Garuda - Garba Rujukan Digital

Article Per Year (5 Year)

All

Jurnal Fitofarmaka Indonesia

fitofarmakaindo
Website

Published by Universitas Muslim Indonesia

ISSN : 23560398 EISSN : 25412329 DOI : -

Core Subject : Health, Science,

Biochemistry, Genetics & Molecular Biology Chemistry Medicine & Pharmacology

Jurnal Fitofarmaka Indonesia merupakan salah satu jurnal yang dikelola oleh Laboratorium Farmakognosi-Fitomikia Fakultas Farmasi Universitas Muslim Indonesia yang terbit pertama kali pada bulan Januari 2014. Jurnal Fitofarmaka Indonesia merupakan jurnal ilmiah yang terbit secara on-line dan cetakan serta menerbitkan artikel atau karya ilmiah hasil penelitian dalam bidang obat bahan alam.

Arjuna Subject : -

Articles 150 Documents

3 4 5 6 7

UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAUN TOMAT BUAH (Lycopersicon esculentum Mill, var. pyriforme Alef) DAN DAUN TOMAT SAYUR (Lycopersicon esculentum Mill, var. commune Bailey) DENGAN METODE DPPH (1,1-Diphenyl-2-Picryl Hydrazil) Mamat Pratama; Muzakkir Baits; Rizky Nurul Yaqin
Jurnal Fitofarmaka Indonesia Vol 2, No 1 (2015): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Antioxidant are chemical compounds that can donate one or more electrons to free radicals, so that the free radical reaction is inhibited. Generally, the compounds that have potential as an antioxidant are flavonoids, phenolics and alkaloids. Leaves of tomato (Lycopersicon esculentum Mill.) are plants that contain alkaloid. This study aims to determine the antioxidant activity of the ethanol extract of leaves of fruit tomato (Lycopersicon esculentum Mill, var. pyriforme Alef.) and leaves of vegetable tomato (Lycopersicon esculentum Mill, var. commune Bailey.) with DPPH method (1,1-Diphenyl-2-Picryl Hydrazil). Ethanol extract is obtained by extracting the leaves of friut tomato powder (Lycopersicon esculentum Mill, var. pyriforme Alef.) and the leaves of vegetable tomato (Lycopersicon esculentum Mill, var. commune Bailey.) with maceration. Antioxidant activity was measured using a UV-Vis spectrophotometer with maximum absorption wavelength is 514 nm. Readable absorbance is used to calculate % inhibition and IC50. The results showed that the samples of the leaves of fruit tomato (Lycopersicon esculentum Mill, var. pyriforme Alef.) and leaves of vegetable tomato (Lycopersicon esculentum Mill, var. commune Bailey.) have antioxidant activity with IC50 values of each of 279.482 µg/mL and 280.190 µg/mL. This shows the ethanol extract of leaves of fruit tomato (Lycopersicon esculentum Mill, var. pyriforme Alef.) and leaves of vegetable tomato (Lycopersicon esculentum Mill, var. commune Bailey.) has a very weak activity as an antioxidant.

SKRINING FITOKIMIA EKSTRAK JAMUR KANCING (Agaricus bisporus) Asriani Suhaenah; Siska Nuryanti
Jurnal Fitofarmaka Indonesia Vol 4, No 1 (2017): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

The phytochemical screenings and analysis of chemical compounds in n-hexan extract, ethyl acetat extract and ethanol extract, of Agaricus bisporus with Thin Layer Chromatography (TLC) has been carried out. Extraction process was performed with terraced maceration, identification of bioactive compound with thin layer chromatography. The result of Thin Layer Chromatography test showed that n-hexane extract contains flavonoid, coumarin, therpenoid and steroid. Ethyl acetate extract contains flavonoid, coumarine, therpenoid. Ethanol extract contains flavonoid, alkaloid, polyphenol, coumarin, terpenoid.

ANALISIS KANDUNGAN VITAMIN C DAN β- KAROTEN DALAM DAUN KELOR (Moringa oleifra Lam.) DENGAN METODE SPEKTROFOTOMETRI UV–VIS Masdiana Tahir; Nurul Hikmah; Rahmawati Rahmawati
Jurnal Fitofarmaka Indonesia Vol 3, No 1 (2016): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

This research aimed to analyze the levels of vitamin C and β-carotene in Moringa leaves extract (Moringa oleifera Lam.) using UV-Vis spectrophotometry. Vitamin C on Moringa leaves are extracted with ethanol 96%. The extracts obtained was qualitatively analyzed of levels of vitamin C using specific reagents an iodine 1% and ammonium molybdate 5%. Than quantitatively using UV-Vis spectrophotometry at wavelength of 570 nm, obtained an verage grade of 7,96 mg/g. For β-carotene, Moringa leaves were extracted with acetone. The extract obtained was extracted again with ether, then saponified with KHO solvent 15% w/v in methanol, allowed to stand overnight. The extract obtained was extracted again with ether, then freed from wet with distilled water. Extracts were analyzed qualitatively using thin layer chromatography and quantitatively using UV-Vis spectrophotometry at wavelength of 450 nm and obtained an average grade of 3,31 mg/g.

ISOLASI DAN IDENTIFIKASI GOLONGAN KIMIA AKTIF ANTIOKSIDAN EKSTRAK ETANOL DAUN JAMBU METE (Anacardium occidentale L.) A Amaliah Dahlia; Hasnawati Hasnawati
Jurnal Fitofarmaka Indonesia Vol 1, No 1 (2014): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Has been carried out isolation and identification of active chemical groups ethanol extract antioxidant Cashew Leaves (Anacardium occidentale L.) in aims is determine the class of the active antioxidant compounds from ethanol extract of Cashew Leaves (Anacardium occidentale L.). Sample of 400 grams of macerated with ethanol produces dry extract 20.087 grams. Dry done profile TLC plate and then eluted with eluent n-hexane: ethyl acetate (6:4), and then sprayed DPPH to determine antioxidant compounds. Ethanol extracts was than isolated using vacum liquid chromatography column with n-exane, eluent ratio of n-hexane: ethyl acetate (9:1,8:2,7:3, 6:4, 5:5, 4:6, 3: 7, 2:8, 1:9) and ethyl acetate. XI fractions obtained, then sprayed with DPPH fraction VI showed the most intense antioxidant activity. Results isolates obtained were then identified using uv-vis spectroscopy showed maximum absorption at a wavelength of 424.50 nm, Infrared spectroscopy showed absorbance at wave number 3393.18 cm-1 shows possibility the O-H group reinforced the wave number 1102.20 which indicates the possibility of a C-O group, te wave number 2923,44 cm-1 shows possibility the C-H (aromatic), the wave number 1555.13 cm-1 which indicates the possibility of a cluster C = C, as well as identification by using specific reagents. From the above observations indicate that isolates classes of flavonoids suspected.

PENGARUH PEMBERIAN EKSTRAK ETANOL DAUN BUAS-BUAS (Premna cordifolia. LINN) TERHADAP KADAR MDA TIKUS WISTAR JANTAN PASCA PAPARAN ASAP ROKOK Asri Adyttia; Eka Kartika Untari; Sri Wahdaningsih
Jurnal Fitofarmaka Indonesia Vol 1, No 2 (2014): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Free radical from cigarrete smoke can cause lipid peroxidation that could lead to tissue damage. Tissue damage can be identified by increased levels of MDA (Malondialdehyde). Leavesof buas-buas (Premna cordifolia. Linn) has an antioxidant activity in invitro study. This study aimed to analyze the effect of P. cordifolia leaves extract on the levels of malondialdehyde (MDA) after exposure to cigarette smoke. The simplicia extracted by maseration using 70% ethanol. Twenty four wistar strain of Rattus novergicus were divided into six groups , i.e. : normal group without any treatment, positive control group with cigarette smoke exposure and vitamin e treatment, negative control groupwith only cigarette smoke exposure, treatment groupwith cigarette smoke exposure and ethanolic extract from P. cordifolialeaves with doses 200; 400; 600 mg/kg of body weight/day. All rats were treated for 14 days using 3 cigarette non filetered each day. After 14 days, plasma MDA was measured in this research. Measurement of plasma MDA are using Spectrophotometer UV-Vis in 532.2 nm. MDA level in this study was analyzed by the Kruskal-Wallis and Mann-Whitney test. The result showed that plasma MDA level of groupreceived ethanol extract of P. cordifolia leaves doses at 600 mg/kg of body weight/day significantly (p<0.05)lower than negative control group and not significantly differ (p<0.05) to normal group and positive control group.

AKTIFITAS EKSTRAK JAHE MERAH DALAM MENURUNKAN ASAM URAT PADA KELINCI SERTA ISOLASI DAN IDENTIFIKASI SENYAWA BIOAKTIFNYA Subehan Lallo; Muhammad Mirwan; Adrianti Palino; Nursamsiar Nursamsiar; Besse Hardianti
Jurnal Fitofarmaka Indonesia Vol 5, No 1 (2018): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Jahe merah (Zingiber officinalle var. Amarum) merupakan salah satu tumbuhan yang banyak digunakan sebagai bumbu makanan sehari-hari dan juga berkhasiat sebagai obat tradisional untuk mengobati berbagai penyakit termasuk asam urat. Penelitian ini bertujuan untuk menguji aktifitas biologi dari jahe merah dan mengisolasi dan mengidentifikasi senyawa bioaktif yang tekandung di dalam ekstraknya. Berdasarkan penelitian yang dilakukan terhadap ekstrak etanol jahe merah memperlihatkan kemampuannya dalam menurunkan asam urat pada kelinci yang diinduksi dengan kalium bromat (KBrO3) pada konsentrasi 0,6 b/v yang diamati pada 1 dan 3 jam setelah diinduksi dan dibandingkan dengan allopurinol yang digunakan sebagai positif kontrolnya. Ekstrak etanol jahe merah juga memperlihatkan hubungan konsentrasi dengan penurunan asam urat pada kelinci. Isolasi senyawa bioaktif dalam tanaman ini telah dilakukan dengan menggunakan metode kromatografi dan identifikasi stukturnya didasarkan pada analisis data spektrofotometri dan NMR. Berdasarkan data spectra yang diperoleh terhadap senyawa yang paling dominan yang berhasil diisolasi dan diidentifikasi adalah senyawa 6-gingerol. Hal ini menunjukkan bahwa ekstrak etanol jahe merah memiliki aktifitas dalam menurunkan kadar asam urat dengan senyawa utama 6-gingerol.

ISOLASI DAN KARAKTERISASI BAKTERI ASAM LAKTAT DARI LIMBAH CAIR RENDAMAN KACANG KEDELAI Zakiyah Zahra Nur Amaliah; Saiful Bahri; Puteri Amelia
Jurnal Fitofarmaka Indonesia Vol 5, No 1 (2018): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Tempe is an Indonesia traditional food, which in the manufacturers have a liquid waste that no use again namely soybean soaking water. Lactic Acid Bacteria (LAB) has been known at every stage of tempeh production, included at soaking soybeans. This study aimed to isolate and characterize LAB contained in soybean soaking water liquid waste. After serial dilution to 10-7, soybean soaking water liquid waste was inoculated on the MRSA contained 1% CaCO3. After incubation, there are 8 isolates which produce clear zone around their colonies with different colony morphology suspected as LAB. Morphological, physiological and biochemical characteristics were employed to identify LAB. All isolates were non-spore forming, non-motile, catalase negative, grow well at 37° and 45°C, could be able to grow in the presence of 4% and 6.5% sodium chloride. The results of safety test showed all isolates negative for hemolytic activity. Seven of eight isolates are Gram-positive, while one is a Gram-negative. But only Gram-positive were chosen as they represent the LAB characteristic. Seven isolates were identified as Lactobacillus with heterofermentative as the type fermentation. In this study, Lactobacillus casei ATCC 393 used as reference strain

EFEK SENYAWA BIOAKTIF KAYU MANIS Cinnamomum burmanii NEES EX.BL.) TERHADAP DIABETES MELITUS: KAJIAN PUSTAKA Emilda Emilda
Jurnal Fitofarmaka Indonesia Vol 5, No 1 (2018): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Diabetes Mellitus (DM) is a chronic disorder of carbohydrate metabolism (glucose) in the body and its prevalence is getting higher. Until 2015, 10 million cases of DM found in Indonesia and allegedly ever increasing. Type II DM is the most common types of DM in the world and its characterized by insulin resistance and β cell damage. Due to the serious side effects caused when taking chemical antidabetes drugs, herbal medicine searches from natural materials continue to be done. Various spesieces of cinnamon plants have been studied and known to have antidiabetic activity. One of them is Cinnamomum burmanii which is found in Indonesia. Among the spesieces of cinnamon have the same health benefits including antidiabetes, antimicrobial, anti-fungal, antiviral, antioxidant, antitumor etc. Although the antidiabetic mechanism of cinnamon is still debated, it is thought that cinnamon affects several insulin signaling pathways, among others, in insulin receptors, glucose transporter 4 (GLUT 4), glucose transporter-1 (GLUT 1), peroxisome proliferator activator receptor (PPAR), α activity glucosidase etc. This activity is caused of the bioactive compounds it contains. The main compounds that have hypoglycemic activity are Methylhidroxy Calcone Polymer (MHCP), sinamaldehyde, and polymer pro-ayanine type-A polymers or proanthocyanidin.

PROFIL FITOKIMIA DAN PEMERIKSAAN FARMAKOGNOSTIK DAUN ANTING-ANTING (Acalypha indica. L) Selpida Handayani; Abd. Kadir; Masdiana Masdiana
Jurnal Fitofarmaka Indonesia Vol 5, No 1 (2018): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

The Anting-anting (Acalypha indica L.) plant of the tribal Euphorbiaceae is one type of plant commonly used as a medicinal plant. The Purpose of This study is to get the morphology data, anatomy, organoleptic, physical determination of powders, powder ekstrabilitas determination, identification of chemical reactions and thin layer chromatography of Anting-anting (Acalypha indica L.) plant. Extraction of Anting-anting (Acalypha indica L.) leaf is using 96% ethanol by maceration method. Longitudinal slices showed stomata leaf anatomy anisositik type. Fisic desition include 16,36 % decision of dust level 5,16% decision of unsoluble dust in acid level. Decision of cansentrate level that include 25,16% consentrate level of water soluble and 26,36% consentrate level of etanol soluble. The results of this study concluded thet the leaf powder Anting-anting (Acalypha indica L.) is positive for flavanoid, alkaloid, steroid, saponin and aleuron.

POTENSI ANTIBAKTERI EKSTRAK ETANOL JAMUR KANCING (Agaricus bisporus) SEBAGAI ANTIBAKTERI Siska Nuryanti; Fitriana Fitriana
Jurnal Fitofarmaka Indonesia Vol 5, No 1 (2018): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

A research had been done on antibacterial activity of extract and the aim was to determine the antibacterial activity and inhibitory potency. The research was started by screening test using Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, Staphylococcus epidermidis, Shigella dysenteriae, Staphylococcus aureus, Streptococcus mutans and Vibrio cholerae. Results showed that the Agaricus bisporus ekstract inhibited Bacillus subtilis, Shigella dysenteriae, Staphylococcus aureus, and Vibrio cholera at concentrations 0,1% and 1%. The results obtained Minimum Inhibitory Concentration (MIC) Agaricus bisporus extract against at concentrations of 0,1%. In the Minimum Bactericidal Concentration (MBC) test Agaricus bisporus extract against at concentrations of 0,8%. Agaricus bisporus extract has antibacterial activity wich was indicated by the inhibitory zone diameter. The biggest inhibitory zone diameter of Agaricus bisporus contained in bacteria Bacillus subtilis on the concentration of 6.4% (13 mm)

Page 5 of 15 | Total Record : 150

3 4 5 6 7

Filter by Year

2014 2025

Filter By Issues

All Issue Vol 12, No 1 (2025): JURNAL FITOFARMAKA INDONESIA Vol 11, No 3 (2024): JURNAL FITOFARMAKA INDONESIA (ENGLISH EDITION) Vol 11, No 2 (2024): JURNAL FITOFARMAKA INDONESIA Vol 11, No 1 (2024): JURNAL FITOFARMAKA INDONESIA Vol 10, No 3 (2023): JURNAL FITOFARMAKA INDONESIA (ENGLISH EDITION) Vol 10, No 2 (2023): JURNAL FITOFARMAKA INDONESIA Vol 10, No 1 (2023): JURNAL FITOFARMAKA INDONESIA Vol 9, No 3 (2022): JURNAL FITOFARMAKA INDONESIA (ENGLISH EDITION) Vol 9, No 2 (2022): JURNAL FITOFARMAKA INDONESIA Vol 9, No 1 (2022): JURNAL FITOFARMAKA INDONESIA Vol 8, No 3 (2021): JURNAL FITOFARMAKA INDONESIA Vol 8, No 2 (2021): JURNAL FITOFARMAKA INDONESIA Vol 8, No 1 (2021): JURNAL FITOFARMAKA INDONESIA Vol 7, No 3 (2020): JURNAL FITOFARMAKA INDONESIA (English Edition) Vol 7, No 2 (2020): JURNAL FITOFARMAKA INDONESIA Vol 7, No 1 (2020): JURNAL FITOFARMAKA INDONESIA Vol 6, No 2 (2019): JURNAL FITOFARMAKA INDONESIA Vol 6, No 1 (2019): JURNAL FITOFARMAKA INDONESIA Vol 5, No 2 (2018): JURNAL FITOFARMAKA INDONESIA Vol 5, No 1 (2018): JURNAL FITOFARMAKA INDONESIA Vol 4, No 2 (2017): JURNAL FITOFARMAKA INDONESIA Vol 4, No 1 (2017): JURNAL FITOFARMAKA INDONESIA Vol 3, No 2 (2016): JURNAL FITOFARMAKA INDONESIA Vol 3, No 2 (2016): JURNAL FITOFARMAKA INDONESIA Vol 3, No 1 (2016): JURNAL FITOFARMAKA INDONESIA Vol 2, No 2 (2015): JURNAL FITOFARMAKA INDONESIA Vol 2, No 1 (2015): JURNAL FITOFARMAKA INDONESIA Vol 1, No 2 (2014): JURNAL FITOFARMAKA INDONESIA Vol 1, No 1 (2014): JURNAL FITOFARMAKA INDONESIA More Issue

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
-

Editorial Address
-

Location
Kota makassar,

Sulawesi selatan

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name -

Contact Email -

Phone -

Journal Mail Official -

Editorial Address -

Location Kota makassar, Sulawesi selatan INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
-

Editorial Address
-

Location
Kota makassar,

Sulawesi selatan

INDONESIA