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Jurnal Ilmiah Kedokteran Wijaya Kusuma

JIKW
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Published by Universitas Wijaya Kusuma Surabaya

ISSN : 19782071 EISSN : 25805967 DOI : -

Core Subject : Health, Science,

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health

Jurnal Ilmiah Kedokteran Wijaya Kusuma (JIKW) is a periodically scientific publication that contains articles written in Indonesia or english. JIKW receive articles in the scope of Biomedical Sciences, degenerative diseases, infections, congenital abnormalities and public health. JIKW published twice a year. The articles will be published in JIKW only manuscript that has never be published or published in other journal. Writers who will publish the article please follow the JIKW guidelines. The entire management process both admission and review the article is done by online.

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Articles 390 Documents

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Hubungan Tingkat Activity Daily Living (ADL) dan Kualitas Hidup Lansia di Magetan Rinandha Yusfahreza Wildhan; Rivan Virlando Suryadinata; Ida Bagus Made Artadana
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 11, No 1 (2022): MARET 2022
Publisher : Universitas Wijaya Kusuma Surabaya

Most chronic diseases begin to appear in the elderly. Physiological decline in the elderly will also have an impact on the daily activities of the elderly. Dependence on other people is needed by most of the elderly in carrying out daily activities. This will directly affect the quality of life for the elderly. This study aims to analyze the relationship between the level of Activity Daily Living (ADL) and quality of life in the elderly group in Magetan. This research method is observational using a sample of 80 elderly people. Data were collected by purposive sampling in accordance with the inclusion and exclusion criteria in the study. The daily activity assessment process uses the Activity Daily Living (ADL) questionnaire, while the quality of life assessment also uses a questionnaire which is divided into four domains (physical, psychological, social and environmental). The research data obtained will be tested for correlation using the Spearman test. The results of the Spearman test analysis showed that there was a positive correlation between Activity Daily Living (ADL) on the four domains (physical, psychological, social and environmental) on quality of life (p<0.05). In the four domains, there was a relationship (correlation) with ADL, namely the physical domain (r=0.560), psychological domain (r=0.463), social domain (r=0.415), environmental domain (r=0.340). So it can be concluded that there is a relationship between Activity Daily Living (ADL) on the four domains, namely physical, psychological, social and environmental. However, the physical domain has the greatest influence on the daily activities of the elderly.

Pengaruh C-Phycocyanin Terhadap Kadar Soluble Glikoprotein (Sgp130) Pada Trofoblas Tikus Wistar Yang Dipapar Interleukin-6 (IL-6) Elizabeth Haryanti; Harry K Gondo
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 6, No 1 (2017): Edisi Maret 2017
Publisher : Universitas Wijaya Kusuma Surabaya

The placenta is a joint organ of the uterus surface mother and fetus. One of cytokines of the placenta is IL-6 which is essential for normal placental development and successful pregnancy. Sgp130 binds Interleukin-6-sIL-6R complex, so Interleukin-6 signal cannot be passed on. Both factors play an important role in pre-eclampsia which has high levels of IL-6 and sgp130. They are expected to be suppressed by administration of C-phycocyanin. The aim of this study to prove effect of C-phycocyanin on sgp130 levels among wistar rats’ trophoblasts exposed to IL-6. The design of the study was Experiment, Post Test Only Control, analyse with One way Anova. The samples were 25 rats divided four treatment groups. Dose of C-Phycocyanin (10mg, 20mg, 40mg). The results significant difference between control and treatment group IL-6, IL-6 + CPC10, IL-6 + CPC20. But there was no significant difference between control group and IL-6 + CPC40, sig value. 0.214 (sig. <0.05). Conclusion. There is an effect of C-Phycocyanin on Sgp130 levels in wistar rats’ trophoblasts exposed to IL-6 at a dose of C-Phycocyanin 40mg.

PENGARUH PEMBERIAN ROYAL JELLY PERORAL TERHADAP BERAT TESTIS DAN PROPORSI BERAT TESTIS TERHADAP BERAT BADAN TIKUS PUTIH (Rattus norvegicus strain Wistar) JANTAN Hardiyono Hardiyono; Ayly Soekamto
Jurnal Ilmiah Kedokteran Wijaya Kusuma No 1 (2011): Edisi Juli 2011
Publisher : Universitas Wijaya Kusuma Surabaya

Royal jelly dapat meningkatkan vitalitas dianggap manusia dan kesuburan. Penelitian terhadaphewan telah membuktikan bahwa royal jelly makan untuk ayam, burung puyuh dan kelinci dapatmeningkatkan kesuburan. Nurmiati studi (2002) juga membuktikan bahwa royal jelly dapat meningkatkankesuburan tikus betina. Penelitian ini adalah untuk membuktikan pengaruh royal jelly untukspermatogenesis dengan mengukur berat testis dan proporsi berat testis terhadap berat badan tikus padatikus putih jantanPenelitian ini merupakan penelitian eksperimental laboratorium dengan menggunakan TestPosting Hanya Kontrol Grup Desain murah maka data dianalisis statistik menggunakan Anova dengantingkat signifikansi kurang dari 0,05. Penelitian sampel 32 orang dewasa tikus putih jantan yang dibagimenjadi 4 kelompok secara acak, dan masing-masing kelompok dirawat selama 52 hari. K1: kelompokkontrol mendapatkan aquadest 3 ml / hari makan lisan, P1: kelompok perlakuan dengan makan jellykerajaan lisan 15 mg / kgBB / hari, P2: kelompok perlakuan dengan makan jelly kerajaan lisan 30 mg /kgBB / hari dan P3: kelompok perlakuan dengan makan royal jelly 45 mg lisan / kgBB / hari. Semuadata-data dianalisis menggunakan Anova menunjukkan perbedaan yang signifikan antara semuaperlakuan dan kelompok kontrol. Untuk mengidentifikasi kelompok mana yang memiliki perbedaan yangsignifikan dalam setiap variabel, analisis dilanjutkan dengan uji LSD.Kesimpulannya, makan royal jelly oral tidak berubah berat testis dan proporsi berat testisterhadap berat badan tikus pada tikus putih jantan

Efek Kadmium terhadap Kadar Glukosa Hepar Tikus Putih (Rattus norvegicus) in Vitro Eko Suhartono
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 7, No 2 (2018): Edisi September 2018
Publisher : Universitas Wijaya Kusuma Surabaya

Mekanisme kadmium menginduksi toksisitas pada hepar yaitu dengan menimbulkan stres oksidatif. Stres oksidatif menghambat enzim-enzim yang berperan dalam proses metabolisme glukosa. Penelitian ini bertujuan untuk menganalisis perbedaan kadar glukosa pada homogenat hepar. Penelitian ini merupakan penelitian eksperimental laboratorik yang dilakukan pada 4 kelompok: kelompok P0 yang tidak dipajankan Cd, kelompok P1 dipajankan Cd 0,03 mg/L, kelompok P2 dipajankan Cd 0,3 mg/L, dan kelompok P3 dipajankan Cd 3 mg/L. Hasil penelitian didapatkan rata-rata kadar glukosa pada kelompok P0 sebesar 21.667 μM, kelompok P1 sebesar 33.278 μM, kelompok P2 sebesar 69.889 μM, dankelompok P3 sebesar 150.667 μM. Melalui uji statistik Kruskal-Wallis didapatkan perbedaan yang bermakna p=0,000 (p<0,05) dan uji pos hoc Mann-Whitney juga menunjukkan perbedaan yang bermakna pada semua kelompok. Dapat disimpulkan bahwa semakin tinggi konsentrasi pemajanan Cd terhadap homogenat hepar maka semakin tinggi pula peningkatan kadar glukosa pada hepar tikus.

Pengaruh Pemberian Royal Jelly peroral terhadap jumlah sel-sel spermatosit primer, dan sel-sel spermatid pada testis tikus putih (rattus norvegicus strain Wistar) Jantan Ayly Soekanto
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 2, No 3 (2011): Volume Edisi Khusus Desember 2011
Publisher : Universitas Wijaya Kusuma Surabaya

Royal jelly dapat dianggap meningkatkan vitalitas dan kesuburan pria.

Relationship Between Medication Adherence Level and Recovery of Pulmonary Tuberculosis Patients at Gapura Public Health Center Sumenep Maulina Syafakamila; Rini Purbowati
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 11, No 2 (2022): SEPTEMBER 2022
Publisher : Universitas Wijaya Kusuma Surabaya

Pulmonary tuberculosis is an infectious disease caused by Mycobacterium tuberculosis (MTB). Regarding this, Indonesia is ranked second globally in terms of tuberculosis prevalence. TB cases in Sumenep Regency are increasing every year. The high incidence of TB in Sumenep mostly is caused by the patients' lack of adherence to taking medication. The level of compliance in taking drugs can be influenced by several factors including age, educational level, and gender. This study aimed to ascertain the association between medication adherence and recovery in patients with pulmonary tuberculosis at the Gapura Public Health Center Sumenep. This study employed an analytical observational design with a cross-sectional approach, utilizing secondary data from medical records and TB.01 treatment cards. The population in this study consisted of 40 individuals. Total sampling is used to choose samples. The study's findings revealed that most patients 62.5% were male, 37.5% were between the ages of 26-45, 15% were from Gapura Barat, 35% had an elementary school education, and 55% were farmers. As many as 90% of patients adhere to treatment and 87.5% recover. Additionally, statistical tests yielded a p-value of <0.001. The study concludes a correlation between medication adherence and recovery of patients with pulmonary tuberculosis at the Gapura Public Health Center Sumenep. It is advised that health personnel maintain as many programs as possible, including counseling, home visits, and remote monitoring via telecommunications.

Pengaruh Pemberian Ekstrak Kencur (Kaempferia galanga L.) terhadap Peningkatan Zona Hambat Pertumbuhan Bakteri Staphylococcus aureus Linda Putri Utami; Peter Gunawan Tandean; Liliawanti Liliawanti
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 9, No 2 (2020): SEPTEMBER 2020
Publisher : Universitas Wijaya Kusuma Surabaya

The prevalence of infectious diseases in Indonesia is still relatively high, for example Infection caused by Staphylococcus aureus. Indonesia has many traditional plants that can be used for herbal treatments containing tannins, flavonoids, and essential oils which have relatively high antibacterial activity by forming inhibitory zones in the Staphylococcus aureus bacteria which are the cause of skin infections food poisoning to systemic infections. Thereforekencur can be used as an alternative medicine. This study was intented to determine the effect of giving kencur extract (Kaempferia galanga L.) In inhibiting the growth of Staphylococcus aureus bacteria. This study was experimental laboratory used plate diffusion method of “Postest Ony Control Group Design” design. There were 7 groups, 5 treatment groups and 2 control groups. The concentration of treatment group was 100%, 50%, 25%, 12,5%, 6,25% while for positive control using amoxicillin 25μg and aquadest as negative control. The bacterial used were Staphylococcus aureus. The results showed that kencur extract (Kaempferia galanga L.) had an antibacterial effect in inhibiting the growth of Staphylococcus aureus bacteria.With a value of p = 0.001 or p <α. kencur extract (Kaempferia galanga L.) has an antibacterial effect in inhibiting the growth of Staphylococcus aureus bacteria.

LAPORAN KASUS : GAMBARAN SCINTIGRAFI PADA TIROIDITIS OTOIMUN ATROPIKANS Sianny Suryawati
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 1, No 2 (2012): Edisi Oktober 2012
Publisher : Universitas Wijaya Kusuma Surabaya

Tiroiditis otoimun dengan berbagai manifestasinya seringkali menyerupai kelainan tiroid lain. Pengukuran uptake tiroid dan gambaran scintigrafi, bersama dengan tes fungsi tiroid, berperan dalam membedakan tiroiditis otoimun dari penyakit tiroid lain, yang pada akhirnya menentukan terapi yang akan diberikan. Pengenalan akan spektrum hasil pemeriksaan scintigrafi pada kelainan ini akan memampukan radiolog membantu pada klinis dalam menentukan diagnosis.

HEALTH Atik Sriwulandari
Jurnal Ilmiah Kedokteran Wijaya Kusuma 2009: edisi khusus Desember 2009
Publisher : Universitas Wijaya Kusuma Surabaya

A healthy human is not only a sound body, but also spiritually healthy. So healthy and ideal body in terms of health aspects of physical, mental and social and not only free of disease (WHO Definition of Health 1950). All these aspects will affect the appearance or performance of each individual, in performing daily activities like work, work, be creative and do things that are productive and useful. Health, education and income of every individual are the three main factors which influence the quality of human resources. Therefore, every individual has the right and must always maintain good health, which is the main capital in order to live productive, happy and prosperous.

One Case Suspected Chronic Bullous Disease in Childhood Mellyanawati Mellyanawati
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 10, No 2 (2021): SEPTEMBER 2021
Publisher : Universitas Wijaya Kusuma Surabaya

Penyakit bula pada anak sangat beraneka ragam, mulai dari yang paling sering adalah impetigo bulosa dan epidermolysis bulosa. Sedangkan penyakit bulosa lain pada anak yang lebih jarang dijumpai adalah penyakit bulosa linear IgA pada anak, pemfigoid bulosa dan sistemik lupus eritematosus bulosa. Salah satu varian dari penyakit bulosa linear Ig A pada anak adalah Chronic bullous disease in childhood (CBDC) yaitu suatu penyakit autoimun yang jarang dijumpai dan muncul pada usia prepubertas. Ciri khas dari penyakit ini adalah timbulnya lepuh yang muncul secara mendadak dan biasanya lesi yang baru muncul di sekitar lesi yang mulai sembuh dengan membentuk pola lingkaran (clusters of jewels) dan seringnya pasien disertai dengan rasa gatal. Untuk diagnosa pasti dari penyakit ini adalah dengan melakukan biopsi dan pemeriksaan imunofloresen direk. Terapi utamanya sendiri yaitu dapson dan sulfapiridin, sedangkan prednison dengan dosis rendah sebagai terapi tambahan lini pertama. Tujuan dari laporan kasus ini adalah ingin mengetahui efikasi dan efek samping dari pemberian oral steroid pada kasus dengan lesi bula yang diduga CBDC. Seorang anak laki-laki berusia 5 bulan, suku Jawa, datang ke poliklinik kulit dan kelamin Rumah Sakit Kandou dengan keluhan adanya bercak kemerahan yang disertai lenting berisi cairan jernih di hampir seluruh tubuh sejak kurang lebih 1 bulan yang lalu. Diagnosis pasti pada pasien ini masih belum dapat diketahui , namun diduga penyakit bula pada anak CBDC, dikarenakan berdasarkan anamnesis dan pemeriksaan fisik saja, karena keterbatasan alat dan keluarga pasien menolak untuk dilakukan pemeriksaan penunjang. Terapi diberikan dengan tujuan agar keluhan dari pasien dapat berkurang dan dengan efek samping yang minimal. Pemberian prednison oral yang diberikan secara tapering-off, ditambah dengan oral antihistamin dan topikal antibiotik dan steroid memberikan hasil yang cukup signifikan pada pasien. Kesimpulan walaupun sebenarnya penyakit ini dapat sembuh sendiri dalam hitungan bulan, namun dengan pemberian oral steroid dan antihistamin dengan kombinasi obat topikal dapat mempercepat proses penyembuhan pada pasien.

Page 20 of 39 | Total Record : 390

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