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Rachmat Kosman
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As-syifaa Jurnal Farmasi
Published by Universitas Muslim Indonesia
ISSN : 20854714     EISSN : 25029444     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology
As-Syifaa Jurnal Farmasi receives manuscripts in Indonesian Language (Bahasa Indonesia) with abstracts in bilingual, both Indonesian and English. We’re open for various fields such as: Pharmacology and Toxicology, Pharmaceutical Microbiology and Biotechnology, Herbal Medicines, Pharmaceutics, Pharmaceutical Chemistry, Drug Discovery, Pharmacokinetics, Pharmaceutical Biology, Community and Clinical Pharmacy, Pharmaceutical Care.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 397 Documents
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EVALUASI PENYIMPANAN VAKSIN BERDASARKAN PRINSIP SYARIAT ISLAM DI PUSKESMAS MANYARAN KOTA SEMARANG Wijayanti, Rina; Yulianti, Beti; Saraswati, Herluin Nadia
As-Syifaa Jurnal Farmasi Vol 16, No 1 (2024): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v16i1.1075

Abstract

Vaccine management at the health Center still needs special attention where it is known that there are still many cold chain managements, especially vaccines, which have not been managed properly so that there is a lot of damage to the vaccine. The purpose of this study is to determine the description of the suitability and evaluation of vaccine storage based on the principles of Islamic law at Manyaran Health Center, Semarang City. The variable used in this study is a single variable with observations related to vaccine storage, facilities and infrastructure, refrigerator conditions (cold chain management) at Manyaran Healt Center using a checklist sheet for observation. The results showed that each evaluation of vaccine storage, facilities and infrastructure, and the state of the refrigerator at Manyaran Health Center in Semarang City was categorized as good with a percentage of 100%.
SAMPUL AS-SYIFAA JURNAL FARMASI 15.2 (2023) 15.2 (2023), SAMPUL
As-Syifaa Jurnal Farmasi Vol 15, No 2 (2023): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v15i2.1077

Abstract

UJI EFEK ANTIINFLAMASI DARI EKSTRAK ETANOL DAUN AWAR AWAR (Ficus septica Burm L. ) TERHADAP TIKUS PUTIH (Rattus norvegicus) YANG DIINDUKSI KARAGEN Rahmadani, Andi Syafirah; Asmaliani, Ira; Santi, Irma; Sukmawati, Sukmawati; Kosman, Rachmat; Herman, Hendra
As-Syifaa Jurnal Farmasi Vol 16, No 1 (2024): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v16i1.1148

Abstract

Inflammation occurs as a normal protective response to tissue damage caused by physical trauma, harmful chemicals, or microbiological substances. Awar-awar leaves contain flavonoid compounds with anti-inflammatory properties, as they can inhibit cyclooxygenase or lipoxygenase enzymes and prevent the accumulation of leukocytes, thereby reducing the inflammatory response. This study aims to determine the effect and effective dose of ethanol extract from awar-awar leaves (Ficus septica Burm L.) as an anti-inflammatory agent in white rats (Rattus norvegicus). The research involved 25 male white rats divided into five treatment groups: Group I received Na-CMC, Group II received 50 mg Diclofenac Sodium, and Groups III, IV, and V received ethanol extract of awar-awar leaves (Ficus septica Burm L.) at doses of 100, 200, and 400 mg/kgBW, respectively. The results showed that the ethanol extract of awar-awar leaves at a dose of 200 mg/kgBW had the most effective anti-inflammatory effect in reducing the volume and diameter of edema in male rats
PENGARUH SUHU PENYIMPANAN TERHADAP SIFAT FISIK TABLET EFFERVESCENT EKSTRAK KULIT BUAH NAGA MERAH (Hylocereus polyrhizus) DAN BUAH LEMON (Citrus limon L.) Zafira, Areta Thea; Muldiyana, Tya; Santoso, Joko
As-Syifaa Jurnal Farmasi Vol 15, No 2 (2023): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v15i2.1067

Abstract

Effervescent tablet is a dosage form that can produce bubbles originating from an acid and base reaction that forms a gas. The reaction between acids and bases in effervescent tablets is very sensitive to temperature if stored continuously. So that testing for drug stability is very important in evaluating drugs, one of which is by knowing the effect of temperature on drug stability, especially in the form of effervescent tablets. This study aims to determine the effect of storage temperature on the physical properties of effervescent tablets made from red dragon fruit peel extract (Hylocereus polyrhizus) combined with lemon fruit powder (Citrus limon L.). The research method was carried out by storing effervescent tablets at cold temperature (±120C), room temperature (±250C), and warm temperature (±400C). And observed for 1 month with testing every 1 week. The results of this study are storage temperature can affect the physical properties of effervescent tablets made from red dragon fruit peel extract (Hylocereus polyrhizus) with a combination of lemon fruit powder (Citrus limon L.). The best temperature is cold temperature around 120C because at that temperature the acid and base reactions in effervescent tablets are not excessive which results in effervescent tablets still in a stable condition
PENGUJIAN AKTIVITAS ANALGETIK INFUSA HERBA KROKOT (Portulaca oleracea L.) PADA MENCIT PUTIH (Mus musculus) MENGGUNAKAN METODE HOT PLATE Azizah, Rizqi Nur; Putra, Bayu; Alda, Alda
As-Syifaa Jurnal Farmasi Vol 16, No 2 (2024): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v16i2.1274

Abstract

Analgesics are substances that can reduce pain. However, long-term use may trigger side effects. This study aimed to evaluate the analgesic effect of purslane herb infusion (Portulaca oleracea L.) using a pain stimulation method and determine its effective concentration as an analgesic in white mice (Mus musculus). The research was conducted experimentally using male white mice divided into five treatment groups: Group I received Na-CMC as a negative control, Group II received paracetamol suspension as a positive control, and Groups III, IV, and V received the infusion at concentrations of 10%, 20%, and 30%, respectively. Test animals were placed on a hot plate at a temperature of 55°C, and the pain response time to heat stimulation was observed every 30 minutes for 3 hours. The data were statistically analyzed using one-way ANOVA followed by Bonferroni post hoc tests. The positive control group showed no significant differences compared to the groups receiving 10%, 20%, and 30% infusion concentrations. The study concluded that the purslane herb infusion has an analgesic effect in white mice, with an effective concentration of 30%.
POTENSI ANTIDIABETES EKSTRAK ETANOL DAUN KOPASANDA (Chromolaena odorata L.) DENGAN METODE SPEKTROFOTOMETRI UV-Vis Rahmawati, Rahmawati; Widiastuti, Harti; Puspita, Della
As-Syifaa Jurnal Farmasi Vol 16, No 2 (2024): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v16i2.1095

Abstract

Diabetes Mellitus (DM) is a chronic metabolic disease characterized by an increase in glucose levels in the blood. There are many treatment efforts to control and reduce blood glucose levels with natural ingredients. One of the treatment efforts that is expected to treat diabetes comes from plants, namely kopasanda leaves which have many benefits and contain several main compounds such as tannins, phenols, flavonoids, saponins and steroids. Secondary metabolite compounds such as phenols, flavonoid alkaloids and steroids have the potential to act as antidiabetics. The aim of this research was to determine the antidiabetic potential of ethanol extract of kopasanda leaves (Chromolaena odorata L.) in vitro using the Nelson-Somogyi reagent with the UV-Vis spectrophotometric method. The test was carried out by making a series of concentrations of ethanol extract of kopasanda leaves (Chromolaena odorata L.), namely 5, 10, 15, 20, 25 and 30 ppm using a UV-Vis spectrophotometer measured at a maximum wavelength of 749 nm. From the results of testing the antidiabetic potential of kopasanda leaves (Chromolaena odorata L.) in vitro, it was found that the equation y = 1.5986x + 38.183 with a correlation coefficient (r) = 0.9775 and an EC50 value of 7.3920 µg/mL showed that the leaf sample Kopasanda has potential as an antidiabetic
SAMPUL AS-SYIFAA JURNAL FARMASI 16.2 (2024) AS-SYIFAA JURNAL FARMASI 16.2 (2024), SAMPUL
As-Syifaa Jurnal Farmasi Vol 16, No 2 (2024): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v16i2.1277

Abstract

PENGUJIAN AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN BAWANG DAYAK (Eleutherine palmifolia (L.) Merr) TERHADAP BAKTERI PENYEBAB INFEKSI SALURAN PENCERNAAN MENGGUNAKAN METODE DIFUSI AGAR Fitriana, Fitriana; Asmaliani, Ira; Ar Ridwan, Yuki Ayumi
As-Syifaa Jurnal Farmasi Vol 16, No 2 (2024): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v16i2.1180

Abstract

Dayak onion leaves (Eleutherine palmifolia (L.) Merr) possess various biological activities, including antibiotic, antiviral, anti-inflammatory, and antibacterial properties, attributed to their secondary metabolites such as flavonoids, saponins, tannins, and phenolics. This study aimed to determine the antibacterial activity of ethanol extract from Dayak onion leaves against gastrointestinal infection-causing bacteria. The research began with screening tests of ethanol extract at concentrations of 0.1%, 0.5%, and 1% against Escherichia coli, Shigella dysenteriae, Vibrio cholerae, and Salmonella typhi. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were determined using extract concentrations of 1%, 2%, 4%, 8%, and 16%. Antibacterial activity was evaluated using the agar diffusion method at concentrations of 5%, 10%, and 15%. Screening results indicated antibacterial activity at a 1% concentration against all tested bacteria. The MIC value for all bacteria was 2%, while the MBC was 1% for Vibrio cholerae and 2% for Escherichia coli, Salmonella typhi, and Shigella dysenteriae. The agar diffusion method revealed the largest inhibition zones at a 15% concentration, with diameters of 10.23 mm for E. coli, 10.31 mm for S. dysenteriae, 11.07 mm for V. cholerae, and 11.32 mm for S. typhi. These findings indicate the potential of ethanol extract from Dayak onion leaves as an antibacterial agent.
EFEK EKSTRAK DAGING BUAH PALA (Myristica fragrans Houtt.) TERHADAP HISTOPATOLOGI PANKREAS TIKUS PUTIH (Rattus norvegicus) DIABETES Handayani, Sri Windi; S. Somadayo, Nur Asma; Fiskia, Ermalyanti; Nur, Amran
As-Syifaa Jurnal Farmasi Vol 16, No 2 (2024): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v16i2.1202

Abstract

Diabetes mellitus is a severe and persistent illness caused by insufficient production of insulin, a hormone responsible for regulating blood glucose levels, by the pancreas. Diabetes mellitus is a significant public health issue, and its incidence is expected to rise over the next several decades. This study aims to investigate the impact of nutmeg (Myristica fragrans Houtt) pulp extract on the pancreatic histopathology of diabetic white rats (Rattus novergicus). According to research findings, a dose of 100 mg/kgBW of nutmeg pulp extract has been found to effectively lower blood sugar levels without causing harm to the pancreas. On the other hand, doses of 200 mg/kgBW and 300 mg/kgBW of nutmeg pulp extract can drop blood sugar levels, but they have certain side effects. cause harm to the pancreas organ
DAFTAR ISI AS-SYIFAA JURNAL FARMASI 16.2 (2024) ISI, DAFTAR
As-Syifaa Jurnal Farmasi Vol 16, No 2 (2024): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v16i2.1278

Abstract

Page 38 of 40 | Total Record : 397

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