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Majalah Kedokteran Nusantara The Journal Of Medical School
Published by Universitas Sumatera Utara
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Arjuna Subject : -
Articles 181 Documents
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Interleukin-6 urin sebagai pemeriksaan cepat pielonefritis pada neonatus Nezman Nuri; Rafita Ramayati; Oke Rina Ramayani; Rosmayanti Syafriani Siregar; Beatrix Siregar
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 46, No 2 (2013): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

Pyelonephritis is a common infection to all children in all age groups, including the newborn. The diagnosis of urinary tract infection is established certainly by urine culture. Additional investigations can be done to help confirm the diagnosis, such as urinary interleukin-6. Increased number of urinary interleukin-6 is helpful to quickly confirm the occurrence of pyelonephritis. Keyword : pyelonephritis; neonates; urine culture; interleukin-6
Penanda infeksi bakteri pada pneumonia anak Wardah .; Nurjannah .; Bakhtiar .; Rini Savitri Daulay
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 46, No 2 (2013): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Pneumonia is the main health problem and the major causes of children’s death, particularly in children under five years old. Etiology of pneumonia are varried but it is very difficult to identify the etiology of pneumonia in children. The examination of lung’s secretory is very difficult to be performed in children. The examination of leucocyte, erythrocyte sedimentation rate, C-reactive protein and procalcitonin level can be used as bacterial infection’s marker to be treated with antibiotics. In addition, procalcitonin clinically proven more sensitive and spesific to identifying the infection caused by bacteria, compare to another marker.Keywords : pneumonia; children; marker; procalcitonin
Management of inverted papilloma with degloving approach Farhat dr
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 46, No 2 (2013): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

According to the World Health Organization, inverted papilloma is defined as a benign epithelial tumor composed of well-differentiated columnar or ciliated respiratory epithelium having variable squamous differentiation. A 62 years old man came into Adam Malik Hospital on April 19th, 2013 with complaint of unilateral nasal obstruction for 5 years. After examinations we diagnosed the patient with inverted papilloma and performed degloving approach to to removed the tumor dand the tumor removed intact succesfully. Inverted papilloma is one of the sinonasal papilomas subtype which aggresively treated because of a relatively high recurrence rate and potential for malignant transformation.Keywords : inverted papilloma; sinonasal; degloving
Hubungan raeseptor estrogen dengan Ki-67 labeling index pada meninagioma intrakranial Abdurrahman Mouza; Iskandar Japardi; Suzy Indharty
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 50, No 2 (2017): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

Introduction : Meningioma occurs more in women than men with ratio 2 : 1. Mitosis of meningioma is stimulatedbyfewgrowth factorsand one of itis estrogen. Expression of estrogen receptor on meningioma showsthat clinical meningioma has characteristic more aggressive. Proliferation Index can be measured by antibody of Mind Bomb (MIB-1) binding Ki-67 antigen. Ki-67 is showed on the cells which proliferating through cells cycle.Relation between estrogen receptor and cell proliferation is interesting because it has controversy.Method : This Study used Cross Sectional method for analising relation between estrogen receptor and Ki-67 in patients have been diagnosed meningioma. This study has been done at general hospital H. Adam Malik Medan and laboratorium of patologi anatomi at Murni Teguh hospital.This study did in Oktober-November 2013.Result : In this study is almost meningioma grade I stained Ki-67 not have mitosis with amount 13 sample (43.3%) or positive mitosis is 14 sample (45%). While immunohistochemistry staining of estrogen receptor on meningioma grade I has 25 negative sample (83.3%) and 14 positive sample (51.8%). All of grade I and II are negative.Relation of these staining was used Chi-Square with limit value p<0.05. This result is p=0.677 that shows no significance relation between estrogen receptor and labeling Index Ki-67.Conclusion : These histopatology have many frequents type that is 16 cases of meningothelial meningioma (53.3%), fibroblastic meningioma, and 4 cases transitional meningioma (13.3%). The result is no relation between estrogen receptor and Ki-67 with p=0.667 (p>0.05).Other results are no relation Ki-67 with age p=0.204 (p>0.05) and sex p=0.121 (p>0.05). Keywords : estrogen receptor, Ki-67, meningioma
Hubungan antara kadar hepcidin dan kadar soluble transferrin receptor pada •-thalassemia trait Anitawati dr; Adi Koesoema Aman; Ratna Akbari Ganie
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 50, No 2 (2017): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Introduction : Hepcidin plays important role in regulating ferrum circulation and ferrum toxicity in thalassemia patient. Soluble transferrin receptor(sTfR) is an ineffective eritropoetic measurement parameter which is more accurate. To find out correlation between Hepcidin and sTfR in •-thalassemia trait patientMethods : This is a cross sectional study which conducted on 28 patient with•-thalassemia trait who consulting in RSUP Haji Adam Malik Medan in March-May 2016. Analysis included full blood count, electrophoresis Hb, Hepcidin,and sTfR serum. Results : There was correlation between Hepcidin and sTfR serum level in •--thalassemia trait patient, this study showed strong correlation (r= 0.613). Statistical analysis found significant correlation between Hepcidin and sTfR level ( p = 0.001). Conclusion : This study showed strong correlation between Hepcidin and sTfR level in •-thalassemia trait patient. Keywords : •-thalassemia trait, Hepcidin, sTfR
Perubahan kadar albumin dan prealbumin etelah suplementasi ekstrak ikan gabus metode freeze dryer pada pasien sepsis Ahmad Fiza Putera; Achsanuddin Hanafie; Dadik Wahyu Wijaya
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 50, No 2 (2017): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Introduction : Septic is the second highest cause of death in Intensive Care Unit and 10 highest cause of death in the world overall. Mortality and Morbidity of sepsis in relation with hypoalbuminemia, with the number incidence 60-70%. The principal of nutritional management in septic patient is how to manage calories and high protein to balance the catabolic process. Extract of snakehead fish is the source of high protein in compare with other sources. The purpose of this study is to know the level of albumin and prealbumin after the sumplementation of extract of snakehead fish with the freezy dryer methode. Methodes : The Randomized Control Trial double blinded which done in Mei-June 2016 in Rumah Sakit Umum Pusat Haji Adam Malik Medan. The total of 38 Patients whose included in inclusive and exclusive criteria for this research. Level of albumin and preabulmin was measuring after the suplementation extract of snakehead fish with the methode of freezy dryer as suplementation of protein as a enteral nutrition in 3 days intervention. In a group with suplementation extract of snake head fish with the methode of freezy dryer increased the level of albumin 0.26 gr/dL (p<0.001) and the level of prealbumin 9.36 mg/dL (p<0.001). In difference with the group given placebo, the level of albumin decreased 0.32 gr/dL (p<0.001) and the decreased of prealbumin 4.58 mg/dL (p<0.001).Result : Extract of snakehead fish with the freezy dryer extraction could increase 0.26 mg/dL albumin level and 11.26 mg/dL prealbumin level.Conclussion : suplementation of snakehead fish with the freezy dryer methode could increase albumin and prealbumin level efectively.Keyword : additional protein intake, hypoalbuminemia, nutrition, sepsis
Perbedaan kadar interleukin-6 pada pasien dengan dan tanpa stenosis koroner signifikan Fatiah dr; Ratna Akbari Ganie; Andre Pasha Ketaren
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 50, No 2 (2017): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

Introduction : Coronary heart disease (CHD), characterized by coronary arteries stenosis, is the end result of atherosclerosis. Interleukin-6seems to be the key point in process of atherosclerosis.The aim of this study is to find out whether there is a difference between serum Interleukin-6 level in patients with and without significant coronary stenosis.Methods : A cross-sectional observational analytic study was performedto 34 patients with suspected CHD that underwent coronary angiographyin H.Adam Malik hospital, Medan from February- April 2016.Patients were divided into 2 groups, 17 patients with significant coronarystenosis and 17 patients without significant coronarystenosis.Serum Interleukin-6 level were measured.Results : The medianvalue of serum Interleukin-6 levelin patients with significant coronarystenosis was 14.7 pg/mLand patients without significant coronarystenosis was 12.62pg/mL. There was no significant difference between serum Interleukin-6 level in patients with and without significant coronary stenosis ( p=0.301).Conclusion : There was no significant difference between serum Interleukin-6 level in patients with and without significant coronary stenosis.Keywords : Interleukin-6, Atherosclerosis, CHD
Perbandingan akurasi diagnostik kriteria cornell product dengan kriteria sokolow lyon dalam menentukan hipertrofi ventrikel kiri pada pasien hipertensi obese di RSUP H. Adam Malik, Medan Muhammad Azhari; Rahmad Isnanta; Zainal Safri; Refli Hasan
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 50, No 2 (2017): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Introduction : LVH is an important cardiovascular risk factors in hypertensive patients.Accuracy of ECG criterias was relatively low in diagnosis LVH. Cornell product criteria are the criteria used in the diagnosis LVH in obesity because of easier application. The aim of this study was Determine the accuracy of the Cornell product and sokolow lyon in the detection of left ventricular hypertrophy in obese hypertensive patients at Adam Malik General Hospital.Methods : This cross sectional study from September to October 2015 on 61 cardiology policlinic patients and we did anamnesis, measurement of blood pressure, height, body weight, BMI, BSA, ECG and Echocardiography.Result : From61 patients admitted to cardiology policlinic, we found 34 male and 27 female. The result of echocardiography revealed 38 of hypertensive patients have LVH (62.3%). Sensitivity, specifity and accuracy of different ECG criteria for diagnosis LVH ranged from 31.6% (Cornell product and Romhilt estes) to 47.4% (Cornell Voltage), 65.2%(Cornell Voltage) to 95.8%(Sokolow Lyon), 50% (Cornell Product and Romhilt Estes)to 61.7% (Sokolow Lyon). Positive predictive value were ranged from 75% (Cornell & Romhilt Estes) to 92.9% (Sokolow Lyon) andNegative predictive value were ranged from 42.2%(Cornell Product and Romhilt estes) to 46.8% (Sokolow lyon).Conclusion :The accuracy of ECG criteria Cornell Product no better than lyon Sokolow criteria in terms of assessing LV hypertrophy in hypertensive patients with obesity.Key word : Leftventricular hypertrophy, Cornel product, sokolow lyon, hypertensive obese
Hubungan modifikasi kadar natrium dialisat dengan phase angle pada pasien hemodialisis reguler Nurfatimah Itoni Ritonga; Syafrizal Nasution; Abdurrahim Rasyid Lubis
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 50, No 2 (2017): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Introductions : Uncontrolled blood pressure and persistant overload extracelluler fluid caused by the positif balance of sodium and water, is the contributor of left venticular hipertrophy in hemodialytic patients and will influeate to cell integrity. Sodium dialysate level modification is one of the method to solve this matter. Phase angle is the method to examine the cell integrity in hemodialysis patients. The aim of this study was to determinethe correlation betweenmodifications of sodiumdialysatewith phase angle in regularhemodialysispatientsMethods : An experimental studydesignfromMay untilDecember 2014in28regularhemodialysis patients. By comparing phase angle at pre hemodialysis before and after sodium dialysate modificationResults : Of the 28 subjects, we found 16 male patients (57.1%) and female 12 patients (42.9%) with mean phase angle after sodium dialysate modification higher compare than before modification (5.83 vs 5.80). But there is no significant difference in statistic (p=0.145)Conclusion : There is no significant difference in phase angle between before and after sodium dialysate modification. Keywords : Hemodialysis, modificationof sodiumdialysate, phase angle.
Perbandingan kadar kreatinin darah antara penderita preeklampsia berat/eklamsia dengan kehamilan normal Rushakim Lubis; Ichwanul Adenin; M. Rhiza Z Tala
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 50, No 2 (2017): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Introduc : Comparison analysis blood level of creatinine in severe preeclampsia/eclampsia with normal pregnancy. This study is an observational analytic study with a cross-sectional study design to pregnant women in severe preeclampsia/eclampsia and pregnant women with normal blood pressure. .Results : In this study, which began in April 2014, 30 patients obtained eclampsia and severe preeclampsia. Characteristics of pregnant women with severe preeclampsia/eclampsia highest in the age group 20-35 years (41.7%). Based on the number of pregnancies, with gravid 1 is 25% the same as much as 25% gravida 2-3. History of education, which is the highest with low education (40 %), the highest number of ANC visit < 4 times as much as 35%. There is no significant difference in creatinine blood level between pregnancy in severe preeclampsia/ eclampsia with normal pregnancy, where the p value is worth < 0.605 (p> 0.05).Conclusions : There is no significant difference in creatinine blood level between pregnant mother in severe preeclampsia with normalapregnancy. .Keywords : Severe preeclampsia, Eclampsia, Creatinine

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