%; and in the treatment group (K3) was given gotu kola leaf extract at a dose of 37,5 mg/150 grBB. The study was done for 10 days. Furthermore, wound observation and monitoring is held. Then the results were processed by using One Way ANOVA. The result study of wound incision healing on male white rats (Rattus norvegicus) wistar strain shows that there is significant difference among the negative control group (K1), the positive control group (K2), and the treatment group (K3) on One Way ANOVA test which significant p-value are 0,027 (p < 0.05). The result of Post-Hoc LSD test also shows a significant differences among the K1 and K3 groups, and K2 and K3 groups which significant p-values are 0,011 and 0,038 (p < 0,05). From these results, it can be concluded that gotu kola leaf extract (Centella asiatica) effective on quickens wound healing of the wound incision on male white rats (Rattus norvegicus) wistar strain.

THE THREE OF DYES TO SEE METACROMATIC GRANULA Akhmad Sudibya
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 1, No 2 (2012): Edisi Oktober 2012
Publisher : Universitas Wijaya Kusuma Surabaya

There are two stains in addition to Neisser’s Stain to detect metachromatic granules. The two stains are Albert’s Diphtheria Stain and Loeffler’s Alkalin Methylene Blue Stain for Metachromatic Granules. They should be taught to medical students.

Page 18 of 39 | Total Record : 390

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Jawa timur

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