cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Rachmat Kosman
Contact Email
jurnal.farmasi@umi.ac.id
Phone
+6281342695698
Journal Mail Official
rachmatkosman@umi.ac.id
Editorial Address
Fakultas Farmasi UMI, Kampus II, Universitas Muslim Indonesia, Jl. Urip Sumohardjo Km.5, Makassar
Location
Kota makassar,
Sulawesi selatan
INDONESIA
As-syifaa Jurnal Farmasi
Published by Universitas Muslim Indonesia
ISSN : 20854714     EISSN : 25029444     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology
As-Syifaa Jurnal Farmasi receives manuscripts in Indonesian Language (Bahasa Indonesia) with abstracts in bilingual, both Indonesian and English. We’re open for various fields such as: Pharmacology and Toxicology, Pharmaceutical Microbiology and Biotechnology, Herbal Medicines, Pharmaceutics, Pharmaceutical Chemistry, Drug Discovery, Pharmacokinetics, Pharmaceutical Biology, Community and Clinical Pharmacy, Pharmaceutical Care.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 397 Documents
 29   30   31   32   33 
AKTIVITAS ANTIOKSIDAN EKSTRAK FERMENTAT ISOLAT FUNGI ENDOFIT BIJI BUAH KENARI (Canarium indicum L.) SECARA KLT-AUTOGRAFI Nurul Khatimah Naim; Herwin Herwin; Fitriana Fitriana; Ayyub Harly Nurung
As-Syifaa Jurnal Farmasi Vol 13, No 2 (2021): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v13i2.780

Abstract

Walnut seeds (Canarium indicum L.) contain tannin, flavonoids, carotenoids which is potentially fungtioning as antioxidants. The research aimed to examine the antioxidant activity of fermentate extract of walnut seeds endophytic fungi by autography-TLC. The result of the endophytic fungi isolation in Walnut seeds (Canarium indicum L.) obtained 5 isolates with characteristics. The test result of screening free antiradical activity obtained that isolate 4th was active as an antioxidant indicated by the presence of brown spots with the addition of 1,1-diphenyl-2-picrylhydrazyl 0.004%. Isolate 4th was fermented using Maltosa Yeast Broth (MYB) medium to obtain fermentate supernatant and mycelia. The Fermentate of supernantant of isolate 4th was extracted to obtained supernantant of ethyl acetate extract. Based on the result of free antiradical activity test of ethyl acetate fermentate extract isolate 4th by autography-TLC using ethyl acetate: methanol: water eluent (6:2:1), obtained Rf 0.78 value active as free antiradical by spraying 1,1diphenyl-2-picrylhydrazil 0.004%.
FORMULASI DAN UJI AKTIVITAS ANTIOKSIDAN BODY LOTION EKSTRAK ETANOL DAUN KEMANGI (Ocimum cannum Sims.) DENGAN METODE DPPH (1,1 – diphenyl-2- picrylhydrazyl) Yani Ambari; Arlin Oscardini Saputri; Iif Hanifa Nurrosyidah
As-Syifaa Jurnal Farmasi Vol 13, No 2 (2021): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v13i2.775

Abstract

Basil leaves (Ocimum cannum Sims.) Are known to contain alkaloids, flavonoids, saponins, tannins, polyphenols, and triterpenoids. One of the compounds contained in the basil leaves (Ocimum cannum Sims.) Is a flavonoid which has antioxidant activity. Compounds that have antioxidant activity are known to prevent premature aging. This study aims to determine that the ethanol extract of basil leaves (Ocimum cannum Sims.) Can be formulated into Body Lotion with good physical stability or stable and to determine the antioxidant activity of Body Lotion ethanol extract of basil leaves (Ocimum cannum Sims.). The ethanol extract of basil leaves (Ocimum cannum Sims.) Was obtained by remaseration method using ethanol 96% with a yield percentage of 7.09%. Body lotion ethanol extract of basil leaves (Ocimum cannum Sims.) Is made in 3 formulas, which contain extracts F1 (0.5%), F2 (1%), and F3 (1.5%). Body lotion preparations were also tested for physical stability using the cycling test which included organoleptic, homogeneity, pH, dispersal, and adhesion tests. Then proceed to the determination of antioxidant activity carried out by the DPPH free radical reduction method by calculating the IC50 value. The results showed that the ethanol extract of basil leaves (Ocimum cannum Sims.) Has antioxidant activity with IC50 value of 7.05 ppm with AAI value of 14.1 and body lotion preparations can be made. The results of the body lotion antioxidant activity test of basil leaves ethanol extract (Ocimum cannum Sims.) Showed that, F3 had the strongest antioxidant activity namely IC50 18.36 ppm with AAI value of 11.9 then followed by F2 namely IC50 25.2 ppm with AAI value 3.9, and F1, namely IC50 90.5 ppm with AAI value of 14.1. Based on the research results obtained, it can be concluded that the higher the concentration of ethanol extract of basil leaves (Ocimum cannum Sims.) Added, the antioxidant activity of the body lotion will be stronger
PENGUJIAN AKTIVITAS EKSTRAK ETANOL KULIT BUAH KECOMBRANG (Etlingera elatior (Jack) R.M.Sm) SEBAGAI INHIBITOR TIROSINASE Harti Widiastuti; Zainal Abidin
As-Syifaa Jurnal Farmasi Vol 13, No 1 (2021): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v13i1.769

Abstract

Healthy skin should have a flat surface, the texture is soft, elastic, and have the same skin color. Skin color is determined by the size, number and distribution of melanin pigment. Pigment brownish pigment melanin is to protect the skin from UV light scattering. An enzyme that plays a role in this browning reaction is tyrosinase. Based on this research is conducted on the fruit skin kecombrang to see the activity of the enzyme tyrosinase barriers and whether rind kecombrang can inhibit tyrosinase enzyme and with the aim to utilize natural materials and waste that can inhibit the enzyme tyrosinase and can be used as a skin whitheter. Research iniated by the extraction of fruit skins kecombrang using etanol. Flavonid content test on the sample using Mg powder and HCl p, the results show a color change from dark brown to yellow. So positive it contains flavonoids. Measurements were contucted on a maximum wavelength of 478,003 nm, using the substrate L-tyrosine and the enzyme tyrosinase. Using comparators hidroquinon. Of the results of this study concluded that kecombrang fruit peel ectract at a concentration of 2 mg/mL could inhibit amounted to 55,92% and a concentration of 2,5 mg/mL could inhibit amounted to 56,58%
FORMULASI SEDIAAN GEL EKSTRAK DAUN SUKUN (Artocarpus altilis) SEBAGAI PENYEMBUHAN LUKA BAKAR PADA KELINCI DENGAN VARIASI KONSENTRASI CARBOPOL 940 SEBAGAI GELLING AGENT Putri Rinda Sari; Supriyadi Supriyadi; Inaratul Rizkhy Hanifah
As-Syifaa Jurnal Farmasi Vol 13, No 2 (2021): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v13i2.781

Abstract

Breadfruit leaves are medicinal plants containing compounds such as flavonoids, saponins, tannins, polyphenols that function in wound healing. This study aimed to determine the variation of the concentration of the gelling agent carbopol 940 on the physical properties of the gel and the duration of the burn wound healing process on gel administration. This study used New Zealand White rabbits. They were divided into five groups. They were positive control (bioskin®), negative control, breadfruit leaf extract gel formula with variations in carbopol concentrations of 0,5%, 1%, and 2%, respectively. Burn percentage was analyzed using SPSS with Kolmogorov- Smirnov test to see normality, Levene test to see homogeneity, if the data is normally distributed and homogeneous, followed by Two Way ANOVA analysis with Post hoc Tukey significance of 0.005. The results of breadfruit leaf extract variations in the gelling agent carbopol 940 affect the physical properties. The increase in the concentration of the gelling agent causes an increase in viscosity, adhesion and decreases dispersion. Variations in the concentration of carbopol effective for healing burns was formula II (breadfruit leaf extract gel formula with variations in carbopol concentrations of 1%). Therefore, the provision of breadfruit leaf extract gel can accelerate the healing process of burns
AKTIVITAS ANTIOKSIDAN EKSTRAK DAUN KELOR (Moringa oleifera L.) DAN PENGEMBANGANNYA MENJADI BENTUK SEDIAAN GEL Nur Asisi; Uliyah Uliyah; Nurul Fitrah Amaliyah; A. Hasrawati
As-Syifaa Jurnal Farmasi Vol 13, No 1 (2021): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v13i1.757

Abstract

Antioxidants are used to prevent the oxidation of free radical compounds which have a bad impact on the body, including the skin.  One source of antioxidants derived from natural ingredients is Moringa leaves.  Moringa leaves have a number of benefits due to the many active chemical compounds.  The antioxidant activity of Moringa leaves can be optimized by developing Moringa leaves into a gel dosage form.  A literature review regarding the compound content and activity of Moringa leaves was carried out to obtain scientific data that can be used in the development of Moringa leaves as an antioxidant.  Narrative review with data sources from Science Direct, Pubmed, CiterSeerX, and Google Scholars. The Inclusion and exclusion criteria were set to obtain literature according to the scope of the study.  The results of the literature review showed that Moringa leaves contain the main active compounds of polyphenols and flavonoids which have strong antioxidant activity.  Gel dosage form is one of the best choices to optimize the antioxidant activity of Moringa leaves.  HPMC, carbopol and xanthan gum are gelling agent was produced a gel preparation with good pharmaceutical characteristics.
PERBANDINGAN MEDICATION ERROR PADA PERESEPAN ELEKTRONIK DAN PERESEPAN MANUAL PADA TAHAP PRESCRIBING DI APOTEK KOTA PALU Alwiyah Mukaddas; Ingrid Faustine; Nofriyanti Nofriyanti
As-Syifaa Jurnal Farmasi Vol 13, No 2 (2021): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v13i2.776

Abstract

Prescribing drugs is now growing, as evidenced by the existence of electronic prescribing that have been applied in several hospitals and pharmacies. The development of this prescribing method does not rule out the possibility of increasing the incidence of medication errors in prescribing. So, it is necessary to identify the prescribing that has been implemented, especially in drugstore at Palu City. The purpose of this study was to look at the comparison of medication errors at the prescribing stage which included aspects of prescribing completeness and therapeutic errors in electronic prescribing at Drugstore X and manual prescribing at Drugstore Y in Palu city in 2018. This type of research is a descriptive study with retrospective data collection. Samples taken in the form of secondary data are prescribing using purposive sampling method. The results obtained in this study are, the prevalence of medication error at the prescribing stage of electronic prescribing in drugstore at Palu City includes data, patient's body weight is 2%, doctor's license 100%, doctor's telephone number 100%, doctor's initial 100%, dosage form 97% and 90% strength of the drug. While the prevalence of medication error at the prescribing stage of manual prescribing in Drugstore Palu City is data, the patient's age is 2%, the patient's body weight is 99.1%, the patient's sex is 100%, the doctor's license is 91.6%, the doctor's telephone number is 80%, initial doctor 42.7%, 88% dosage form and 65% drug strength. Based on these results, it can be concluded that the use of electronic prescribing is better than manual prescribing.
DAFTAR ISI AS-SYIFAA JURNAL FARMASI 13.1 DAFTAR ISI
As-Syifaa Jurnal Farmasi Vol 13, No 1 (2021): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

PENETAPAN KADAR FLAVONOID FRAKSI ETIL ASETAT DAUN KARET KEBO (Ficus elastica) DENGAN METODE SPEKTROFOTOMETRI UV-VIS Asriani Suhaenah; Mamat Pratama; A.Hesti Wulandasari Amir
As-Syifaa Jurnal Farmasi Vol 13, No 1 (2021): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v13i1.767

Abstract

Rubber plant (Ficus elastica) is a plant that has been widely used as traditional medicine. The leaves of this plant are used as medicine for coughing up blood, laxative urine, relieving pain and improving blood circulation. Various kinds of properties and benefits of the rubber plant (Ficus elastica) cannot be separated from  the compounds contained in it such as saponins, polyphenols, and flavonoids.  The purposes of this research is to determine the flavonoid total content in the ethyl acetate fraction of the rubber leaves (Ficus elastica). Simplicia was extracted by maceration method, using 96% ethanol solvent for 3x24 hours and partitioned with a mixture of 96% ethanol - aquadest (2:3) and ethyl acetate as a solvent. Determination of flavonoid content using UV-Vis spectrophotometry method , with a maximum wavelength of 438 nm, using quercetin as a comparison. The results of this research obtained that the total flavonoid content in the ethyl acetate fraction of  rubber leaves (Ficus elastica) was an average of 74,345 mgQE/g fraction.
EFEK ANTINEFROTOKSISITAS EKSTRAK ETANOL DAUN PANDAN WANGI (Pandanus amaryllifolius Roxb.) DENGAN PARAMETER KADAR UREUM TIKUS PUTIH Sukmawati Sukmawati; Rahmawati Rahmawati; Kenanga Isyanda A
As-Syifaa Jurnal Farmasi Vol 13, No 2 (2021): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v13i2.779

Abstract

Nephrotoxicity caused by chemical compounds such as drugs. This condition can cause an increase in urea levels. Antioxidants used to inhibit nephrotoxicity by protect and repair cells. One of the plants as antioxidant is the pandan wangi leaf (Pandanus amaryllifolius Roxb.) which contains phenolic to absorb and neutralize free radicals or decompose peroxides. This study aimed to examine the antinephrotoxicity effect of the ethanolic extract of pandan wangi leaf (Pandanus amaryllifolius Roxb.) on kidney damage with parameters of urea level in rats. Eighteen male Wistar rats were divided into 6 groups. Group 1 as a naive group, group 2 as a negative control by Gentamicin, group 3 as a positive control by amino acid supplement, and groups 4, 5, and 6 were given ethanol extract of pandan wangi leaves at a dose by 125 mg/kgBW, 250 mg/kgBW and 500 mg/kgBW respectively. Nephrotoxicity condition was induced by Gentamicin 100 mg/kgBW (ip) for seven days. The blood samples were taken and measured the serum creatinine levels on days 0, 8th and 21st by Human Analyzer. The results study showed that ethanol extract of pandan wangi leaves at 125 mg/kgBW have the effect as antinephrotoxicity based on decreased ureum levels
GAMBARAN KARAKTERISASI DARI EKSTRAK ETANOL LIMBAH RAMBUT JAGUNG MANIS (Zea mays L.) Yuyun Nikmatus Sholicha; Fita Sari; Dyah Aryantini
As-Syifaa Jurnal Farmasi Vol 13, No 2 (2021): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v13i2.774

Abstract

Traditional plants in Indonesia, have a variety of benefits to overcome various diseases. For example, sweet corn hair waste (Zea mays L), was the residue from corn which is usually used for culinary purposes. Corn silk in previous studies was thought to have pharmacological activity as anti-inflammatory, antidiabetic, and antihypertensive. This study aims to determine the characterization of the ethanol extract of sweet corn hair waste in a hilly area of Kediri, East Java. Characterization to determine the content of active compounds in the ethanol extract of sweet corn hair waste and to ensure the quality of corn hair waste extract when it will be used as raw material for traditional medicine. Characterization includes specific parameters such as screening for metabolites in plant extracts using Thin Layer Chromatography (TLC) and non-specific parameters including determination of water content and specific gravity. The sample used was ethanol extract of sweet corn hair waste (EELRJM) obtained from the hilly area of Kediri, East Java. The results of the specific parameters of the secondary metabolite compound test by TLC indicated that EELRJM contains quercetin compounds of the flavonoid group. Non-specific parameters resulted that the water content of EELRJM did not meet the requirements of the extract monograph because it was suspected that there was an influence on the weather including rainfall.

Page 31 of 40 | Total Record : 397

 29   30   31   32   33 

Filter by Year

2009 2025


Reset
Filter By Issues
All Issue Vol 17, No 1 (2025): AS-SYIFAA JURNAL FARMASI Vol 16, No 2 (2024): AS-SYIFAA JURNAL FARMASI Vol 16, No 1 (2024): AS-SYIFAA JURNAL FARMASI Vol 15, No 2 (2023): AS-SYIFAA JURNAL FARMASI Vol 15, No 1 (2023): AS-SYIFAA JURNAL FARMASI Vol 14, No 2 (2022): AS-SYIFAA JURNAL FARMASI Vol 14, No 1 (2022): AS-SYIFAA JURNAL FARMASI Vol 13, No 2 (2021): AS-SYIFAA JURNAL FARMASI Vol 13, No 1 (2021): AS-SYIFAA JURNAL FARMASI Vol 12, No 2 (2020): AS-SYIFAA JURNAL FARMASI Vol 12, No 1 (2020): AS-SYIFAA JURNAL FARMASI Vol 11, No 2 (2019): AS-SYIFAA Jurnal Farmasi Vol 11, No 1 (2019): AS-SYIFAA Jurnal Farmasi Vol 10, No 2 (2018): AS-SYIFAA Jurnal Farmasi Vol 10, No 1 (2018): AS-SYIFAA Jurnal Farmasi Vol 9, No 2 (2017): AS-SYIFAA Jurnal Farmasi Vol 9, No 1 (2017): AS-SYIFAA Jurnal Farmasi Vol 8, No 2 (2016): AS-SYIFAA Jurnal Farmasi Vol 8, No 1 (2016): AS-SYIFAA Jurnal Farmasi Vol 7, No 2 (2015): AS-SYIFAA Jurnal Farmasi Vol 7, No 1 (2015): AS-SYIFAA Jurnal Farmasi Vol 6, No 2 (2014): AS-SYIFAA Jurnal Farmasi Vol 6, No 1 (2014): AS-SYIFAA Jurnal Farmasi Vol 5, No 2 (2013): AS-SYIFAA Jurnal Farmasi Vol 5, No 1 (2013): AS-SYIFAA Jurnal Farmasi Vol 4, No 2 (2012): AS-SYIFAA Jurnal Farmasi Vol 4, No 1 (2012): AS-SYIFAA Jurnal Farmasi Vol 3, No 2 (2011): AS-SYIFAA Jurnal Farmasi Vol 3, No 1 (2011): AS-SYIFAA Jurnal Farmasi Vol 2, No 2 (2010): AS-SYIFAA Jurnal Farmasi Vol 2, No 1 (2010): AS-SYIFAA Jurnal Farmasi Vol 1, No 2 (2009): AS-SYIFAA Jurnal Farmasi Vol 1, No 1 (2009): AS-SYIFAA Jurnal Farmasi More Issue