cover
Contact Name
Rachmat Kosman
Contact Email
jurnal.farmasi@umi.ac.id
Phone
+6281342695698
Journal Mail Official
rachmatkosman@umi.ac.id
Editorial Address
Fakultas Farmasi UMI, Kampus II, Universitas Muslim Indonesia, Jl. Urip Sumohardjo Km.5, Makassar
Location
Kota makassar,
Sulawesi selatan
INDONESIA
As-syifaa Jurnal Farmasi
ISSN : 20854714     EISSN : 25029444     DOI : -
Core Subject : Health, Science,
As-Syifaa Jurnal Farmasi receives manuscripts in Indonesian Language (Bahasa Indonesia) with abstracts in bilingual, both Indonesian and English. We’re open for various fields such as: Pharmacology and Toxicology, Pharmaceutical Microbiology and Biotechnology, Herbal Medicines, Pharmaceutics, Pharmaceutical Chemistry, Drug Discovery, Pharmacokinetics, Pharmaceutical Biology, Community and Clinical Pharmacy, Pharmaceutical Care.
Articles 397 Documents
KARAKTERISASI ISOLAT BAKTERI PENGHASIL SELULOSA DARI BUAH NAGA MERAH (Hylocereus polyrhizus) Siska Nuryanti; Fitriana Fitriana; A. Rini Pratiwi
As-Syifaa Jurnal Farmasi Vol 13, No 1 (2021): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v13i1.770

Abstract

Cellulose is a natural polymer widely used for general industrial purposes. The development of science utilizes bacteria from certain fruits to produce biosellulose. Red dragon fruit (Hylocereus polyrhizus) contains a lot of sugar which can be bioconverted to cellulose by cellulose- producing lines. The research aimed to obtain bacteria from red dragon fruit with the potential to produce cellulose, then conduct morphological and biochemical characterization. The research was conducted by the isolation of bacteria from the fruit, purification, and screening tests using Hestrin-Schramm medium. The isolates obtained were characterized morphologically through macroscopic and microscopic observation and the biochemically through catalase test, carbohydrate fermentation, starch and gelatin hydrolysis, motility, and IMViC (Indole, Methyl red, Voges- Proskauer, Citrate). The results showed that 4 bacterial isolates had the potential to produce cellulose. Based on Bergey's Manual of Systematic Bacteriology, 3 bacterial genera were obtained, namely Acetobacter, Gluconacetobacter, and Azotobacter. The results of the characteristics of the isolates obtained at IBBN 2-2 were positive in the catalase test, sucrose and lactose fermentation, and methyl red. IBBN 3-1 was positive in the catalase test, sugar fermentation, starch hydrolysis, methyl red, and citrate. IBBN 3-2 was positive in the sucrose and glucose fermentation test, gelatin hydrolysis and 4-1 IBBN was positive in the sucrose fermentation test and gelatin hydrolysis.
DAFTAR ISI AS-SYIFAA JURNAL FARMASI 14.1 (2022) CONTENT CONTENT
As-Syifaa Jurnal Farmasi Vol 14, No 1 (2022): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

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Abstract

UJI EFEK EPITELISASI EKSTRAK BATANG WOLE WOE ASAL KABUPATEN HALMAHERA TENGAH TERHADAP PENYEMBUHAN LUKA BAKAR PADA TIKUS Safriani Rahman; Rachmat Kosman; Sitti Amirah
As-Syifaa Jurnal Farmasi Vol 14, No 1 (2022): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v14i1.792

Abstract

Wole woe is a native plant of Indonesia which is widely used by the people of Central Halmahera as a medicinal plant. Empirically this plant is widely used for wound treatment. This study aims to determine the effect of epithelialization of wole woe stem extract and determine the effective concentration and duration of wound healing in rats after administration of wole woe stem extract. This research was conducted experimentally in a laboratory using 25 rats which were divided into 5 groups consisting of 1 control group, 1 comparison group, and 3 treatment groups of wole woe stem extract. Wound induction was carried out using a 100 0C hot plate measuring 2x2 cm and affixed to the surface of the rat's back skin for 2 seconds. After a burn is formed, the extract is applied 2 times a day for 21 days. Observations on wound healing were carried out macroscopically and measuring the surface area of the wound. The results showed that the administration of wole woe bark extract influenced healing second-degree burns in rats. The results of statistical analysis showed that there was no difference between the comparison group and the extract test group (p>0.05). Based on the percent reduction in wound, the most effective concentration in wound healing was 5% (99.75%). Wound healing time in rats was 21 days.
PENENTUAN AKTIVITAS ANTIBAKTERI EKSTRAK ISOLAT FUNGI ENDOFIT DARI DAUN GALING-GALING (Cayratia trifolia L) Ayyub Harly Nurung; Fitriana Fitriana; Herwin Herwin
As-Syifaa Jurnal Farmasi Vol 14, No 1 (2022): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v14i1.785

Abstract

Utilization of wild plants around us needs to be done to expand the chances of wild plants being used as traditional medicine. These plants have the main content of the active compounds in the form of steroids, terpenoids, flavonoids, tannins and is reported to have antibacterial activity. This research aims to determine the concentration of endophytic fungi isolates IDGG 02, IDGG 03 and IDGG 06 from the leaves of galing-galing (Cayratia trifolia L). The first stage purification isolates of endophytic fungi in order to obtain single isolates. Then fermented using a shaker for 21 days at room temperature. Fermented extracted with ethyl acetate solvent using a liquid-liquid extraction methods to obtain a dry extract. Testing the minimum inhibitory concentration (MIC) with concentrations of 2048, 1024, 512, 256, 128, 64, 32, 16, 8 and 4 µg / mL and testing for antibacterial activity using agar diffusion methods against bacteria Staphylococcus aureus, Staphlococcus epidermidis, Escherichia coli and Vibrio cholerae.The results obtained MIC 2048 MIC ug / mL to extract isolates IDGG 02 and IDGG 06, while the extract obtained 03 isolates IDGG 1024 MIC ug / ml against all bacteria. Results of testing the antibacterial activity of endophytic fungi isolated extract IDGG 02, 03 IDGG produce diameter zone of inhibition at a concentration of 2048 mg / mL against Staphylococcus aureus, Staphlococcus epidermidis, Escherichia coli and Vibrio cholerae.
AKTIVITAS ANTIMIKROBA EKSTRAK ETANOL BATANG WOLE WOE ASAL HALMAHERA TENGAH TERHADAP BAKTERI GRAM POSITIF Staphylococcus epidermidis DAN Staphylococcus aureus Fitriana Fitriana; Sitti Amirah; Safriani Rahman
As-Syifaa Jurnal Farmasi Vol 14, No 1 (2022): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v14i1.793

Abstract

The wole woe plant is one of the plants empirically used by the Weda community in Central Halmahera district as a traditional medicine to treat various diseases such as breast cancer, cysts, vaginal discharge, diabetes mellitus, wounds, dysentery, cholesterol, and gout. Therefore, a study was conducted on the antimicrobial activity of the ethanolic extract of wole woe stems against gram-positive bacteria S. epidermidis and S. aureus with the aim of determining the concentration that provides antimicrobial activity of the ethanolic extract of wole woe stems by using the agar diffusion method. The results obtained in the screening test gave activity at a concentration of 0.1% and the results of the minimum inhibitory concentration test (MIC) and the minimum killing concentration test (MBC) obtained a MIC value of 1.6% for S. epidermidis bacteria and 0.8% for S. aureus bacteria, while the MBC value is 1.6% for both bacteria. The results of statistical tests on the diameter of the inhibition zone from the antimicrobial activity test against S. epidermidis and S. aureus, showed that there was a difference in the ability to inhibit bacterial growth between the positive control and the test concentration group of 2.5%, 5% and 10%. In the ratio of the inhibitory ability of bacteria at a spesific concentration, the test results showed that S. epidermidis bacteria had different bacterial growth inhibition abilities with S. aureus bacteria. Based on the results obtained, the ethanol extract of wole woe stems has potential as an antimicrobial.
PROFIL PENYIMPANAN OBAT DI UNIT PELAKSANAAN TEKNIS DAERAH (UPTD) PENGELOLAAN OBAT DINAS KESEHATAN KOTA MAKASSAR Andi Muflihunna; Iskandar Zulkarnain; Hasni. A Hasni. A
As-Syifaa Jurnal Farmasi Vol 14, No 1 (2022): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v14i1.786

Abstract

The pharmacy storage facility is responsible for maintaining the supply of medicines to avoid damage and expiration as well as maintaining the quality of medicines stored in the facility. As a result, this investigation concerning the profile of drug storage at the UPTD of Drug Management of Makassar City Health Office, is necessary. The study aimed to determine the drug storage profile in the UPTD of Makassar City Health Office. The present study employs a descriptive qualitative approach. Direct observation, in- depth interviews, and document analysis were used to collect data. The informants for this study were the head of the UPTD and pharmaceutical personnel at the UPTD of Drug Management of Makassar City Health Office. The aspects examined and percentages obtained were facilities and spatial arrangements (82.3 percent), drug stock preparation (81.8 percent), stock card recording (87.5 percent), and checking conditions and drug storage (87.5 percent). The results showed that all areas examined fell into the very good category and were consistent with the guidelines of Health Ministry of the Republic of Indonesia 2002, Regulation numbers 72, 73, 74 of 2016, and Technical Guidelines of 2019. Even though drug storage activities are not directly related to patients, ignoring them will result in significant losses for the Health Office
ANALISIS AKTIVITAS PERLINDUNGAN SINAR UV EKSTRAK ETANOL DAUN PANDAN WANGI (Pandanus amaryllifolius Roxb.) BERDASARKAN NILAI SUN PROTECTION FACTOR St. Maryam; Elka Praningsih; Andi Trihadi Kusuma
As-Syifaa Jurnal Farmasi Vol 14, No 1 (2022): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v14i1.791

Abstract

UV rays have a negative impact on the skin, but can be minimized by using UV-protective ingredients. The leaves of Pandan Wangi (Pandanus amaryllifolius Roxb.). Contain alkaloid compounds, flavonoids, saponins, tanins, polyphenols  which function as natural antioxidants. The purpose of study is determine the UV protection activity of the ethanol extract of fragrant pandan leaves. Based on the Sun Protection Factor (SPF) value using the UV- Vis Spectrophotometric method at wavelengths 290, 295, 300, 310, 315, 320 nm. The result showed that fragrant pandanus leaves (Pandanus amaryllifolius Roxb.) Had a minimum UV protection activity value of 3,8979 at a concentration of 1%, extra protection 6,2456 at a concentration of 3%, maximum protection of 9,4603 at a concentration of 5%.
STUDI ETNOFARMASI TANAMAN OBAT TRADISIONAL PADA MASYARAKAT DI KECAMATAN PENRANG, KABUPATEN WAJO, PROVINSI SULAWESI SELATAN Virsa Handayani; Andi Amaliah Dahlia; Andi Fenny Nurvadillah
As-Syifaa Jurnal Farmasi Vol 14, No 1 (2022): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v14i1.841

Abstract

Indonesian community have been utillsing medicinal plants for years as an alternative treatment of a disease. Penrang is one of the areas located in Wajo Regency, South Sulawesi Province whre the majority is Buginese tribe. They use plants as a traditional medicine to cure various diseases. This research aimed to find out the types of plants used by local people in treating plants through shamans, community leaders and people who have knowledge about medicinal plants. The research method was purposive sampling. The research included 33 families and 54 species of ethnopharmacy still remains in the community to treat disesases that are used single-use or concoction, called jappi-jappi
STUDI PENGETAHUAN DAN SIKAP TERHADAP PENGGUNAAN TUMBUHAN OBAT UNTUK MENGOBATI REMATIK PADA MASYARAKAT KOTA BAUBAU SULAWESI TENGGARA Nur Wahyuni Arifin; Rahmawati Rahmawati; Sukmawati Sukmawati
As-Syifaa Jurnal Farmasi Vol 14, No 1 (2022): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v14i1.790

Abstract

The use of plants as medicine or traditional ingredients has been carried out since ancient times by people in Indonesia, either as an effort to cure or prevent a disease. One of the diseases that is often found in the community is rheumatism. Rheumatism is a chronic systemic inflammatory disease that attacks the joints, especially the synovial joints. This study aims to identify and obtain an overview of knowledge and attitudes towards the use of medicinal plants to treat rheumatism in people in the city of Baubau, Southeast Sulawesi. This research uses descriptive non- experimental method. In this study, a questionnaire was used as an instrument to collect data. The number of samples in this study were 90 respondents with a sampling technique, namely proposive sampling. Based on the research that has been done, it is found that 65.6% have good knowledge and 57.8% of the respondents show a positive attitude. Thus it can be concluded that the people in Baubau City, Southeast Sulawesi have good knowledge and show a positive attitude towards the use of medicinal plants to treat rheumatism.
SAMPUL AS-SYIFAA JURNAL FARMASI 14.1 (2022) COVER COVER
As-Syifaa Jurnal Farmasi Vol 14, No 1 (2022): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

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