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INDONESIA
Jurnal SainHealth
Published by Universitas Maarif Hasyim Latif
ISSN : 25488333     EISSN : 25492586     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology
Jurnal SainHealth is a study journal in the field of science, health, and both of them. The journal is published by the Faculty of Health Sciences Universitas Maarif Hasyim Latif Sidoarjo.
Arjuna Subject : -
Articles 134 Documents
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UJI EFEKTIVITAS REBUSAN DAUN KAYU JAWA (Lannea coromandelica) SEBAGAI INSEKTISIDA Aedes aegypti: BOILED KAYU JAWA LEAVES (Lannea coromandelica) EFFECTIVENESS AS Aedes aegypti INSECTICIDE Pradana, Muhammad Sungging; Karimah, Sulis Tiani; Herawati, Dheasy
Jurnal SainHealth Vol. 8 No. 1 (2024): Maret 2024
Publisher : Faculty of Health Sciences Universitas Maarif Hasyim Latif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51804/jsh.v8i1.16527.25-30

Abstract

Aedes aegypti is a vector of Dengue Hemorrhagic Fever (DHF). DHF is transmitted through the bite of the Aedes aegypti mosquito which carries the virus in its body. Mosquito eradication can use natural insecticides derived from natural agent such as plants metabolites that are toxic to insects. Kayu Jawa leaf (Lannea coromandelica) is a wild plant that is easy to find. Kayu jawa leaves contain secondary metabolites such as saponins, flavonoids, polyphenols and tannins which has insecticide activity. This research was an experimental test using kayu jawa leaves (L. coromandelica) decoction at 20%, 40%, 60% and 100% to eradicate A. aegypti. Test results show that 100 % concentration of L. coromandelica leaves decoction has the greatest activity to eradicate A. aegypti. The lowest activity shown in 20% concentration. This is due to the performance of secondary metabolite compounds from L. coromandelica leaves. The conclusion of this research is L. coromandelica has an activity as an A. aegyti insecticides.
AKTIVITAS ANTIKOLESTEROL DARI KOMBINASI REBUSAN DAUN DAN BUAH SIRSAK (Annona muricata Linn): ANTICHOLESTEROL ACTIVITY OF SOURSOUP LEAF AND FRUIT CONCOCTION COMBINATION (Annona muricata Linn) Hidayatullah, Hidayatullah; Herawati, Dheasy; Gebo, Yohanes Zaitun Pebi
Jurnal SainHealth Vol. 8 No. 2 (2024): September 2024
Publisher : Faculty of Health Sciences Universitas Maarif Hasyim Latif

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Abstract

According to information released by the Indonesian Ministry of Health in 2022, 28% of Indonesia’s population suffered from cholesterol, and the condition claimed the lives of about 7.9% of all individuals worldwide. The use of medication from chemicals can cause side effects on the body, so alternative medicine from natural ingredients is needed, one of which is using a combination of soursop leaves and fruit. In this study, mice were divided into five groups: a negative control group, a positive control group and three treatment groups. The combination therapy given to each treatment group, except a negative control group consisted of boiled soursop leaves and fruit in the following ratios: 1:2, 1:1, and 2:1. The method of determination cholesterol was using immunochromatography test. The study’s findings demonstrated that the group receiving therapy in a ratio of 1:1 and 1:2 was not effective in lowering cholesterol as the group that received boiled soursop leaves and fruit in a ratio of 2:1. A statistical tests emplioyng paired T-tests revealed a significant change (p < 0.05) in cholesterol levels between pre- and post-treatment. This research support the SDGs program, namely good health well-being by utilizing soursop leaves and fruit to reduce cholesterol levels.
HUBUNGAN GEJALA KLINIS DENGAN HASIL PEMERIKSAAN NON-STRUCTURAL PROTEIN (NS1) PASIEN SUSPEK DENGUE DI PUSKESMAS SUKODADI: RELATIONSHIP BETWEEN CLINICAL SYMPTOMS AND NON-STRUCTURAL PROTEIN (NS1) EXAMINATION OF DENGUE SUSPECTED PATIENTS AT SUKODADI HEALTH CENTER Eniswatin, Ida; Herawati, Dheasy; Yusmiati, Siti Nur Husnul; Rini, Yenny Puspa
Jurnal SainHealth Vol. 8 No. 2 (2024): September 2024
Publisher : Faculty of Health Sciences Universitas Maarif Hasyim Latif

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Dengue fever is an endemic arbovirus disease that often causes morbidity and mortality. Rapid and appropriate treatment of dengue fever can be done if a rapid and specific test during the acute phase of infection can be done. An examination that has been developed is the dengue non-structural antigen (NS1) examination which can detect dengue virus infection earlier. The purpose of this study was to determine the relationship between clinical signs and symptoms with NS1 examination results in patients suspected of dengue fever at the Sukodadi Health Center. The type of research is descriptive analytical with a cross-sectional approach to 86 patients at the Sukodadi Health Center, Lamongan Regency using a simple random sampling technique. Data collection was carried out on patient medical records based on the results of clinical signs and symptoms of the examination and the results of the NS1 examination. The collected data were analyzed using the Chi-Square test, with a significance level of p <0.05. The results of the study showed that most patients (72.1%) were diagnosed with suspected dengue fever, most (79.1%) had negative NS1 examination results, and the Chi-Square test results obtained x count = 8.812, and p = 0.003 (<0.05), then H0 was rejected, meaning that there was a relationship between clinical signs and symptoms with NS1 examination results in patients with suspected dengue fever. The conclusion of this study is there is a significant relationship between clinical signs and symptoms with NS1 examination results in patients with suspected dengue fever
KOMBINASI UJI LARVASIDA EKSTRAK DAUN BELUNTAS (Pluchea indica linn) DAN BAWANG PUTIH (Allium Sativum) DALAM MEMBUNUH LARVA Aedes aegypti: COMBINATION OF LARVACIDE TEST OF BELUNTAS LEAF EXTRACT (Pluchea indica linn) AND GARLIC (Allium Sativum) IN KILLING Aedes aegypti LARVAE Hariyanti, Firda Natasya; Chamid, Abdul; Prasetya, Indra Adi Wira; Suryani, Elsa Mega; Pradana, Muhammad Sungging
Jurnal SainHealth Vol. 8 No. 2 (2024): September 2024
Publisher : Faculty of Health Sciences Universitas Maarif Hasyim Latif

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Aedes aegypti is a type of mosquito that causes dengeu hemorrhagic fever as the main carrier (primary vector) of dengeu virus. This disease is very common in Indonesia, efforts to eradicate mosquito larvae are relatively cheap, simple by means of public health counseling and eradication of mosquito nests using insecticides. The purpose of this study was to determine the effectiveness of the combination of beluntas leaf extract (Pluchea indica linn) and garlic (Allium satisum) in killing Aedes aegypti mosquito larvae at concentrations of 10%, 20%, 50%, and 100% for 24 hours. This type of study used experimental research with a research sample of 400 Aedes aegypti mosquito larvae. The results showed that the combination of beluntas leaf extract (Pluche indica linn) and garlic (Allium satisum) has effectiveness as a larvicide of Aedes aegypti instar III. The effective concentration on the combination of beluntas leaf extract (Pluchea indica linn) and garlic (Allium sativum) is 50% within 24 hours.
KESESUAIAN HASIL PEMERIKSAAN FINE NEEDLE ASPIRATION BIOPSY (FNAB) DENGAN PEMERIKSAAN HISTOPATOLOGY DALAM MENENTUKAN TUMOR PAYUDARA: ACCORDANCE OF FINE NEEDLE ASPIRATION BIOPSY (FNAB) EXAMINATION RESULTS WITH HISTOPATHOLOGY EXAMINATION IN DETERMINING BREAST TUMORS Rate, Inggit Wigati; Santoso, Setyo Dwi; Anggrenani, Tri Endah
Jurnal SainHealth Vol. 8 No. 2 (2024): September 2024
Publisher : Faculty of Health Sciences Universitas Maarif Hasyim Latif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51804/jsh.v8i2.16753.38-46

Abstract

Breast tumors are a collection of cells in the breast tissue that divide rapidly so that they grow and become numerous. Breast tumors are divided into 2, namely benign tumors and malignant tumors (cancer). One way to establish a diagnosis of breast tumors is by examining Fine Needle Aspiration Biopsy (FNAB) and histopathology which are the gold standard of diagnosis. The purpose of this study was to determine the suitability of FNAB examination with Histopathology in determining benign or malignant breast tumors, as well as to determine the sensitivity, specificity, positive predictive value, negative predictive value and accuracy. This study used a descriptive research method with a sample size of 96 samples in 2022. The results of the study showed that there was a match between the results of the FNAB examination and the histopathology examination in determining benign or malignant breast tumors. In this study, FNAB had a sensitivity value of 83.78%, a specificity of 95.45%, a positive predictive value of 98.41%, a negative predictive value of 63.64% and an accuracy of 86.46%. It was concluded that the Fine Needle Aspiration Biopsy (FNAB) examination was consistent with the Histopathology examination in determining tumors
GAMBARAN HEMOGLOBIN DAN NEUTROFIL PASIEN KEMOTERAPI KANKER PAYUDARA DI ONKOLOGI CENTER RSUD Dr. SOETOMO SURABAYA: HEMOGLOBIN AND NEUTROPHIL OF BREAST CANCER CHEMOTHERAPYPATIENTS AT THE ONCOLOGY CENTER OF Dr. SOETOMO HOSPITAL, SURABAYA Rachmaningtyas, Arie; Sundari, Titik; Rini, Yenny Puspa; Wijayanti, Christina Destri Wiwis
Jurnal SainHealth Vol. 8 No. 2 (2024): September 2024
Publisher : Faculty of Health Sciences Universitas Maarif Hasyim Latif

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Abstract

Breast cancer management is chemotherapy. One of the negative impacts of chemotherapy is affecting hemoglobin and neutrophils. This study aims to determine the description of Hemoglobin levels and Neutrophil counts in breast cancer patients undergoing chemotherapy stage 1 (early) and stage 6 (late) at the Oncology Center of Dr. Soetomo Hospital, Surabaya. This study is an observational study with a retrospective design. The sample in this study was some breast cancer patients undergoing chemotherapy stage 1 (early) and 6 (late) at the Oncology Center of Dr. Soetomo Hospital, Surabaya, which was taken as many as 25 people by purposive sampling. Purposive sampling. The study was conducted in the Oncology Center laboratory of Dr. Soetomo Hospital, Surabaya. This study was conducted from October to December 2022. The results of the study showed that breast cancer patients undergoing stage 1 chemotherapy mostly had normal hemoglobin as many as 13 people (52%) with an average Hb level of ± 12.34 g / dL and normal neutrophils as many as 23 people (92%) with an average neutrophil level of ± 4412 cells / µL. In stage 6 chemotherapy, most had low hemoglobin as many as 13 people (52%) with an average Hb level of ± 11.78 g / dL and normal neutrophils as many as 24 people (96%) with an average number of neutrophils of 4202.68 cells / µL.
PERBANDINGAN UJI Treponema pallidum Haemagglutination Assay (TPHA) DAN IMUNOKROMATOGRAFI SEBAGAI DETEKSI SIFILIS di PUSKESMAS MEDAENG: COMPARISON OF Treponema pallidum Haemagglutination Assay (TPHA) TEST AND IMMUNOCHROMATOGRAPHY AS SYPHILIS DETECTION AT MEDAENG PUBLIC HEALTH CENTER Romadhon, Desi Fitriatur; Wijayanti, Christina Destri Wiwis; Sundari, Titik; Harmoko, Deni
Jurnal SainHealth Vol. 8 No. 2 (2024): September 2024
Publisher : Faculty of Health Sciences Universitas Maarif Hasyim Latif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51804/jsh.v8i2.16861.65-69

Abstract

Syphilis is a sexually transmitted infection caused by the bacteria Treponema pallidum. Syphilis detection can be done using the Treponema pallidum Haemagglutination Assay (TPHA) method and immunochromatography. Treponema pallidum Haemaglutination Assay (TPHA) is a specific antibody test to detect Treponema pallidum but the process is long and expensive, compared to fast and relatively cheap immunochromatography. This study aimed to compare the Treponema pallidum Haemagglutination Assay (TPHA) method and immunochromatography as syphilis detection by looking at their positive and negative reaction percentage. The type of research used was descriptive-analytical observation. The results of the Treponema pallidum Haemagglutination Assay (TPHA) examination were positive for 10 samples (50%) and negative for 10 samples (50%). Meanwhile, positive immunochromatography was in 8 samples (40%) and negative for 12 samples (60%). It can be concluded that TPHA and immunochromatography have a different result. Keywords: syphilis, immunochromatography, TPHA, sensitivity, specificity
AKTIVITAS PROBIOTIK BAKTERI Enterococcus lactis SA8 ASAL SUSU KERBAU SUMBAWA (Bubalus bubalis): PROBIOTIC ACTIVITY OF Enterococcus lactis SA8 BACTERIA FROM SUMBAWA BUFFALO MILK (Bubalus bubalis) Harmoko, Deni; Ningrum, Rizka Kusuma; Pati, Andra Alvianto Umbu
Jurnal SainHealth Vol. 8 No. 2 (2024): September 2024
Publisher : Faculty of Health Sciences Universitas Maarif Hasyim Latif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51804/jsh.v8i2.16905.70-75

Abstract

The most important quality of lactic acid bacteria as probiotics used for additives is tolerance to bile salts and low pH, which allows bacteria to survive, grow, and provide therapeutic effects in the digestive tract. Probiotics are living microorganisms that can provide optimal health effects when consumed in certain amounts, even exceeding general nutrition. Lactic acid bacteria are probiotic bacteria that can provide good health benefits when consumed regularly. The growth and production of lactic acid in LAB are influenced by pH and bile salts, this ability distinguishes between species of lactic acid bacteria. LAB must have The main physiological requirements of probiotic bacteria are their resistance and tolerance to low pH and bile salts. This study aims to test E. lactis SA8 bacteria from Sumbawa Buffalo milk to determine their probiotic activity through tests on pH resistance and their ability to live in bile salts. E. lactis SA8 bacteria have probiotic activity, which is indicated by their ability to withstand low pH, and the results of bile salt testing show the highest viability at a concentration of 0.3% with a density of 9.8x107 CFU/mL, which is a sign of probiotic bacteria.  Keywords: Probiotics, lactic acid bacteria, Enterococcus lactis SA8, pH and bile salt tests
HUBUNGAN INDEKS MASSA TUBUH TERHADAP KADAR HEMOGLOBIN DAN HEMATOKRIT SEBAGAI PENANDA ANEMIA PADA SISWI DI SMA NEGERI 1 KALIANGET: RELATIONSHIP BETWEEN BODY MASS INDEX AND HEMOGLOBIN AND HEMATOCRITE LEVELS AS MARKERS OF ANEMIA IN FEMALE STUDENTS AT STATE SENIOR HIGH SCHOOL 1 KALIANGET Ajie, Devy Verliantina; Herawati, Dheasy; Wijaya, Halik
Jurnal SainHealth Vol. 9 No. 1 (2025): Maret 2025
Publisher : Faculty of Health Sciences Universitas Maarif Hasyim Latif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51804/jsh.v9i1.16907.35-40

Abstract

Iron deficiency anemia is a condition of decreased health quality that is susceptible to adolescent girls. Someone who has a BMI below normal has a risk of iron metabolism disorders due to indications of low micronutrient intake. Iron deficiency causes low hemoglobin levels because iron is an important substance in the hemoglobin molecule. Hct examination is carried out as a simple screening for anemia and accompanies the results of the Hb examination to prove the level of accuracy of the diagnosis. This study aims to investigate the relationship between BMI and hemoglobin and hematocrit levels in adolescents in a population in the Kalianget Health Center area with the sample determined being female students at SMA Negeri 1 Kalianget, Sumenep. The design used in this study was analytical with a cross-sectional approach. Capillary blood sampling of 96 female students was carried out using the POCT method to measure Hb and Hct. In this study, a bivariate analysis was conducted to determine the relationship between body mass index (BMI) and Hb and Hct using the chi square test. The results of the Chi-square test analysis, a p value of 0.000 <0.05 was obtained for the relationship between BMI and Hb and a p value of 0.001 <0.05 for the relationship between BMI and Hct. Conclusion of this research is There is a relationship between BMI and Hb and Hct of students at SMAN 1 Kalianget.
PERBANDINGAN KADAR HEMOGLOBIN IBU HAMIL MENGGUNAKAN ALAT HEMOCHROMA PLUS METODE POCT DENGAN ALAT HEMATOLOGI SEMI OTOMATIK: THE DIFFERENCE IN HEMOGLOBIN LEVELS IN PREGNANT WOMEN USING THE HEMOCHROMA PLUS POCT METHOD WITH A SEMI-AUTOMATIC HEMATOLOGY DEVICE Malihah, Malihah; Sundari, Titik; Yusmiati, Siti Nur Husnul
Jurnal SainHealth Vol. 9 No. 1 (2025): Maret 2025
Publisher : Faculty of Health Sciences Universitas Maarif Hasyim Latif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51804/jsh.v9i1.16908.27-34

Abstract

Anemia is a condition where hemoglobin levels, hematocrit and red blood cell counts decrease below normal values. This research aims to find out. A simple examination of hemoglobin levels using an HB Meter with a Hemachroma Plus Tool, the POCT method, has the advantage of only requiring a small amount of capillary blood sample. Research title "Comparison of Hemoglobin Levels of Pregnant Women Using the Hemochroma Plus POCT Method and Semi- Automatic Hematology Equipment in the Lenteng Community Health Center Laboratory, Sumenep Regency." Number of Research Subjects: 50 ANC pregnant women. Capillary blood examination material for POCT devices and K3EDTA venous blood for semi-automatic hematology devices. Data processing used the Independent T Test and the results obtained were p=0.001 (?>0.05), there was a higher difference in hemoglobin levels on the POCT tool compared to the semi- automatic hematology tool. The average value of the POCT Hb level is (12.18) or 12.2 G/dL and the hematology analyzer tool's average value of the HB level is 11.29 or 11.3 G/dL. Conclusion: The HB level value of the POCT tool is higher 8% compared to semi-automatic hematology equipment

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