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Kota medan,
Sumatera utara
INDONESIA
Buletin Farmatera
Published by Universitas Muhammadiyah Sumatera Utara
ISSN : 2528410X     EISSN : 2528410X     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Arjuna Subject : -
Articles 244 Documents
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Analisis Agen Serumenolitik Cuka Apel 2,5% Dan Minyak Kelapa Pada Anak Panti Asuhan Putri Aisyiyah Kota Medan Secara In Vitro Natasya, Savira Ayu; Siregar, Siti Masliana
Buletin Farmatera Vol 10, No 1 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i1.24438

Abstract

Abstract : Cerumen impaction can occur in all types of ages, both children, adults, and the elderly which are influenced by various factors. Serumenolytic agents can soften and dissolve earwax, one of which is 2.5% Apple Vinegar and Coconut Oil used as alternatives. The purpose of this study is to analyze the effectiveness of cerumenolytic agents Apple Vinegar 2.5% and Coconut Oil as an alternative therapy for serum impaction in children of the Puteri Aisyiyah Orphanage, Medan City, in vitro.This type of research is an in vitro laboratory research using a UV-Vis spectrophotometer and a simple random sampling technique.The mean rank value for the effect of Apple Vinegar is 2.5% (32.40) while Coconut Oil is (16.60).In addition, a P-Value of r (0.000) was obtained 0.005 so that it can be stated that there is a difference in the solubility of the serumen. Which means that the effect of Apple Vinegar is 2.5% greater than that of Coconut Oil. Based on the results of the research that has been conducted, it can be concluded that 2.5% Apple Vinegar has a more reverse effectiveness on serum solubility by showing a higher average value of Coconut Oil at each trial time.
Bandage Effect Antiaging Cream Channa Striata Extract (Snakehead Fish) With Tretinoin Cream 0.1% Against Photoaging Indrawan, Yudi; Putri, Arridha Hutami
Buletin Farmatera Vol 10, No 3 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i3.24635

Abstract

Abstract: Photoaging is a skin aging process that occurs due to sun exposure causing damage to the skin. From the results of the study, it was also found that the most visible signs of premature aging were not fine lines or wrinkles, but dull skin with a percentage of 53.30%. Snakehead fish has a protein level in 100 grams of fish meat reaching 25.2 grams. The albumin level of snakehead fish is quite high up to 6.22%, and the zinc mineral content from snakehead fish reaches 1.74 mg/100 grams, with high levels of protein and albumin snakehead fish useful as photoaging therapy. This study aims to find out whether there is a difference in effect between the use of Channa striata (snakehead fish) extract cream and 0.1% tretinoin cream as photoaging therapy. This type of study is a randomized control trial using 2 groups, namely the group with the administration of snakehead fish cream test material and the group with the 0.1% tretinoin cream test material for 30 days with a total sample of 96 people, each sample will be observed at the beginning and end of the treatment using the Glombau scale. Based on the results of the study, there was no difference in effectiveness between the use of Channa Striata (snakehead fish) extract cream and 0.1% tretinoin cream on photoaging (p=1.00). There was no comparison of effectiveness between the use of Channa Striata (snakehead fish) extract cream and 0.1% tretinoin cream on photoaging.
Hubungan Kadar Asam Urat Dengan Kadar HbA1c Pada Penderita DM Tipe 2 Peserta Prolanis (Program Pengelolaan Penyakit Kronis) Munawaroh, Sri; Panjaitan, Dedi Ansyari
Buletin Farmatera Vol 10, No 2 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i2.24587

Abstract

Abstract:  Diabetes mellitus (DM) is a metabolic disease characterized by hyperglycemia due to abnormalities in insulin secretion, insulin action or both. DM cases in the world reach 463 million people, and it is estimated that it will increase in 2045 to reach 700 million people. Almost all provinces in Indonesia have seen an increase including North Sumatra, which increased from 1.8% to 2% in 2018. HbA1c has become the most widely used and accepted test to monitor glycemic control in individuals with diabetes. This study aims to determine the relationship between uric acid levels and HbA1c levels in prolanis patients with type 2 DM. Descriptive analytical research with a cross sectional research design of data collection using secondary data from medical records. The study sample was patients diagnosed with type 2 DM disease who entered the inclusion criteria and exclusion was obtained using purposive sampling with a total of 37 patients. Data analysis was carried out using a person correlation test with a meaning limit if p0.05. The results showed that there was a significant relationship between uric acid levels and HbA1c levels (p = 0.014 and r = 0.402). This means that the higher the HbA1c level, the higher the uric acid level. There is a significant relationship between uric acid levels and HbA1c levels.
Antibacterial Activity of Legundi (Vitex trifolia L.) Fruit Extract Against Lactobacillus gasseri ATCC 19992: Study In Vitro Cindykia, Assyifa; Lubis, Humairah Medina Liza
Buletin Farmatera Vol 10, No 1 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i1.22821

Abstract

Abstract: Lactobacillus species are the most frequent bacterial colonies in the human microbiome that can be found in the gastrointestinal tract, urinary tract, and vaginal microbiota. Lactobacillus gasseri is an important constituent of the female urogenital tract. if there is excessive proliferation of Lactobacillus, there will be changes in the homeostasis of the human microbiome. Homeostasis of the human microbiome can undermine the symbiotic relationship between host and microorganisms, induce physiological changes in the individual, and lead to the development of diseases such as to the development of diseases such as cancer. Legundi fruit extract was found to be cytotoxic against several lines of cancer cells and has antimicrobial activity. This research aims to determine the diameter of antibacterial inhibition of Legundi fruit extract, and determine the minimum inhibition concentration (MIC), minimum kill concentration (MKC) against Lactobacillus gasseri. This research used solid and liquid dilution and diffusion methods with concentrations of 10%, 20%, 25%, 50%, 75%, 100%, positive and negative controls. Extract of Legundi fruit can’t inhibit bacterial growth at concentrations of 10% and 20%. The longest diameter was in the positive control with streptomycin. The higher the concentration of Legundi fruit ethanol extract given, the higher the inhibition ability.    
Faktor Yang Mempengaruhi Kejadian Skabies Pada Santri Di Pondok Pesantren Hidayatullah Tanjung Morawa Br Ginting, Heni Sry Wahyuni; Faried Lubis, Taufik Akbar; Nurfadly, Nurfadly; Syafrin Lubis, Riri Arisanty
Buletin Farmatera Vol 10, No 2 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i2.24364

Abstract

Abstract: Scabies is a skin disease caused by infestation and sensitization to the hominis variant Sarcoptes scabei mite and its products.According to the Ministry of Health of the Republic of Indonesia, the prevalence of scabies in 2020 was 3.9%-6%.This states that Indonesia is still not free from scabies and is one of the infectious skin disease problems in Indonesia. The factors that cause the incidence of scabies to increase are high humidity, low sanitation, environmental density, poor personal hygiene, knowledge and attitudes and behaviors that are not supportive for a healthy lifestyle. The prevalence of scabies in Islamic boarding schools is still fairly high based on the results of the research conducted.This study aims to find out Factors Influencing the Occurrence of Scabies To students at Hidayatullah Islamic Boarding School Tanjung Morawa. cross seictional Observational analytics using a cross sectional design. Data were obtained through filling out questionnaires and physical examination of 94 samples then analyzed using univariate, bivariate analysis with the chi-square method and multivariate analysis will be carried out using multiple logistic regression tests to see the most dominant risk factors for Sarcoptes scabeii var infection. hominis. Data analysis using Chi Square showed that there was a relationship between Age and Personal hygiene Logistic regression analysis showed that the personal hygiene variable was the most dominant variable related to the event.
The RelationshipBetween Online Game Exposure and Sleep Quality in Students at SMAN 13 Medan City Azzahra, Syifa Nadya; Nuralita, Nanda Sari
Buletin Farmatera Vol 10, No 2 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i2.24505

Abstract

Abstract: Playing online games done during activities at night can come at the expense of sleep. The quality of a person's sleep is influenced by several aspects such as the duration of sleep, the time it takes to fall asleep, the frequency of waking up, and the level of sleep deprivation. Sleep disorders are a decrease in sleep quality that occurs due to daily activities, especially in adolescents. The quality of sleep can continue to decline with this bad routine continuously. This study aims to find out the effect of exposure to online games on sleep quality. The research is a cross sectional  research conducted by filling out questionnaires by 81 students and students at SMAN 13 Medan City. The data obtained will be analyzed with Chi-square. Based on data analysis, P=0.004 was obtained where there was a relationship between exposure to online games and sleep quality at SMAN 13 Medan City. There is a significant relationship between exposure to online games and sleep quality at SMAN 13 Medan City. 
Pengaruh Blue Light Filter Pada Smartphone Terhadap Tingkat Kelelahan Mata Mahasiswa Fakultas Kedokteran Universitas Muhammadiyah Sumatera Utara Savista, Taya Elsa; Adilah, Rifkah
Buletin Farmatera Vol 9, No 3 (2024)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v9i3.23375

Abstract

Abstract: The use of smartphones in the digital era like today is increasingly intense in daily life. Not only teenagers and adults, smartphones are also widely used by children, toddlers, and even babies.  Blue light filters on smartphones are believed to reduce visual disturbances that occur due to long-term smartphone use. The purpose of this study is to analyze the effect of a blue light filter on the level of eye fatigue of students of the Faculty of Medicine, University of Muhammadiyah North Sumatra (FK UMSU). This research is quasi-experimental with a pre-posttest design. A total of 154 FK UMSU students were divided into 2 groups, the Blue Light Filter Group (BLF) and the Non-Blue Light Filter Group (Non-BLF) with the same number (n1 = n2 = 77). Each group filled out a VFS (Visual Fatigue Scale) questionnaire before and after working on the visual task. The data were analyzed using the Mann-Whitney and Wilcoxon tests. The results showed that the post-test score of the level of eye fatigue in the Non-BLF group was significantly higher than that of the BLF group (P 0.001). There was a significant difference between the pre-test and post-test results of the Non-BLF Group (P 0.001), while the pre-test and post-test results of the BLF Group showed a difference but not significant (P = 0.860). This study shows that the use of blue light filters affects the level of eye fatigue. 
Speech And Language Delay Or Disorder In Children Associated With Epilepsy Ilhamsyah, Nugraha -; Sinaga, Nurcahaya -
Buletin Farmatera Vol 10, No 3 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i3.25432

Abstract

Abstract: Speech and language disorders are common clinical features often associated with neurodevelopmental disorders. Abnormal brain activity associated with epilepsy can impact the developmental trajectory of cognitive processes, such as language. Early identification of children with speech and language delays and disorders will allow for early intervention before learning and behavioural problems develop to achieve better academic and social outcomes. This study evaluates whether children with epilepsy experience speech and language disorders. Observational analysis with a cross-sectional study with patient medical record data in the outpatient clinic of a pediatric neurology consultant from January 2023 to February 2025. Risk factors were analysed bivariate and multivariate. This study found that out of 479 children with epilepsy, 331 or 62.7% experienced speech and language delay or disorders. The study concludes that a significant proportion of children with epilepsy (62.7%) experience speech and language disorders. The presence of these disorders is notably associated with a higher frequency of seizures before treatment and the existence of comorbid conditions.
Physical Activity Relate to Cardiovascular Resilience in Grade X and XI Students of SMA 01 Muhammadiyah Medan in 2022 Pakpahan, Komar; Yunafri, Andri
Buletin Farmatera Vol 10, No 2 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i2.24628

Abstract

Abstract: Physical activity is a form of any physical movement that requires the expenditure of energy produced by skeletal muscles, such as work, play or recreational activities. Cardiovascular resilience is the ability of the lungs, heart and blood vessels to deliver oxygen and nutrients to cells to meet the needs of activity. The purpose of this study is to determine the relationship between physical activity and cardiovascular resilience in students of grades X and XI of SMA 01 Muhammadiyah Medan. The research method used is an analytical method with a cross sectional approach. The number of samples used was 118 students. Physical activity was measured using  the International Physical Activity Questionnaire (IPAQ) and cardiovascular endurance was measured using the Harvard Step Test. This study had 118 respondents with students who did physical activity, the majority of whom were 81 (68.6%) students. For cardiovascular endurance, the majority is lacking, around 82 (69.5%) students. Meanwhile, for the chi-square test, a p-value of 0.023  was obtained  , so that there was a significant relationship between physical activity and cardiovascular endurance in SMA 01 Muhammadiyah Medan students. There is a significant relationship between physical activity and cardiovascular resilience in students of SMA 01 Muhammadiyah Medan.
Total Leukocyte Count And Platelet Count Are Related To TUBEX-TF Positivity Results In Typhoid Fever Patients At Dr. Pirngadi Hospital Medan City In 2018-2021 Utami, Mega Diahsyah; Irma, Fani Ade
Buletin Farmatera Vol 10, No 1 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i1.24436

Abstract

Abstract: Typhoid fever is a gastrointestinal infection caused by Sallmonellal typhi and Sallmonella serovar Paratyphi A (an important inhibitor of typhoid fever). Typhoid fever can be diagnosed based on clinical signs and symptoms, and laboratory tests. Leukopenia occurs due to the invasion of the bacterium Salmonella typhi into hematopoietic organs such as lymph nodes, tonsils, spleen, and bone marrow, thereby inhibiting hematopoiesis.The decrease in platelet production in the bone marrow is caused by viral infections, the destruction of platelet precursor cells in the bone marrow, radiation, aplastic bone marrow, bone marrow disorders or cancers, and other conditions that inhibit cell production in the bone marrow.This study aims to determine the relationship between total leukocyte count and platelet count in relation to Tubex-TF positivity in typhoid patients at RSUD dr. Pirngadi Medan from 2018 to 2021.This research uses an analytical observational method with a cross-sectional approach.The research sample consisted of typhoid patients at RSUD Dr. Pirngadi Medan from 2018-2021, which met the inclusion and exclusion criteria, totaling 71 patients.Analysis of the data was conducted using the chi-square test for both univariate and bivariate analyses.The total leukocyte count was found to be elevated in the case of a positive Tubex-TF in a patient with typhoid fever.

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