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Rachmat Kosman
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As-syifaa Jurnal Farmasi
Published by Universitas Muslim Indonesia
ISSN : 20854714     EISSN : 25029444     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology
As-Syifaa Jurnal Farmasi receives manuscripts in Indonesian Language (Bahasa Indonesia) with abstracts in bilingual, both Indonesian and English. We’re open for various fields such as: Pharmacology and Toxicology, Pharmaceutical Microbiology and Biotechnology, Herbal Medicines, Pharmaceutics, Pharmaceutical Chemistry, Drug Discovery, Pharmacokinetics, Pharmaceutical Biology, Community and Clinical Pharmacy, Pharmaceutical Care.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 397 Documents
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EVALUASI PENERAPAN STANDAR PELAYANAN KEFARMASIAN PADA PUSKESMAS DI KOTA KUPANG PERIODE MARET SAMPAI DENGAN MEI TAHUN 2023 Panduwiguna, Ivans; Mbau, Yansen Marthen; Rahman, Reza Ismail Abdul
As-Syifaa Jurnal Farmasi Vol 16, No 2 (2024): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v16i2.1254

Abstract

Pharmaceutical services at community health centres (puskesmas) are integral to the implementation of health efforts in advancing the quality of health services and improving the quality of life of patients, which are carried out by pharmacists directly. This study was conducted at community health centres in the Kupang City area because there has been no previous research related to the evaluation of pharmaceutical services. The purpose of this study was to determine the suitability of the implementation of pharmaceutical service standards at community health centres in the Kupang City area with Permenkes No. 74 of 2016 as a guideline in performing pharmaceutical services at community health centres. This study used an observational method with a descriptive approach using a checklist sheet. This study was conducted in the period March 2023-May 2023. The study sample was 11 respondents from Puskesmas Alak, Puskesmas Bakunase, Puskesmas Kupang Kota, Puskesmas Manutapen, Puskesmas Naioni, Puskesmas Oebobo, Puskesmas Oepoi, Puskesmas Oesapa, Puskesmas Pasir Panjang, Puskesmas Penfui, Puskesmas Sikumana. The results showed that the suitability of pharmaceutical services at Puskesmas in the Kupang City area was in accordance with Permenkes No. 74 of 2016 with the results of the checklist sheet getting an average of 78% with a good category.
PENENTUAN NILAI SPF DARI EKTRAK ETANOL DAUN JAMBU AIR (Syzygium aqueum) DAN DAUN KERSEN (Muntingia calabura L.) Zulkarnain, Iskandar; Aztriana, Aztriana; Hasrawati, A; Jaya, Taufiq; Iksan, Muh.; Mirawati, Mirawati
As-Syifaa Jurnal Farmasi Vol 16, No 2 (2024): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v16i2.1141

Abstract

Skin is the outer part of the body that is directly exposed to the environment, especially sunlight such as ultraviolet radiation. The skin basically has a defense against the negative effects of UV radiation of sunlight. Excessive sun exposure to the skin can cause skin damage that is acute (fast) and chronic (long). One of the ways used to prevent these negative effects is to use suncreen with a high SPF value. Syzygium aqueum and Muntingia calabura L. are plants that can be utilized as natural sunscreen active ingredients due to the content of polyphenolic compounds and high antioxidant activity values in their leaves. The purpose of this study was to determine the SPF value of ethanol extracts of Syzygium aqueum and Muntingia calabura L. and its protection category. Determination of SPF value was carried out by UV-VIS spectrophotometric method at UV B wavelength (290-320 nm), then the absorbance value obtained was calculated into the Mansur mathematical equation. Determination of sunscreen protection category based on SPF value refers to the provisions of the Food Drug Administrations (FDA). The results showed that the highest SPF value of Syzygium aqueum was obtained at a concentration of 1000 ppm, namely 46.183 with ultra protection category and the highest SPF value of Muntingia calabura L. at a concentration of 1500 ppm, namely 47.975 with ultra protection protection category. Based on these results, Syzygium aqueum and Muntingia calabura L. have the potential to be developed as sunscreen active ingredients with ultra protection category.
OBSERVASI PENYIMPANAN OBAT DI APOTEK KIMIA FARMA ABIAN TUBUH PADA TAHUN 2023 Annisa, Janatul; Saputra, Yoga Dwi
As-Syifaa Jurnal Farmasi Vol 16, No 2 (2024): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v16i2.1238

Abstract

One of the place that offers health services is a pharmacy, especially leading to pharmaceutical practice. A series of drug treatment and storage is carried out by putting the medicine in a protected place. One of the factors that affecting the quality of medicine is how well it is stored. Objective of this study was to observe and assess the drug storage system of 7 different therapeutic classes at Kimia Farma Abian Tubuh Pharmacy with the aim of improve pharmaceutical services provided by pharmacies as stipulated in the Regulation of the Minister of Health of the Republic of Indonesia Minister of Health of the Republic of Indonesia Number 73 of 2016 and Regulation of the Minister of Health No. 9 of 2017 concerning Apothecaries. Health Minister Regulation No. 9 of 2017 concerning Pharmacies. Information gathering is carried out by direct perception of the system through in-depth interviews with pharmacists and observation sheets. The observation results show that the level of drug storage at Kimia Farma Abian Tubuh Pharmacy is “96.67% Very Good” (81-100%) which indicates that storage at the pharmacy has been Good” (81-100%) which shows that storage at the pharmacy is in accordance with the guidelines. according to the guidelines
UJI EFEK EPITELISASI EKSTRAK DAUN PALA (Myristica fragrans Houtt.) PADA TIKUS JANTAN Azhary, Nursyahidah; Wati, Aulia; Herman, Hendra; Kosman, Rachmat
As-Syifaa Jurnal Farmasi Vol 16, No 2 (2024): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v16i2.1143

Abstract

Burns are damage or loss of tissue that occurs due to exposure to a heat source such as fire, hot liquids or fats, steam, radiation, electric current, or chemicals. Purpose of the research This is to determine the effect and effective dose of the ethanol extract of nutmeg leaves (Myristica fragrans Houtt.) in accelerating the epithelialization process in burn wounds. This study used 15 animals mice were divided into five treatment groups, namely negative control group (Na-CMC), positive control group (lanaeloid), and three test groups that received the dosed extract different: 200 mg/kgBB, 400 mg/kgBB, and 600 mg/kgBB. Burns are induced using a plate heat at 100ºC for 2 seconds on the rat's back. Therapy given topically twice a day for 21 days. Wound area measurements were carried out on days 1, 3, 5, 7, 14, and 21. The research results were statistically tested using the One Way Anova test with the Bonferroni post hoc test. Results The research showed that the positive control group was not significantly different from the test extract group. Based on the research results, it can be concluded that the ethanol extract of nutmeg leaves (Myristica fragrans Houtt.) has an epithelialization effect on mice with an effective dose of 600 mg/kgBB
PEMANFAATAN BEKATUL SEBAGAI BAHAN DASAR MEDIA ALTERNATIF PERTUMBUHAN Aspergillus flavus Oktaviani, Lu’lu Tsaniyah; Hamtini, Hamtini ,; Patricia, Venny; Armal, Hadits Lissentya
As-Syifaa Jurnal Farmasi Vol 16, No 2 (2024): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v16i2.1268

Abstract

Microbiology is the science that studies very small organisms, one of which is fungi. Fungi can grow and develop in a medium that contains sufficient nutrients. To identify the type of fungus, a growth medium is needed. Growth media is a substance consisting of a mixture of nutrients that support the growth of fungi, so it is necessary to make alternative media, one of which is using rice bran. The nutritional content of rice bran is 49.4 g carbohydrates, 24.7 g dietary fiber, 21.3 g fat, 16.5 g protein, 80 mg calcium, 2.1 grams phosphorus, 0.9 grams magnesium and 0.4 mg riboflavin vitamin. This research aims to determine the use of rice bran as a basic ingredient for alternative growth media for Aspergillus flavus. This type of research is an experiment by inoculating the Aspergillus flavus fungus using the Triple dot method. Observations were carried out for 7 days macroscopically by observing the diameter of the Aspergillus flavus fungus. The research results showed that there was an increase in colony diameter on rice bran media with concentrations of 8%, 10%, 12% and SDA media as a control of 29.3 mm, 33.0 mm, 33.8 mm and 34.9 mm. The effective concentration for the growth of the fungus Aspergillus flavus is a concentration of 12%. Based on the test results, it can be concluded that alternative media made from rice bran can be used as a growth medium for the fungus Aspergillus flavus.
PEMANFAATAN EKSTRAK ETANOL 70% KULIT JERUK SIAM KINTAMANI (Citrus nobilis L.) SEBAGAI BAHAN AKTIF PADA SEDIAAN LOTION ANTIOKSIDAN Indraswari, Putu Ika Indah; Marangyana, I Gede Bagus Indra
As-Syifaa Jurnal Farmasi Vol 16, No 2 (2024): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v16i2.1239

Abstract

Kintamani Siam orange (Citrus nobilis L.) is the most dominant orange and has been successfully cultivated in Bali. Kintamani Siam orange peel can be used as a source of natural antioxidants. Antioxidants are substances needed by the body to neutralize free radicals and prevent damage caused by free radicals. This study aims to determine the comparison of antioxidant activity in 70% ethanol extract of Kintamani Siam orange peel through optimization of extraction methods: soxhletation and digestion, then optimizing the lotion formula with 3 comparisons of extract concentrations (2.5%, 5%, 7.5%). The next stage is to compare the physical and chemical properties of the lotion and the antioxidant activity it has. Based on the antioxidant activity test of 70% ethanol extract of Kintamani Siam orange peel, it shows that the extract from the digestion extraction results has antioxidant activity with a strong category. Then the test of the lotion: organoleptic tests, adhesion, spreadability, pH, and viscosity of the lotion preparation, showed that all formulas met all preparation requirements. Meanwhile, for the antioxidant activity test, the results showed that the lotion formula 3 preparation had the highest antioxidant activity with an IC50 of 138.52, which is in the medium category. It can be concluded that the lotion formula 3 preparation is the most optimal formula after the extract is formulated in the form of a antioxidant lotion.
PENENTUAN NILAI SPF DARI EKSTRAK ETANOL DAUN KELOR (Moringa oleifera Lam) DAN DAUN KEMANGI (Ocimum basilicum L.) Mirawati, Mirawati; Purnamasari M, Vina; Harliman, Isrhopana Kinana; Sahira, Sahira; Bade, Iskandar Zulkarnain Mahmud; Hasrawati, A.; Haq, Nasrul
As-Syifaa Jurnal Farmasi Vol 17, No 1 (2025): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v17i1.1144

Abstract

Excessive exposure to ultraviolet (UV) radiation can lead to various skin issues, ranging from premature aging to an increased risk of skin cancer. As a result, the exploration of natural ingredients for UV protection has gained growing attention in cosmetic research. This study aims to evaluate the UV-absorbing potential of ethanolic extracts from Moringa oleifera Lam leaves and Ocimum basilicum L. leaves by determining their Sun Protection Factor (SPF) values. Using spectrophotometric analysis across different concentrations, both extracts demonstrated significant potential as natural sunscreen agents. At a concentration of 1500 ppm, the highest SPF values were recorded at 45.683 for Moringa oleifera Lam and 47.037 for Ocimum basilicum L. These findings highlight the promising potential of both plant extracts as active ingredients in sun-protective skincare formulations
AKTIVITAS ANTIBAKTERI EKSTRAK FERMENTAT ISOLAT FUNGI ENDOFIT KODE IFAZ-6 DARI AKAR BIDARA (Ziziphus mauritiana Lam.) TERHADAP BAKTERI Streptococcus mutans Fitriana, Fitriana; Amirah, Sitti; Rahman, Safriani; Charawati, Nurul Mega
As-Syifaa Jurnal Farmasi Vol 17, No 1 (2025): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v17i1.1338

Abstract

Endophytic fungi are microorganisms that reside within plant tissues and are known to produce secondary metabolites with antibacterial potential. This study aimed to evaluate the antibacterial activity of the fermented extract of the endophytic fungal isolate IFAZ-6, derived from the roots of Ziziphus mauritiana Lam. (bidara), against Streptococcus mutans. The isolate was fermented for 21 days and extracted using ethyl acetate. The extract was tested for antibacterial activity using Minimum Inhibitory Concentration (MIC) at concentrations ranging from 0.2% to 25.6%, Minimum Bactericidal Concentration (MBC) from 3.2% to 25.6%, and agar diffusion assay at concentrations of 8%, 12%, and 16%. Inhibition zone diameters were analyzed statistically using the Kruskal–Wallis test followed by the Mann–Whitney post hoc test to assess differences between concentration groups. The results showed an MIC value of 3.2% and an MBC of 6.4%. The agar diffusion assay revealed a maximum inhibition zone diameter of 9.86 mm at 16% concentration, with statistically significant differences between concentrations (p < 0.05). These findings suggest that the fermented extract of IFAZ-6 possesses antibacterial activity against S. mutans, although its efficacy remains lower than that of the positive control, chloramphenicol
DAFTAR ISI AS-SYIFAA JURNAL FARMASI 17.1 (2025) ISI, DAFTAR
As-Syifaa Jurnal Farmasi Vol 17, No 1 (2025): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v17i1.1364

Abstract

PENGARUH EDUKASI PASIEN BERBASIS VIDEO EDUKASI TERHADAP KEPATUHAN PASIEN DIABETES TIPE 2 DI PUSKESMAS PASAR SIMPANG, LAMPUNG Bangsawan, Tasya Okta Permata; Ghozali, Muhammad Thesa
As-Syifaa Jurnal Farmasi Vol 17, No 1 (2025): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v17i1.1296

Abstract

Diabetes mellitus (DM) is a chronic metabolic disorder characterized by persistent hyperglycaemia due to ineffective insulin use. In Indonesia, DM is a leading non-communicable disease. Medication adherence plays a critical role in managing DM, yet barriers such as long treatment regimens and limited patient-provider communication often hinder adherence. This study evaluated the effectiveness of a video-based digital intervention in improving medication adherence among DM patients at Public Health Center of Pasar Simpang in Kota Agung Timur, Tanggamus Regency. The study employed a cross-sectional design with 62 respondents divided into control and experimental groups. The intervention involved educational videos shared via WhatsApp. Adherence was assessed using the MMAS-8 (Morisky Medication Adherence Scale). Results revealed that adherence levels significantly improved in the experimental group post-intervention. The pre-test MMAS-8 mean score was 11.23±1.26, increasing to 13.97±1.33 post-intervention, with a mean difference of 2.74 (p = 0.000). In contrast, the control group showed no significant change, with pre- and post-test mean scores of 12.55±1.55 and 12.90±1.42, respectively (p = 0.315). Overall, 79% of respondents demonstrated good adherence, with significant improvements noted in the intervention group. These findings highlight the potential of video-based digital interventions in enhancing adherence among DM patients, providing valuable insights into diabetes care.

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