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Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan

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Published by Universitas Pembangunan Nasional Veteran Jakarta

ISSN : 02163438 EISSN : 26211122 DOI : -

Core Subject : Health,

Health Professions Medicine & Pharmacology

Arjuna Subject : -

Articles 244 Documents

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INSIDENSI KHOLANGITIS KRONIK SEBAGAI MANIFESTASI EKSTRAINTESTINAL PENDERITA IBD DI RSPAD GATOT SOEBROTO JAKARTA PUSAT Syafruddin ARL; Ruswhandi Martamala
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 11, No 1 (2017): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

IBD (Inflammatory Bowel Disease) as a disease of inflammation of chronic intestinal. The extraintestinal manifestation is predominantly in the form Pericholangitis, chronic cholitis or primary sclerosing cholangitis (PSC), which usually appear after a few years later from the pop-up cases of IBD with the incidence rate of 5%. Want to know the incidence rate of IBD and PSC in patients were undergoing colonoscopy at RSPAD GS since of March 1, 2016 until February 28, 2017. All patients were undergoing colonoscopy for one year included as a subject of research. Subjects sorted and selected on the findings of the colonoscopy as IBD and non-IBD. Data Cholitis chronic (KHK) is based on the findings of aspartate aminotransferase (AST) and total bilirubin elevated serum and serum albumin divided into groups of KHK-IBD or PSC, KHK-non-IBD, Non-KHK-IBD and Non- KHK-non-IBD. Correlation between the PSC and the PSC with IBD were tested statistically by Fisher, materials taken retrospective descriptive. Data PSC and IBD patients as follows: The incidence rate of IBD and PSC are 18.6% and 5.4%; Correlation PSC with extraintestinal manifestation of IBD acceptable expectation (p = 0.000); demographic data of IBD (30 patients) with male 62.4% (18 people), mean age was 50.6 years and incidence between 40 - 59 years old.

UJI EFEKTIVITAS EKSTRAK KUNYIT SEBAGAI ANTIBAKTERI DALAM PERTUMBUHAN Bacillus sp dan Shigella dysentriae SECARA IN VITRO Yuliati Yuliati
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 10, No 1 (2016): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Turmeric is a spice plants that acts as an antibacterial, because it contains a variety of compounds including curcumin and essential oil. Essential oils can be used as an antibacterial because it contains hydroxyl and carbonyl functional group which is phenols derivative. Te phenol derivatives will interact with the bacterial cell wall, then absorbed and penetrated into the bacterial cell, causing precipitation and denaturation of proteins, the result will lyse the bacterial cell membrane, while the antibacterial activity of curcuminis by inhibiting bacterial cell proliferation. Turmeric has launched a pharmacological eﬀect, lowering the fat content, asthma , hepatitis , anti- gall , anti- inﬂammatory , anti- diarrhea , and act as anti-inﬂammatory or anti-inﬂammatory. Turmeric has antibacterial properties of curcumin and essential oil that is capable of inhibiting the growth of bacteria that causes diarrhea and Shigelladysenteriae Bacillus sp. Tis study was conducted to determine the eﬀectiveness of turmeric extract on the growth of Bacillus sp and Shigella dysenteriae, with various concentrations of 15%, 30%, 50%, 75%, and 100% by the well diﬀusion method. Based on theinhibition zone measurement of bacteria Bacillus sp and Shigella dysenteriaethe results were weak category, for the bacteria Bacillus sp with a concentration of 15 % , 30 % , 50 % , 75 % , and 100 % with a diameter of 11 ; 12.3 ; 13 , 3 ; 13.7 ; 14.7 mm, while for the bacteria Shigella dysenteriae with the same concentration has a diameter of 10.3 ; 11.7 ; 12.3 ; 13.3 , and 14.7 mm. Te conclusion of the study is that the antibacterial activity of turmeric extract is more effective against the bacteria Bacillus spthan against bacteria Shigella dysenteriae, although the diﬀerence was not signifcant.

Hubungan Tingkat Stres Dengan Perilaku Berpacaran Pada Remaja Di SMA X Cawang Jakarta Timur Diah Ratnawati; Ismi Dyah Astari
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 13, No 1 (2019): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Stress is the psychic reaction of the body that arising from the presence of internal and external pressure. Date is an approach period between both opposite sex individuals, which is signed by personal introduction of their strength and weaknesses. Adolescent can not control themselves from pressure will trigger appear stress that can change behavior be like relationship. This study will conducted to see correlation between stress level by behaving dating in Senior High School X. Research was conducted to adolscents boys and girls with criteria ever or while correlation and age between 15-18 years. As the subject research will be sample is 236 students with distribution of male respondents 116 people and female respondents 120 people. Stress level variable was measured by used scale to standard anxiety and stress scale (DASS). While the measuring behavior to correlation of the researcher make a questionnaire with especially do it test the validity before the research. Kind of research was used quantitative research with method approach cross sectional and took sample do with techniq stratified random sampling. Based on research results found that the there is a correlation between stress level with dating behavior inadolescents Senior High School X Cawang. The results of this study is expected adolescents can take a positive value in dating behavior.

Gambaran Rerata Kadar Kalsium Dan Fosfor Pada Pasien Yang Menjalani Hemodialisis Di Rumah Sakit Anna Medika Bekasi Nur Annisya; Linda Armelia
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 12, No 1 (2018): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Background: Chronic Kidney Disease (CKD) is a pathophysiological process with a diverse etiology, resulting in slow progressive kidney function. Hemodialysis is used as a therapy to replace deteriorating renal function. PGK has high mortality and morbidity, because it can cause various complications, one of the complications of PGK is the regulation of mineral settings, especially calcium and phosphate. Methods: The type of research in this study is descriptive quantitative with cross sectional study design. The population in this study were PGK patients undergoing hemodialysis at Anna Medika Bekasi Hospital. Sample selection using simple random sampling technique with condition to fulfill inclusion criteria. Secondary data retrieval (medical record). Results: From 55 samples were 32 patients (58.2%) with hypocalcemia category, 14 patients (25.4%) with normal calcium level, 9 patients (16.4%) with hypercalcemia category, 10 patients (18.2%) with hypophosphatemia category, 4 patients (7.3% ) with normal phosphorus levels and 41 patients (74.5%) by category. Of 32 patients (58.2%) hypocalcemia and 41 (74.5%) hyperphosphatemia which decreased calcium along with a rise in phosphorus by 22 patients (40%). Conclusion: In this study it was found that patients were more likely to have hypocalcemia and hyperphosphatemia. Less than half the patients had decreased levels of calcium along with elevated levels of phosphorus.

Efek Antimikroba Ekstrak Lidah Buaya (Aloe vera) Terhadap Isolat Bakteri Penyebab Acne vulgaris Secara Invitro Meiskha Bahar; Hany Yusmaini
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 11, No 2 (2017): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Acne vulgaris adalah suatu kondisi inflamasi umum pada unit polisebaseus, ditandai dengan komedo, papul, pustul atau nodul. Penyakit kulit ini bukan merupakan penyakit yang berbahaya tetapi mempunyai dampak yang besar secara fisik maupun psikologik. Prinsip penanganan acne antara lain menurunkan populasi Propionibacterium acne dan menekan inflamasi. Dari penelitian sebelumnya ditemukan adanya mikroorganisme lainnya dalam lesi yang mungkin berperan selain Propionibacterium acne yaitu Staphylococcus aureus, S. epidermidis dan Pityrosporum ovale. Beberapa sumber melaporkan ada beberapa manfaat Aloe vera untuk kecantikan dan perawatan kulit. Aloe vera juga digunakan secara eksternal untuk mengobati berbagai kondisi kulit seperti luka, nyeri dan menekan proses inflamasi. Penelitian ini dilakukan untuk mengetahui efek antimikroba ekstrak Aloe vera konsentrasi 25%,50% dan 75% terhadap isolat bakteri penyebab Acne vulgaris secara invitro dengan menggunakan metode difusi. Sebelum pengujian dilakukan isolasi dan identifikasi bakteri dari lesi. Bakteri yang ditemukan dari lesi penderita tergolong bakteri golongan Gram positif yaitu Staphylococcus aureus dan Propionibacterium acne. Hasil uji One-way Anova menunjukan terdapat perbedaan bermakna efektivitas ekstrak lidah buaya terhadap S.aureus dan P.acne. Uji Post Hoc terhadap S.aureus menunjukan terdapat perbedaan bermakna ELB 25%, 50% dan 75% dengan kontrol (+) dan kontrol (-), tidak terdapat perbedaan bermakna antara ELB 25% dengan 50% dan 50% dengan 75%. Sedangkan antara 25% - 75% berbeda bermakna. Sedangkan Uji Post Hoc terhadap P.acne menunjukan bahwa tidak terdapat perbedaan bermakna antara ELB 25%, 50% dan 75% dengan kontrol positif. Kesimpulan : Ekstrak Lidah Buaya (Aloe vera) mempunyai efek antimikroba terhadap isolat bakteri penyebab Acne vulgaris yaitu Propionibacterium acne dan Staphylococcus aureus pada konsentrasi 25%, 50% dan 75% secara invitro.

UJI EFEKTIVITAS ANTIBAKTERI EKSTRAK DAUN BINAHONG (Anredera cordifolia (Ten.) Steenis) TERHADAP ISOLAT BAKTERI Escherichia coli JAJANAN CILOK SECARA IN VITRO DENGAN METODE DIFUSI Fadel Abima; Meiskha Bahar; Aulia Chairani
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 11, No 1 (2017): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Diarrhea is still one of the world’s major health problem especially in developing country. Foods and beverages contaminated by microorganism become the risk factor of diarrhea, including Escherichia coli (E. coli). One of the curative effort that can be done is to utilise the secondary metabolite compounds contained in binahong leaf (Anredera cordifolia (Ten.) Steenis). This study used true experimental method. The sample was binahong leaf extract with concentration of 25%, 50, and 75% using diffusion method (Kirby-Bauer) on doublelayered Mueller Hinton Agar (MHA) (base layer and seed layer) in order to measure the growth inhibition zone around the cylinder plate. The amount of population on this study was 24 isolations of E. coli. The repetition of each treatment group was counted by Federer formula. The result analyzed using Kruskal-Wallis test and showed that there was difference on binahong leaf extract effectiveness (p < 0,05), as well as on post hoc analysis using MannWhitney test showed that there was significant difference at concentration of 25%,50%, and 75%. (p < 0,001). This shows that there is a significant differences in the concentration of binahong leaf extract.

Pengaruh Faktor Determinan terhadap Hasil Terapi Hipertensi Pasien pada Tiga Puskesmas di Jakarta Pusat Andam Dewi Pertiwi; Prih Sarnianto; Hesty Utami Ramadaniati
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 13, No 2 (2019): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Hypertension has been known as risk factor of cardiovascular diseases necessitating the good control of blood pressure. The evident also shows the increased number of uncontrolled hypertensive patients. This study aimed to identify the determinants of controlled blood pressure in primary health centre hypertensive patients. The benefits of this research is to educated to public about factors that influence hypertension controlled. This research lasted for five months was conducted through patient interview of respondents meeting inclusion criteria in three primary health centres/PHC (PHC Menteng, PHC Tanah Abang, and PHC Johar Baru). Some data of the interview were validated by reviewing patient’s medical record. There were 26 factors used to analyse the determinants which included sociodemographic, biophysiology, dietary consumption patterns, use of hormonal contraceptives, physical activity, and stress). The result of multivariate regression analysis revealed two significant determinants, namely the presence of cardiovascular diseases (odd ratio/OR = 0,091, P-value = 0,004) and physical activity (OR = 10,647, P-value = 0,002). Patients with history of cardiovascular disease had 10,99 times risk to experience uncontrolled hypertension compared with those with no history of the disease. In addition, patients with routine physical activity at least 5 days/week (150 minutes/week) were 10,647 times to have controlled blood pressured as opposed to their counterpants.

Low analysis of community interest maintenance in Central Health Center Sukmajaya Kota Depok Provinsi Jawa Barat Gabe Gusmi Aprilla
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 14, No 1 (2020): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

According to the recapitulation of the utilization of Community Health Center inpatient services in Depok in 2016-2018, it was very low. The results of an initial survey in October 2018 conducted by Community Heath Center researchers who only served inpatients in only 3 districts, while 1 sub-district had not served general inpatients since one year ago. Of the three sub-districts, only 1 sub-district has inpatients, while others sometimes do not have an in-patient visit within one month. Sukmajaya Community Health Center was appointed to serve general inpatient care, basic neonatal obstetric services and care for malnourished children. Because of the low number of inpatient visits in the city of Depok, the researchers were interested in knowing the strengths and weaknesses as well as the opportunities and threats of the Sukmajaya Community Health Center. This study used a qualitative method conducted in February 2020 with in-depth interviews using interview guidelines and voice recording devices. Interviews were conducted with the Head of the Community Health Center, Head of Administration, Responsible for Inpatients, Doctors and Nurses. As a result, Sukmajaya Community Health Center was unable to compete with Private Hospitals because private hospitals had better health personnel and infrastructure than Sukmajaya Community Health Center. Besides that, the number of private hospitals in the city of Depok is large and the location is easy to reach, so people prefer hospitals with more convenient facilities.

Risk factors and costs of household perspectives in hemodialysis patients on Hospital Of Bhayangkara Tk. I. R. Said Sukanto Anggelina Aprilia Pangalila; Prih Sarnianto; Shirly Kumala
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 14, No 1 (2020): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

The incidence and prevalence of chronic kidney disease (CKD) patients in Indonesia is increasing every year. In the promotion of health promotion and prevention efforts, data related to risk factors and cost analysis are needed from the perspective of patients and / or families related to CKD treatment that requires replacement therapy for kidney function (Hemodialysis / HD). CKD patients undergo HD therapy generally twice a week, making it a relatively large burden on them. This study aims to determine the risk factors for CKD in hemodialysis patients at Bhayangkara Hospital Tk. I R. Said Sukanto and the impact of the cost of HD therapy from a household perspective. In an observational study with this case control method. Primary data was taken through interviews using a structured questionnaire with 100 HD patients (cases) and 100 patients from other poly (control), cross sectional. Risk factor analysis was carried out by logistic regression (p <0.05) and cost analysis using the accounting method. The results showed that in terms of socio-demography, ages above 40-49 years had a risk of 32.7 times and ≥ 50 years had a risk of 17.9 times having CKD compared to <30 years of age with an education level ≤ SD-SMA at risk 16.9 times affected by CKD from the academy / university group, and the income of Rp. 2,000,000 - Rp. 4,000,000 has a risk of 8.4 times being affected by CKD from income groups> Rp. 6,000,000. In terms of biophysiology, hypertension, diabetes and anemia had a risk of 516 times, 54 times and 272 times the effect of CKD. The habit of consuming Chinese and Western herbs increases the risk of developing CKD up to 10.9 times. The cost of the household perspective issued by the patient includes a meal cost of Rp360,000, transportation costs Rp.320,000 and drugs and multivitamins Rp250,000. The potential loss of productivity reaches Rp1,241,904 per patient per month.

Effectivity of the jackfruit leaves infusion (Artocarpus heterophyllus l.) as a larvacide to the mortality rate of Aedes aegypti larva Fina Alvia Rahma; Endang Mahati; R.A. Kisdjamiatun RMD; Ryan Halleyantoro
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 14, No 1 (2020): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Larval stage control using temephos, a chemical larvicide powder, was not completely safe. WHO recommended to use biological controls. Jackfruit leaves which contain saponins, flavonoids, and tannins can be used as alternate. This study was conducted to determine the effectivity of jackfruit leaves (Artocarpus heterophyllus L.) infusion on the mortality of Aedes aegypti larvae using post test only control group design. 600 of Aedes aegypti larvae were divided into 1 control group and 5 experiment groups that consist jackfruit leaves infusion concentrations of 4%, 8%, 12%, 16%, 20% with four times replication. The mortality of larvae was observed every 8 hours to 48 hours. The LC50 and LT50 were obtained by probit analysis were 3.842% and 2.150 hours. In the repeated Kruskal-Wallis test and Mann-Whitney, there were significant differences (p<0.05) in the mortality of Aedes aegypti larvae that died based on differences in the concentration of jackfruit leaf infusion. In the Spearman test, there were significant correlations (p<0.05) between the concentration of jackfruit leaves infusion and the mortality of Aedes aegypti larvae and the death rate of Aedes aegypti larvae. The results of the study are expected to be alternatives to chemical larvicides commonly used by the community.

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