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Majalah Kedokteran Nusantara The Journal Of Medical School
Published by Universitas Sumatera Utara
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
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Articles 181 Documents
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Profil Kadar Glukosa Darah pada Pasien Skin Tag Riana Miranda Sinaga
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 51, No 4 (2018): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

Introduction Skin tag (acrochordon) is benign tumor of connective tissue in the dermis of the most frequently encountered. Skin tag have a relationship with glucose metabolism disorders, especially diabetes mellitus and insulin resistance. Increased fasting blood glucose levels with polyuri, polydipsy and polyphagy one of the criteria for diagnosis of diabetes mellitus.Methods This study is a descriptive study with cross -sectional design involving 32 patients skin tag. Diagnosis of skin tag is made based on history, clinical examination. Then the patient's blood sample for examination of fasting blood glucose levels. Test results are presented in the form of descriptive data.Results In this study the majority of 27 patient skin tag (84.40%) had normal fasting blood glucose levels.  Conclusion :  Patients with skin tag generally have a normal fasting blood sugar levels.Keywords skin tag, fasting blood glucose levels, characteristic. AbstrakPendahuluan Skin tag (acrochordon) adalah tumor jinak jaringan konektif pada dermis yang paling sering dijumpai. Skin tag mempunyai hubungan dengan gangguan metabolisme glukosa terutama penyakit diabetes mellitus dan resistensi insulin. Peningkatan kadar glukosa darah puasa disertai poliuri, polidipsi, polifagi merupakan salah satu kriteria untuk menegakkan diagnosis penyakit diabetes mellitus. Peningkatan kadar glukosa darah diduga dapat terjadi pada pasien skin tag.Metode Penelitian inimerupakan suatu studi deskriptif dengan rancangan potong lintang (cross sectional) yang melibatkan 32 pasien skin tag. Diagnosis skin tag ditegakkan berdasarkan anamnesis dan pemeriksaan klinis. Kemudian pada pasien dilakukan pengambilan sampel darah untuk pemeriksaan kadar glukosa darah puasa. Hasil pemeriksaan disajikan dalam bentuk data deskriptif.Hasil Pada penelitian ini didapati mayoritas pasien skin tak 27 orang (84.40%) mempunyai kadar glukosa darah puasa normal.Simpulan Pasien skin tag  umumnya mempunyai kadar gula darah puasa normal.Kata kunci skin tag ,kadar glukosa darah puasa, karakteristik.
Hubungan antara Kombinasi Hemodialisis/Hemoperfusi dengan Total Body Water, Extra Cellular Water dan Intra Cellular Water Pasien Hemodialisis Reguler Faisal Sinurat
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 51, No 4 (2018): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

Introduction Clinical application of hemoperfusion combination with hemodialysis (HD/HP) demonstrated the optimal clearance of molecular uremic toxins. Kidney Disease Outcomes Quality Initiative (KDOQI) recommends assessment nutritional status of regular hemodialysis patients with a combination of valid assessment tools, such as 7-point SGA (Subjective Global Assessment) and albumin. This study is aimed to determine correlation between the combination of HD/HP with the nutritional status of regular hemodialysis patients.Methods This prospective cohort study from December 2013 to March 2014 on 20 regular hemodialysis patient and do history, measurements of height, weight, body mass index, nutritional status assessment by 7-point SGA and examination of serum albumin.Results At the end of observation, 20 subjects were observed one subject out of the study. There is a significant difference between the mean of score 7-point SGA before and after combination hemodialysis/hemoperfusion (p<0.05). There is a significant difference between the mean albumin before and after combination Albumin HD / HP first (p<0.05). There are differences in body mass index (BMI) after combination by sex (p<0.05). There is a strong relationship between the 7-point SGA with BMI after combination (r=0.636, p<0.01).Conclusion The combination of HD / HP is good clinical application for the treatment of malnutrition in regular hemodialysis patients. Regular assessment of nutritional status of regular hemodialysis patients is necessary, with a combination of a valid assessment tool (7-point SGA, albumin) is expected to help decrease morbidity and mortality.Keywords Hemodialysis, haemoperfusion, BIA, TBW, ECW, ICW AbstrakPendahuluan Dalam keadaan normal keseimbangan volume cairan tubuh intra dan ekstra seluler dipertahankan tetap konstan oleh ginjal. Aplikasi klinis kombinasi hemodialisis dengan hemoperfusi (HD/HP) menunjukkan tingkat efektifitas pembersihan molekul racun uremik yang optimal, terutama toksin dengan berat molekul menengah dan berat molekul besar pada pasien-pasien hemodialisis reguler. Penelitian ini bertujuan untuk mengetahui hubungan antara kombinasi hemodialisis / hemoperfusi dengan TBW, ECW, ICW pada BIA pada pasien hemodialis regulerMetode Penelitian kohort prospektif dari bulan Desember 2013 hingga Maret 2014 terhadap 20 pasien hemodialisis reguler dan dilakukan anamnesis, pengukuran tinggi badan, berat badan, indeks massa tubuh, penilaian status cairan tubuh dengan menggunakan alat BIA.Hasil Dari 20 subjek yang diamati 1 subjek keluar dari penelitian. Terdapat perbedaan bermakna antara rerata skor 7-point SGA sebelum dengan sesudah kombinasi Hemodialisis/Hemoperfusi (p<0.05). Terdapat perbedaan bermakna antara rerata albumin sebelum dan Albumin setelah kombinasi HD/HP pertama (p<0.05). Terdapat perbedaan Body Mass Index(BMI) setelah kombinasi berdasarkan jenis kelamin (p<0.05). Terdapat hubungan yang kuat antara 7-point SGA setelah kombinasi dengan BMI setelah kombinasi (r=0.636; p<0.01).Simpulan Kombinasi HD/HP merupakan aplikasi klinis yang cukup baik untuk penanganan malnutrisi pada pasien hemodialisis reguler. Penilaian rutin status nutrisi pasien hemodialisis reguler sangat diperlukan, dengan kombinasi alat penilaian yang valid  (7-point SGA,albumin) diharapkan dapat membantu menurunkan morbiditas dan mortalitas.Kata Kunci Hemodialisis, Hemoperfusi, BIA, TBW, ECW, ICW
Karakteristik penderita benda asing di esofagus di Rumah Sakit Umum Pusat H. Adam Malik Medan Januari 2006-Desember 2011 Suri Anita; Abdul Rachman Saragih; Linda Irwani Adenin; Ashri Yudhistira
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 45, No 2 (2012): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

Introduction : Foreign body ingestion and impaction in the esophagus constitutes an important cause of morbidity and mortality at any groups of age in worldwide.Objective : To determine the characteristic of esophageal foreign bodies in H. Adam Malik General Hospital Medan from January 2006 – December 2011.Methods : A descriptive study applying medical records of patients who were hospitalized for foreign body ingestion from January 2006 – December 2011.Result : One hundred and thirteen medical records was collected (71 males and 42 females) aged of 4 month – 75 years old, with mean 16.8 years old, were admitted with the diagnosis of esophageal foreign body. The most clinical symptoms was dysphagia 43.3% and odynophagia 28.2% from total symptoms. Anorganic was the most common foreign bodies 92% and organic 8%. The most common site of impaction were upper third 92.9%. The duration of impaction 44.2% was 6-24 hours. 92.9% with >24 hours length of time from diagnosed to the esophagoscopy procedure. Complication were noted in 5.4%. There was significant relation between age and type of foreign body and between age and location of impaction (P <0.05). Conclusion : The characteristic of esophageal foreign body were collected and found that there was significant relation between type of foreign body and age, site of impaction also.Keywords: foreign bodies; esophagus; esophagoscopy; characteristic
Perbandingan status koagulasi penderita stroke iskemik dengan non stroke Zainal Abdi; Rusli Dhanu; Savita Handayani; Dairion Gatot
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 45, No 2 (2012): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

Background: Thrombosis is one of causes increasing morbidity, disablement,and mortality in ischemic stroke’s patient. The basic mechanism of thrombosis is hypercoagulation state, so by finding it earlier can prevent and reduce thrombosis that cause ischemic stroke.Objective: This study to asses the event of hypercoagulation between ischemic stroke’s patient and non stroke. Methods: A total of 21 subjects with ischemic stroke’s patient and 21 subjects with non stroke entered into the study. All participants were examined for hemostatic parameters included prothrombin time (PT), INR, activated partial thromboplastin Time (aPTT), Fibrinogen, D-dimer. To compare the result of hemostatic both of groups were used t independent test if the distribution was normal or used Mann Whitney test if the distribution wasn’t normal. The result would be significant if P <0.05. Result: According to characteristic of population, it was found some variables significantly, included systolic blood pressure, diastolic blood pressure, INR, aPTT ratio and D-dimer. Hypercoagulation in ischemic stroke group was found 47.6% (n=10) and non hypercoagulation group was 52.4% (n=11) , but in non stroke group, hypercoagulation was found about 23.8% (n=5) and non hypercoagulation was 76.2% (n=16). According to statistical analysis there wasn’t significant hypercoagulation between ischemic stroke’s patient and non stroke (P >0.05).Conclusion: There isn’t significant hypercoagulation between ischemic stroke group with non stroke group. Keywords: ischemic stroke; hemostatic measurement; hypercoagulation; thrombosis
Karakteristik pasien skabies di SMF ilmu kesehatan kulit dan kelamin RSUP H. Adam Malik Medan periode Januari 2010-Desember 2012 Sufina F Nasution; Chairiyah Tanjung; Salia Lakswinar
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 45, No 3 (2012): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

Background: Scabies is a highly transmitted disease caused by Sarcoptes scabiei mite. The prevalence and complication which can occur has made scabies a significant public health problem in the developing countries. Objective : To find out the characteristics of scabies patients in the Dermatology and Venereology department at Haji Adam Malik general hospital Medan, in the period of January 2010-December 2012 on scabies epidemiology so that any measures for the improvement of handling patients in the future can be taken.Method : The research was a descriptive study, using secondary data analysis from medical records of scabies patients who visited the Dermatology and Venereology department at Haji Adam Malik general hospital Medan, in the period of January 2010-December 2012.Results : The characteristics of scabies patients were generally males (59.4%), 11 to 15 years old (28.3%), no/pre-school/elementary school graduates (47.1%), students (55.1%). There were 138 scabies patients who visited the Dermatology and Venereology department at Haji Adam Malik general hospital Medan, in the period of January 2010-December 2012.. The clinical charactheristics of scabies were all of the patients had subjective symptoms of pruritus (100%), the morphology of most of the lesion was papules (87.7%), and the location of most of the lesion was on legs (39.9%).Conclusion : The characteristics of scabies patients in the Dermatology and Venereology department at Haji Adam Malik general hospital Medan, were generally males, 11 to 15 years old, no/pre school/Elementary School graduates, students. There were 138 scabies patients who visited the Dermatology and Venereology department at Haji Adam Malik general hospital Medan, in the period of January 2010-December 2012.. The clinical charactheristics of scabies were all of the patients had subjective symptoms of pruritus, the morphology of most of the lesion was papules, and the location of most of the lesion was on legs.Keywords : scabies; characteristics
Gambaran pewarnaan imunohistokimia S100 pada meningioma di Rumah Sakit Umum Pusat H. Adam Malik Medan Gatot Aji Prihartomo; Abdul Gofar Sastrodiningrat; Iskandar Japardi; Sufida dr
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 46, No 1 (2013): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

Introduction: This study explores and describe the S100 immunohistochemical staining in meningioma.Methods: Sample specimens collected from patients who had meningioma undergo tumor removal surgery in the Adam Malik General Hospital Medan has previously been carried out basic hematoxylin eosin staining and was confirmed as meningioma by Epithelial Membrane Antigene (EMA) imunohystochemical staining. Representative slides are made of paraffin blocks and then performed S100 immunohistochemical staining. Staining intensity (SI) was score on scale 0-3 (from no staining to strong staining). Then viewed the characteristics of gender, age, location of tumor, World Health Organization (WHO) meningioma grade, histopathologictype, and tumor recurrence of meningioma specimens that express S100 immunohistochemical staining.Results: Thirty-one specimens of meningioma classified according to WHO criteria: benign 28/31 (90.3%), atypical 2/31 (6.5%) and anaplastic 1/31 (3.2%). These three criteria are classified according to histopathologic type. Meningothelial meningioma is the most widely histopathological types 17/31 (54.8%). Of the overall sample specimens, only 11/31 (35.5%) specimens expressed S100 immunohistochemical staining, the remaining 20/31 (64.5%) did not express. Of the 11 specimens that express S100 staining, benign meningiomas express 8/28 (28.6%) and fibroblastic meningiomas are the most strong S100 immunohistochemical staining( +3) between all the histopathologic type.Conclusion: In general, the results obtained from this study correspond by previous literature.Keyword: immunohistochemical staining; S100; meningioma
Hubungan kadar procalcitonin saat awal masuk pada pasien pneumonia komunitas terhadap kematian 30 hari Junita dr; EN Keliat; Alwinsyah Abidin
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 46, No 1 (2013): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

Intoduction : The assessment of level severity in patient with community acquired pneumonia (CAP) is very important to determine the next management of disease. Procalcitonin (PCT) is known as one of biomarker sepsis and infection. The application of PCT is known to be used in diagnosis, to help clinician to decide antibiotic treatment and to make prognosis. To determine the correlation between PCT and CURB-65 score in CAP patients at the early admission in hospital with 30-day mortality.Method : This was an cohort study. We had examined CAP subject with CURB-65(Confusion, Urea, Respiratory rate, Blood pressure, Age >65 years), PCT, other laboratory assessment and sputum and blood culture at the early admission at emergency room (ER). We had correlate the PCT levels with CURB-65 to determined prognostic utility of PCT and 30-day mortality. Results: In total, 57 subjects with CAP were enrolled in the study and subjects were follow-up for 30 days for survival. In 20 subjects (47.5%) who died during the follow-up,17 subjects (41.9%) died with PCT level • 0.25 ng/ml with severe CURB-65 score and 2 subjects (4.9%) with low-moderate CURB-65 score, but in PCT level >0.25 ng/ml with low-moderate CURB-65 score, 1 subject (6.3%) was died and no subject with severe CURB-65 score and total 30-day mortality were 20 subjects. We had found correlation between CURB-65 score and PCT level with 30-day mortality using pearson correlation (P = 0.0001). Conclusion : Procalcitonin is a biomarker of bacteria infection that has correlation with clinical scoring system CURB-65 and PCT level to determine 30-day mortality. PCT can be use to determine the prognosis in CAP at early admission.Keywords : community acquired pneumonia; CURB-65 score; procalcitonin; prognosis
Induksi platelet sebagai indikator komplikasi mikrovaskular pada penderita diabetes mellitus tipe 2 Yulia Ramdhani; Ozar Sanuddin; Santi Syafril
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 46, No 1 (2013): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

Introduction : Diabetes mellitus (DM) has been considered as a ‘‘prothrombotic state’ with enhanced platelet reactivity. Platelet activity and aggregation potential, which are essential components of thrombogenesis and atherosclerosis, can be conveniently estimated by measuring mean platelet volume (MPV) as part of whole blood count.This study was aimed to determine platelet indices [MPV, platelet distribution width (PDW) and platelet-large cell ratio (P-LCR)] between type 2 diabetics with and without microvascular complication.Methods : This study included 70 subjects with type 2 DM (40 with one or more microvascular complications) and 30 without microvascular complications. Anticoagulated blood (ethylene diamine tetracetic acid) was collected and analyzed in an automated blood cell counter for platelet count and indices.Results : In our study found the MPV, PDW and P-LCR were all significantly higher in subjects without microvascular complication compared to the subjects with microvascular complication [ 9.97 (SD 0.68) vs 9.81 (SD 0.76) fl ; 11.81 (SD 1.55) vs 11.44 (SD 1.50) fl ; 24.93 (SD 4.72) vs 23.79 (SD 4.88) % (P >0.05) ], respectively.Conclusion : There was no significant differences in platelet indices (MPV, PDW, and P-LCR) between subjects with and without microvascular complication.Keywords : mean platelet volume; platelet distribution width; platelet-large cell ratio; diabetes melitus; microvascular complication
Pengaturan cairan pada acute lung injury Monalisa Elizabeth; Munar Lubis; Yunnie Trisnawati
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 46, No 1 (2013): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

Mechanical ventilation is a life-saving technology for patients who develop acute lung injury (ALI) and investigators have conducted numerous investigations to determine the optimal support method and has been used for several decades. The incidence of ALI is quoted to be between 17 and 34 per 100,000 patients for year. Mechanical ventilation is indicated in patients with severe hypoxemia despite oxygen therapy, severe hypercapnia, or excessive work of breathing. Fluid management with the goal to obtain zero fluid balance in ARDS patients without shock or renal failure significantly increases the number of days without mechanical ventilation. Liberal and conservative fluid strategies are therefore complementary and should ideally follow each other in time in the same patient whose hemodynamic state progressively stabilizes.Key words : constipation; functional; children; medical therapy
Malignant transformation of sinonasal inverted papilloma Farhat dr
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 46, No 1 (2013): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Inverted papilloma is a benign epithelial growth in the underlying stroma of the nasal cavity and paranasal sinuses that is best known for its invasiveness, tendency to recur and association with malignancy.The most common presenting symptom is nasal obstruction. CT is the techniques of choice for pretreatment staging of neoplasms of the sinonasal tract. Complete surgical extirpation is the aim of treatment of choice for these tumor. A 66 years old man was admitted to ENT-HNS Department with main complaint mass in his left nasal cavity since 3 years and 7 months ago. In the beginning, mass as big as corn arised in his left nasal cavity. The mass enlarged in 7 months full fill left nasal cavity. Sinus paranasal CT Scan showed tumor of left nasal cavity extend to left maxillary sinus, left posterior ethmoidalis sinus and left frontalis sinusitis. He was underwent tumor extirpated with midfacial degloving on May 2008. Histopatology examination from biopsy and operation were inverted papilloma. Mass on left nasal cavity raised again 2 years and 8 months after operation. On examination, anterior rhinoscopy showed pinkish mass with ulceration full fill the left nasal cavity. Sinus paranasal CT Scan showed tumor of left nasal cavity extend to left maxillary sinus, left posterior ethmoidalis sinus and left frontalis sinusitis. Histopatology examination from biopsy was inverted papilloma. The tumor was extirpated with lateral rhinotomy. Histopatology examination was carsinoma cell squamous.We diagnosed the patient with sinonasal carcinoma.Keywords : inverted papiioma; sinonasal; malignant transformation

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