cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
-
Contact Email
-
Phone
-
Journal Mail Official
-
Editorial Address
-
Location
Kota medan,
Sumatera utara
INDONESIA
Buletin Farmatera
Published by Universitas Muhammadiyah Sumatera Utara
ISSN : 2528410X     EISSN : 2528410X     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Arjuna Subject : -
Articles 244 Documents
 19   20   21   22   23 
The Relationship Between Anthropometric Measurements and Low-Density Lipoprotein (LDL) Levels in Women Aged 30-50 Years Harahap, Shofiah Rahmah; Thristy, Isra
Buletin Farmatera Vol 10, No 1 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i1.24413

Abstract

Abstract: Nutritional status is known to influence low-density lipoprotein (LDL) levels. It can be assessed by measuring body mass index (BMI), waist circumference (WC), and mid-upper arm circumference (MUAC). Individuals with obesity are at greater risk of having elevated LDL levels compared to those with normal nutritional status. In women, hormonal changes, particularly during menopause, can affect lipid metabolism and contribute to higher LDL levels. This study aimed to examine the correlation between BMI, WC, and MUAC with LDL levels in women aged 30-50 years. This descriptive-analytical study used a cross-sectional design involving 38 females’ subjects aged 30-50 years old. Anthropometric measurements and LDL levels were recorded. Pearson’s correlation test was used for data analysis. The results showed a weak but statistically significant positive correlation between BMI and LDL (p = 0,034, r = 0,344), WC and LDL (p= 0,035, r=0,344), and MUAC and LDL (p = 0,046, r = 0,326). This study found a correlation between BMI, WC, and MUAC on LDL levels.
Resistance Training Has an Effect on Lowering Insulin Resistance Based on HOMA IR Examination in Poly Cystic Ovarian Syndrome (PCOS) Patients: Meta-Analysis Nasution, Muhammad Solih; Akbar, Aidil
Buletin Farmatera Vol 10, No 3 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i3.24468

Abstract

Abstract: Poly Cystic Ovarian Syndrome (PCOS) is a complex endocrine disorder that affects women of reproductive age. Insulin resistance, obesity, and hormonal imbalances are the main characteristics of this condition. Physical exercise, including weight training or resistance training , is suspected to be effective in lowering insulin resistance, but direct comparisons based on the results of the HOMA IR examination have not been carried out systematically. This meta-analysis aimed to evaluate the effectiveness of weight training in lowering insulin resistance based on the results of the HOMA IR examination in PCOS patients. Four clinical studies that met the inclusion criteria and included 87 women diagnosed with PCOS and 93 women without PCOS were analyzed for their insulin resistance conditions. Insulin resistance check parameters using the HOMA IR test. Statistical analysis using a fixed effect model with a paired t test. Overall, resistance training interventions  showed a negative effect on the difference in HOMA-IR between pre-test and post-test. The mean HOMA-IR score after the intervention was lower compared to the pre-intervention score. This suggests that resistance training can lower insulin resistance in PCOS patients. Resistance training can reduce insulin resistance in PCOS patients as measured by HOMA-IR examination. However, variations in results between studies suggest that the effects of resistance training on insulin resistance are not entirely uniform, depending on factors such as exercise intensity, duration, and characteristics of study participants.
The Relationship Between CT Value and Clinical Degree of Children With Covid-19 in RSU Bunda Thamrin Medan Siregar, Ifany Hafidzah; Airlangga, Eka
Buletin Farmatera Vol 10, No 2 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i2.24420

Abstract

Abtract : Coronavirus disease 2019 (COVID-19) is caused by Coronavirus 2 acute respiratory syndrome (SARS-CoV-2). COVID-19 has varied clinical manifestations, ranging from asymptomatic, mild, moderate, severe and critical. Diagnosis in COVID-19 patients can be established using RT-PCR. This study aims to determine the relationship between CT value and clinical degree of children with covid-19 in RSU Bunda Thamrin Medan.This type of research is an analytical observational study with a cross-sectional study. The number of samples in this study was 165 samples. Of the 165 pediatric patients diagnosed with COVID-19, 53 children (32.12%) were aged 5 years while 112 children (67.88%) were aged ≥ 5 years. Males were 97 children (58.79%) and girls were 68 (41.21%). The most common comorbid disease was obesity, which was 51 children (67.1%). Pediatric patients with asymptomatic symptoms 8 children (4.8%), 126 children (76.4%) with mild symptoms, 7 children (4.2%) with moderate symptoms, 23 children (13.9%) with severe symptoms and 1 child (0.6%) with critical symptoms. 143 children (86.67%) patients had CT Value values ≤ 29, 21 children (12.73%) patients with CT Value values of 30 – 37, and 1 child (0.6%) had CT Value values of 38 – 40.  In this study, it was found that there was a relationship between CT Value and the clinical degree of children with COVID-19.
Routine of Reading the Qur'an Related to Cognitive Function in Students of Muhammadiyah 01 Medan High School Mulya Hasibuan, Firza; Yunafri, Andri
Buletin Farmatera Vol 10, No 3 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i3.25273

Abstract

Abstract: The Qur'an is the word of Allah Subhanahu Wa Ta'ala, which was revealed to the Prophet Muhammad (peace and blessings of Allaah be upon him) to be conveyed to mankind, especially to the people of the Prophet, as a guide for the life of Muslims in the world. The habit of reading the Qur'an is a continuous intellectual activity, which is worship. The purpose of this study is to find out the relationship between the routine reading of the Qur'an and the ability of cognitive function, especially in intellectual intelligence. This study is a comparative analytical research of 2 unpaired groups. The research design used is a true experimental design with post post-test only control group design. The research subjects totalled 40 people who were selected by the purposive sampling method. The analysis data used an independent t-test. Based on the results of the Independent Sample T-Test, a significance value (p-value) of 0.000 (0.05) was obtained.. The sample that regularly read the Qur'an for 1 month had a superior IQ score of 9 people (23%), a high average of 10 people (25%), and an average of 1 person (2.50%). Meanwhile, those who do not regularly read the Qur'an for 1 month have an average IQ score of 17 people (42.50%), and a low average of 3 people (7%). There is a significant influence on cognitive function, especially intellectual intelligence, from reading the Qur'an regularly for 1 month.
Literature Review: Relationship Between Rubber Factory Pollution Exposure and Reactive Oxygen Species (ROS) Levels in Workers Pasaribu, Sumihar MR; Purba, Amril; Perangin-angin, Guntur; Siahaan, Jekson Martiar
Buletin Farmatera Vol 10, No 3 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i3.25610

Abstract

Abstract: Working in rubber factories exposes personnel to a cocktail of airborne contaminants—hydrogen sulfide, organic solvents, and fine dust—that jeopardise health over the long term. A key pathological response to such pollution is the upsurge in reactive oxygen species (ROS), which drives oxidative stress and underlies injury to cells, tissues, and organ systems. The present review compiles biomarker and mechanistic data showing how encounters with factory fumes correlate with elevated ROS levels in exposed workers. Cross-sectional surveys and laboratory experiments consistently report raised indicators such as malondialdehyde (MDA) and 8-hydroxy-2-deoxyguanosine (8-OHdG), establishing a robust link between airborne toxins and molecular damage. Genetic variants that weaken antioxidant enzymes further shape individual risk, reminding us that not every worker faces the same burden even under identical exposure conditions. Consequences typically affect the respiratory tract, heart, and metabolic pathways, reinforcing calls for stronger engineering controls, personal monitoring, and health surveillance in the plant. Early trials of antioxidant supplements show promise for damping ROS pathways, yet the field still lacks evidence-based protocols that tailor interventions to sources and dosages of pollution. By clarifying these oxidative processes, the review aims to guide regulators and industry managers in crafting rules that truly protect workers' lives and livelihoods
Effectiveness of Metformin in Management Latest Type 2 Diabetes Mellitus : A Literature Study Hariaji, Ilham
Buletin Farmatera Vol 10, No 2 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i2.26247

Abstract

Abstract: Diabetes mellitus type 2 (DMT2) is a chronic metabolic disease whose prevalence is increasing globally. Metformin remains a first-line therapy due to its effectiveness in lowering blood glucose and its good safety profile. This literature review analyzed 25 publications from the journal Scopus Q1 (2021–2025) that evaluated the effectiveness of metformin in monotherapy and combination therapy. The studies analyzed included randomized controlled clinical trials, meta-analyses, and cohort studies. Metformin showed an average HbA1c decrease of 1.0–1.5%. Combination with SGLT2 inhibitors and GLP-1 receptor agonists improves glycemic control and lowers cardiovascular risk. Anti-inflammatory and endothelial protective effects have also been reported. Metformin remains relevant as the primary therapy, but its effectiveness increases when combined with new agents and adapted to the characteristics of the patient. Metformin is effective in the management of current DMT2, especially in combination therapy and personalization approaches.
Determination of Height Based on Estimated Femur Length in Medan City Shella, Remuqita; Parinduri, Abdul Gafar
Buletin Farmatera Vol 10, No 3 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i3.24272

Abstract

Abstract : Identification checks are an important action to find out the identity of a person, other than living people, especially in the case of victims who have died or disappeared. The identification process used in the field of forensic anthropology is the anthropometric method, which measures one part of the body to determine the estimated height. The length of the inferior limbs has the most favorable correlation for human height. In this case, the femur is one of the parts of the body that is commonly used in height estimation. The femur section is the best parameter because it is in line with the anatomical structure of the body for the determination of height, which is useful in a clinical context. The researcher is interested in researching height based on femur length in FK UMSU students in the class of 2019. This research method is an analytical descriptive research with a cross-sectional design approach. The research subjects were 113 students of FK UMSU stambuk 2019, consisting of men and women who met the inclusion and exclusion criteria. Sampling technique using purposive sampling. The length of the femur has a correlation value that ranges from 0.382 to 0.534 (p≤0.001). The linear regression equation obtained showed a Standard Error of the Estimate (SEE) ranging from 0.164 to 0.272 (p≤0.001). There is a meaningful relationship between femur length and height, with such a strong correlation that height can be estimated by measuring femur length through linear regression equations.
Work Shifts Affect Blood Pressure in Employees In Tegal Sari Mandala II Village Azizah, Siti Nur; Putri, Sheila Dhiene
Buletin Farmatera Vol 10, No 3 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i3.26297

Abstract

Abstract: Work shifts are a work system that is widely applied in various work sectors to increase productivity. However, the implementation of this system can hurt workers' health, especially in terms of blood pressure. Based on data from Tegal Sari Mandala II Village, Medan City, it was found that there was an increase in the prevalence of hypertension in workers who worked shifts compared to workers who had fixed working hours. Hypertension in shift workers can be caused by circadian rhythm disruptions, increased cortisol levels, irregular sleep patterns, and higher stress levels. This study aims to determine the effect of work shifts on blood pressure in employees in Tegal Sari Mandala II Village. This study uses an analytical design with a cross-sectional method. The sample consisted of 100 randomly selected employees. Data was collected through blood pressure measurements using a digital sphygmomanometer. Data analysis was carried out using the Chi-Square test with univariate and bivariate methods to measure the relationship between work shifts and hypertension. The results showed a significant relationship between work shifts and hypertension incidence (p=0.001). Shift workers are more prone to hypertension than non-shift workers, with the prevalence of grade 2 hypertension being 14 employees in the shift group. Shift workers have a higher risk of hypertension than non-shift workers. Therefore, structured occupational health interventions, good sleep patterns, and education about stress management are needed to reduce the risk of hypertension in shift workers.
Understanding Rabies Disease With The Making Of Eco-Enzyme Soap For Hand Washing Lubis, Irfan Darfika; Salsabila, Saumunnisa; Aulia, Silvi; Salam, Ghurvah; Edysti, Edysti; Arhimza, Afwan
Buletin Farmatera Vol 11, No 1 (2026)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v11i1.26459

Abstract

Abstract: Rabies is a zoonotic disease caused by the rabies virus with a mortality rate of nearly 100% if not treated properly. The lack of public understanding about the dangers of rabies and the lack of awareness about the importance of hand hygiene as a preventive measure against infectious diseases such as rabies are health issues that need to be addressed through this education program. This activity was carried out as part of community service on August 21-22, 2025, at SMPN 3 Kutalimbaru Satu Atap, Namo Rube Julu Village, Deli Serdang Regency, North Sumatra Province, involving male and female students. The implementation method consisted of interactive counseling on rabies using educational posters, followed by an open discussion session and an evaluative quiz, and concluded with a workshop on making eco-enzyme soap using environmentally friendly materials. The results of the activity showed an increase in students' understanding of the transmission mechanism of rabies, the characteristics of symptoms in animals and humans, initial steps to take when exposed to the virus, and practical skills in producing eco-enzyme soap as a sustainable cleaning product alternative and as a preventive measure against rabies. Participants showed high enthusiasm and responded positively to the material presented, as well as successfully raising awareness about the importance of maintaining hand hygiene. Thus, the rabies education program combined with eco-enzyme soap making training proved effective in improving students' knowledge and practical skills, so that it is hoped that this will become a healthy habit that is consistently applied in daily activities.
Inhibition Test of Aloe Vera Extract (Aloe vera l.) Against the growth of Staphylococcus aureus Amin Lubis, Muhammad Rizqi; Mourisa, Cut
Buletin Farmatera Vol 11, No 1 (2026)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v11i1.26486

Abstract

Abstract: The use of antibacterial is a solution to treat various infectious diseases. However, the mismatch of the dose given can lead to bacterial resistance to these antibacterial substances. So, it is necessary to renew or develop natural medicines to kill bacteria and prevent resistance. One type of plant that can be used as a natural antibacterial is aloe vera (Aloe vera L.) because it contains several active substances including saponins, flavonoids, tannins and polyphenols which are thought to have antibacterial activity. This study used an experimental method with a laboratory observation approach. The technique used to measure the extra inhibition of aloe vera (Aloe vera L.) is the well diffusion method. The results showed that aloe vera extract (Aloe vera L.) in all concentration groups (20%, 40%, 60%, 80%, and 100%) had a significant difference. with a probability value (p) 0.05, which means that aloe vera extract is effective in inhibiting the growth of Staphylococcus aureus bacteria. Aloe vera extract ( Aloe Vera L) is effective in inhibiting the growth of Staphylococcus aureus.

Page 21 of 25 | Total Record : 244

 19   20   21   22   23 

Filter by Year

2016 2026


Reset
Filter By Issues
All Issue Vol 12, No 1 (2027) Vol 11, No 3 (2026) Vol 11, No 2 (2026) Vol 11, No 1 (2026) Vol 10, No 3 (2025) Vol 10, No 2 (2025) Vol 10, No 1 (2025) Vol 9, No 3 (2024) Vol 9, No 2 (2024) Vol 8, No 2 (2023) Vol 8, No 1 (2023) Vol 7, No 3 (2022) Vol 7, No 2 (2022) Vol 7, No 1 (2022) Vol 6, No 3 (2021) Vol 6, No 2 (2021) Vol 6, No 1 (2021) Vol 5, No 3 (2020) Vol 5, No 2 (2020) Vol 5, No 1 (2020) Vol 4, No 3 (2019) Vol 4, No 2 (2019) Vol 4, No 1 (2019) Vol 3, No 3 (2018) Vol 3, No 2 (2018) Vol 3, No 1 (2018): Buletin Farmatera Vol 3, No 1 (2018) Vol 2, No 3 (2017) Vol 2, No 2 (2017) Vol 2, No 1 (2017) Vol 1, No 2 (2016) Vol 1, No 1 (2016) More Issue