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Majalah Kedokteran Nusantara The Journal Of Medical School
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Core Subject : Health,
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Articles 181 Documents
Proporsi sifilis dini dan karakteristik wanita risiko tinggi di kabupaten Karo Rini Chrisna; Kristina Nadeak; Richard Hutapea
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 46, No 3 (2013): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Introduction : Syphilis is chronic sexually transmited infection caused by Treponema pallidum (T. pallidum). The incidence of syphilis was high that its became important to prevent the spread. Karo Regency was selected as location of this study because it is a tourist area and having some locations of prostitution.To find proportion of early syphilis and characteristic of high risk women in Karo regencyMethods : This is a cross sectional descriptive study on 29 high risk women with early syphilis in Sempajaya, Kuta Bangun and Tiga Binanga, Karo Regency. Diagnosis of early syphilis established based on anamnesis, physical examination and serologic tests VDRL/TPHA.Result : Three cases of early latent syphilis were found in Karo Regency which two cases of early latent syphilis were found in Sempajaya and one case of early latent syphilis was found in Tiga Binanga. Most of the case was found at the age of 26- 35 years old group (34.5%). The majority of the ethnic is Karo (37.8%). The majority of patient’s education is elementary school (37.9%). Early syphilis mostly suffered by commercial sex worker (51.7%) and married (72.4%).Conclusion : Proportion of early syphilis in Karo Regency was 10.3%. Proportion of early syphilis in Sempajaya was 6.9%. Proportion of early syphilis in Tiga Binanga was 3.2%. Proportion of early latent syphilis was 100%. The high risk women mostly found in group of 26-35 years old, the ethnic is Karo, elementary school graduate, commercial sex worker and have been married.Key words : proportion; early syphilis; high risk women
Karakteristik pioderma superfisialis pada bayi dan anak di SMF Ilmu Kesehatan Kulit dan Kelamin RSUP H. Adam Malik Medan periode Januari 2010 – Desember 2012 Rizky Kurniawan; Kristo A. Nababan; Salia Lakswinar
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 46, No 3 (2013): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Introductions : Superficial pyoderma is skin infection that located under stratum corneum until dermis or hair follicle.Objective : To identify the characteristic of superficial pyoderma in infants and children at Department of Dermatology and Venereology, H. Adam Malik General Hospital Medan, from period of January 2010 to December 2012. Methods : Retrospective study was carried out from medical records of superficial pyoderma patients in infants and children who had visited to Department of Dermatology and Venereology, H. Adam Malik General Hospital Medan, from period of 2010- 2012.Results : There were total 87 superficial pyoderma cases in infants and children, consist of 52.9% boys and 47.1% girls. Most common case was found in 1-5 years age group as much as 47.1%. The most common clinical presentation was bullous impetigo at 43.7%. The locations of superficial pyoderma lesions in infants and children showed relatively different annually. The locations of superficial pyoderma lesion in order from 2010-2012 are as followed; in the facial area was 31.0%, lower hands, armpit and lower limbs were 21.4% each, facial and armpit were 23.5% each. The treatment in infants and children usually using combination therapy depends on each clinical types.Conclusion: The most common case of superficial pyoderma in infants and children at Department of Dermatology and Venereology, H. Adam Malik General Hospital Medan were found in boys of 1-5 years age group. The most common clinical presentation was bullous impetigo. Each year showed different locations. The general treatment of superficial pyoderma in infants and children is topical antibiotics.Keywords : superficial pyoderma; retrospective study; characteristics
Profil ekspresi HER2 dan Ki67 pada berbagai kelompok usia penderita kanker payudara di RSUP H. Adam Malik Medan Santer dr; Kamal Basri Siregar; Suyatno dr
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 46, No 3 (2013): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Introductions : Breast cancer is commonly found in old age. Many genes had been reported to be involved in the carcinogenesis of breast carcinoma, such as p53, Ki67, cathepsin D, and HER2. Some studies reported that HER2 overexpression associated with age. Ki67 levels are associated with poor disease free survival.The aim of this study was to determine the level of overexpression of HER2 and Ki67 in the various age groups of breast cancer patients in H. Adam Malik Hospital Medan.Methods: This study was a descriptive cross sectional study, by examining Ki67 by immunohistochemistry in 40 paraffin blocks of breast cancer patients who had diagnosed in HER2 by immunohistochemistry examination. Specific cut off point of Ki67 was 14%.Results: 40 female samples had been studied. The majority of respondents are 35-50 years age group (45%). HER2 (+) were 12 samples and HER2 (-) were 28 samples. HER2 (+) was found in the 51-65 year age group of 6 sample (50%). Over expression of Ki67 were found in 28 samples and low expression in 12 samples. Over expression of Ki67 in the age group >65 years were 3 samples (100%).Conclusion: Over expression of HER2 and Ki67 found more in older age groups, based on the number of samples in each age group.Keywords: age; HER2 expression; Ki67 expression
Penilaian kualitas hidup pada anak penderita penyakit ginjal kronis Dicky Iskandar Nadeak; Rusdidjas dr; Rafita Ramayati; Oke Rina Ramayan; Rosmayanti S Siregar
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 46, No 3 (2013): The Journal of Medical School
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Penyakit ginjal kronis (PGK) oleh The National Kidney Foundation’s Kidney Disease Outcomes Quality Initiative (NKF KDOQI) didefinisikan sebagai suatu keadaan terjdinya kerusakan ginjal selama minimal 3 bulan dengan atau tanpa penurunan laju filtrasi glomerulus (LFG) atau LFG kurang dari 60 mL/menit per1.73m2 yang berlangsung selama 3 bulan dengan atau tanpa kerusakan ginjal. Penilaian kualitas hidup sangat penting dilakukan pada anak yang menderita PGK karena mempengaruhi gangguan pertumbuhan fisik, penghambatan perkembangan, terjadi gangguan kognitif, gangguan akademis, gangguan emosional, serta gangguan hubungan sosialnya. Beberapa studi telah melakukan penilaian kualitas hidup yang berhubungan dengan kesehatan pada anak penderita PGK dan mendapatkan bahwa kualitas hidup anak penderita PGK lebih rendah dibandingkan dengan anak sehat.Kata kunci : penyakit ginjal kronis; kualitas hidup; TECAVNER; laju filtrasi glomerulus
Hubungan kejadian gejala refluks gastroesofageal dengan konstipasi fungsional pada anak Herlina Loka; Atan Baas Sinuhaji; Supriatmo dr; Ade Rachmat Yudiyanto
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 46, No 3 (2013): The Journal of Medical School
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Constipation and gastroesophageal reflux are commonly found in the childhood. Delayed colonic transit time in children with functional constipation made the children experience gastroesophageal reflux symptoms such as regurgitation, vomiting, acid regurgitation, pyrosis, hiccup, belching, difficulty in swallowing and chronic cough.Keywords: gastroesophageal reflux; constipation; regurgitation; children
Perbandingan efektifitas pemberian imunisasi difteria satu kali, dua kali, dan tiga kali dengan penilaian titer antibodi pada anak Nurhandayani dr; Hendri Wijaya; Inke Nadia Diniyanti Lubis; Ayodhia Pitaloka Pasaribu; Syahril Pasaribu; Chairuddin P. Lubis
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 46, No 3 (2013): The Journal of Medical School
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Abstract: Current issue diphtheria immunization, pertussis, tetanus (DPT) is whether there is a difference of immunity and effectiveness of administration once, twice, three times to establish immunity. There is some suggestion that antibodies against an antigen titer of low does not indicate susceptibility to the disease or reverse the amount of high titer nothing to do with immunity to a particular disease.Keywords: immunization; diphtheria; pertussis; tetanus; antibody titers
Tembakau dan alkohol, manfaat dan mudaratnya Admar Jas
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 46, No 3 (2013): The Journal of Medical School
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Introduction : Tobacco come from crop leaf, tobacum L nicotiana ( fam. solanaceae) representing clump crop. Tobacco leaf which have been dried generally utilized for cigarette, as well as used for the sugi of, antiseptic and insectiside. The special contain of tobacco leaf is nicotine, nikotianin, tar, carbonitril, malic acid and tartaric acid. But from cigarette smoke will be obtained other additional substance like carbon monoxide and carbonitril. Nicotine and nicotianin are alkaloid which in body will stimulate autonom nervous system (ANS) and produced dopamine. The action of dopamine will distors cardiovascular system especially tachicardia, the high pressure of systole and euphoria. But happened high dose on the contrary that is hypotensi because nicotine and nikotianin will bind with nikotinik reseptor, so that happened hypotensi or vasodilatation. Where as carbon monoxide will bind haemoglobin to form the complex which don't have ability to bind oxygen. As a result is the physical become weak. Tar and of carbonitril can trigger the cancer of lung. The effect of tobacco especially nicotine and its derivate with alcohol will be happened an interaction and potentiation’s effect. Both of this compound will be accumulated in brain and lung so that will bother exhalation system and cardiovascular.Keywords : nicotine and it’s derivate; carbon monoxide; tar; from cigarette bothering of cardiovascular and lung syste
Penilaian alur luka untuk menentukan penyebab kematian Mistar Ritonga
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 46, No 3 (2013): The Journal of Medical School
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The gully injury is often used in explaning the macanisme of the death in establishing etiology of the death. The benefits of injury gully value, besides to determine the cause of death, at also to assist the investigation of the death in establishing the main actor when causing the victim dead, particularly is the incident was executed by many kind of fools and or actors. Keywords : trauma; injury gully; cause of death
The evaluation measurement of patellar height in Adam Malik Hospital M. Rizal Renaldi; Hafas Hanafiah
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 47, No 2 (2014): The Journal of Medical School
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Introduction : Patellar height is a parameter that is increasingly used, given that it expands the knowledge of knee biomechanics and the physiopathology of knee ailments. In the last few years, a variety of methods have been proposed as ways of defining the concept of patellar height, usually involving a ratio between radiographic parameters. The objective of this study was to analyze the methods for measuring patellar height in relation to inter-observer correlation, and correlation of the methods. Method : The study is cross-sectional design. The data were taken from population in Adam Malik Hospital in December 2013, which fulfill the inclusion criteria and had knee joint radiograph in lateral projection. The measurement of patellar height using insal-salvati (IS) method, caton-deschamps (CD) method, blackburne-peel (BP) method and plateau-patella angle (PPA) method. The radiographs were analyzed by four observer with different level of experience in the same time. The data was analyzed for the correlation of the methods and correlation of the inter-observer.Result : The study demonstrated that blackburne-peel correlated strongly with all three methods. Poorly degree of correlation occurred in caton deschamps method. Thus, the PPA and IS showed moderate correlation. The evaluation for interobserver correlation using interobserver kappa coefficient demonstrated high interobserver agreement for PPA followed by BP, CD, and IS.Conclusion : The best correlation between the inter-observer is using PPA method followed by BP. It is because plateau-patella angle spatially relates the patella to the tibial plateau or joint line, as does the blackburne-peel method. Keywords : patellar height; insal-salvati (IS); caton-deschamps (CD); blackburne-pell (BP); and plateau-patella angle (PPA).
Pengaruh kadar protein dan jumlah sel CSF terhadap angka kejadian malfungsi VP shunt di RS. H. Adam Malik Medan Indra Saputra; Rr. Suzy Indharty; A. Gofar Sastrodiningrat
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 47, No 2 (2014): The Journal of Medical School
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Background : Hydrocephalus is a disorder formation or absorption of fluid flow cerebrospinal. Number of cases of hydrocephalus in the world is quite high at around 0.5 -4 per 1000 live births while in Indonesia as much as 2-3 per 1000 live births. Ventriculoperitoneal shunt (VP shunt) is the main option in the treatment of hydrocephalus. One of the complications that occur in the installation of VP shunt was VP shunt malfunctions that happen as much as 25-40% especially in the first year after installation of VP shunt.Methods : The study was conducted on 169 hydrocephalus patients who performed the installation VP shunt in Haji Adam Malik Hospital Medan since January 2010 to December 2012. The data were analyzed using chi square and p values <0.05 were considered as significant.Results : In the 169 patients who performed the installation of VP shunt, 47 patients (27.8%) of them had VP shunt malfunction. Among the 47 patients who had malfunctions of VP shunt, 16 patients (40%) had shown increased of total cerebrospinal fluid protein and it had been statistically significant association between the incidence of VP shunt malfunction with cerebrospinal fluid protein levels (p = 0.049). While the examination of the number of cells in the cerebrospinal fluid of 47 patients who had VP shunt malfunctions, 14 patients (36%) had shown the increasing of number of cells in the cerebrospinal fluid and this indicates that the relationship of the incidence of VP shunt malfunction with the number of cells in the cerebrospinal fluid was not statistically significant (p =0.199).Conclusion : There is a significant correlation between cerebrospinal fluid protein levels with the incidence of VP shunt malfunction. While the number of cells in the cerebrospinal fluid showed no significant correlation with the incidence of VP shunt malfunctions.Keywords : Malfunction; VP shunt; protein; cel count; cerebrospinal fluid; Hydrocephalus

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