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e-CliniC
Published by Universitas Sam Ratulangi
ISSN : 23375949     EISSN : -     DOI : -
Core Subject : Health,
Health Professions
Jurnal e-CliniC (eCl) diterbitkan oleh Perhimpunan Ahli Anatomi Indonesia bekerja sama dengan Fakultas Kedokteran Universitas Sam Ratulangi Manado. Jurnal ini diterbitkan 3 (tiga) kali setahun (Maret, Juli, dan November). Sejak tahun 2016 Jurnal e-CliniC diterbitkan 2 (dua) kali setahun (Juni dan Desember). Jurnal e-CliniC memuat artikel penelitian, telaah ilmiah, dan laporan kasus di bidang ilmu kedokteran klinik.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 1,074 Documents
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Long-Term Outcomes of Cataract Surgery: Analysis of Visual Acuity and Intraocular Pressure in a Tertiary Care Center Nursalim, Ade J.; Sumual, Vera; Chietra, Andrew; Emily, Ardelia; Rusli, Richardo
e-CliniC Vol. 12 No. 3 (2024): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v12i3.58044

Abstract

Abstract: Posterior capsule opacity (PCO) is a common complication following cataract surgery, caused by the proliferation of residual lens epithelial cells. This study aimed to evaluate the long-term effects of Nd:YAG laser capsulotomy on intraocular pressure (IOP) and visual acuity in PCO patients. This was a retrospective descriptive study. Samples were 24 patients diagnosed with PCO who underwent Nd:YAG laser capsulotomy at Prof. Dr. R. D. Kandou Hospital, Manado, from January 1, 2022, to January 1, 2024. The study recorded pre- and post-procedure IOP and best-corrected visual acuity (BCVA) data. Descriptive analysis, including paired t-tests, was used to assess changes in IOP and BCVA over an average follow-up period of 19.2 months. The results showed a statistically significant improvement in BCVA (p=0.000), with mean values improving from 0.72 to 0.27 LogMAR. A significant reduction in IOP was also observed (p=0.015), with long-term IOP remaining stable. A weak correlation was found between follow-up duration and IOP variation (p=0.02). In conclusion, Nd:YAG laser capsulotomy significantly improves visual acuity and stabilizes intraocular pressure in the long term for PCO patients, suggesting its effectiveness in managing post-cataract surgery complications. Keywords: posterior capsule opacity; Nd:YAG laser capsulotomy; intraocular pressure; visual acuity; cataract surgery    
Rasio Neutrofil Limfosit sebagai Prediktor Kejadian Kebocoran Anastomosis pada Pasien Kanker Kolorektal Panelewen, Jimmy; Tendean, Michael; Langi, Fima; Akmal, Nuzly Q.
e-CliniC Vol. 12 No. 3 (2024): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v12i3.58246

Abstract

Abstract: Anastomotic leakage is a serious complication following colorectal cancer resection that can increase morbidity and mortality. This study aimed to analyze the potential of the neutrophil-lymphocyte ratio (NLR) as a predictor of anastomotic leakage in colorectal cancer patients. This was a retrospective analytical and observational study involving 30 patients who underwent colorectal cancer resection and anastomosis at Prof. Dr. R. D. Kandou Hospital in Manado. The NLR values were analyzed preoperatively and on the first (D+1), third (D+3), fifth (D+5), and seventh (D+7) postoperative days. The results showed significant differences in NLR values between leakage and non-leakage groups across all phases (p<0.001). The receiver operating characteristic (ROC) curve analysis yielded optimal NLR cut-offs for leakage prediction: preoperative >2.1150, D+1 >3.4750, D+3 >2.7650, D+5 >3.0200, and D+7 >3.2850, with sensitivity and specificity reaching 100% in several phases. In conclusion, neutrophil-lymphocyte ratio has a potential as an accurate predictor of anastomotic leakage, enabling early detection and improved risk management. Further research with larger samples is needed to validate these findings and explore their clinical applications. Keywords: neutrophil-lymphocyte ratio; anastomotic leakage; colorectal cancer    Abstrak: Kebocoran anastomosis merupakan komplikasi serius pasca reseksi kanker kolorektal yang dapat meningkatkan morbiditas dan mortalitas. Penelitian ini bertujuan menganalisis potensi rasio neutrofil limfosit (RNL) sebagai prediktor kejadian kebocoran anastomosis pada pasien kanker kolorektal. Penelitian ini menggunakan metode observasional analitik retrospektif, melibatkan 30 pasien yang menjalani reseksi dan anastomosis kanker kolorektal di RSUP Prof. Dr. R. D. Kandou Manado. Nilai RNL dianalisis pada fase preoperatif, hari pertama (H+1), ketiga (H+3), kelima (H+5), dan ketujuh (H+7) pasca operasi. Hasil penelitian memperlihatkan perbedaan bermakna nilai RNL antara kelompok kebocoran dan tanpa kebocoran pada semua fase (p<0,001). Analisis kurva ROC menghasilkan cut-off optimal RNL untuk prediksi kebocoran: preoperatif >2,1150, H+1 >3,4750, H+3 >2,7650, H+5 >3,0200, dan H+7 >3,2850, dengan sensitivitas dan spesifisitas mencapai 100% pada beberapa fase. Simpulan penelitian ini ialah rasio neutrofil limfosit memiliki potensi sebagai prediktor yang akurat untuk kebocoran anastomosis, serta memungkinkan deteksi dini dan manajemen risiko yang lebih baik. Penelitian lebih lanjut dengan sampel yang lebih besar diperlukan untuk memvalidasi temuan ini dan mengeksplorasi aplikasi klinisnya. Kata kunci: rasio neutrofil limfosit; kebocoran anastomosis; kanker kolorektal
Pengaruh Intervensi Pill Box terhadap Kepatuhan Minum Obat dan Luaran Klinis pada Pasien Lanjut Usia dengan Penyakit Hipertensi Mpila, Deby A.; Wiyono, Weny I.; Citraningtyas, Gayatri
e-CliniC Vol. 12 No. 3 (2024): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v12i3.58383

Abstract

Abstract: The prevalence of hypertension increases with age. One of the keys to effective hypertension therapy is adherence. There are several ways to improve medication adherence, one of which is by using pill boxes. This study aimed to determine the effect of pill box intervention on the level of medication adherence and clinical outcomes among geriatric patients with hypertension at the Imanuel Clinic Manado. This was an experimental analytical study with randomized controlled trial (RCT) using pre-test and post-test control group design. Data were obtained prospectively in the period of July to August 2024 with a sample size of 60 respondents (30 intervention and 30 control). The level of adherence was assessed using MMAS-8 questionnaire and data of clinical outcomes were obtained from systolic and diastolic blood pressures. The measurement was preceded before and after treatment. The data were analyzed statistically using bivariate analysis. A p-value of <0.05 was considered statistically significant. The result showed that the pill box intervention had a significant effect on the level of medication adherence (p=0.001). Meanwhile, there was no effect of pill box intervention on clinical outcomes (p=1.000) because as many as 60 patients (100%) had reached the target blood pressure before and after treatment. In conclusion, using pill box can increase medication adherence in geriatric patients with hypertensive disease. Keywords: geriatric patients; hypertension; pill box; medication adherence; clinical outcome    Abstrak: Prevalensi hipertensi semakin meningkat seiring bertambahnya usia. Salah satu kunci keberhasilan terapi hipertensi ialah kepatuhan. Terdapat beberapa cara meningkatkan kepatuhan minum obat, salah satunya dengan menggunakan pill box. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian intervensi pill box terhadap tingkat kepatuhan minum obat dan luaran klinis pada pasien lanjut usia (lansia) dengan penyakit hipertensi di Klinik Imanuel Manado. Penelitian bersifat analitik eksperimental dengan jenis penelitian randomized controlled trial (RCT) dengan desain pre-test dan post-test control group. Data diperoleh secara prospektif pada periode Juni–Agustus 2024 dengan jumlah sampel sebanyak 60 pasien (30 pasien intervensi dan 30 pasien kontrol). Kepatuhan minum obat diukur menggunakan kuesioner MMAS-8 dan luaran klinis diukur berdasarkan tekanan darah sistolik dan diastolik. Pengukuran dilakukan sebelum dan setelah perlakuan. Data dianalisis secara statistik menggunakan analisis bivariat. Nilai p<0,05 dianggap bermakna secara statistik. Hasil penelitian menunjukkan bahwa intervensi pill box memberikan pengaruh bermakna terhadap kepatuhan minum obat (p=0,001). Tidak terdapat pengaruh intervensi pill box terhadap luaran klinis (p=1,000), karena sebanyak 60 pasien (100%) telah mencapai target tekanan darah baik sebelum mapun sesudah perlakuan. Simpulan penelitian ialah penggunaan pill box dapat meningkatkan kepatuhan pasien lanjut usia untuk mengonsumsi obat antihipertensi. Kata kunci: lanjut usia; hipertensi; pill box; kepatuhan minum obat; luaran klinis
Cost of Illness Pasien Hipertensi Rawat Inap di RSUP Prof. Dr. R. D. Kandou Manado Lolo, Widya A.; Wiyono, Weny I.; Mpila, Deby A.
e-CliniC Vol. 12 No. 3 (2024): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v12i3.58444

Abstract

Abstract: Besides causing systemic damage to organs, hypertensive disease also has an impact on the health economy sector (double burden disease). This study aimed to determine the cost of illness of hypertensive inpatients and its suitability with INA-CBG's tariff. This was an analytical and observational study with a cross-sectional designh. Data were collected retrospectively from the medical records of hypertensive inpatients registered as members of Jaminan kesehatan Nasional (National Health Insurance) from January to June 2024 and from financial department of Prof. Dr. R. D. Kandou Hospital Manado. Pharmaeconomic analysis was used based on hospital perspective and prevalence approach. The data were analyzed using one sample t-test to compare the congruence between cost of illness and INA-CBG’s tariff. There were 30 inpatients in this study, consisting of 10 males and 21 females. The results showed that the difference between total cost of illness and INA-CBG’s tariff was Rp.76,403,811. The one sample t-test showed that the congruence between cost of illness and INA-CBG’s tariff was significantly different based on the p-values of each code, as follows: 0.001 (I-17-14-I), 0.000 (I-17-14-II), and 0.000 (I-17-14-III). In conclusion, the total cost of illness of hypertensive inpatients at Prof. Dr. R. D. Kandou Hospital was Rp. 251,287,311 with an average per patient of Rp. 8,376,244. Moreover, overall there is a significant difference between cost of illness and INA-CBG's tariff. Keywords: cost of illness; hypertensive inpatients; Indonesian Case-based Group    Abstrak: Penyakit hipertensi bukan hanya menyebabkan kerusakan sistemik di organ namun juga berdampak pada sektor ekonomi kesehatan (double burden disease). Penelitian ini bertujuan untuk mengetahui besaran terapi pasien hipertensi (cost of illness) dan kesesuaiannya dengan tarif INA-CBG’s. Jenis penelitian ialah observasional analitik dengan desain potong lintang. Data pasien hipertensi Jaminan kesehatan Nasional (JKN) rawat inap diperoleh secara retrospektif dari Bagian Rekam Medik dan Bagian Keuangan RSUP Prof. Dr. R. D. Kandou Manado periode Januari-Juni 2024. Analisis farmakoekonomi dilakukan dengan kajian berdasarkan perspektif rumah sakit dimana kategori biaya dalam perhitungan cost of illness menggunanakan biaya medis langsung dengan pendekatan secara prevalensi. Data analisis uji beda menggunakan one sample t-test untuk mengetahui perbandingan biaya cost of illness dengan tarif INA-CBG’s. Hasil penelitian mendapatkan 30 pasien sebagai sampel, terdiri dari 10 laki-laki dan 21 perempuan. Besaran selisih antara cost of illness dengan tarif INA-CBG’s sebesar Rp. 76.403.811. Kesesuaian antara cost of illness dengan tarif INA-CBG’s menggunakan one sample t-test berbeda bermakna dengan nilai p masing-masing kode ialah 0,001 (I-17-14-I); 0,000 (I-17-14-II); dan 0,000 (I-17-14-III). Simpulan penelitian ini ialah total cost of illness pasien hipertensi rawat inap RSUP Prof Dr. R. D. Kandou sebesar Rp. 251.287.311 dengan rerata per pasien sebesar Rp. 8.376.244. Terdapat perbedaan bermakna antara cost of illness dan tarif INA-CBG’s. Kata kunci: cost of illness; pasien hipertensi; Indonesian Case-based Group
Profil Penggunaan Antibiotik dengan Metode Defined Daily Dose pada Pasien Pneumonia Rawat Inap Salah Satu Rumah Sakit Swasta Tipe C di Minahasa Clara, Santi; Nangoy, Edward; Posangi, Jimmy
e-CliniC Vol. 12 No. 3 (2024): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v12i3.58563

Abstract

Abstract: The high prevalence of pneumonia cases in Indonesia affects the increasing use of antibiotics, which can lead to resistance. The defined daily dose (DDD) method can be utilized to improve the quality of antibiotic use by enabling quantitative evaluation. This study aimed to determine the quantity of antibiotic use in pneumonia inpatients at type C private hospital in Minahasa from July 2022 to June 2023. This was a descriptive and retrospective study using secondary data of medical records of pneumonia inpatients that were calculated using the DDD method. The results obtained 45 pneumonia patients received antibiotic therapy. The highest usage antibiotic was ceftriaxone with 46.09 DDD/100 bed days. In conclusion, the administration of antibiotics for treatment was appropriate, however, there is a need to develop clinical pathway to provide a structured guidelines for patient management. Keywords: antibiotics; pneumonia; defined daily dose   Abstrak: Tingginya kasus pneumonia di Indonesia memengaruhi peningkatan penggunaan antibiotik yang dapat menyebabkan kejadian resistensi. Metode defined daily dose (DDD) dapat digunakan untuk meningkatkan kualitas penggunaan antibiotik yakni dengan melakukan evaluasi secara kuantitatif. Penelitian ini bertujuan untuk mengetahui kuantitas penggunaan antibiotik pada pasien pneumonia rawat inap salah satu rumah sakit swasta Tipe C di Minahasa periode Juli 2022 - Juni 2023. Jenis penelitian ialah deskriptif dengan pendekatan retrospektif menggunakan data sekunder berupa rekam medis pasien yang selanjutnya dihitung dengan menggunakan metode DDD. Hasil penelitian mendapatkan 45 pasien pneumonia yang menerima terapi antibiotik. Antibiotik dengan jumlah penggunaan tertinggi yakni ceftriaxone dengan nilai sebesar 46,09 DDD/100 bed days. Simpulan penelitian ini ialah secara keseluruhan pemberian antibiotik dalam pengobatan sesuai, namun perlu dilakukan pembuatan clinical pathway agar penanganan bagi setiap pasien dapat memiliki panduan yang terstruktur. Kata kunci: antibiotik; pneumonia; defined daily dose
Hubungan Kepatuhan Penggunaan Obat Antihipertensi dengan Kualitas Hidup Pasien Hipertensi Wagiu, Ariel E.; Wiyono, Weny I.; Mpila, Deby A.
e-CliniC Vol. 13 No. 1 (2025): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v13i1.58790

Abstract

Abstract: Hypertension is a condition where systolic and diastolic blood pressure exceeds values of 140 mmHg and 90 mmHg, respectively. Patient compliance related to the use of antihypertensive drugs is a major factor in improving the quality of life of hypertensive patients. This study aimed to determine the relationship between the level of compliance in consumption of antihypertensive drugs and the quality of life of hypertensive patients at Puskesmas Kawangkoan (public health center). This was an observational and analytical study with a cross-sectional approach. A total of 80 patients as samples were obtained using purposive sampling technique. Data on the level of compliance with drug use were obtained from the Morisky Medication Adherence Scale (MMAS-8) questionnaire and the Short-Form 36 (SF 36) questionnaire to measure quality of life in hypertensive patients. The results obtained 80 patients as samples. Data were statistically analyzed using the Spearman-rho test which showed a significant relationship between the level of compliance in drug consumption and the quality of life of hypertensive patients at Puskesmas Kawangkoan (p=0.000<0.05). In conclusion, there is a significant relationship between the level of compliance in antihypertensive drug consumption and the quality of life of hypertensive patients at Puskesmas Kawangkoan. Keywords: hypertension; medication adherence; quality of life.   Abstrak: Hipertensi adalah keadaan dimana tekanan darah sistolik dan diastolik melebihi nilai  140 mmHg dan 90 mmHg. Kepatuhan pasien dalam penggunaan obat antihipertensi merupakan faktor utama dalam peningkatan kualitas hidup pasien. Penelitian ini bertujuan untuk mengetahui hubungan tingkat kepatuhan penggunaan obat antihipertensi dengan kualitas hidup pasien hipertensi di Puskesmas Kawangkoan. Jenis penelitian ialah analitik observasional dengan desain potong lintang. Sampel penelitian diperoleh dengan teknik purposive sampling. Data tingkat kepatuhan penggunaan obat diperoleh dari kuesioner Morisky Medication Adherence Scale (MMAS-8) dan kuesioner Short-Form 36 (SF 36) untuk mengukur kualitas hidup pada pasien hipertensi. Hasil penelitian mendapatkan sebanyak 80 pasien sebagai sampel. Hasil uji Spearman-rho menunjukkan adanya hubungan bermakna antara tingkat kepatuhan penggunaan obat dengan kualitas hidup pasien hipertensi (p=0,000<0,05). Simpulan penelitian ini ialah terdapat hubungan bermakna antara tingkat kepatuhan penggunaan obat antihipertensi dengan kualitas hidup pasien hipertensi di Puskesmas Kawangkoan. Kata kunci: hipertensi; kepatuhan penggunaan obat; kualitas hidup
Neoadjuvant Lenvatinib in Advanced Unresectable Thyroid Carcinoma: Case Series and Literature Review Albert, Albert; Manginstar, Christian O.; Saleh, Denny; Merung, Marselus A.
e-CliniC Vol. 13 No. 1 (2025): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v13i1.58793

Abstract

Abstract: Lenvatinib, a tyrosine kinase inhibitor (TKI), has shown potential as a neoadjuvant therapy for inoperable thyroid cancer (TC). In this case series, we present three patients with unresectable thyroid tumors who responded favorably to lenvatinib treatment. A 60-year-old male with papillary thyroid cancer (PTC) experienced a 60% tumor volume reduction after five months of therapy. A 61-year-old male with medullary thyroid cancer (MTC) saw a 99% reduction after four months of lenvatinib and decrease of serum calcitonin and no residual disease six months after surgery. Lastly, a 67-year-old female with anaplastic thyroid cancer (ATC) showed a 70% tumor reduction and significant symptomatic relief. These cases highlight lenvatinib’s efficacy in reducing tumor size and stabilizing disease, improving surgical outcomes in patients initially deemed inoperable due to locally advanced tumors. Lenvatinib’s antitumor effects, driven by its antiangiogenic properties, suggest its potential as a valuable neoadjuvant treatment option in advanced thyroid cancer. Keywords: thyroid carcinoma; lenvatinib; case series
First Endoscopic-Guided Percutaneous Nephrolithotomy (ePSL) with Prone Split-Leg Position in Manado Phoebus, Andrien; Astram, Ari; Toreh, Christof; Arianto, Eko; Wihono, Frendy
e-CliniC Vol. 13 No. 1 (2025): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v13i1.59320

Abstract

Abstract: Literature has not yet defined the best position for percutaneous nephrolithotomy (PCNL) based on the complexity of the stone burden. This case of left-sided complex kidney stones underwent endoscopic-guided PCNL in an PSL (prone split-leg position). A 61-year-old woman with a chief complaint of right pelvic pain. Standard prone PCNL was planned for this patient, however, due to so much debris in the pelviocalyceal system during URS evaluation and ureter catheter insertion, we decided to puncture with ultrasound guidance rather than fluoroscopy. Intraoperatively there was residual superior calyx stone that was beyond the reach of nephroscope. We decided not to do a double puncture because of poor vision due to the floating debris. In the second procedure, the ePSL method was utilized. A C-arm and nephroscope examination revealed no active bleeding, no infundibulum laceration, and no remaining stones. The primary goals of this method were to remove stones from the urinary tract throughout the entire tract using a one-step, one-access procedure that made the most of the full range of endourologic equipment. There were a number of reasons why the prone split-leg position was chosen, including operator preference, familiarity with the position, and the inability to make a direct puncture in the upper pole. The main drawback was that patient would not be able to see how well and safely this method worked over time. In conclusion, complex kidney stones can be treated with ePSL performed in the prone split-leg position, which is a safe procedure with a low risk of complications. Keywords: percutaneous nephrolithotomy; prone split-leg position; complex kidney stones
Kekerasan dalam Rumah Tangga (KDRT) yang Terjadi di Kota Bitung Adam, Rahmat S.; Mallo, Nola T. S.; Tomuka, Djemi
e-CliniC Vol. 12 No. 3 (2024): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v12i3.59408

Abstract

Abstract: According to the Ministry of Women's Empowerment and Child Protection (PPPA) through the Online Information System for the Protection of Women and Children (SIMFONI PPA), in North Sulawesi 2023, the most dominant violence based on the location of the incidence is household.  Bitung is the area with the second highest number of domestic violence cases in 2023. This study aimed to obtain the description of domestic violence cases in Bitung 2022. This was a retrospective and descriptive study using secondary data taken from the Women's Empowerment and Child Protection Service and Police Department in Bitung. The relationships between variables were analayzed with the chi-square test. The results showed that the majority of victims were children (74.5%) with the type of penance violence (45.8%). Most often the perpetrator was the father (38.2%). The chi-square test  obtained p=0.008 for the relationship between victim and all types of violence; p=0,000 for the relationship between the relation of perpetrator and victim  and all types of violence; and p=0.542 for the relationship between location and all types of violence. In conclusion, the majority of domestic violence in Bitung is penance violence with children as the victims, and the father as perpetrator. There is no relationship between location and all types of violence. Keywords: types of violence; domestic violence; victim   Abstrak: Kementerian Pemberdayaan Perempuan dan Perlindungan Anak (PPPA) melalui Sistem Informasi Online Perlindungan Perempuan dan Anak (SIMFONI PPA) melaporkan  bahwa di Sulawesi Utara pada korban kekerasan per tahun 2023 yang paling mendominasi berdasarkan tempat kejadian ialah rumah tangga. Kota Bitung merupakan daerah dengan posisi ke-2 kasus kekerasan per tahun 2023. Penelitian ini bertujuan untuk menganalisis kasus KDRT di Kota Bitung. Jenis penelitian ialah deskrptif restrospektif dengan menggunakan data sekunder diambil dari Dinas Pemberdayaan Perempuan dan Perlindungan Anak Kota Bitung serta Polisi Resort Kota Bitung tahun 2022. Uji statistik terhadap hubungan variabel menggunakan uji chi-square. Hasil penelitian mendapatkan bahwa mayoritas korban ialah kategori anak (74,5%) dengan jenis kekerasan penelantaran (45,8%) serta pelaku paling banyak ialah ayah (38,2%). Hasil uji chi-square mendapatkan nilai p=0,008 pada variabel korban dengan semua jenis kekerasan; p=0,000 pada variabel hubungan pelaku dengan korban terhadap semua jenis kekerasan; dan p=0,542 pada hubungan antara variabel kecamatan dengan semua jenis kekerasan. Simpulan penelitian ini ialah mayoritas kekerasan dalam rumah tangga yang terjadi di Kota Bitung ialah penelantaran dengan korban terbanyak ialah anak, pelaku yang berstatus ayah, namun hubungan wilayah kejadian dari setiap kasus tidak berkontribusi dalam terjadinya kekerasan dalam rumah tangga. Kata kunci: jenis kekerasan; kekerasan dalam rumah tangga; korban
Faktor Risiko Terjadinya Enterokolitis Nekrotikan pada Neonatus Palinggi, Eoudia S.; Manoppo, Jeanette I. Ch.; Rompis, Johnny L.
e-CliniC Vol. 13 No. 1 (2025): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v13i1.59445

Abstract

Abstract: Necrotizing enterocolitis is inflammation of babies' digestive tract and the main cause of morbidity and mortality of premature neonates in the NICU. The exact etiology of necrotizing enterocolitis is not known so far. This study aimed to determine prematurity, formula feeding, sepsis, anemia, congenital heart disease and preeclampsia/eclampsia in mothers as risk factors for necrotizing enterocolitis in neonates and other risk factors that influence the incidence of necrotizing enterocolitis. This was a quantitative and analytical study with a cross sectional design. Sampling techniques were total sampling of necrotizing enterocolitis cases (38 patients) and executive sampling for control cases (38 patients) admitted to Prof. Dr. R. D. Kandou Hospital Manado using data of medical records. The results of the distribution table analysis and chi-square test showed that the risk factors analyzed that had p<0.05, namely prematurity (p<0.001), and sepsis (p<0.001). Other variables did not have significant relationships with the incidence of necrotizing enterocolitis (p>0.05), as follows: formula milk consumption (p>0.387), anemia (p>0.234), congenital heart disease (p>0.556), and mothers with preeclampsia/ eclampsia (p>0.556). In conclusion, prematurity and sepsis are risk factors for necrotizing enterocolitis in neonates at Prof. Dr. R. D. Kandou General Hospital, Manado. Keywords: risk factors; necrotizing enterocolitis; neonates   Abstrak: Enterokolitis nekrotikan (EKN) merupakan peradangan pada usus saluran cerna bayi yang menjadi penyebab utama morbiditas dan mortalitas neonatus prematur di NICU. Tingkat kematian EKN makin tinggi pada bayi yang lebih kecil. Sampai saat ini etiologi yang jelas mengenai EKN belum diketahui secara pasti. Penelitian ini bertujuan untuk mengetahui prematur, pemberian susu formula, sepsis, anemia, penyakit jantung bawaan, dan preeklamsi/eklamsi pada ibu sebagai faktor risiko terjadinya EKN pada neonatus, dan mengetahui faktor risiko lain yang memengaruhi kejadian EKN. Jenis penelitian ialah analitik kuantitatif dengan desain potong lintang. Teknik sampling penelitian ialah total sampling pada kasus EKN 38 pasien  dan executive sampling pada kontrol EKN 38 pasien yang dirawat di RSUP Prof. Dr. R. D. Kandou Manado melalui sumber data rekam medis. Hasil analisis tabel distribusi dan uji chi-square menunjukkan bahwa faktor risiko yang dianalisis mempunyai p<0,05 ialah faktor prematur (p<0,001), dan sepsis (p<0,001). Variabel lainnya tidak hubungan bermakna dengan kejadian EKN dengan nilai p>0,05 sebagai berikut:  pemberian susu formula (p>0,387), anemia (p>0,234), penyakit jantung bawaan (p>0,556), dan preeklamsi/eklamsi pada ibu (p>0,556). Simpulan penelitian ini ialah prematur dan sepsis merupakan faktor risiko terjadinya enterokolitis nekrotikan pada neonatus di RSUP Prof. Dr. R. D. Kandou Manado. Kata kunci: faktor risiko; enterokolitis nekrotikan; neonatus

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